Rras (RAS related) - Rat Genome Database

Name: Rras
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rras (RAS related) Ictidomys tridecemlineatus

Analyze

Symbol:

Rras

Name:

RAS related

RGD ID:

12473497

Description:

ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN cell migration (ortholog); negative regulation of Schwann cell migration (ortholog); Schwann cell migration (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH COVID-19 (ortholog); developmental and epileptic encephalopathy 12 (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras-related protein R-Ras; related RAS viral (r-ras) oncogene homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RRAS (RAS related)	NCBI	Ortholog
Mus musculus (house mouse):	Rras (related RAS viral (r-ras) oncogene)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Rras (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rras (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RRAS (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RRAS (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RRAS (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RRAS (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rras (RAS related)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,838,491 - 21,842,354 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,456,290 - 3,460,788 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,456,681 - 3,460,537 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

developmental and epileptic encephalopathy 12 (ISO)

genetic disease (ISO)

juvenile myelomonocytic leukemia (ISO)

Noonan syndrome (ISO)

Prostatic Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (IEA,ISO)

face morphogenesis (IEA)

leukocyte differentiation (IEA)

negative regulation of Schwann cell migration (IEA,ISO)

positive regulation of angiogenesis (IEA)

positive regulation of endothelial cell migration (IEA)

positive regulation of endothelial cell-matrix adhesion via fibronectin (IEA)

positive regulation of vasculogenesis (IEA)

Ras protein signal transduction (IEA)

regulation of ERK1 and ERK2 cascade (IEA)

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

Schwann cell migration (IEA,ISO)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

GDP binding (IEA)

GTP binding (IEA)

GTPase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein-containing complex binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ephrin - ephrin receptor bidirectional signaling axis (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Rras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,838,491 - 21,842,354 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,456,290 - 3,460,788 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,456,681 - 3,460,537 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RRAS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,635,292 - 49,640,143 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,635,292 - 49,640,143 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,138,549 - 50,143,400 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,830,364 - 54,835,212 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	54,830,363 - 54,835,212	NCBI
Celera	19	47,007,883 - 47,012,731 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,515,612 - 46,520,460 (-)	NCBI		HuRef
CHM1_1	19	50,140,333 - 50,145,181 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,635,325 - 52,640,178 (-)	NCBI		T2T-CHM13v2.0

Rras
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,665,686 - 44,671,070 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,667,385 - 44,671,071 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,017,942 - 45,021,646 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,017,961 - 45,021,647 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,273,377 - 52,277,014 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,886,049 - 44,889,686 (+)	NCBI		MGSCv36	mm8
Celera	7	40,469,567 - 40,473,202 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.08	NCBI

Rras
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,637,061 - 104,640,841 (+)	NCBI		GRCr8
mRatBN7.2	1	95,500,582 - 95,504,362 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,500,566 - 95,504,357 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,885,980 - 100,889,760 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,358,646 - 109,362,426 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,649,041 - 102,652,821 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,012,822 - 101,016,720 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,012,822 - 101,016,720 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,077,775 - 102,081,673 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,490,730 - 95,495,462 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,568,807 - 95,573,563 (+)	NCBI
Celera	1	89,761,925 - 89,765,705 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Rras
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,244,658 - 1,248,774 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,244,658 - 1,248,774 (+)	NCBI	ChiLan1.0	ChiLan1.0

RRAS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,752,559 - 55,757,421 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,673,302 - 57,678,161 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,649,892 - 46,654,754 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,569,465 - 55,571,444 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,569,749 - 55,573,721 (-)	Ensembl	panpan1.1		panPan2

RRAS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,895,413 - 106,899,265 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,895,408 - 106,899,222 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,479,192 - 106,483,049 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,416,876 - 107,420,728 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,416,878 - 107,420,685 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,089,085 - 107,092,934 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,731,174 - 106,735,018 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,572,304 - 107,576,157 (+)	NCBI		UU_Cfam_GSD_1.0

RRAS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,680,600 - 54,684,719 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,680,596 - 54,684,714 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,409,620 - 50,413,729 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RRAS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,810,411 - 42,815,504 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,810,339 - 42,815,479 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,754,154 - 22,759,266 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rras
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,633,326 - 4,637,938 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,632,812 - 4,637,938 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000001861 ⟹ ENSSTOP00000001661

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936664	3,456,290 - 3,460,788 (-)	Ensembl

RefSeq Acc Id:

XM_005336682 ⟹ XP_005336739

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	21,838,491 - 21,842,354 (-)	NCBI
SpeTri2.0	NW_004936664	3,456,681 - 3,460,537 (-)	NCBI

Sequence:

show sequence

CCCCTTGGCTGTAGCAGAGGCGGCAGCAGCGGTGGCGACATGAGCAGCGGGGCGGCGTCCGGGA
CTGGGCGGGGGCGGCCCCGGGGCGGGGGGCCGGGACCCGGGGACCCCCCGCCCAGCGAGACACA
CAAGCTGGTGGTCGTGGGCGGCGGCGGCGTGGGCAAGAGCGCACTGACCATCCAGTTCATCCAG
TCCTACTTCGTGTCTGACTATGACCCCACCATCGAGGACTCCTACACGAAGATCTGCACGGTGG
ATGGCATCCCAGCCCGGCTGGACATCCTGGACACCGCGGGCCAGGAGGAATTTGGGGCCATGAG
GGAGCAGTATATGCGGGCTGGCCATGGTTTCCTGCTGGTGTATGCCATTAACGACCGGCAAAGT
TTCAACGAAGTGGGCAAACTCTTCACTCAGATCCTCCGAGTCAAGGACCGTGATGACTTCCCCA
TTGTGCTGGTTGGGAATAAGGCAGATCTGGAGACACAGCGCCAGGTCCACCGATCTGAAGCATC
TGCTTTCAGCGCCTCCCACCACGTGGCCTACTTTGAGGCATCAGCCAAACTGCGTCTCAACGTG
GATGAGGCTTTCGAGCAGCTGGTGCGGGCCGTCAGGAAATACCAGGAACAAGAGCTCCCACCCA
GCCCTCCCAGCGCCCCCAGGAAGAAGGATGGGGGCTGCCCCTGTGTCCTGCTGTAGCCAGGATA
GGAGAAGTGACCAGCACAAGCTGTCGGGACCAGCTGCCTTGCACCTTGCTGTGTGGCCTGAGGC
CCTGGCCGAGCCTCAGTTTCCTCCTCTGGGTCTCCCAGGACACACTACACCTTTTACCCTTATT
TCCCAGCCTCCTCTGGGCCAACGCCACTGTGTGCCTTTTGCCAACACCTCTTTTCCCCACCCAA
GCCCCTGGTGAGGTGAGGGGTTCCAGGGTCACTGCTGTATATAACTCCCCACCCCCAGAAAAAT
AAACGTCACTGCCAAAGTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005336739	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000001661.2
GenBank Protein	KAG3256521	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005336739 ⟸ XM_005336682

- UniProtKB:

I3LZC6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIED
SYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVYAINDRQSFNEVGKLFTQILR
VKDRDDFPIVLVGNKADLETQRQVHRSEASAFSASHHVAYFEASAKLRLNVDEAFEQLVRAVRK
YQEQELPPSPPSAPRKKDGGCPCVLL

hide sequence

RefSeq Acc Id:

ENSSTOP00000001661 ⟸ ENSSTOT00000001861

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000001860	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000001861.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/TrEMBL
	Small_GTPase_Ras-type	UniProtKB/TrEMBL
NCBI Gene	Rras	ENTREZGENE
PANTHER	PTHR24070	UniProtKB/TrEMBL
	RAS-RELATED PROTEIN R-RAS	UniProtKB/TrEMBL
Pfam	Ras	UniProtKB/TrEMBL
PRINTS	RASTRNSFRMNG	UniProtKB/TrEMBL
PROSITE	RAB	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
SMART	RAB	UniProtKB/TrEMBL
	RAN	UniProtKB/TrEMBL
	RAS	UniProtKB/TrEMBL
	RHO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	I3LZC6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-08-08	Rras	RAS related		related RAS viral (r-ras) oncogene homolog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)