Plekho1 (pleckstrin homology domain containing O1) - Rat Genome Database

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Gene: Plekho1 (pleckstrin homology domain containing O1) Ictidomys tridecemlineatus
Analyze
Symbol: Plekho1
Name: pleckstrin homology domain containing O1
RGD ID: 12445853
Description: INVOLVED IN lamellipodium morphogenesis (ortholog); myoblast fusion (ortholog); myoblast migration (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); dyschromatosis symmetrica hereditaria (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); muscle cell projection membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain containing O1, transcript variant X1; pleckstrin homology domain containing O1, transcript variant X2; pleckstrin homology domain containing O1, transcript variant X3; pleckstrin homology domain containing O1, transcript variant X4; pleckstrin homology domain-containing family O member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,409,723 - 21,416,853 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936580440,111 - 448,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Plekho1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,409,723 - 21,416,853 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936580440,111 - 448,651 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,149,646 - 150,160,065 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1150,149,183 - 150,164,720 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,121,836 - 150,132,260 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,388,794 - 148,398,449 (+)NCBINCBI36Build 36hg18NCBI36
Celera1123,237,889 - 123,247,544 (+)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,502,507 - 121,511,229 (+)NCBIHuRef
CHM1_11151,518,106 - 151,527,756 (+)NCBICHM1_1
T2T-CHM13v2.01149,274,323 - 149,284,749 (+)NCBIT2T-CHM13v2.0
Plekho1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,896,121 - 95,903,300 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,895,741 - 95,903,313 (-)EnsemblGRCm39 Ensembl
GRCm38395,988,809 - 95,999,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,988,429 - 95,996,001 (-)EnsemblGRCm38mm10GRCm38
MGSCv37395,792,751 - 95,799,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36396,074,233 - 96,081,244 (-)NCBIMGSCv36mm8
Celera397,422,723 - 97,429,850 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
Plekho1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22183,544,487 - 183,552,928 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,544,499 - 183,552,785 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,208,081 - 191,216,052 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02189,012,540 - 189,020,482 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02183,840,633 - 183,848,604 (-)NCBIRnor_WKY
Rnor_6.02198,112,104 - 198,120,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2198,112,076 - 198,120,120 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,601,880 - 217,609,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,787,503 - 190,796,057 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12190,750,270 - 190,758,811 (-)NCBI
Celera2176,073,021 - 176,080,794 (-)NCBICelera
Cytogenetic Map2q34NCBI
Plekho1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955413603,128 - 616,015 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955413603,011 - 606,487 (-)NCBIChiLan1.0ChiLan1.0
PLEKHO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11129,147,114 - 129,157,401 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,146,459 - 129,157,401 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01125,494,740 - 125,504,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PLEKHO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,402,758 - 59,411,906 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,402,834 - 59,411,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,849,824 - 58,858,981 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,398,910 - 60,408,051 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,398,979 - 60,408,250 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,248,504 - 59,257,633 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,332,396 - 59,341,732 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,059,457 - 60,068,599 (+)NCBIUU_Cfam_GSD_1.0
PLEKHO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,923,996 - 98,934,189 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,924,115 - 98,934,610 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24108,197,951 - 108,208,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,137,552 - 13,148,013 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekho1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477217,889,560 - 17,901,213 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477217,889,528 - 17,898,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013361215   ⟹   XP_013216669
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505821,413,343 - 21,416,853 (+)NCBI
SpeTri2.0NW_004936580440,121 - 447,232 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021730409   ⟹   XP_021586084
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505821,409,735 - 21,416,853 (+)NCBI
SpeTri2.0NW_004936580440,187 - 447,232 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021730411   ⟹   XP_021586086
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505821,413,341 - 21,416,853 (+)NCBI
SpeTri2.0NW_004936580440,111 - 447,232 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040287507   ⟹   XP_040143441
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505821,409,723 - 21,416,852 (+)NCBI
RefSeq Acc Id: XM_040287508   ⟹   XP_040143442
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505821,409,735 - 21,416,048 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_013216669   ⟸   XM_013361215
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021586086   ⟸   XM_021730411
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021586084   ⟸   XM_021730409
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040143441   ⟸   XM_040287507
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040143442   ⟸   XM_040287508
- Peptide Label: isoform X3
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014249 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000012763 ENTREZGENE
  ENSSTOP00000012763.3 UniProtKB/TrEMBL
  ENSSTOP00000024492.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014248.3 UniProtKB/TrEMBL
  ENSSTOT00000042629.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro CKIP-1 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PKHO1/2 UniProtKB/TrEMBL
NCBI Gene Plekho1 ENTREZGENE
PANTHER PTHR15871 UniProtKB/TrEMBL
  PTHR15871:SF1 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
UniProt A0A287CT87_ICTTR UniProtKB/TrEMBL
  I3MMJ7_ICTTR UniProtKB/TrEMBL