Cdk5rap1 (CDK5 regulatory subunit associated protein 1)

Gene: Cdk5rap1 (CDK5 regulatory subunit associated protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Cdk5rap1

Name:

CDK5 regulatory subunit associated protein 1

RGD ID:

12452066

Description:

ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN mitochondrial tRNA modification (ortholog); positive regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); positive regulation of mitochondrial translation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

CDK5 regulatory subunit associated protein 1, transcript variant X1; CDK5 regulatory subunit associated protein 1, transcript variant X2; CDK5 regulatory subunit associated protein 1, transcript variant X3; CDK5 regulatory subunit associated protein 1, transcript variant X4; CDK5 regulatory subunit-associated protein 1; mitochondrial tRNA methylthiotransferase CDK5RAP1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	171,575,109 - 171,607,082 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	7,142,478 - 7,176,262 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	7,142,528 - 7,174,435 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial tRNA modification (IEA,ISO)

positive regulation of cyclin-dependent protein serine/threonine kinase activity (ISO)

positive regulation of mitochondrial translation (IEA,ISO)

positive regulation of translational fidelity (IEA,ISO)

tRNA methylthiolation (IEA,ISO)

tRNA modification (IEA)

Cellular Component

cytosol (IEA)

mitochondrion (IEA)

nucleoplasm (IEA)

Molecular Function

4 iron, 4 sulfur cluster binding (IEA)

metal ion binding (IEA)

methylthiotransferase activity (IEA)

N6-isopentenyladenosine methylthiotransferase activity (IEA)

protein-containing complex binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cdk5rap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	171,575,109 - 171,607,082 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	7,142,478 - 7,176,262 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	7,142,528 - 7,174,435 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK5RAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	33,358,839 - 33,401,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	33,358,839 - 33,401,561 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	31,946,645 - 31,989,375 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	31,410,306 - 31,452,998 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	28,700,397 - 28,743,101 (-)	NCBI		Celera
Cytogenetic Map	20	q11.21	NCBI
HuRef	20	28,734,002 - 28,776,702 (-)	NCBI		HuRef
CHM1_1	20	31,847,728 - 31,890,453 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	35,086,043 - 35,128,797 (-)	NCBI		T2T-CHM13v2.0

Cdk5rap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	154,063,931 - 154,216,170 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	154,177,300 - 154,214,930 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	154,222,011 - 154,373,038 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	154,335,380 - 154,373,010 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	154,161,122 - 154,198,455 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	154,026,827 - 154,064,160 (-)	NCBI		MGSCv36	mm8
Celera	2	160,245,246 - 160,276,980 (-)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	76.46	NCBI

Cdk5rap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	163,189,435 - 163,333,003 (-)	NCBI		GRCr8
mRatBN7.2	3	142,838,081 - 142,872,669 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	142,708,028 - 142,872,677 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	146,703,769 - 146,740,020 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	155,321,928 - 155,358,184 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	153,061,296 - 153,097,549 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	149,835,953 - 149,870,429 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	149,703,848 - 149,870,413 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	156,207,918 - 156,241,596 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	144,803,213 - 144,840,056 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	144,542,380 - 144,745,686 (-)	NCBI
Celera	3	141,573,777 - 141,607,994 (-)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Cdk5rap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	27,879,389 - 27,906,861 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	27,878,048 - 27,907,157 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDK5RAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	39,051,655 - 39,097,406 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	39,044,755 - 39,090,499 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	29,648,003 - 29,690,210 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	30,762,967 - 30,804,237 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	30,762,967 - 30,804,237 (-)	Ensembl	panpan1.1		panPan2

CDK5RAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	22,588,354 - 22,628,525 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	22,588,354 - 22,628,450 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	22,233,958 - 22,273,952 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	23,274,345 - 23,314,508 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	23,274,346 - 23,314,461 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	22,549,684 - 22,589,773 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	22,660,263 - 22,700,448 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	23,091,600 - 23,131,993 (-)	NCBI		UU_Cfam_GSD_1.0

CDK5RAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	36,877,650 - 36,908,019 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	36,877,570 - 36,911,344 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	41,827,904 - 41,861,614 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK5RAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	37,655,094 - 37,695,129 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	37,655,102 - 37,695,075 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	89,202,342 - 89,243,001 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk5rap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624842	5,834,709 - 5,887,254 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005329924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013360581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013360582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021729584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000005495 ⟹ ENSSTOP00000004917

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936561	7,142,478 - 7,176,262 (+)	Ensembl

RefSeq Acc Id:

XM_005329924 ⟹ XP_005329981

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	171,575,109 - 171,607,053 (-)	NCBI
SpeTri2.0	NW_004936561	7,142,528 - 7,174,435 (+)	NCBI

Sequence:

show sequence

CGGCGGACAGCTGAGTGGAGGACCGCACCGCCTGGCGGAGCTTCCGCTGAAGGACACTAGATCC
GGCGGCTAGTGGAGGTGAGCGGCGGTCGCCGAGGGCTCGACTCTGGGCTGTTCAGTGCCATGCA
TCCTTTACAATGCATTCTTCGAGTACAGAGGTCTCTAAGGTGGGAACCGTTGACCTCTGTGTCC
TGGCTCTTGTTCAAGACCTGTAAGGCACACAGCACTCTCCCCAGCACTGCATGCCCCAGTCCAG
GCCAGCAGGAGGATGGAGTTCACAAGGATTTCAGCTCTAGGTTGGCCACTGGACCGACTTTTCA
GCATTTTTTAAGAGCTTCAGCTCCTCAAGAGAAACCATCCTCCCCAGAAGCAGAGGACCCACCC
CCCTATCTCACAGTGGATGAACTTCTAGGAAGGCAGAGAAAAGTCTATCTTGAGACCTATGGCT
GCCAGATGAATGTGAATGATACAGAGATAGCCTGGTCCATCTTACAGAAGAGTGGCTACCTGCG
GACCAGTAACCTCCAAGAGGCTGATGTGATTCTTCTTGTCACTTGTTCTATCAGGGAGAAGGCT
GAACAGACCATCTGGAACCGTTTACATCAGCTTAAAGCTTTGAAGACAAAACGATCCCGCTCCC
GGGTGCCTCTGAGGATTGGGATTCTAGGCTGCATGGCTGAGAGACTGAAGGAGGAGATCCTCAA
CAAGGAGAAAATGGTGGATCTCTTGGCTGGTCCGGATGCCTATCGAGACCTTCCCCGACTGCTG
GCTGTTGCGGAGTCAGGGCAACAAGCTGCCAATGTGCTGCTGTCTTTGGAGGAGACCTATGCTG
ATGTCATGCCAGTCCAGACAAACCCCAGTGCCACCTCTGCCTTCGTGTCAATAATGCGGGGCTG
TGACAACATGTGCAGCTATTGCATTGTTCCGTTCACACGTGGTAGGGAAAGGAGTCGGCCTATA
GCCTCCATTCTGGAGGAGGTGAGGAAGCTTTCTGAGCAGGGGCTAAAAGAAGTGACTCTTCTTG
GTCAGAATGTTAATAGTTTTCGGGACAATTCCGAGATCCAGTTCAACAGTGCAGTGCCTACCAA
CCTCAGCCGAGGCTTTACCACCAACTATAAAACCAAACAAGGCGGGCTTCGTTTTTCTCACCTT
CTGGATCAGGTTTCCAGAGTAGATCCTGAAATGAGGATCCGTTTCACTTCTCCCCACCCCAAGG
ATTTTCCTGATGAGGTTCTGCAGCTGATTCACGAAAGAGGCAACATCTGTAAGCAGATCCACCT
GCCTGCCCAGAGTGGAAGCAGTCGTGTGCTGGATGCCATGCGGAGGGGATATTCAAGAGAAGCT
TATGTGGAGTTAGTTCACCATATCAGAGAATCTATCCCAGGTGTGAGCCTCAGCAGCGATTTCA
TTGCTGGCTTTTGCGGGGAGACAGAGGAAGACCACCTGCAGACAGTGTCTTTGCTTCGGGAAGT
TCAGTACAACATGGGTTTCCTCTTTGCCTACAGCATGAGACAGAAGACACGGGCTTATCATAGG
CTGAAGGATGACGTCCCAGAAGAAGTAAAATTAAGGCGTTTGGAGGAACTTATCACTGTTTTCC
GAGAAGAAGCTTCAAAAGCCAATGGGACCTGTGTGGGCAGTACCCAGCTGGTACTGGTAGAAGG
GCCCAGCAAACGCTCTGCCACTGACCTGTGTGGCCGGAATGATGGAAATCTTAAGGTGATCTTT
CCTGATGCAGAGATGGAGGACACTGCTAACCCTGGGCTCAGGGTCAGAGCACAGCCTGGGGACT
ATGTGCTAGTGAAGATCACCTCTGCCAGCTCTCAGACACTTAAAGGACATGTCCTCTGTAGGAC
CACTCTGAAGGACTCCTTGGCACATTGCTGACCTGAGGGGATGGGCTCAGCATTGAGTTGGGCC
ATCCTTCTCTACAGGAAGGACAACATGACTGGTCACTAATGAAAGCGGTAATGAAGCTTCAGAG
ACAGGAGCGAGTGGTAAAGTGACTGTGTCTAATGGAAGCCTCATCTCCTTGTGCTGCATGAACC
CTTGATAGTCATTAAATTTACCTGAAACGAATGGACATACTTTTA

hide sequence

RefSeq Acc Id:

XM_013360581 ⟹ XP_013216035

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	171,575,109 - 171,606,819 (-)	NCBI
SpeTri2.0	NW_004936561	7,142,693 - 7,174,435 (+)	NCBI

Sequence:

show sequence

AGTGGCTGAGGCGCGGGGCCTGGAGTCTGGGGTTCGTGCCCAGCCCCGCTGCGTACTCCCGTGT
GACCTTGGGCAAGTCACCCCACTTCTTCTGAGCACTAGCTTCGTCACCTGTGAAATGGGGATGA
TACAACGAGCCTCACAGAGTTGCTACTCTGGGCTGTTCAGTGCCATGCATCCTTTACAATGCAT
TCTTCGAGTACAGAGGTCTCTAAGGTGGGAACCGTTGACCTCTGTGTCCTGGCTCTTGTTCAAG
ACCTGTAAGGCACACAGCACTCTCCCCAGCACTGCATGCCCCAGTCCAGGCCAGCAGGAGGATG
GAGTTCACAAGGATTTCAGCTCTAGGTTGGCCACTGGACCGACTTTTCAGCATTTTTTAAGAGC
TTCAGCTCCTCAAGAGAAACCATCCTCCCCAGAAGCAGAGGACCCACCCCCCTATCTCACAGTG
GATGAACTTCTAGGAAGGCAGAGAAAAGTCTATCTTGAGACCTATGGCTGCCAGATGAATGTGA
ATGATACAGAGATAGCCTGGTCCATCTTACAGAAGAGTGGCTACCTGCGGACCAGTAACCTCCA
AGAGGCTGATGTGATTCTTCTTGTCACTTGTTCTATCAGGGAGAAGGCTGAACAGACCATCTGG
AACCGTTTACATCAGCTTAAAGCTTTGAAGACAAAACGATCCCGCTCCCGGGTGCCTCTGAGGA
TTGGGATTCTAGGCTGCATGGCTGAGAGACTGAAGGAGGAGATCCTCAACAAGGAGAAAATGGT
GGATCTCTTGGCTGGTCCGGATGCCTATCGAGACCTTCCCCGACTGCTGGCTGTTGCGGAGTCA
GGGCAACAAGCTGCCAATGTGCTGCTGTCTTTGGAGGAGACCTATGCTGATGTCATGCCAGTCC
AGACAAACCCCAGTGCCACCTCTGCCTTCGTGTCAATAATGCGGGGCTGTGACAACATGTGCAG
CTATTGCATTGTTCCGTTCACACGTGGTAGGGAAAGGAGTCGGCCTATAGCCTCCATTCTGGAG
GAGGTGAGGAAGCTTTCTGAGCAGGGGCTAAAAGAAGTGACTCTTCTTGGTCAGAATGTTAATA
GTTTTCGGGACAATTCCGAGATCCAGTTCAACAGTGCAGTGCCTACCAACCTCAGCCGAGGCTT
TACCACCAACTATAAAACCAAACAAGGCGGGCTTCGTTTTTCTCACCTTCTGGATCAGGTTTCC
AGAGTAGATCCTGAAATGAGGATCCGTTTCACTTCTCCCCACCCCAAGGATTTTCCTGATGAGG
TTCTGCAGCTGATTCACGAAAGAGGCAACATCTGTAAGCAGATCCACCTGCCTGCCCAGAGTGG
AAGCAGTCGTGTGCTGGATGCCATGCGGAGGGGATATTCAAGAGAAGCTTATGTGGAGTTAGTT
CACCATATCAGAGAATCTATCCCAGGTGTGAGCCTCAGCAGCGATTTCATTGCTGGCTTTTGCG
GGGAGACAGAGGAAGACCACCTGCAGACAGTGTCTTTGCTTCGGGAAGTTCAGTACAACATGGG
TTTCCTCTTTGCCTACAGCATGAGACAGAAGACACGGGCTTATCATAGGCTGAAGGATGACGTC
CCAGAAGAAGTAAAATTAAGGCGTTTGGAGGAACTTATCACTGTTTTCCGAGAAGAAGCTTCAA
AAGCCAATGGGACCTGTGTGGGCAGTACCCAGCTGGTACTGGTAGAAGGGCCCAGCAAACGCTC
TGCCACTGACCTGTGTGGCCGGAATGATGGAAATCTTAAGGTGATCTTTCCTGATGCAGAGATG
GAGGACACTGCTAACCCTGGGCTCAGGGTCAGAGCACAGCCTGGGGACTATGTGCTAGTGAAGA
TCACCTCTGCCAGCTCTCAGACACTTAAAGGACATGTCCTCTGTAGGACCACTCTGAAGGACTC
CTTGGCACATTGCTGACCTGAGGGGATGGGCTCAGCATTGAGTTGGGCCATCCTTCTCTACAGG
AAGGACAACATGACTGGTCACTAATGAAAGCGGTAATGAAGCTTCAGAGACAGGAGCGAGTGGT
AAAGTGACTGTGTCTAATGGAAGCCTCATCTCCTTGTGCTGCATGAACCCTTGATAGTCATTAA
ATTTACCTGAAACGAATGGACATACTTTTA

hide sequence

RefSeq Acc Id:

XM_013360582 ⟹ XP_013216036

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	171,575,109 - 171,607,082 (-)	NCBI
SpeTri2.0	NW_004936561	7,142,548 - 7,174,435 (+)	NCBI

Sequence:

show sequence

GACCGCACCGCCTGGCGGAGCTTCCGCTGAAGGACACTAGATCCGGCGGCTAGTGGAGACTCTG
GGCTGTTCAGTGCCATGCATCCTTTACAATGCATTCTTCGAGTACAGAGGTCTCTAAGGTGGGA
ACCGTTGACCTCTGTGTCCTGGCTCTTGTTCAAGACCTGTAAGGCACACAGCACTCTCCCCAGC
ACTGCATGCCCCAGTCCAGGCCAGCAGGAGGATGGAGTTCACAAGGATTTCAGCTCTAGGTTGG
CCACTGGACCGACTTTTCAGCATTTTTTAAGAGCTTCAGCTCCTCAAGAGAAACCATCCTCCCC
AGAAGCAGAGGACCCACCCCCCTATCTCACAGTGGATGAACTTCTAGGAAGGCAGAGAAAAGTC
TATCTTGAGACCTATGGCTGCCAGATGAATGTGAATGATACAGAGATAGCCTGGTCCATCTTAC
AGAAGAGTGGCTACCTGCGGACCAGTAACCTCCAAGAGGCTGATGTGATTCTTCTTGTCACTTG
TTCTATCAGGGAGAAGGCTGAACAGACCATCTGGAACCGTTTACATCAGCTTAAAGCTTTGAAG
ACAAAACGATCCCGCTCCCGGGTGCCTCTGAGGATTGGGATTCTAGGCTGCATGGCTGAGAGAC
TGAAGGAGGAGATCCTCAACAAGGAGAAAATGGTGGATCTCTTGGCTGGTCCGGATGCCTATCG
AGACCTTCCCCGACTGCTGGCTGTTGCGGAGTCAGGGCAACAAGCTGCCAATGTGCTGCTGTCT
TTGGAGGAGACCTATGCTGATGTCATGCCAGTCCAGACAAACCCCAGTGCCACCTCTGCCTTCG
TGTCAATAATGCGGGGCTGTGACAACATGTGCAGCTATTGCATTGTTCCGTTCACACGTGGTAG
GGAAAGGAGTCGGCCTATAGCCTCCATTCTGGAGGAGGTGAGGAAGCTTTCTGAGCAGGGGCTA
AAAGAAGTGACTCTTCTTGGTCAGAATGTTAATAGTTTTCGGGACAATTCCGAGATCCAGTTCA
ACAGTGCAGTGCCTACCAACCTCAGCCGAGGCTTTACCACCAACTATAAAACCAAACAAGGCGG
GCTTCGTTTTTCTCACCTTCTGGATCAGGTTTCCAGAGTAGATCCTGAAATGAGGATCCGTTTC
ACTTCTCCCCACCCCAAGGATTTTCCTGATGAGGTTCTGCAGCTGATTCACGAAAGAGGCAACA
TCTGTAAGCAGATCCACCTGCCTGCCCAGAGTGGAAGCAGTCGTGTGCTGGATGCCATGCGGAG
GGGATATTCAAGAGAAGCTTATGTGGAGTTAGTTCACCATATCAGAGAATCTATCCCAGGTGTG
AGCCTCAGCAGCGATTTCATTGCTGGCTTTTGCGGGGAGACAGAGGAAGACCACCTGCAGACAG
TGTCTTTGCTTCGGGAAGTTCAGTACAACATGGGTTTCCTCTTTGCCTACAGCATGAGACAGAA
GACACGGGCTTATCATAGGCTGAAGGATGACGTCCCAGAAGAAGTAAAATTAAGGCGTTTGGAG
GAACTTATCACTGTTTTCCGAGAAGAAGCTTCAAAAGCCAATGGGACCTGTGTGGGCAGTACCC
AGCTGGTACTGGTAGAAGGGCCCAGCAAACGCTCTGCCACTGACCTGTGTGGCCGGAATGATGG
AAATCTTAAGGTGATCTTTCCTGATGCAGAGATGGAGGACACTGCTAACCCTGGGCTCAGGGTC
AGAGCACAGCCTGGGGACTATGTGCTAGTGAAGATCACCTCTGCCAGCTCTCAGACACTTAAAG
GACATGTCCTCTGTAGGACCACTCTGAAGGACTCCTTGGCACATTGCTGACCTGAGGGGATGGG
CTCAGCATTGAGTTGGGCCATCCTTCTCTACAGGAAGGACAACATGACTGGTCACTAATGAAAG
CGGTAATGAAGCTTCAGAGACAGGAGCGAGTGGTAAAGTGACTGTGTCTAATGGAAGCCTCATC
TCCTTGTGCTGCATGAACCCTTGATAGTCATTAAATTTACCTGAAACGAATGGACATACTTTTA

hide sequence

RefSeq Acc Id:

XM_021729584 ⟹ XP_021585259

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	171,575,109 - 171,605,212 (-)	NCBI
SpeTri2.0	NW_004936561	7,144,257 - 7,174,435 (+)	NCBI

Sequence:

show sequence

CTACACTCCCACCCATGTGAATGAGTCTCGTGATGGAGAGTTAGAAGAGAACTTTGGGAACTCA
GAAGAGGATCCCAGCCTAAATTGGGGATGGTGGCCAGGACTCTGGGCTGTTCAGTGCCATGCAT
CCTTTACAATGCATTCTTCGAGTACAGAGGTCTCTAAGGTGGGAACCGTTGACCTCTGTGTCCT
GGCTCTTGTTCAAGACCTGTAAGGCACACAGCACTCTCCCCAGCACTGCATGCCCCAGTCCAGG
CCAGCAGGAGGATGGAGTTCACAAGGATTTCAGCTCTAGGTTGGCCACTGGACCGACTTTTCAG
CATTTTTTAAGAGCTTCAGCTCCTCAAGAGAAACCATCCTCCCCAGAAGCAGAGGACCCACCCC
CCTATCTCACAGTGGATGAACTTCTAGGAAGGCAGAGAAAAGTCTATCTTGAGACCTATGGCTG
CCAGATGAATGTGAATGATACAGAGATAGCCTGGTCCATCTTACAGAAGAGTGGCTACCTGCGG
ACCAGTAACCTCCAAGAGGCTGATGTGATTCTTCTTGTCACTTGTTCTATCAGGGAGAAGGCTG
AACAGACCATCTGGAACCGTTTACATCAGCTTAAAGCTTTGAAGACAAAACGATCCCGCTCCCG
GGTGCCTCTGAGGATTGGGATTCTAGGCTGCATGGCTGAGAGACTGAAGGAGGAGATCCTCAAC
AAGGAGAAAATGGTGGATCTCTTGGCTGGTCCGGATGCCTATCGAGACCTTCCCCGACTGCTGG
CTGTTGCGGAGTCAGGGCAACAAGCTGCCAATGTGCTGCTGTCTTTGGAGGAGACCTATGCTGA
TGTCATGCCAGTCCAGACAAACCCCAGTGCCACCTCTGCCTTCGTGTCAATAATGCGGGGCTGT
GACAACATGTGCAGCTATTGCATTGTTCCGTTCACACGTGGTAGGGAAAGGAGTCGGCCTATAG
CCTCCATTCTGGAGGAGGTGAGGAAGCTTTCTGAGCAGGGGCTAAAAGAAGTGACTCTTCTTGG
TCAGAATGTTAATAGTTTTCGGGACAATTCCGAGATCCAGTTCAACAGTGCAGTGCCTACCAAC
CTCAGCCGAGGCTTTACCACCAACTATAAAACCAAACAAGGCGGGCTTCGTTTTTCTCACCTTC
TGGATCAGGTTTCCAGAGTAGATCCTGAAATGAGGATCCGTTTCACTTCTCCCCACCCCAAGGA
TTTTCCTGATGAGGTTCTGCAGCTGATTCACGAAAGAGGCAACATCTGTAAGCAGATCCACCTG
CCTGCCCAGAGTGGAAGCAGTCGTGTGCTGGATGCCATGCGGAGGGGATATTCAAGAGAAGCTT
ATGTGGAGTTAGTTCACCATATCAGAGAATCTATCCCAGGTGTGAGCCTCAGCAGCGATTTCAT
TGCTGGCTTTTGCGGGGAGACAGAGGAAGACCACCTGCAGACAGTGTCTTTGCTTCGGGAAGTT
CAGTACAACATGGGTTTCCTCTTTGCCTACAGCATGAGACAGAAGACACGGGCTTATCATAGGC
TGAAGGATGACGTCCCAGAAGAAGTAAAATTAAGGCGTTTGGAGGAACTTATCACTGTTTTCCG
AGAAGAAGCTTCAAAAGCCAATGGGACCTGTGTGGGCAGTACCCAGCTGGTACTGGTAGAAGGG
CCCAGCAAACGCTCTGCCACTGACCTGTGTGGCCGGAATGATGGAAATCTTAAGGTGATCTTTC
CTGATGCAGAGATGGAGGACACTGCTAACCCTGGGCTCAGGGTCAGAGCACAGCCTGGGGACTA
TGTGCTAGTGAAGATCACCTCTGCCAGCTCTCAGACACTTAAAGGACATGTCCTCTGTAGGACC
ACTCTGAAGGACTCCTTGGCACATTGCTGACCTGAGGGGATGGGCTCAGCATTGAGTTGGGCCA
TCCTTCTCTACAGGAAGGACAACATGACTGGTCACTAATGAAAGCGGTAATGAAGCTTCAGAGA
CAGGAGCGAGTGGTAAAGTGACTGTGTCTAATGGAAGCCTCATCTCCTTGTGCTGCATGAACCC
TTGATAGTCATTAAATTTACCTGAAACGAATGGACATACTTTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005329981	(Get FASTA)	NCBI Sequence Viewer
	XP_013216035	(Get FASTA)	NCBI Sequence Viewer
	XP_013216036	(Get FASTA)	NCBI Sequence Viewer
	XP_021585259	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000004917.3
GenBank Protein	KAG3263094	(Get FASTA)	NCBI Sequence Viewer
	KAG3263095	(Get FASTA)	NCBI Sequence Viewer
	KAG3263096	(Get FASTA)	NCBI Sequence Viewer
	KAG3263097	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005329981 ⟸ XM_005329924
- Peptide Label:	isoform X2
- UniProtKB:	I3M665 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHPLQCILRVQRSLRWEPLTSVSWLLFKTCKAHSTLPSTACPSPGQQEDGVHKDFSSRLATGPT FQHFLRASAPQEKPSSPEAEDPPPYLTVDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGY LRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTKRSRSRVPLRIGILGCMAERLKEEI LNKEKMVDLLAGPDAYRDLPRLLAVAESGQQAANVLLSLEETYADVMPVQTNPSATSAFVSIMR GCDNMCSYCIVPFTRGRERSRPIASILEEVRKLSEQGLKEVTLLGQNVNSFRDNSEIQFNSAVP TNLSRGFTTNYKTKQGGLRFSHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERGNICKQI HLPAQSGSSRVLDAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHLQTVSLLR EVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKANGTCVGSTQLVLV EGPSKRSATDLCGRNDGNLKVIFPDAEMEDTANPGLRVRAQPGDYVLVKITSASSQTLKGHVLC RTTLKDSLAHC hide sequence

RefSeq Acc Id:	XP_013216036 ⟸ XM_013360582
- Peptide Label:	isoform X2
- UniProtKB:	I3M665 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHPLQCILRVQRSLRWEPLTSVSWLLFKTCKAHSTLPSTACPSPGQQEDGVHKDFSSRLATGPT FQHFLRASAPQEKPSSPEAEDPPPYLTVDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGY LRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTKRSRSRVPLRIGILGCMAERLKEEI LNKEKMVDLLAGPDAYRDLPRLLAVAESGQQAANVLLSLEETYADVMPVQTNPSATSAFVSIMR GCDNMCSYCIVPFTRGRERSRPIASILEEVRKLSEQGLKEVTLLGQNVNSFRDNSEIQFNSAVP TNLSRGFTTNYKTKQGGLRFSHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERGNICKQI HLPAQSGSSRVLDAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHLQTVSLLR EVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKANGTCVGSTQLVLV EGPSKRSATDLCGRNDGNLKVIFPDAEMEDTANPGLRVRAQPGDYVLVKITSASSQTLKGHVLC RTTLKDSLAHC hide sequence

RefSeq Acc Id:

XP_013216035 ⟸ XM_013360581

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGMIQRASQSCYSGLFSAMHPLQCILRVQRSLRWEPLTSVSWLLFKTCKAHSTLPSTACPSPGQ
QEDGVHKDFSSRLATGPTFQHFLRASAPQEKPSSPEAEDPPPYLTVDELLGRQRKVYLETYGCQ
MNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTKRSRSRV
PLRIGILGCMAERLKEEILNKEKMVDLLAGPDAYRDLPRLLAVAESGQQAANVLLSLEETYADV
MPVQTNPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVRKLSEQGLKEVTLLGQ
NVNSFRDNSEIQFNSAVPTNLSRGFTTNYKTKQGGLRFSHLLDQVSRVDPEMRIRFTSPHPKDF
PDEVLQLIHERGNICKQIHLPAQSGSSRVLDAMRRGYSREAYVELVHHIRESIPGVSLSSDFIA
GFCGETEEDHLQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFRE
EASKANGTCVGSTQLVLVEGPSKRSATDLCGRNDGNLKVIFPDAEMEDTANPGLRVRAQPGDYV
LVKITSASSQTLKGHVLCRTTLKDSLAHC

hide sequence

RefSeq Acc Id:	XP_021585259 ⟸ XM_021729584
- Peptide Label:	isoform X2
- UniProtKB:	I3M665 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHPLQCILRVQRSLRWEPLTSVSWLLFKTCKAHSTLPSTACPSPGQQEDGVHKDFSSRLATGPT FQHFLRASAPQEKPSSPEAEDPPPYLTVDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGY LRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTKRSRSRVPLRIGILGCMAERLKEEI LNKEKMVDLLAGPDAYRDLPRLLAVAESGQQAANVLLSLEETYADVMPVQTNPSATSAFVSIMR GCDNMCSYCIVPFTRGRERSRPIASILEEVRKLSEQGLKEVTLLGQNVNSFRDNSEIQFNSAVP TNLSRGFTTNYKTKQGGLRFSHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERGNICKQI HLPAQSGSSRVLDAMRRGYSREAYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHLQTVSLLR EVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKANGTCVGSTQLVLV EGPSKRSATDLCGRNDGNLKVIFPDAEMEDTANPGLRVRAQPGDYVLVKITSASSQTLKGHVLC RTTLKDSLAHC hide sequence

RefSeq Acc Id:

ENSSTOP00000004917 ⟸ ENSSTOT00000005495

Protein Domains

MTTase N-terminal Radical SAM core TRAM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000005492	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000005495.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.12160	UniProtKB/TrEMBL
	3.80.30.20	UniProtKB/TrEMBL
InterPro	Elp3/MiaB/NifB	UniProtKB/TrEMBL
	Methylthiotransferase	UniProtKB/TrEMBL
	Methylthiotransferase_CS	UniProtKB/TrEMBL
	Methylthiotransferase_N	UniProtKB/TrEMBL
	Methylthiotransferase_N_sf	UniProtKB/TrEMBL
	MiaB_methiolase	UniProtKB/TrEMBL
	rSAM	UniProtKB/TrEMBL
	rSAM_horseshoe	UniProtKB/TrEMBL
	TRAM_dom	UniProtKB/TrEMBL
NCBI Gene	Cdk5rap1	ENTREZGENE
PANTHER	CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1	UniProtKB/TrEMBL
	MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1	UniProtKB/TrEMBL
Pfam	Radical_SAM	UniProtKB/TrEMBL
	TRAM	UniProtKB/TrEMBL
	UPF0004	UniProtKB/TrEMBL
PROSITE	MTTASE_N	UniProtKB/TrEMBL
	MTTASE_RADICAL	UniProtKB/TrEMBL
	RADICAL_SAM	UniProtKB/TrEMBL
	TRAM	UniProtKB/TrEMBL
SMART	Elp3	UniProtKB/TrEMBL
Superfamily-SCOP	Radical SAM enzymes	UniProtKB/TrEMBL
UniProt	I3M665	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar