Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3) - Rat Genome Database

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Gene: Arap3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3) Ictidomys tridecemlineatus
Analyze
Symbol: Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
RGD ID: 12448935
Description: ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN signal transduction (inferred); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, transcript variant X1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, transcript variant X2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,915,483 - 150,940,433 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650412,490,850 - 12,513,996 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650412,490,838 - 12,514,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Arap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,915,483 - 150,940,433 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650412,490,850 - 12,513,996 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650412,490,838 - 12,514,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385141,653,402 - 141,682,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5141,653,401 - 141,682,230 (-)EnsemblGRCh38hg38GRCh38
GRCh375141,032,969 - 141,061,797 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365141,013,152 - 141,041,984 (-)NCBINCBI36Build 36hg18NCBI36
Build 345141,013,153 - 141,041,984NCBI
Celera5137,109,696 - 137,138,526 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5136,177,475 - 136,206,231 (-)NCBIHuRef
CHM1_15140,466,257 - 140,495,264 (-)NCBICHM1_1
T2T-CHM13v2.05142,179,417 - 142,208,259 (-)NCBIT2T-CHM13v2.0
Arap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,105,676 - 38,132,583 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1838,105,681 - 38,132,022 (-)EnsemblGRCm39 Ensembl
GRCm381837,972,623 - 37,999,531 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1837,972,628 - 37,998,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,132,277 - 38,157,228 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361838,098,602 - 38,123,089 (-)NCBIMGSCv36mm8
Celera1839,316,005 - 39,340,938 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1819.85NCBI
Arap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81830,058,739 - 30,085,415 (-)NCBIGRCr8
mRatBN7.21829,806,214 - 29,834,217 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1829,807,536 - 29,833,555 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01831,112,083 - 31,138,142 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1831,112,623 - 31,136,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01830,800,119 - 30,825,636 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,893,720 - 30,916,965 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11830,920,906 - 30,943,620 (-)NCBI
Celera1829,452,116 - 29,478,222 (-)NCBICelera
Cytogenetic Map18p11NCBI
Arap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541512,099,651 - 12,121,122 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541512,098,009 - 12,121,722 (+)NCBIChiLan1.0ChiLan1.0
ARAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24136,902,257 - 136,930,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15135,041,803 - 135,070,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05137,014,286 - 137,042,786 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15143,126,866 - 143,153,941 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5143,127,414 - 143,153,318 (-)Ensemblpanpan1.1panPan2
ARAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,614,799 - 36,639,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,615,361 - 36,639,525 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha233,666,700 - 33,691,184 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0237,069,004 - 37,093,498 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl237,069,013 - 37,093,492 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1234,143,570 - 34,168,054 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,955,080 - 34,979,561 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0235,762,386 - 35,785,328 (-)NCBIUU_Cfam_GSD_1.0
ARAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2143,304,080 - 143,327,588 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12143,304,076 - 143,327,588 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22149,506,693 - 149,530,184 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12344,280,010 - 44,308,046 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2344,279,727 - 44,306,272 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603433,395,355 - 33,572,620 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624774881,708 - 905,690 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624774881,162 - 907,310 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000019465   ⟹   ENSSTOP00000019442
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650412,490,850 - 12,513,996 (+)Ensembl
RefSeq Acc Id: XM_005324239   ⟹   XP_005324296
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213150,915,484 - 150,940,433 (+)NCBI
SpeTri2.0NW_00493650412,490,838 - 12,514,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358158   ⟹   XP_013213612
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213150,915,483 - 150,940,433 (+)NCBI
SpeTri2.0NW_00493650412,490,838 - 12,514,256 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324296 (Get FASTA)   NCBI Sequence Viewer  
  XP_013213612 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019442.1
GenBank Protein KAG3266082 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266083 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266084 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005324296   ⟸   XM_005324239
- Peptide Label: isoform X1
- UniProtKB: I3N4Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013213612   ⟸   XM_013358158
- Peptide Label: isoform X2
- UniProtKB: I3N4Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000019442   ⟸   ENSSTOT00000019465
Protein Domains
Arf-GAP   PH   Ras-associating   Rho-GAP   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021570 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000019465.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.10.220.150 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  RA_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_ARAP UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Arap3 ENTREZGENE
PANTHER ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART ArfGap UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt I3N4Z6 ENTREZGENE, UniProtKB/TrEMBL