Emp3 (epithelial membrane protein 3 (MAM blood group)) - Rat Genome Database

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Gene: Emp3 (epithelial membrane protein 3 (MAM blood group)) Ictidomys tridecemlineatus
Analyze
Symbol: Emp3
Name: epithelial membrane protein 3 (MAM blood group) (Ensembl:epithelial membrane protein 3)
RGD ID: 12468976
Description: INVOLVED IN apoptotic process (inferred); bleb assembly (inferred); ASSOCIATED WITH genetic disease (ortholog); Prostatic Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epithelial membrane protein 3; epithelial membrane protein 3, transcript variant X1; epithelial membrane protein 3, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934920,850,007 - 20,853,482 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,468,269 - 2,471,675 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,467,240 - 2,471,672 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Emp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934920,850,007 - 20,853,482 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,468,269 - 2,471,675 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,467,240 - 2,471,672 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,325,552 - 48,330,553 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,321,509 - 48,330,553 (+)EnsemblGRCh38hg38GRCh38
GRCh371948,828,809 - 48,833,810 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,520,454 - 53,525,622 (+)NCBINCBI36Build 36hg18NCBI36
Build 341953,520,453 - 53,525,622NCBI
Celera1945,693,863 - 45,699,044 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,209,377 - 45,214,558 (+)NCBIHuRef
CHM1_11948,830,732 - 48,835,916 (+)NCBICHM1_1
T2T-CHM13v2.01951,319,698 - 51,324,699 (+)NCBIT2T-CHM13v2.0
Emp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,567,447 - 45,570,850 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,567,447 - 45,570,828 (-)EnsemblGRCm39 Ensembl
GRCm38745,918,023 - 45,921,426 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,918,023 - 45,921,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv37753,173,393 - 53,176,796 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,786,106 - 45,789,446 (-)NCBIMGSCv36mm8
Celera741,383,035 - 41,386,440 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.6NCBI
Emp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,525,086 - 105,528,370 (-)NCBIGRCr8
mRatBN7.2196,388,651 - 96,391,946 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,388,652 - 96,391,988 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,774,797 - 101,777,974 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01110,246,785 - 110,249,962 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,537,150 - 103,540,327 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,900,731 - 101,903,948 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,900,733 - 101,903,910 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,979,695 - 102,982,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,389,783 - 96,392,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,467,893 - 96,471,071 (-)NCBI
Celera190,641,302 - 90,644,479 (-)NCBICelera
Cytogenetic Map1q22NCBI
Emp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555592,117,200 - 2,121,366 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555592,117,200 - 2,121,366 (-)NCBIChiLan1.0ChiLan1.0
EMP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,429,929 - 54,435,117 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,356,040 - 56,361,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,326,302 - 45,331,462 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11953,919,933 - 53,925,147 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,919,986 - 53,925,147 (+)Ensemblpanpan1.1panPan2
EMP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,901,778 - 107,905,912 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,901,781 - 107,905,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,423,282 - 107,427,399 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,426,213 - 108,430,346 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,426,216 - 108,430,232 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,092,642 - 108,096,761 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,739,405 - 107,743,526 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,575,501 - 108,579,626 (-)NCBIUU_Cfam_GSD_1.0
EMP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,757,776 - 53,761,833 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,757,513 - 53,761,833 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,394,027 - 49,398,349 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EMP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,591,145 - 41,596,723 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl641,591,020 - 41,596,951 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,368,887 - 21,374,758 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,432,166 - 5,436,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,432,204 - 5,437,514 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000002593   ⟹   ENSSTOP00000002319
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366642,468,269 - 2,471,675 (+)Ensembl
RefSeq Acc Id: XM_013363536   ⟹   XP_013218990
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934920,850,007 - 20,853,482 (+)NCBI
SpeTri2.0NW_0049366642,467,240 - 2,471,672 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013363537   ⟹   XP_013218991
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934920,850,062 - 20,853,482 (+)NCBI
SpeTri2.0NW_0049366642,468,272 - 2,471,672 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013218990 (Get FASTA)   NCBI Sequence Viewer  
  XP_013218991 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002319.2
GenBank Protein KAG3256400 (Get FASTA)   NCBI Sequence Viewer  
  KAG3256401 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013218990   ⟸   XM_013363536
- UniProtKB: I3M0Q5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013218991   ⟸   XM_013363537
- UniProtKB: I3M0Q5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000002319   ⟸   ENSSTOT00000002593


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002595 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002593.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro EMP_3 UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
  PMP22_EMP_MP20 UniProtKB/TrEMBL
NCBI Gene Emp3 ENTREZGENE
PANTHER EPITHELIAL MEMBRANE PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR10671:SF8 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PRINTS EPMEMFAMILY UniProtKB/TrEMBL
  EPMEMPROT3 UniProtKB/TrEMBL
PROSITE PMP22_1 UniProtKB/TrEMBL
  PMP22_2 UniProtKB/TrEMBL
UniProt I3M0Q5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-11-07 Emp3  epithelial membrane protein 3 (MAM blood group)  Emp3  epithelial membrane protein 3  Symbol and/or name change 5135510 APPROVED