Ephb4 (EPH receptor B4) - Rat Genome Database

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Gene: Ephb4 (EPH receptor B4) Ictidomys tridecemlineatus
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Symbol: Ephb4
Name: EPH receptor B4
RGD ID: 12455958
Description: ENCODES a protein that exhibits ephrin receptor activity (ortholog); transmembrane receptor protein tyrosine kinase activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell adhesion (ortholog); cell migration involved in sprouting angiogenesis (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH Breast Neoplasms (ortholog); cancer (ortholog); Capillary Malformation-Arteriovenous Malformation 2 (ortholog); FOUND IN integral component of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ephrin type-B receptor 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,224,893 - 133,241,678 (+)NCBI
SpeTri2.0NW_004936543794,837 - 811,637 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Ephb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,224,893 - 133,241,678 (+)NCBI
SpeTri2.0NW_004936543794,837 - 811,637 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7100,802,565 - 100,827,523 (-)EnsemblGRCh38hg38GRCh38
GRCh387100,802,565 - 100,827,523 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377100,400,187 - 100,425,145 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,238,123 - 100,263,079 (-)NCBINCBI36hg18NCBI36
Build 347100,044,837 - 100,069,794NCBI
Celera795,130,741 - 95,155,701 (-)NCBI
Cytogenetic Map7q22.1NCBI
HuRef795,030,927 - 95,055,371 (-)NCBIHuRef
CHM1_17100,330,777 - 100,355,761 (-)NCBICHM1_1
CRA_TCAGchr7v2799,759,792 - 99,784,748 (-)NCBI
Ephb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,348,371 - 137,372,784 (+)NCBIGRCm39mm39
GRCm39 Ensembl5137,348,371 - 137,376,931 (+)Ensembl
GRCm385137,350,109 - 137,374,522 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,350,109 - 137,378,669 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,791,337 - 137,815,750 (+)NCBIGRCm37mm9NCBIm37
MGSCv365137,579,945 - 137,604,277 (+)NCBImm8
Celera5134,333,170 - 134,357,666 (+)NCBICelera
Cytogenetic Map5G2NCBI
Ephb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21219,326,411 - 19,351,667 (-)NCBI
Rnor_6.0 Ensembl1222,393,330 - 22,417,980 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01222,393,338 - 22,418,332 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,407,927 - 24,432,912 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,128,289 - 21,153,496 (-)NCBICelera
Cytogenetic Map12q12NCBI
Ephb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573132,328 - 152,595 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573132,328 - 150,879 (+)NCBIChiLan1.0ChiLan1.0
EPHB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17106,223,427 - 106,248,022 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,223,427 - 106,248,022 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0792,827,550 - 92,852,462 (-)NCBIMhudiblu_PPA_v0panPan3
EPHB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,925,303 - 8,943,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,924,686 - 8,942,324 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,631,634 - 10,649,370 (+)NCBI
ROS_Cfam_1.068,861,650 - 8,879,327 (+)NCBI
UMICH_Zoey_3.168,714,171 - 8,731,877 (+)NCBI
UNSW_CanFamBas_1.068,692,052 - 8,709,742 (+)NCBI
UU_Cfam_GSD_1.068,874,020 - 8,891,770 (+)NCBI
EPHB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,668,858 - 8,689,766 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,671,052 - 8,689,778 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.238,097,951 - 8,116,183 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHB4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,389,884 - 12,416,746 (+)NCBI
ChlSab1.1 Ensembl2812,389,942 - 12,416,920 (+)Ensembl
Vero_WHO_p1.0NW_0236660703,908,378 - 3,935,258 (-)NCBI
Ephb4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474016,320,672 - 16,339,454 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005328473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005328473   ⟹   XP_005328530
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344133,224,893 - 133,241,678 (+)NCBI
SpeTri2.0NW_004936543794,837 - 811,637 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005328530 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3259883 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005328530   ⟸   XM_005328473
- UniProtKB: A0A287CZ82 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013737 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000012314 UniProtKB/TrEMBL
  ENSSTOP00000026645 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013743 UniProtKB/TrEMBL
  ENSSTOT00000041858 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.60.120.260 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro EPH-B4_SAM UniProtKB/TrEMBL
  Eph_TM UniProtKB/TrEMBL
  EphB4_rcpt_lig-bd UniProtKB/TrEMBL
  Ephrin_rcpt_lig-bd_dom UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Galactose-bd-like UniProtKB/TrEMBL
  Growth_fac_rcpt_ UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr-kin_ephrin_A/B_rcpt-like UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_ephrin_rcpt UniProtKB/TrEMBL
  Tyr_kinase_rcpt_V_CS UniProtKB/TrEMBL
NCBI Gene Ephb4 ENTREZGENE
Pfam EphA2_TM UniProtKB/TrEMBL
  Ephrin_lbd UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PIRSF TyrPK_ephrin_receptor UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE EPH_LBD UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_1 UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART EPH_lbd UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A287CZ82 ENTREZGENE, UniProtKB/TrEMBL
  I3MLL6_ICTTR UniProtKB/TrEMBL