Dlst (dihydrolipoamide S-succinyltransferase) - Rat Genome Database

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Gene: Dlst (dihydrolipoamide S-succinyltransferase) Ictidomys tridecemlineatus
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Symbol: Dlst
Name: dihydrolipoamide S-succinyltransferase
RGD ID: 12452131
Description: ENCODES a protein that exhibits chaperone binding (ortholog); dihydrolipoyllysine-residue succinyltransferase activity (ortholog); heat shock protein binding (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (ortholog); NADH metabolic process (ortholog); succinyl-CoA metabolic process (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; citric acid cycle pathway; fumaric aciduria pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); intellectual disability (ortholog); Paragangliomas 7 (ortholog); FOUND IN centriolar satellite (ortholog); intracellular membrane-bounded organelle (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,007,904 - 28,030,206 (-)NCBI
SpeTri2.0NW_0049364884,038,985 - 4,061,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Dlst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,007,904 - 28,030,206 (-)NCBI
SpeTri2.0NW_0049364884,038,985 - 4,061,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381474,881,916 - 74,903,743 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1474,881,891 - 74,903,743 (+)EnsemblGRCh38hg38GRCh38
GRCh371475,348,619 - 75,370,446 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361474,418,372 - 74,440,199 (+)NCBINCBI36hg18NCBI36
Build 341474,418,371 - 74,440,196NCBI
Celera1455,386,967 - 55,408,821 (+)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1455,516,596 - 55,538,452 (+)NCBIHuRef
CHM1_11475,287,750 - 75,309,620 (+)NCBICHM1_1
T2T-CHM13v2.01469,091,016 - 69,112,843 (+)NCBI
Dlst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391285,157,597 - 85,180,865 (+)NCBIGRCm39mm39
GRCm39 Ensembl1285,157,607 - 85,181,619 (+)Ensembl
GRCm381285,110,822 - 85,134,091 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1285,110,833 - 85,134,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv371286,451,783 - 86,475,041 (+)NCBIGRCm37mm9NCBIm37
MGSCv361285,999,999 - 86,023,189 (+)NCBImm8
Celera1286,568,081 - 86,591,232 (+)NCBICelera
Cytogenetic Map12D1NCBI
Dlst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26104,758,511 - 104,783,296 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl6104,758,631 - 104,783,296 (+)Ensembl
Rnor_6.06108,936,534 - 108,961,322 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,936,664 - 108,959,803 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06116,595,654 - 116,620,427 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,156,751 - 109,180,537 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16109,160,220 - 109,183,992 (+)NCBI
Celera6102,581,378 - 102,605,253 (+)NCBICelera
Cytogenetic Map6q31NCBI
Dlst
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955523661,738 - 680,802 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955523660,413 - 680,878 (-)NCBIChiLan1.0ChiLan1.0
DLST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11474,278,128 - 74,300,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1474,278,128 - 74,300,133 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01455,433,358 - 55,455,876 (+)NCBIMhudiblu_PPA_v0panPan3
DLST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1848,003,730 - 48,025,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl848,002,211 - 48,024,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha847,687,937 - 47,709,198 (+)NCBI
ROS_Cfam_1.0848,231,361 - 48,252,635 (+)NCBI
ROS_Cfam_1.0 Ensembl848,230,731 - 48,252,633 (+)Ensembl
UMICH_Zoey_3.1847,902,283 - 47,923,535 (+)NCBI
UNSW_CanFamBas_1.0847,923,602 - 47,944,852 (+)NCBI
UU_Cfam_GSD_1.0848,321,863 - 48,343,131 (+)NCBI
DLST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl798,091,123 - 98,111,572 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1798,091,161 - 98,111,267 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,935,074 - 103,955,180 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12452,098,270 - 52,121,560 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605340,330,079 - 40,352,940 (+)NCBIVero_WHO_p1.0
Dlst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473426,803,344 - 26,825,272 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473426,802,902 - 26,824,632 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005321240   ⟹   XP_005321297
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864028,007,904 - 28,029,993 (-)NCBI
SpeTri2.0NW_0049364884,038,985 - 4,061,071 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040275791   ⟹   XP_040131725
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864028,007,904 - 28,030,206 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005321297 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131725 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3260688 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005321297   ⟸   XM_005321240
- Peptide Label: isoform X2
- UniProtKB: I3MN85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131725   ⟸   XM_040275791
- Peptide Label: isoform X1
Protein Domains
Lipoyl-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014603 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013084 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014606 UniProtKB/TrEMBL
Gene3D-CATH 3.30.559.10 UniProtKB/TrEMBL
InterPro 2-oxoA_DH_lipoyl-BS UniProtKB/TrEMBL
  2-oxoacid_DH_actylTfrase UniProtKB/TrEMBL
  Biotin_lipoyl UniProtKB/TrEMBL
  CAT-like_dom_sf UniProtKB/TrEMBL
  Single_hybrid_motif UniProtKB/TrEMBL
  SucB UniProtKB/TrEMBL
NCBI Gene Dlst ENTREZGENE
Pfam 2-oxoacid_dh UniProtKB/TrEMBL
  Biotin_lipoyl UniProtKB/TrEMBL
PROSITE BIOTINYL_LIPOYL UniProtKB/TrEMBL
  LIPOYL UniProtKB/TrEMBL
Superfamily-SCOP SSF51230 UniProtKB/TrEMBL
TIGRFAMs sucB UniProtKB/TrEMBL
UniProt I3MN85 ENTREZGENE, UniProtKB/TrEMBL