Piezo2 (piezo type mechanosensitive ion channel component 2) - Rat Genome Database

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Gene: Piezo2 (piezo type mechanosensitive ion channel component 2) Ictidomys tridecemlineatus
Analyze
Symbol: Piezo2
Name: piezo type mechanosensitive ion channel component 2
RGD ID: 12450591
Description: ENCODES a protein that exhibits monoatomic cation channel activity (ortholog); INVOLVED IN detection of mechanical stimulus involved in sensory perception (ortholog); monoatomic cation transport (ortholog); regulation of membrane potential (ortholog); ASSOCIATED WITH cerebral palsy (ortholog); chromosome 18p deletion syndrome (ortholog); Contracture (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: piezo-type mechanosensitive ion channel component 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049441,573,205 - 1,912,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936626802,490 - 1,140,082 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936626802,415 - 1,141,260 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Piezo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049441,573,205 - 1,912,950 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936626802,490 - 1,140,082 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936626802,415 - 1,141,260 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIEZO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381810,670,247 - 11,149,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1810,666,483 - 11,149,569 (-)EnsemblGRCh38hg38GRCh38
GRCh371810,670,244 - 11,149,568 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361810,660,850 - 10,687,814 (-)NCBINCBI36Build 36hg18NCBI36
Build 341810,660,859 - 10,687,814NCBI
Celera1810,552,160 - 11,030,879 (-)NCBICelera
Cytogenetic Map18p11.22-p11.21NCBI
HuRef1810,624,312 - 11,102,956 (-)NCBIHuRef
CHM1_11810,669,431 - 11,148,579 (-)NCBICHM1_1
T2T-CHM13v2.01810,832,368 - 11,311,713 (-)NCBIT2T-CHM13v2.0
Piezo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391863,143,284 - 63,520,787 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1863,143,284 - 63,520,254 (-)EnsemblGRCm39 Ensembl
GRCm381863,010,213 - 63,387,716 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1863,010,213 - 63,387,183 (-)EnsemblGRCm38mm10GRCm38
MGSCv371863,169,867 - 63,546,837 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361863,167,798 - 63,511,826 (-)NCBIMGSCv36mm8
Celera1864,286,871 - 64,658,106 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1835.95NCBI
Piezo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81858,738,734 - 59,115,252 (-)NCBIGRCr8
mRatBN7.21856,468,449 - 56,844,984 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1856,469,680 - 56,844,216 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01858,353,361 - 58,728,555 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1858,354,648 - 58,499,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01857,576,278 - 57,949,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41859,147,791 - 59,531,873 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11859,220,826 - 59,402,111 (-)NCBI
Celera1854,616,241 - 54,988,723 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Piezo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554021,650,726 - 1,871,876 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554021,534,619 - 1,873,143 (+)NCBIChiLan1.0ChiLan1.0
PIEZO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21727,304,996 - 27,783,714 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11812,997,591 - 13,476,294 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0183,141,285 - 3,619,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1185,407,467 - 5,884,207 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl185,407,467 - 5,882,928 (+)Ensemblpanpan1.1panPan2
PIEZO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1776,477,628 - 76,918,660 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl776,478,928 - 76,919,723 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha775,880,977 - 76,321,043 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0776,533,250 - 76,973,897 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl776,533,865 - 76,974,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1776,231,312 - 76,673,520 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0776,259,881 - 76,700,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0776,564,098 - 77,004,969 (-)NCBIUU_Cfam_GSD_1.0
PIEZO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl697,643,978 - 97,944,456 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1697,644,115 - 97,945,693 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PIEZO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11870,161,961 - 70,623,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1870,246,132 - 70,622,611 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605045,184,171 - 45,648,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Piezo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477018,836,899 - 19,157,114 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477018,835,706 - 19,157,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000026647   ⟹   ENSSTOP00000016774
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936626802,490 - 1,140,082 (+)Ensembl
RefSeq Acc Id: XM_040275296   ⟹   XP_040131230
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049441,573,205 - 1,912,950 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040131230 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000016774.2
GenBank Protein KAG3293497 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040131230   ⟸   XM_040275296
- UniProtKB: A0A5B8HPD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000016774   ⟸   ENSSTOT00000026647
Protein Domains
PIEZO   Piezo non-specific cation channel R-Ras-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025402 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026647.2 UniProtKB/TrEMBL
InterPro Piezo UniProtKB/TrEMBL
  Piezo_dom UniProtKB/TrEMBL
  Piezo_RRas-bd_dom UniProtKB/TrEMBL
NCBI Gene Piezo2 ENTREZGENE
PANTHER PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT UniProtKB/TrEMBL
  PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL HOMOLOG UniProtKB/TrEMBL
Pfam PIEZO UniProtKB/TrEMBL
  Piezo_RRas_bdg UniProtKB/TrEMBL
UniProt A0A5B8HPD8 ENTREZGENE, UniProtKB/TrEMBL
  I3MXC9_ICTTR UniProtKB/TrEMBL