Enah (ENAH actin regulator) - Rat Genome Database

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Gene: Enah (ENAH actin regulator) Ictidomys tridecemlineatus
Analyze
Symbol: Enah
Name: ENAH actin regulator
RGD ID: 12469290
Description: ENCODES a protein that exhibits actin binding (inferred); profilin binding (inferred); SH3 domain binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); actin polymerization or depolymerization (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN filopodium (ortholog); lamellipodium (ortholog); neuron projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: enabled homolog; enabled homolog (Drosophila); ENAH, actin regulator; ENAH, actin regulator, transcript variant X1; ENAH, actin regulator, transcript variant X2; ENAH, actin regulator, transcript variant X3; ENAH, actin regulator, transcript variant X4; ENAH, actin regulator, transcript variant X5; protein enabled homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934452,269,764 - 52,414,557 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365262,332,664 - 2,477,833 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365262,332,344 - 2,477,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Enah
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934452,269,764 - 52,414,557 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365262,332,664 - 2,477,833 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365262,332,344 - 2,477,827 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENAH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,486,829 - 225,653,878 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1225,486,765 - 225,653,142 (-)EnsemblGRCh38hg38GRCh38
GRCh371225,674,531 - 225,840,825 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361223,741,157 - 223,907,468 (-)NCBINCBI36Build 36hg18NCBI36
Build 341221,981,268 - 222,147,580NCBI
Celera1198,865,129 - 199,031,134 (-)NCBICelera
Cytogenetic Map1q42.12NCBI
HuRef1196,193,432 - 196,359,068 (-)NCBIHuRef
CHM1_11226,946,878 - 227,113,178 (-)NCBICHM1_1
T2T-CHM13v2.01224,675,098 - 224,841,848 (-)NCBIT2T-CHM13v2.0
Enah
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391181,723,949 - 181,848,132 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1181,723,949 - 181,847,555 (-)EnsemblGRCm39 Ensembl
GRCm381181,896,384 - 182,027,556 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1181,896,384 - 182,019,990 (-)EnsemblGRCm38mm10GRCm38
MGSCv371183,834,576 - 183,950,111 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361183,742,188 - 183,856,336 (-)NCBIMGSCv36mm8
Celera1188,957,160 - 189,017,504 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map184.93NCBI
Enah
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81396,149,437 - 96,269,841 (-)NCBIGRCr8
mRatBN7.21393,617,747 - 93,738,119 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1393,626,944 - 93,740,955 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1396,123,053 - 96,243,421 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01397,522,946 - 97,643,298 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01394,705,126 - 94,825,478 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013100,297,421 - 100,415,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13100,300,054 - 100,414,226 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013105,277,627 - 105,392,796 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41397,919,690 - 98,025,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11398,108,627 - 98,214,089 (-)NCBI
Celera1393,161,661 - 93,266,823 (-)NCBICelera
Cytogenetic Map13q26NCBI
Enah
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955520308,070 - 371,922 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955520310,482 - 374,800 (+)NCBIChiLan1.0ChiLan1.0
ENAH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2123,885,156 - 24,045,244 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1123,834,054 - 23,996,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01200,956,988 - 201,113,242 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11205,963,067 - 206,115,672 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1205,963,247 - 206,115,672 (-)Ensemblpanpan1.1panPan2
ENAH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1739,105,024 - 39,250,126 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl739,105,039 - 39,247,595 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha738,587,078 - 38,732,144 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0738,938,972 - 39,084,406 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl738,938,017 - 39,084,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1738,778,555 - 38,923,489 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0738,786,801 - 38,932,026 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0739,056,619 - 39,201,943 (+)NCBIUU_Cfam_GSD_1.0
ENAH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1013,446,426 - 13,609,303 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11013,439,772 - 13,609,347 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21016,217,878 - 16,292,117 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENAH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1254,134,853 - 4,264,392 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl254,134,852 - 4,260,928 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660554,119,116 - 4,284,897 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enah
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248356,292,808 - 6,442,349 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013359218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013359219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013359220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040278245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000024473   ⟹   ENSSTOP00000015903
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365262,336,064 - 2,477,642 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000025977   ⟹   ENSSTOP00000019440
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365262,336,064 - 2,477,642 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000034205   ⟹   ENSSTOP00000024788
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365262,332,664 - 2,477,833 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000038656   ⟹   ENSSTOP00000026511
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365262,332,664 - 2,477,827 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000038875   ⟹   ENSSTOP00000026426
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365262,336,064 - 2,401,750 (-)Ensembl
RefSeq Acc Id: XM_040278228   ⟹   XP_040134162
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278229   ⟹   XP_040134163
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278230   ⟹   XP_040134164
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,269,764 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278231   ⟹   XP_040134165
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278232   ⟹   XP_040134166
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278233   ⟹   XP_040134167
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278234   ⟹   XP_040134168
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278235   ⟹   XP_040134169
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,113 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278236   ⟹   XP_040134170
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278237   ⟹   XP_040134171
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278238   ⟹   XP_040134172
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,372,589 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278239   ⟹   XP_040134173
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,372,589 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278240   ⟹   XP_040134174
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,387,779 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278242   ⟹   XP_040134176
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278243   ⟹   XP_040134177
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278244   ⟹   XP_040134178
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
RefSeq Acc Id: XM_040278245   ⟹   XP_040134179
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934452,270,594 - 52,414,557 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_040134164   ⟸   XM_040278230
- Peptide Label: isoform X3
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134169   ⟸   XM_040278235
- Peptide Label: isoform X8
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134162   ⟸   XM_040278228
- Peptide Label: isoform X1
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134166   ⟸   XM_040278232
- Peptide Label: isoform X5
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134163   ⟸   XM_040278229
- Peptide Label: isoform X2
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134168   ⟸   XM_040278234
- Peptide Label: isoform X7
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134176   ⟸   XM_040278242
- Peptide Label: isoform X14
- UniProtKB: A0A287CZ14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134178   ⟸   XM_040278244
- Peptide Label: isoform X16
- UniProtKB: A0A287CZ14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134165   ⟸   XM_040278231
- Peptide Label: isoform X4
- UniProtKB: I3N4Z4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134170   ⟸   XM_040278236
- Peptide Label: isoform X9
- UniProtKB: I3N4Z4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134167   ⟸   XM_040278233
- Peptide Label: isoform X6
- UniProtKB: I3MUV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134171   ⟸   XM_040278237
- Peptide Label: isoform X10
- UniProtKB: I3MUV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134177   ⟸   XM_040278243
- Peptide Label: isoform X15
- UniProtKB: A0A287CZ14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134179   ⟸   XM_040278245
- Peptide Label: isoform X17
- UniProtKB: A0A287CZ14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134172   ⟸   XM_040278238
- Peptide Label: isoform X11
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134173   ⟸   XM_040278239
- Peptide Label: isoform X12
- UniProtKB: A0A287CU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134174   ⟸   XM_040278240
- Peptide Label: isoform X13
RefSeq Acc Id: ENSSTOP00000015903   ⟸   ENSSTOT00000024473
RefSeq Acc Id: ENSSTOP00000019440   ⟸   ENSSTOT00000025977
RefSeq Acc Id: ENSSTOP00000024788   ⟸   ENSSTOT00000034205
RefSeq Acc Id: ENSSTOP00000026511   ⟸   ENSSTOT00000038656
RefSeq Acc Id: ENSSTOP00000026426   ⟸   ENSSTOT00000038875
Protein Domains
WH1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028215 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024473.2 UniProtKB/TrEMBL
  ENSSTOT00000025977.2 UniProtKB/TrEMBL
  ENSSTOT00000034205.1 UniProtKB/TrEMBL
  ENSSTOT00000038656.1 UniProtKB/TrEMBL
  ENSSTOT00000038875.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  VASP_sf UniProtKB/TrEMBL
  VASP_tetra UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/TrEMBL
NCBI Gene Enah ENTREZGENE
PANTHER PROTEIN ENABLED HOMOLOG UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam VASP_tetra UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF118370 UniProtKB/TrEMBL
UniProt A0A287CU36 ENTREZGENE, UniProtKB/TrEMBL
  A0A287CYS9_ICTTR UniProtKB/TrEMBL
  A0A287CZ14 ENTREZGENE, UniProtKB/TrEMBL
  I3MUV8 ENTREZGENE, UniProtKB/TrEMBL
  I3N4Z4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Enah  ENAH actin regulator    ENAH, actin regulator  Symbol and/or name change 5135510 APPROVED
2017-05-30 Enah  ENAH, actin regulator    enabled homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED