Ganab (glucosidase II alpha subunit) - Rat Genome Database

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Gene: Ganab (glucosidase II alpha subunit) Ictidomys tridecemlineatus
Analyze
Symbol: Ganab
Name: glucosidase II alpha subunit
RGD ID: 12449098
Description: ENCODES a protein that exhibits alpha-glucosidase activity (inferred); carbohydrate binding (inferred); glucan 1,3-alpha-glucosidase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); N-glycan processing (inferred); ASSOCIATED WITH autosomal dominant polycystic kidney disease (ortholog); Chemical and Drug Induced Liver Injury (ortholog); chronic kidney disease (ortholog); FOUND IN glucosidase II complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glucosidase II alpha subunit, transcript variant X1; glucosidase II alpha subunit, transcript variant X2; neutral alpha-glucosidase AB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,499,450 - 10,519,253 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581613,253 - 634,130 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581613,292 - 633,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ganab
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,499,450 - 10,519,253 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581613,253 - 634,130 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936581613,292 - 633,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GANAB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,624,829 - 62,646,613 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,624,826 - 62,646,726 (-)EnsemblGRCh38hg38GRCh38
GRCh371162,392,301 - 62,414,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,148,874 - 62,170,680 (-)NCBINCBI36Build 36hg18NCBI36
Celera1159,721,867 - 59,743,650 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,721,213 - 58,743,094 (-)NCBIHuRef
CHM1_11162,275,360 - 62,297,261 (-)NCBICHM1_1
T2T-CHM13v2.01162,614,283 - 62,636,065 (-)NCBIT2T-CHM13v2.0
Ganab
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,875,440 - 8,894,098 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,875,435 - 8,894,036 (+)EnsemblGRCm39 Ensembl
GRCm38198,898,057 - 8,916,742 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,898,071 - 8,916,672 (+)EnsemblGRCm38mm10GRCm38
MGSCv37198,972,601 - 8,991,156 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36198,965,156 - 8,983,711 (+)NCBIMGSCv36mm8
Celera198,658,850 - 8,677,438 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.96NCBI
Ganab
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,222,918 - 215,242,808 (+)NCBIGRCr8
mRatBN7.21205,793,910 - 205,813,704 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,793,895 - 205,813,695 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1214,202,380 - 214,222,147 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,237,290 - 221,257,073 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,930,135 - 213,949,926 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,096,558 - 225,116,384 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,096,598 - 225,116,378 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,034,192 - 232,054,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,573,299 - 211,593,941 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,731,731 - 211,752,441 (+)NCBI
Celera1203,306,664 - 203,326,465 (+)NCBICelera
Cytogenetic Map1q43NCBI
Ganab
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599556,362 - 573,353 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955599556,510 - 569,891 (+)NCBIChiLan1.0ChiLan1.0
GANAB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,852,079 - 63,873,617 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,894,990 - 64,916,316 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,982,393 - 58,003,871 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,336,484 - 61,357,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,336,487 - 61,357,908 (-)Ensemblpanpan1.1panPan2
GANAB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,004,296 - 54,019,148 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,003,689 - 54,018,157 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,609,341 - 52,623,535 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,057,019 - 55,071,200 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,057,084 - 55,071,846 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,152,699 - 54,167,101 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,728,031 - 53,742,203 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,523,421 - 54,537,620 (+)NCBIUU_Cfam_GSD_1.0
GANAB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl29,100,702 - 9,118,390 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.129,100,672 - 9,118,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,446,419 - 8,463,996 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GANAB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,257,867 - 11,279,534 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,257,935 - 11,281,111 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038108,592,667 - 108,615,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ganab
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,146,886 - 1,160,876 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249261,147,470 - 1,160,901 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000002955   ⟹   ENSSTOP00000002643
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936581613,253 - 634,130 (+)Ensembl
RefSeq Acc Id: XM_005331494   ⟹   XP_005331551
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494710,499,450 - 10,519,253 (+)NCBI
SpeTri2.0NW_004936581613,292 - 633,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005331495   ⟹   XP_005331552
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494710,499,450 - 10,519,253 (+)NCBI
SpeTri2.0NW_004936581613,292 - 633,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040284217   ⟹   XP_040140151
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494710,508,889 - 10,519,253 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005331551 (Get FASTA)   NCBI Sequence Viewer  
  XP_005331552 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140151 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002643.2
GenBank Protein KAG3284864 (Get FASTA)   NCBI Sequence Viewer  
  KAG3284865 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005331551   ⟸   XM_005331494
- Peptide Label: isoform X1
- UniProtKB: I3M1F3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005331552   ⟸   XM_005331495
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040140151   ⟸   XM_040284217
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000002643   ⟸   ENSSTOT00000002955
Protein Domains
Glycoside hydrolase family 31 N-terminal   Glycoside hydrolase family 31 TIM barrel   Glycosyl hydrolase family 31 C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002934 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002955.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
  glycosyl hydrolase (family 31) UniProtKB/TrEMBL
InterPro Gal_mutarotase_sf_dom UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_AS UniProtKB/TrEMBL
  Glyco_hydro_31_C UniProtKB/TrEMBL
  Glyco_hydro_31_CS UniProtKB/TrEMBL
  Glyco_hydro_31_N_dom UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
NCBI Gene Ganab ENTREZGENE
PANTHER ALPHA-GLUCOSIDASE UniProtKB/TrEMBL
  NEUTRAL ALPHA-GLUCOSIDASE AB UniProtKB/TrEMBL
Pfam Gal_mutarotas_2 UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_3rd UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F31_1 UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F31_2 UniProtKB/TrEMBL
Superfamily-SCOP Glycosyl hydrolase domain UniProtKB/TrEMBL
  SSF51445 UniProtKB/TrEMBL
  SSF74650 UniProtKB/TrEMBL
UniProt I3M1F3 ENTREZGENE, UniProtKB/TrEMBL