Rin2 (Ras and Rab interactor 2) - Rat Genome Database

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Gene: Rin2 (Ras and Rab interactor 2) Ictidomys tridecemlineatus
Analyze
Symbol: Rin2
Name: Ras and Rab interactor 2
RGD ID: 12453000
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); guanyl-nucleotide exchange factor activity (inferred); small GTPase binding (inferred); INVOLVED IN positive regulation of endothelial cell migration (inferred); positive regulation of endothelial cell-matrix adhesion via fibronectin (inferred); positive regulation of vasculogenesis (inferred); ASSOCIATED WITH genetic disease (ortholog); Macrocephaly, Alopecia, Cutis Laxa, and Scoliosis (ortholog); FOUND IN cytosol (inferred); endocytic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,946,228 - 152,171,904 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936485377,396 - 556,616 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936485377,562 - 556,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,946,228 - 152,171,904 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936485377,396 - 556,616 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936485377,562 - 556,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382019,757,599 - 20,002,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2019,757,606 - 20,002,457 (+)EnsemblGRCh38hg38GRCh38
GRCh372019,738,902 - 19,983,100 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362019,818,210 - 19,931,100 (+)NCBINCBI36Build 36hg18NCBI36
Build 342019,818,209 - 19,931,100NCBI
Celera2019,944,265 - 20,057,119 (+)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2019,829,693 - 19,944,819 (+)NCBIHuRef
CHM1_12019,867,581 - 19,983,477 (+)NCBICHM1_1
T2T-CHM13v2.02019,809,879 - 20,056,735 (+)NCBIT2T-CHM13v2.0
Rin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392145,613,647 - 145,729,536 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2145,517,135 - 145,729,536 (+)EnsemblGRCm39 Ensembl
GRCm382145,771,727 - 145,887,616 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2145,675,215 - 145,887,616 (+)EnsemblGRCm38mm10GRCm38
MGSCv372145,611,852 - 145,713,352 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362145,477,584 - 145,579,054 (+)NCBIMGSCv36mm8
Celera2147,020,636 - 147,123,470 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.25NCBI
Rin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83153,540,147 - 153,756,897 (+)NCBIGRCr8
mRatBN7.23133,086,858 - 133,303,604 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,086,749 - 133,303,604 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3137,019,265 - 137,213,109 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03145,603,344 - 145,797,204 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03143,306,511 - 143,500,360 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03139,871,330 - 140,087,679 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3139,894,331 - 140,087,678 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,294,631 - 146,510,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,307,538 - 134,503,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13134,383,397 - 134,408,088 (+)NCBI
Celera3131,974,768 - 132,168,991 (+)NCBICelera
Cytogenetic Map3q41NCBI
Rin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541527,984,449 - 28,133,214 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541527,953,670 - 28,130,122 (+)NCBIChiLan1.0ChiLan1.0
RIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,644,990 - 20,890,589 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12020,683,986 - 20,887,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02019,716,071 - 19,960,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12019,683,013 - 19,925,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2019,811,284 - 19,924,256 (+)Ensemblpanpan1.1panPan2
RIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1243,345,221 - 3,563,716 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl243,343,087 - 3,563,772 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha243,373,428 - 3,591,885 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,753,523 - 3,972,256 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,751,358 - 3,944,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1243,349,198 - 3,567,538 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0243,452,567 - 3,671,029 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,730,425 - 3,949,191 (-)NCBIUU_Cfam_GSD_1.0
RIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1727,807,244 - 28,058,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11727,941,333 - 28,058,150 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,441,716 - 32,456,755 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1248,768,647 - 49,020,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl248,905,779 - 49,021,368 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660783,553,322 - 3,805,798 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,441,972 - 20,536,464 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474120,338,306 - 20,537,500 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005320430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021723133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005729680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000014726   ⟹   ENSSTOP00000013191
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936485377,396 - 500,791 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000040052   ⟹   ENSSTOP00000026739
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936485377,396 - 556,616 (-)Ensembl
RefSeq Acc Id: XM_005320430   ⟹   XP_005320487
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,946,228 - 152,051,275 (-)NCBI
SpeTri2.0NW_004936485377,562 - 483,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723128   ⟹   XP_021578803
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,054,277 (-)NCBI
SpeTri2.0NW_004936485377,562 - 485,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723129   ⟹   XP_021578804
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,165,029 (-)NCBI
SpeTri2.0NW_004936485377,562 - 556,611 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723131   ⟹   XP_021578806
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,165,029 (-)NCBI
SpeTri2.0NW_004936485377,562 - 500,773 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723132   ⟹   XP_021578807
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,051,567 (-)NCBI
SpeTri2.0NW_004936485377,562 - 483,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021723133   ⟹   XP_021578808
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,011,490 (-)NCBI
SpeTri2.0NW_004936485377,562 - 442,776 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275764   ⟹   XP_040131698
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,165,029 (-)NCBI
RefSeq Acc Id: XM_040275765   ⟹   XP_040131699
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,165,029 (-)NCBI
RefSeq Acc Id: XM_040275766   ⟹   XP_040131700
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,171,904 (-)NCBI
RefSeq Acc Id: XM_040275767   ⟹   XP_040131701
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,054,116 (-)NCBI
RefSeq Acc Id: XM_040275768   ⟹   XP_040131702
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,947,450 - 152,011,492 (-)NCBI
RefSeq Acc Id: XR_005729680
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640151,951,559 - 152,165,029 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005320487   ⟸   XM_005320430
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578804   ⟸   XM_021723129
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578806   ⟸   XM_021723131
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021578803   ⟸   XM_021723128
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578807   ⟸   XM_021723132
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021578808   ⟸   XM_021723133
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_040131700   ⟸   XM_040275766
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131698   ⟸   XM_040275764
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131699   ⟸   XM_040275765
- Peptide Label: isoform X1
- UniProtKB: I3MNF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131701   ⟸   XM_040275767
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040131702   ⟸   XM_040275768
- Peptide Label: isoform X5
RefSeq Acc Id: ENSSTOP00000013191   ⟸   ENSSTOT00000014726
RefSeq Acc Id: ENSSTOP00000026739   ⟸   ENSSTOT00000040052
Protein Domains
Ras-associating   SH2   VPS9


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014712 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014726.3 UniProtKB/TrEMBL
  ENSSTOT00000040052.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.80 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro RA_dom UniProtKB/TrEMBL
  RIN2_SH2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
  Vps9-like UniProtKB/TrEMBL
  VPS9_dom_sf UniProtKB/TrEMBL
NCBI Gene Rin2 ENTREZGENE
PANTHER PTHR23101 UniProtKB/TrEMBL
  RAS AND RAB INTERACTOR 2 UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
PROSITE PS50200 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
Superfamily-SCOP SSF109993 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt I3MNF9 ENTREZGENE, UniProtKB/TrEMBL