Stra6 (signaling receptor and transporter of retinol STRA6) - Rat Genome Database

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Gene: Stra6 (signaling receptor and transporter of retinol STRA6) Ictidomys tridecemlineatus
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Symbol: Stra6
Name: signaling receptor and transporter of retinol STRA6 (Ensembl:stimulated by retinoic acid 6)
RGD ID: 12454470
Description: ENCODES a protein that exhibits retinal binding (inferred); retinol binding (inferred); retinol transmembrane transporter activity (inferred); INVOLVED IN establishment of localization in cell (ortholog); positive regulation of receptor signaling pathway via JAK-STAT (ortholog); response to retinoic acid (ortholog); PARTICIPATES IN retinoic acid metabolic pathway; ASSOCIATED WITH Anophthalmia (ortholog); Bardet-Biedl syndrome (ortholog); Bloom syndrome (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor for retinol uptake STRA6; stimulated by retinoic acid 6; stimulated by retinoic acid gene 6 protein homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,376,111 - 115,490,544 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,224,859 - 33,245,030 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647133,224,174 - 33,245,076 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Stra6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,376,111 - 115,490,544 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,224,859 - 33,245,030 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647133,224,174 - 33,245,076 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STRA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381574,179,466 - 74,212,259 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1574,179,466 - 74,212,267 (-)EnsemblGRCh38hg38GRCh38
GRCh371574,471,807 - 74,502,046 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,258,860 - 72,282,245 (-)NCBINCBI36Build 36hg18NCBI36
Build 341572,258,862 - 72,282,245NCBI
Celera1551,418,988 - 51,448,552 (-)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1551,265,478 - 51,295,736 (-)NCBIHuRef
CHM1_11574,590,002 - 74,620,238 (-)NCBICHM1_1
T2T-CHM13v2.01572,045,386 - 72,078,184 (-)NCBIT2T-CHM13v2.0
Stra6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,971,076 - 58,061,287 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl957,971,071 - 58,061,279 (+)EnsemblGRCm39 Ensembl
GRCm38958,063,793 - 58,154,004 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl958,063,788 - 58,153,996 (+)EnsemblGRCm38mm10GRCm38
MGSCv37957,976,895 - 58,001,804 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36957,927,486 - 57,952,090 (+)NCBIMGSCv36mm8
Celera955,363,368 - 55,388,212 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.63NCBI
Stra6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8867,444,757 - 67,464,719 (+)NCBIGRCr8
mRatBN7.2858,548,899 - 58,568,861 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl858,549,736 - 58,568,860 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx864,079,448 - 64,099,415 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0862,357,008 - 62,376,974 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0860,221,574 - 60,241,541 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0862,925,364 - 62,944,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,925,357 - 62,944,437 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,701,454 - 62,720,528 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,920,772 - 61,939,791 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1861,939,822 - 61,958,845 (+)NCBI
Celera858,013,586 - 58,032,719 (+)NCBICelera
Cytogenetic Map8q24NCBI
Stra6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,580,662 - 3,602,600 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,579,081 - 3,602,538 (+)NCBIChiLan1.0ChiLan1.0
STRA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21663,403,177 - 63,433,441 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11567,566,763 - 67,597,027 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01553,117,891 - 53,150,790 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11572,740,868 - 72,773,802 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1572,741,482 - 72,770,876 (-)Ensemblpanpan1.1panPan2
STRA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,331,834 - 37,359,449 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,331,832 - 37,353,529 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,267,455 - 37,295,072 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03037,538,888 - 37,566,524 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3037,538,924 - 37,560,014 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13037,491,016 - 37,518,679 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03037,516,933 - 37,544,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03037,772,499 - 37,800,122 (-)NCBIUU_Cfam_GSD_1.0
STRA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl759,318,011 - 59,347,266 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1759,317,930 - 59,347,274 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2763,936,184 - 63,965,508 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STRA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1269,275,317 - 9,311,302 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl269,278,303 - 9,311,475 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048132,311,962 - 132,346,794 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stra6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624781389,481 - 413,728 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624781304,890 - 413,655 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000038913   ⟹   ENSSTOP00000031539
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647133,224,859 - 33,245,030 (-)Ensembl
RefSeq Acc Id: XM_040274409   ⟹   XP_040130343
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,490,544 (-)NCBI
RefSeq Acc Id: XM_040274410   ⟹   XP_040130344
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,408,795 (-)NCBI
RefSeq Acc Id: XM_040274411   ⟹   XP_040130345
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,408,000 (-)NCBI
RefSeq Acc Id: XM_040274412   ⟹   XP_040130346
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,408,795 (-)NCBI
RefSeq Acc Id: XM_040274413   ⟹   XP_040130347
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,396,967 (-)NCBI
RefSeq Acc Id: XM_040274414   ⟹   XP_040130348
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,403,884 (-)NCBI
RefSeq Acc Id: XM_040274415   ⟹   XP_040130349
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640115,376,111 - 115,397,211 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_040130343   ⟸   XM_040274409
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130344   ⟸   XM_040274410
- Peptide Label: isoform X2
- UniProtKB: A0A287DDC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040130346   ⟸   XM_040274412
- Peptide Label: isoform X2
- UniProtKB: A0A287DDC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040130345   ⟸   XM_040274411
- Peptide Label: isoform X2
- UniProtKB: A0A287DDC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040130348   ⟸   XM_040274414
- Peptide Label: isoform X2
- UniProtKB: A0A287DDC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040130349   ⟸   XM_040274415
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040130347   ⟸   XM_040274413
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000031539   ⟸   ENSSTOT00000038913


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000030322 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000038913.1 UniProtKB/TrEMBL
InterPro STRA6 UniProtKB/TrEMBL
NCBI Gene Stra6 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 180 UniProtKB/TrEMBL
  PTHR21444:SF16 UniProtKB/TrEMBL
Pfam RBP_receptor UniProtKB/TrEMBL
UniProt A0A287DDC9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-16 Stra6  signaling receptor and transporter of retinol STRA6  Stra6  stimulated by retinoic acid 6  Symbol and/or name change 5135510 APPROVED