E2f7 (E2F transcription factor 7) - Rat Genome Database

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Gene: E2f7 (E2F transcription factor 7) Ictidomys tridecemlineatus
Analyze
Symbol: E2f7
Name: E2F transcription factor 7
RGD ID: 12471143
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN negative regulation of cell population proliferation (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Disease Progression (ortholog); genetic disease (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN nuclear speck (inferred); nucleus (inferred); RNA polymerase II transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor E2F7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,476,352 - 40,522,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365685,206,135 - 5,244,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365685,206,135 - 5,245,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
E2f7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,476,352 - 40,522,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365685,206,135 - 5,244,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365685,206,135 - 5,245,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E2F7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381277,021,251 - 77,065,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1277,021,248 - 77,065,569 (-)EnsemblGRCh38hg38GRCh38
GRCh371277,415,031 - 77,459,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,939,157 - 75,983,491 (-)NCBINCBI36Build 36hg18NCBI36
Celera1277,080,472 - 77,124,821 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1274,467,815 - 74,512,166 (-)NCBIHuRef
CHM1_11277,380,867 - 77,425,221 (-)NCBICHM1_1
T2T-CHM13v2.01276,999,082 - 77,043,421 (-)NCBIT2T-CHM13v2.0
E2f7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910110,580,799 - 110,623,245 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10110,581,300 - 110,623,245 (+)EnsemblGRCm39 Ensembl
GRCm3810110,745,439 - 110,787,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10110,745,439 - 110,787,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710110,182,521 - 110,224,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610110,149,578 - 110,191,483 (+)NCBIMGSCv36mm8
MGSCv3610110,874,175 - 110,915,960 (+)NCBIMGSCv36mm8
Celera10112,679,553 - 112,721,244 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1057.74NCBI
E2f7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,036,881 - 48,079,055 (+)NCBIGRCr8
mRatBN7.2746,150,533 - 46,192,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,151,293 - 46,192,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,049,531 - 48,091,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,252,659 - 50,294,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,030,385 - 50,072,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,275,659 - 53,318,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,275,676 - 53,316,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,286,853 - 53,328,709 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4749,689,755 - 49,751,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1749,710,871 - 49,771,412 (+)NCBI
Celera742,963,883 - 43,003,790 (+)NCBICelera
Cytogenetic Map7q22NCBI
E2f7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540516,148,480 - 16,186,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540516,148,640 - 16,187,272 (-)NCBIChiLan1.0ChiLan1.0
E2F7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21085,057,718 - 85,102,581 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11285,054,112 - 85,098,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01274,540,049 - 74,582,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11277,388,950 - 77,433,262 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1277,388,950 - 77,433,262 (-)Ensemblpanpan1.1panPan2
E2F7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,856,093 - 19,895,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,857,227 - 19,895,225 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1520,339,285 - 20,381,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01520,194,252 - 20,236,238 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1520,195,500 - 20,234,063 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,793,846 - 19,832,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,851,678 - 19,893,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,980,571 - 20,022,547 (-)NCBIUU_Cfam_GSD_1.0
E2F7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5104,127,731 - 104,163,212 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15104,126,924 - 104,163,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25109,254,285 - 109,289,365 (+)NCBISscrofa10.2Sscrofa10.2susScr3
E2F7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11172,598,220 - 72,642,366 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1172,599,353 - 72,641,420 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037172,897,900 - 172,942,501 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E2f7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475021,010,339 - 21,063,757 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475021,010,347 - 21,063,655 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000007886   ⟹   ENSSTOP00000007058
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365685,206,135 - 5,244,450 (-)Ensembl
RefSeq Acc Id: XM_005330440   ⟹   XP_005330497
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494540,482,950 - 40,522,277 (+)NCBI
SpeTri2.0NW_0049365685,206,135 - 5,245,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040280286   ⟹   XP_040136220
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494540,476,352 - 40,522,277 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005330497 (Get FASTA)   NCBI Sequence Viewer  
  XP_040136220 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000007058.3
GenBank Protein KAG3291333 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005330497   ⟸   XM_005330440
- Peptide Label: isoform X2
- UniProtKB: I3MAL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136220   ⟸   XM_040280286
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000007058   ⟸   ENSSTOT00000007886
Protein Domains
E2F/DP family winged-helix DNA-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007887 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007886.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro E2F UniProtKB/TrEMBL
  E2F_WHTH_DNA-bd_dom UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene E2f7 ENTREZGENE
PANTHER PTHR12081 UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR E2F7 UniProtKB/TrEMBL
Pfam E2F_TDP UniProtKB/TrEMBL
SMART E2F_TDP UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt I3MAL6 ENTREZGENE, UniProtKB/TrEMBL