Myo7b (myosin VIIB) - Rat Genome Database

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Gene: Myo7b (myosin VIIB) Ictidomys tridecemlineatus
Analyze
Symbol: Myo7b
Name: myosin VIIB
RGD ID: 12446587
Description: ENCODES a protein that exhibits actin binding (inferred); ATP binding (inferred); cytoskeletal motor activity (inferred); INVOLVED IN brush border assembly (ortholog); ASSOCIATED WITH autosomal dominant thrombophilia due to protein C deficiency (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2W (ortholog); centronuclear myopathy 2 (ortholog); FOUND IN apical cytoplasm (inferred); brush border (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unconventional myosin-VIIb
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,873,403 - 97,951,859 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646943,666,057 - 43,728,167 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646943,665,836 - 43,732,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Myo7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,873,403 - 97,951,859 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646943,666,057 - 43,728,167 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646943,665,836 - 43,732,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,535,683 - 127,637,726 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,535,683 - 127,637,729 (+)EnsemblGRCh38hg38GRCh38
GRCh372128,293,259 - 128,395,301 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,009,848 - 128,111,773 (+)NCBINCBI36Build 36hg18NCBI36
Celera2121,604,332 - 121,706,245 (+)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,600,353 - 120,701,678 (+)NCBIHuRef
CHM1_12128,297,893 - 128,399,731 (+)NCBICHM1_1
T2T-CHM13v2.02127,970,920 - 128,072,980 (+)NCBIT2T-CHM13v2.0
Myo7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,092,287 - 32,169,984 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1832,092,287 - 32,170,014 (-)EnsemblGRCm39 Ensembl
GRCm381831,959,234 - 32,036,931 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1831,959,234 - 32,036,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371832,118,888 - 32,196,585 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361832,102,244 - 32,188,671 (-)NCBIMGSCv36mm8
Celera1832,449,602 - 32,527,043 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1817.89NCBI
Myo7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,862,533 - 23,944,081 (-)NCBIGRCr8
mRatBN7.21823,588,307 - 23,669,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,588,307 - 23,669,809 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,716,400 - 23,797,906 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,465,407 - 24,547,198 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,811,370 - 23,892,888 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,742,329 - 24,823,889 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,742,329 - 24,823,858 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01824,456,652 - 24,538,389 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,382,252 - 24,463,999 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1823,340,877 - 23,422,331 (-)NCBICelera
Cytogenetic Map18p12NCBI
Myo7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554592,914,628 - 2,976,436 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554592,914,409 - 2,990,591 (-)NCBIChiLan1.0ChiLan1.0
MYO7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21348,005,959 - 48,111,287 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B48,020,937 - 48,126,265 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B32,637,807 - 32,742,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B128,200,766 - 128,304,116 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,226,236 - 128,303,816 (+)Ensemblpanpan1.1panPan2
MYO7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11922,979,078 - 23,064,815 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1922,979,074 - 23,050,834 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1923,226,255 - 23,312,176 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01924,305,058 - 24,391,001 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1924,305,359 - 24,377,145 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11923,008,932 - 23,094,792 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01923,203,451 - 23,289,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01924,335,348 - 24,421,303 (-)NCBIUU_Cfam_GSD_1.0
MYO7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1559,709,943 - 59,803,046 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11559,709,938 - 59,803,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21566,420,238 - 66,434,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYO7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1102,578,211 - 2,657,617 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606120,079,138 - 20,181,020 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473214,033,495 - 14,101,713 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473214,001,973 - 14,101,924 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015359   ⟹   ENSSTOP00000013756
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493646943,666,057 - 43,728,167 (-)Ensembl
RefSeq Acc Id: XM_040294199   ⟹   XP_040150133
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530397,873,403 - 97,951,859 (+)NCBI
RefSeq Acc Id: XM_040294200   ⟹   XP_040150134
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530397,878,705 - 97,951,859 (+)NCBI
RefSeq Acc Id: XM_040294201   ⟹   XP_040150135
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530397,873,403 - 97,951,859 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040150133 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150134 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150135 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013756.3
GenBank Protein KAG3274323 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040150133   ⟸   XM_040294199
- Peptide Label: isoform X1
- UniProtKB: I3MPL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150135   ⟸   XM_040294201
- Peptide Label: isoform X2
- UniProtKB: I3MPL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150134   ⟸   XM_040294200
- Peptide Label: isoform X1
- UniProtKB: I3MPL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000013756   ⟸   ENSSTOT00000015359
Protein Domains
FERM   Myosin motor   MyTH4   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015334 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015359.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  1.20.80.10 UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  MyoVII_FERM_C1 UniProtKB/TrEMBL
  MyoVII_FERM_C2 UniProtKB/TrEMBL
  MYSc_Myo7 UniProtKB/TrEMBL
  MyTH4_dom UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Myo7b ENTREZGENE
PANTHER MYOSIN VII, XV UniProtKB/TrEMBL
  MYOSIN VIIB UniProtKB/TrEMBL
Pfam FERM_M UniProtKB/TrEMBL
  Myosin_head UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
  MYOSIN_MOTOR UniProtKB/TrEMBL
  MYTH4 UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  MYSc UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt I3MPL4 ENTREZGENE, UniProtKB/TrEMBL