Stxbp5l (syntaxin binding protein 5L) - Rat Genome Database

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Gene: Stxbp5l (syntaxin binding protein 5L) Ictidomys tridecemlineatus
Analyze
Symbol: Stxbp5l
Name: syntaxin binding protein 5L (Ensembl:syntaxin binding protein 5 like)
RGD ID: 12468004
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); myosin II binding (inferred); syntaxin binding (inferred); INVOLVED IN glucose homeostasis (ortholog); negative regulation of insulin secretion (ortholog); regulation of exocytosis (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); genetic disease (ortholog); Primary Lymphedema with Myelodysplasia (ortholog); FOUND IN neuromuscular junction (ortholog); neuronal dense core vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: syntaxin binding protein 5 like; syntaxin binding protein 5 like, transcript variant X1; syntaxin binding protein 5 like, transcript variant X2; syntaxin binding protein 5 like, transcript variant X3; syntaxin binding protein 5 like, transcript variant X4; syntaxin binding protein 5 like, transcript variant X5; syntaxin binding protein 5 like, transcript variant X6; syntaxin binding protein 5 like, transcript variant X7; syntaxin binding protein 5 like, transcript variant X8; syntaxin binding protein 5 like, transcript variant X9; syntaxin-binding protein 5-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,630,023 - 129,958,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365367,563,607 - 7,886,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365367,563,585 - 7,885,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Stxbp5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,630,023 - 129,958,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365367,563,607 - 7,886,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365367,563,585 - 7,885,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STXBP5L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383120,908,205 - 121,424,761 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3120,908,072 - 121,424,761 (+)EnsemblGRCh38hg38GRCh38
GRCh373120,627,052 - 121,143,608 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363122,109,609 - 122,621,338 (+)NCBINCBI36Build 36hg18NCBI36
Build 343122,109,772 - 122,621,336NCBI
Celera3119,036,797 - 119,553,405 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3118,001,087 - 118,518,020 (+)NCBIHuRef
CHM1_13120,590,662 - 121,107,318 (+)NCBICHM1_1
T2T-CHM13v2.03123,628,071 - 124,144,685 (+)NCBIT2T-CHM13v2.0
Stxbp5l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391636,927,437 - 37,205,377 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1636,935,304 - 37,205,324 (-)EnsemblGRCm39 Ensembl
GRCm381637,107,075 - 37,385,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1637,114,942 - 37,384,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv371637,107,393 - 37,385,044 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361637,053,135 - 37,304,162 (-)NCBIMGSCv36mm8
Celera1637,516,531 - 37,793,303 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.32NCBI
Stxbp5l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81176,838,839 - 77,167,852 (+)NCBIGRCr8
mRatBN7.21163,334,667 - 63,654,270 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1163,334,667 - 63,657,014 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,147,113 - 72,466,676 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01164,809,343 - 65,128,900 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01163,858,949 - 64,163,917 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,246,624 - 66,566,331 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,316,606 - 66,566,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,337,663 - 69,661,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,129,572 - 65,455,115 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,147,137 - 65,512,704 (+)NCBI
Celera1162,831,916 - 63,131,512 (+)NCBICelera
Cytogenetic Map11q21NCBI
Stxbp5l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542720,390,060 - 20,760,043 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542720,390,060 - 20,760,043 (+)NCBIChiLan1.0ChiLan1.0
STXBP5L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22118,876,875 - 119,384,107 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13118,881,653 - 119,388,885 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03118,022,061 - 118,529,311 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13124,932,104 - 125,440,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3124,932,110 - 125,434,515 (+)Ensemblpanpan1.1panPan2
STXBP5L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13324,320,625 - 24,702,782 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3324,320,650 - 24,697,153 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3324,348,396 - 24,732,582 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03324,559,393 - 24,947,448 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3324,559,417 - 24,940,776 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13324,360,228 - 24,745,739 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03324,400,286 - 24,781,893 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03324,964,788 - 25,344,701 (+)NCBIUU_Cfam_GSD_1.0
STXBP5L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13139,123,209 - 139,445,470 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113139,116,931 - 139,491,227 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213148,628,557 - 148,835,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STXBP5L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12259,460,278 - 59,938,228 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2259,465,870 - 59,938,129 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041106,369,563 - 106,865,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stxbp5l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473126,820,018 - 27,305,447 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473126,815,873 - 27,305,344 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005327640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005327641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021727971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040270298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005726906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000009943   ⟹   ENSSTOP00000008922
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365367,563,607 - 7,886,038 (+)Ensembl
RefSeq Acc Id: XM_005327640   ⟹   XP_005327697
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
SpeTri2.0NW_0049365367,563,585 - 7,885,908 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005327641   ⟹   XP_005327698
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,428 (-)NCBI
SpeTri2.0NW_0049365367,563,585 - 7,884,958 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040270289   ⟹   XP_040126223
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270291   ⟹   XP_040126225
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270292   ⟹   XP_040126226
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,430 (-)NCBI
RefSeq Acc Id: XM_040270293   ⟹   XP_040126227
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270294   ⟹   XP_040126228
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270295   ⟹   XP_040126229
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270296   ⟹   XP_040126230
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270297   ⟹   XP_040126231
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XM_040270298   ⟹   XP_040126232
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,631,295 - 129,958,429 (-)NCBI
RefSeq Acc Id: XR_005726906
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,630,023 - 129,958,429 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005327697   ⟸   XM_005327640
- Peptide Label: isoform X10
- UniProtKB: I3MEJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005327698   ⟸   XM_005327641
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_040126226   ⟸   XM_040270292
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040126232   ⟸   XM_040270298
- Peptide Label: isoform X9
RefSeq Acc Id: XP_040126230   ⟸   XM_040270296
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040126227   ⟸   XM_040270293
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040126231   ⟸   XM_040270297
- Peptide Label: isoform X8
RefSeq Acc Id: XP_040126229   ⟸   XM_040270295
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040126225   ⟸   XM_040270291
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040126228   ⟸   XM_040270294
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040126223   ⟸   XM_040270289
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000008922   ⟸   ENSSTOT00000009943
Protein Domains
v-SNARE coiled-coil homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009925 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009943.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro Lethal2_giant UniProtKB/TrEMBL
  Lgl_C_dom UniProtKB/TrEMBL
  LLGL2 UniProtKB/TrEMBL
  V_SNARE_CC UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Stxbp5l ENTREZGENE
PANTHER LETHAL 2 GIANT LARVAE PROTEIN UniProtKB/TrEMBL
  SYNTAXIN-BINDING PROTEIN 5-LIKE UniProtKB/TrEMBL
Pfam Lgl_C UniProtKB/TrEMBL
  LLGL UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS LETHAL2GIANT UniProtKB/TrEMBL
PROSITE V_SNARE UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt I3MEJ3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-13 Stxbp5l  syntaxin binding protein 5L  Stxbp5l  syntaxin binding protein 5 like  Symbol and/or name change 5135510 APPROVED