Kcne3 (potassium voltage-gated channel subfamily E regulatory subunit 3) - Rat Genome Database

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Gene: Kcne3 (potassium voltage-gated channel subfamily E regulatory subunit 3) Ictidomys tridecemlineatus
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Symbol: Kcne3
Name: potassium voltage-gated channel subfamily E regulatory subunit 3
RGD ID: 12471857
Description: ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN negative regulation of delayed rectifier potassium channel activity (ortholog); negative regulation of voltage-gated potassium channel activity (ortholog); positive regulation of voltage-gated calcium channel activity (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); Brugada syndrome (ortholog); Brugada syndrome 6 (ortholog); FOUND IN basolateral part of cell (ortholog); voltage-gated potassium channel complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel subfamily E regulatory subunit 3, transcript variant X1; potassium voltage-gated channel subfamily E regulatory subunit 3, transcript variant X2; potassium voltage-gated channel subfamily E regulatory subunit 3, transcript variant X3; potassium voltage-gated channel, Isk-related family, member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,478,039 - 3,478,350 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,477,313 - 3,487,580 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcne3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,478,039 - 3,478,350 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,477,313 - 3,487,580 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNE3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381174,454,841 - 74,467,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1174,454,841 - 74,467,729 (-)EnsemblGRCh38hg38GRCh38
GRCh371174,165,886 - 74,178,594 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361173,843,534 - 73,856,248 (-)NCBINCBI36Build 36hg18NCBI36
Build 341173,843,805 - 73,850,798NCBI
Celera1171,472,396 - 71,485,109 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1170,461,201 - 70,473,937 (-)NCBIHuRef
CHM1_11174,049,426 - 74,062,143 (-)NCBICHM1_1
T2T-CHM13v2.01174,384,260 - 74,396,980 (-)NCBIT2T-CHM13v2.0
Kcne3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,825,714 - 99,834,076 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl799,825,709 - 99,834,076 (+)EnsemblGRCm39 Ensembl
GRCm387100,176,507 - 100,184,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7100,176,502 - 100,184,869 (+)EnsemblGRCm38mm10GRCm38
MGSCv377107,327,207 - 107,333,374 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367100,052,780 - 100,058,947 (+)NCBIMGSCv36mm8
Celera7100,513,245 - 100,519,198 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.33NCBI
Kcne3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,936,035 - 163,942,998 (+)NCBIGRCr8
mRatBN7.21154,523,903 - 154,530,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,523,830 - 154,532,020 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,518,249 - 162,525,206 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,698,347 - 169,705,304 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,571,923 - 162,578,879 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,189,934 - 165,196,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,189,985 - 165,196,948 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,390,138 - 171,397,804 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,558,044 - 157,565,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,636,337 - 157,643,300 (+)NCBI
Celera1152,607,926 - 152,614,889 (+)NCBICelera
Cytogenetic Map1q32NCBI
Kcne3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541417,166,546 - 17,200,353 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541417,166,537 - 17,200,385 (+)NCBIChiLan1.0ChiLan1.0
KCNE3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2975,396,558 - 75,409,080 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11176,440,593 - 76,453,426 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01169,527,663 - 69,540,236 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,832,858 - 72,845,399 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,835,048 - 72,835,359 (-)Ensemblpanpan1.1panPan2
KCNE3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,860,727 - 23,872,194 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,871,648 - 23,871,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2123,625,823 - 23,638,780 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02124,063,194 - 24,076,168 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2124,074,135 - 24,074,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,860,571 - 23,873,532 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02124,057,896 - 24,070,858 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,975,487 - 23,988,456 (+)NCBIUU_Cfam_GSD_1.0
KCNE3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl98,810,720 - 8,822,494 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.198,810,716 - 8,822,191 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.299,649,248 - 9,660,859 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNE3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1165,699,558 - 65,710,305 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl165,700,156 - 65,700,467 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,150,565 - 60,161,017 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcne3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248172,513,539 - 2,606,682 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248172,593,649 - 2,607,462 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000012388   ⟹   ENSSTOP00000011099
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364983,478,039 - 3,478,350 (-)Ensembl
RefSeq Acc Id: XM_005323192   ⟹   XP_005323249
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBI
SpeTri2.0NW_0049364983,477,313 - 3,487,580 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725088   ⟹   XP_021580763
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBI
SpeTri2.0NW_0049364983,477,313 - 3,487,580 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725089   ⟹   XP_021580764
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBI
SpeTri2.0NW_0049364983,477,313 - 3,487,580 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040284934   ⟹   XP_040140868
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494761,876,838 - 61,888,024 (-)NCBI
RefSeq Acc Id: XP_005323249   ⟸   XM_005323192
- UniProtKB: I3MJ20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580764   ⟸   XM_021725089
- UniProtKB: I3MJ20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580763   ⟸   XM_021725088
- UniProtKB: I3MJ20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040140868   ⟸   XM_040284934
- UniProtKB: I3MJ20 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000011099   ⟸   ENSSTOT00000012388


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012391 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012388.1 UniProtKB/TrEMBL
InterPro K_chnl_KCNE UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNE3 UniProtKB/TrEMBL
NCBI Gene Kcne3 ENTREZGENE
PANTHER PTHR15282 UniProtKB/TrEMBL
  PTHR15282:SF6 UniProtKB/TrEMBL
Pfam ISK_Channel UniProtKB/TrEMBL
PRINTS KCNE3CHANNEL UniProtKB/TrEMBL
  KCNECHANNEL UniProtKB/TrEMBL
UniProt I3MJ20 ENTREZGENE, UniProtKB/TrEMBL