Pusl1 (pseudouridine synthase like 1) - Rat Genome Database

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Gene: Pusl1 (pseudouridine synthase like 1) Ictidomys tridecemlineatus
Analyze
Symbol: Pusl1
Name: pseudouridine synthase like 1
RGD ID: 12469402
Description: ENCODES a protein that exhibits isomerase activity (inferred); pseudouridine synthase activity (inferred); RNA binding (inferred); INVOLVED IN pseudouridine synthesis (inferred); tRNA processing (inferred); tRNA pseudouridine synthesis (inferred); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); dilated cardiomyopathy 1LL (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pseudouridylate synthase like 1; pseudouridylate synthase-like 1; tRNA pseudouridine synthase-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,629,752 - 27,632,651 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367371,833,798 - 1,836,696 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367371,833,298 - 1,836,101 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pusl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,629,752 - 27,632,651 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367371,833,798 - 1,836,696 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367371,833,298 - 1,836,101 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PUSL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,308,597 - 1,311,677 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,308,597 - 1,311,677 (+)EnsemblGRCh38hg38GRCh38
GRCh3711,243,977 - 1,247,057 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,233,857 - 1,236,920 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411,283,916 - 1,286,979NCBI
Celera11,334,084 - 1,337,147 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1515,603 - 518,659 (+)NCBIHuRef
CHM1_111,231,025 - 1,234,088 (+)NCBICHM1_1
T2T-CHM13v2.01740,148 - 743,228 (+)NCBIT2T-CHM13v2.0
Pusl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,973,314 - 155,976,231 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,972,336 - 155,976,238 (-)EnsemblGRCm39 Ensembl
GRCm384155,888,857 - 155,891,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,887,879 - 155,891,781 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,262,966 - 155,265,871 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,732,413 - 154,735,569 (-)NCBIMGSCv36mm8
Celera4158,159,833 - 158,162,725 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.66NCBI
Pusl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,773,284 - 171,782,893 (-)NCBIGRCr8
mRatBN7.25166,497,643 - 166,500,647 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,496,755 - 166,500,611 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,202,453 - 169,205,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,023,874 - 171,026,878 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,986,406 - 170,989,410 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,326,755 - 173,339,934 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,336,034 - 173,340,026 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,811,652 - 176,815,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,745,715 - 172,749,571 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,697,479 - 164,701,335 (-)NCBICelera
Cytogenetic Map5q36NCBI
Pusl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,491,506 - 9,494,520 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,491,613 - 9,494,746 (-)NCBIChiLan1.0ChiLan1.0
PUSL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,915,523 - 226,919,100 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,612,211 - 225,615,302 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,263 - 66,360 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,263,656 - 1,266,661 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,263,656 - 1,266,661 (+)Ensemblpanpan1.1panPan2
PUSL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,482,802 - 56,485,778 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,482,363 - 56,485,783 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,558,999 - 56,562,109 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,684,922 - 56,688,026 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,684,952 - 56,687,513 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,675,637 - 56,678,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,567,929 - 56,571,032 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,957,933 - 56,961,044 (+)NCBIUU_Cfam_GSD_1.0
PUSL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,593,959 - 63,599,019 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,593,539 - 63,596,921 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,091,967 - 58,094,995 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PUSL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,139,479 - 130,142,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,139,480 - 130,142,342 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605434,705,841 - 34,709,175 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pusl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,299,449 - 8,302,320 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248188,299,449 - 8,302,333 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000001781   ⟹   ENSSTOP00000001589
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367371,833,798 - 1,836,696 (-)Ensembl
RefSeq Acc Id: XM_040287742   ⟹   XP_040143676
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,792 - 27,632,651 (+)NCBI
RefSeq Acc Id: XM_040287743   ⟹   XP_040143677
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,793 - 27,632,651 (+)NCBI
RefSeq Acc Id: XM_040287744   ⟹   XP_040143678
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,794 - 27,632,651 (+)NCBI
RefSeq Acc Id: XM_040287745   ⟹   XP_040143679
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,752 - 27,632,651 (+)NCBI
RefSeq Acc Id: XM_040287746   ⟹   XP_040143680
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,791 - 27,632,651 (+)NCBI
RefSeq Acc Id: XM_040287747   ⟹   XP_040143681
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,629,793 - 27,632,651 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_040143679   ⟸   XM_040287745
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040143680   ⟸   XM_040287746
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040143676   ⟸   XM_040287742
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040143681   ⟸   XM_040287747
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040143677   ⟸   XM_040287743
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040143678   ⟸   XM_040287744
- Peptide Label: isoform X3
- UniProtKB: I3LZ74 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000001589   ⟸   ENSSTOT00000001781
Protein Domains
Pseudouridine synthase I TruA alpha/beta


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001783 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001781.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.580 UniProtKB/TrEMBL
  3.30.70.660 UniProtKB/TrEMBL
InterPro PsdUridine_synth_cat_dom_sf UniProtKB/TrEMBL
  PsdUridine_synth_TruA UniProtKB/TrEMBL
  PsdUridine_synth_TruA_a/b_dom UniProtKB/TrEMBL
  PsdUridine_synth_TruA_C UniProtKB/TrEMBL
  TruA/RsuA/RluB/E/F_N UniProtKB/TrEMBL
NCBI Gene Pusl1 ENTREZGENE
PANTHER PTHR11142 UniProtKB/TrEMBL
  TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 UniProtKB/TrEMBL
Pfam PseudoU_synth_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF55120 UniProtKB/TrEMBL
UniProt I3LZ74 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-09-18 Pusl1  pseudouridine synthase like 1    pseudouridylate synthase like 1  Symbol and/or name change 5135510 APPROVED
2018-05-01 Pusl1  pseudouridylate synthase like 1    pseudouridylate synthase-like 1  Symbol and/or name change 5135510 APPROVED