Tsen2 (tRNA splicing endonuclease subunit 2)

Gene: Tsen2 (tRNA splicing endonuclease subunit 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Tsen2

Name:

tRNA splicing endonuclease subunit 2

RGD ID:

12445358

Description:

ENCODES a protein that exhibits lyase activity (inferred); nucleic acid binding (inferred); tRNA-intron endonuclease activity (inferred); INVOLVED IN tRNA processing (inferred); tRNA splicing, via endonucleolytic cleavage and ligation (inferred); tRNA-type intron splice site recognition and cleavage (inferred); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH Deglutition Disorders (ortholog); genetic disease (ortholog); hemolytic-uremic syndrome (ortholog); FOUND IN centrosome (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tRNA splicing endonuclease subunit 2, transcript variant X1; tRNA splicing endonuclease subunit 2, transcript variant X2; tRNA splicing endonuclease subunit 2, transcript variant X3; tRNA-splicing endonuclease subunit Sen2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	17,714,525 - 17,745,833 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936602	1,164,227 - 1,195,221 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936602	1,163,927 - 1,195,163 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Deglutition Disorders (ISO)

genetic disease (ISO)

hemolytic-uremic syndrome (ISO)

intellectual disability (ISO)

microcephaly (ISO)

movement disease (ISO)

pontocerebellar hypoplasia (ISO)

pontocerebellar hypoplasia type 1B (ISO)

pontocerebellar hypoplasia type 2B (ISO)

RASopathy (ISO)

Vision Disorders (ISO)

Weight Gain (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

tRNA processing (IEA)

tRNA splicing, via endonucleolytic cleavage and ligation (IEA)

tRNA-type intron splice site recognition and cleavage (IEA)

Cellular Component

centrosome (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

tRNA-intron endonuclease complex (IEA)

Molecular Function

lyase activity (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

tRNA-intron endonuclease activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

tRNA maturation pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tsen2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	17,714,525 - 17,745,833 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936602	1,164,227 - 1,195,221 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936602	1,163,927 - 1,195,163 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TSEN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	12,480,231 - 12,539,624 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	12,484,421 - 12,541,549 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	12,525,979 - 12,581,123 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	12,501,028 - 12,549,812 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	12,463,261 - 12,512,159 (+)	NCBI		Celera
Cytogenetic Map	3	p25.2	NCBI
HuRef	3	12,458,994 - 12,507,895 (+)	NCBI		HuRef
CHM1_1	3	12,476,015 - 12,524,909 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	12,478,037 - 12,537,426 (+)	NCBI		T2T-CHM13v2.0

Tsen2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	115,521,652 - 115,555,297 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	115,521,625 - 115,555,589 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	115,544,659 - 115,578,350 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	115,544,664 - 115,578,628 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	115,494,722 - 115,528,354 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	115,510,323 - 115,543,955 (+)	NCBI		MGSCv36	mm8
Celera	6	117,384,279 - 117,417,834 (+)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	53.58	NCBI

Tsen2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	150,275,389 - 150,310,846 (+)	NCBI		GRCr8
mRatBN7.2	4	148,602,805 - 148,638,219 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	148,602,863 - 148,638,215 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	154,827,001 - 154,862,293 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	150,610,088 - 150,645,379 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	149,233,907 - 149,269,200 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	147,455,506 - 147,490,869 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	147,455,533 - 147,490,733 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	210,742,791 - 210,778,839 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	151,672,953 - 151,708,835 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	151,917,793 - 151,953,680 (+)	NCBI
Celera	4	137,494,385 - 137,528,921 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

Tsen2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	14,969,289 - 14,997,220 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	14,970,105 - 14,997,459 (+)	NCBI	ChiLan1.0	ChiLan1.0

TSEN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	12,471,154 - 12,524,257 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	12,475,973 - 12,529,018 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	12,410,885 - 12,463,932 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	12,754,106 - 12,800,801 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	12,759,375 - 12,800,201 (+)	Ensembl	panpan1.1		panPan2

TSEN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	6,031,295 - 6,090,938 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	6,050,357 - 6,207,981 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	6,067,927 - 6,127,172 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	6,060,280 - 6,119,929 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	6,078,684 - 6,119,841 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	5,775,670 - 5,835,307 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	6,129,564 - 6,189,194 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	6,106,273 - 6,164,648 (-)	NCBI		UU_Cfam_GSD_1.0

TSEN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	68,467,860 - 68,520,717 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	68,480,708 - 68,520,726 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	75,697,087 - 75,737,589 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TSEN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	48,458,404 - 48,510,420 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	48,463,693 - 48,510,123 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	117,993,783 - 118,042,002 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tsen2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624956	22,035 - 46,874 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624956	21,284 - 51,588 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021731987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021731988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040291005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040291013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005736096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000536 ⟹ ENSSTOP00000000483

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936602	1,164,227 - 1,195,221 (-)	Ensembl

RefSeq Acc Id:

XM_005333791 ⟹ XP_005333848

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404942	17,714,535 - 17,745,833 (+)	NCBI
SpeTri2.0	NW_004936602	1,163,927 - 1,195,163 (-)	NCBI

Sequence:

show sequence

GGCAGCGGCGTCGGCCCGCCCTCCCCGGCCGGCGTTCCCAGGTAACGGGAAGCGCGTGGCGCTG
AGGAAGAACAGTTGCCCTGAAGAATGGCGGAAGCAGTATTCCACGCCCCAAAGAGGAAAAGGAG
GGTGTATGAGAATTACGAGTCTCCACTGCCAGTCCCTCTTGGTCAGGACCAAGATCCTAAGAAA
TTCAGAATCTTCCGTGCAGAAATAATCAACAACAACGTGATTGTGAGGAGTCCCGAGGACATTA
AGCAGCTGTACGGGAAGGGCTACTTTGGGAAAGGCATTCTTTCCAGAAGCCGACCGAACTTCAC
AATTTCAGATCCTAAGCTGGTTGCTAAGTGGAAAGGTATGAAGACAGACTTGCCTGTAATCTCA
TCAAAGAAGTACCAGCGTCGTGTCGAATGGGCTGCGAGTCTCATGCACAGACAGGGGCAGGACC
CGAGAACTGTGCACGAGATCCTCAAGGAGTACACAAAACCTCTTGAACATCCTTGTGTCAGAAG
GAACGAAGGGGTTCAGGTGCATGACGCACTTGACCCTGAGATAGCTTCCACCCTGGGAAGCACA
GTGGGCACCAAGAACCTTTCTGAGATGAATGAAGACATTGGACAGTCAGACGAGCCCAGCAGGC
ACTCAAACGGCGGCCTGCAGGCGGACTCTGTGCATGACCCACTCCCCACCAAGGGCCTCGATGC
ACGGGTGGGAGAGGACACCACACCTCTGCCCCGAGATGTCCTCATCCCCCTGCGTGGCCTTCAG
CCTGAGGCTGGCAGTCAGCAAACGGGTCTTATCCATGCTGGAGAGAGAGGGCCTGACCATGAGT
ATGTGCTCGTCGTGGAAGAAGAGGTGTGTGCTGTGAGCGAGGGGGACGACGCCCCCAAAGAGGA
AGTGGTGCAAAGACAGAAATTAACATGCAGAAGAAACCCATATAGGATCTTCGAGTATTTGCAG
CTCAGCCTAGAAGAGGCTTTCTTCCTGGTCTATGCCCTGGGATGTCTCAGTATTTACTATGAGA
AGGAACCCTTGACGATACTGAAACTCTGGCAAGTTTTCACTTCCATTCAGCCCACCTTCAGGAC
CACCTACATGGCCTACCACTACTTCCGAAGCAAGGGCTGGGTGCCCAAAGTGGGGCTCAAGTAC
GGGACAGATTTCTTGCTATATTGGAAAGGCCCGCCATTCTACCATGCAAGTTATTCTGTCATCG
TTGAGCTCGTGGACGATCACTTGGAAGGCTCCCTCCGCAGGCCATTCAGTTGGAAGTCGCTGGC
CACCCTGAGCAGAATCTCAGTTAATGTCTCTAAGGAACTTATGCTGTGCTATCTGATTAAGCCC
TCCACCATGACTGACGAGGAAATGGAGTCCCCAGAATGTATGAAAAGAATTAAAGTCCAGGAGG
TGATTCTCAGTCGATGGGTTTCCTCACGAGAGAGAAGCGACCAAGATGAACTCTAGTGATTCAG
CCTCAGATTTCCCACTCACTGAGCCTTCCACAAAGTCCTTTCCCTGTAATCGTCCATCCAGCTA
TTTAGGGGAGGAAAAAGAGGCCTGTGCTGAAGCCACAAGGTCTGTCCTCGAGTCACTTGCTCGC
TGAACCCTCTAGGCCCCAGCCTGGGTCTTCATCCAGTCACTGGGGAGGTCAGACTAGATGAGTC
CAGAGAGGACTCTCCCAGGAACAGGTAGGTCTGCTCTCTGAGTTTGTACAAAAATATAATTTCC
ATTGATACAGCACTCTGCAGTTTGGGGAGCACGTTCATACACAGATATGAACAAGATCTGTCTT
ATTTGCACATCTAATCTGTTACAGAGAGAGCATCAGAGAGCAAATGTGGGGATCACGGGGCCCC
ATGTTCCATTCTTTAAATGGAGAAAGTATGAATACATCTGGGCATATCCAAGGACTTGTCCTTG
GATCTAAAAATCCATCTTGGGCTGGGGATGTGAATCAAGTGGTAGTGCGCTCGCCTGGCATGCG
TGTG

hide sequence

RefSeq Acc Id:

XM_021731988 ⟹ XP_021587663

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404942	17,714,525 - 17,745,833 (+)	NCBI
SpeTri2.0	NW_004936602	1,163,927 - 1,195,163 (-)	NCBI

Sequence:

show sequence

GGCAGCGGCGTCGGCCCGCCCTCCCCGGCCGGCGTTCCCAGGTAACGGGAAGCGCGTGGCGCTG
AGGAAGTTGCCCTGAAGAATGGCGGAAGCAGTATTCCACGCCCCAAAGAGGAAAAGGAGGGTGT
ATGAGAATTACGAGTCTCCACTGCCAGTCCCTCTTGGTCAGGACCAAGATCCTAAGAAATTCAG
AATCTTCCGTGCAGAAATAATCAACAACAACGTGATTGTGAGGAGTCCCGAGGACATTAAGCAG
CTGTACGGGAAGGGCTACTTTGGGAAAGGCATTCTTTCCAGAAGCCGACCGAACTTCACAATTT
CAGATCCTAAGCTGGTTGCTAAGTGGAAAGGTATGAAGACAGACTTGCCTGTAATCTCATCAAA
GAAGTACCAGCGTCGTGTCGAATGGGCTGCGAGTCTCATGCACAGACAGGGGCAGGACCCGAGA
ACTGTGCACGAGATCCTCAAGGAGTACACAAAACCTCTTGAACATCCTTGTGTCAGAAGGAACG
AAGGGGTTCAGGTGCATGACGCACTTGACCCTGAGATAGCTTCCACCCTGGGAAGCACAGTGGG
CACCAAGAACCTTTCTGAGATGAATGAAGACATTGGACAGTCAGACGAGCCCAGCAGGCACTCA
AACGGCGGCCTGCAGGCGGACTCTGTGCATGACCCACTCCCCACCAAGGGCCTCGATGCACGGG
TGGGAGAGGACACCACACCTCTGCCCCGAGATGTCCTCATCCCCCTGCGTGGCCTTCAGCCTGA
GGCTGGCAGTCAGCAAACGGGTCTTATCCATGCTGGAGAGAGAGGGCCTGACCATGAGTATGTG
CTCGTCGTGGAAGAAGAGGTGTGTGCTGTGAGCGAGGGGGACGACGCCCCCAAAGAGGAAGTGG
TGCAAAGACAGAAATTAACATGCAGAAGAAACCCATATAGGATCTTCGAGTATTTGCAGCTCAG
CCTAGAAGAGGCTTTCTTCCTGGTCTATGCCCTGGGATGTCTCAGTATTTACTATGAGAAGGAA
CCCTTGACGATACTGAAACTCTGGCAAGTTTTCACTTCCATTCAGCCCACCTTCAGGACCACCT
ACATGGCCTACCACTACTTCCGAAGCAAGGGCTGGGTGCCCAAAGTGGGGCTCAAGTACGGGAC
AGATTTCTTGCTATATTGGAAAGGCCCGCCATTCTACCATGCAAGTTATTCTGTCATCGTTGAG
CTCGTGGACGATCACTTGGAAGGCTCCCTCCGCAGGCCATTCAGTTGGAAGTCGCTGGCCACCC
TGAGCAGAATCTCAGTTAATGTCTCTAAGGAACTTATGCTGTGCTATCTGATTAAGCCCTCCAC
CATGACTGACGAGGAAATGGAGTCCCCAGAATGTATGAAAAGAATTAAAGTCCAGGAGGTGATT
CTCAGTCGATGGGTTTCCTCACGAGAGAGAAGCGACCAAGATGAACTCTAGTGATTCAGCCTCA
GATTTCCCACTCACTGAGCCTTCCACAAAGTCCTTTCCCTGTAATCGTCCATCCAGCTATTTAG
GGGAGGAAAAAGAGGCCTGTGCTGAAGCCACAAGGTCTGTCCTCGAGTCACTTGCTCGCTGAAC
CCTCTAGGCCCCAGCCTGGGTCTTCATCCAGTCACTGGGGAGGTCAGACTAGATGAGTCCAGAG
AGGACTCTCCCAGGAACAGGTAGGTCTGCTCTCTGAGTTTGTACAAAAATATAATTTCCATTGA
TACAGCACTCTGCAGTTTGGGGAGCACGTTCATACACAGATATGAACAAGATCTGTCTTATTTG
CACATCTAATCTGTTACAGAGAGAGCATCAGAGAGCAAATGTGGGGATCACGGGGCCCCATGTT
CCATTCTTTAAATGGAGAAAGTATGAATACATCTGGGCATATCCAAGGACTTGTCCTTGGATCT
AAAAATCCATCTTGGGCTGGGGATGTGAATCAAGTGGTAGTGCGCTCGCCTGGCATGCGTGTG

hide sequence

RefSeq Acc Id:

XM_040291005 ⟹ XP_040146939

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404942	17,717,807 - 17,745,833 (+)	NCBI

RefSeq Acc Id:

XM_040291013 ⟹ XP_040146947

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404942	17,717,806 - 17,745,833 (+)	NCBI

RefSeq Acc Id:

XR_005736096

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404942	17,714,535 - 17,745,253 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005333848	(Get FASTA)	NCBI Sequence Viewer
	XP_021587663	(Get FASTA)	NCBI Sequence Viewer
	XP_040146939	(Get FASTA)	NCBI Sequence Viewer
	XP_040146947	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000483.3
GenBank Protein	KAG3295132	(Get FASTA)	NCBI Sequence Viewer
	KAG3295133	(Get FASTA)	NCBI Sequence Viewer
	KAG3295134	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333848 ⟸ XM_005333791

- UniProtKB:

I3LWU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEAVFHAPKRKRRVYENYESPLPVPLGQDQDPKKFRIFRAEIINNNVIVRSPEDIKQLYGKGY
FGKGILSRSRPNFTISDPKLVAKWKGMKTDLPVISSKKYQRRVEWAASLMHRQGQDPRTVHEIL
KEYTKPLEHPCVRRNEGVQVHDALDPEIASTLGSTVGTKNLSEMNEDIGQSDEPSRHSNGGLQA
DSVHDPLPTKGLDARVGEDTTPLPRDVLIPLRGLQPEAGSQQTGLIHAGERGPDHEYVLVVEEE
VCAVSEGDDAPKEEVVQRQKLTCRRNPYRIFEYLQLSLEEAFFLVYALGCLSIYYEKEPLTILK
LWQVFTSIQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDFLLYWKGPPFYHASYSVIVELVDDHL
EGSLRRPFSWKSLATLSRISVNVSKELMLCYLIKPSTMTDEEMESPECMKRIKVQEVILSRWVS
SRERSDQDEL

hide sequence

RefSeq Acc Id:

XP_021587663 ⟸ XM_021731988

- UniProtKB:

I3LWU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEAVFHAPKRKRRVYENYESPLPVPLGQDQDPKKFRIFRAEIINNNVIVRSPEDIKQLYGKGY
FGKGILSRSRPNFTISDPKLVAKWKGMKTDLPVISSKKYQRRVEWAASLMHRQGQDPRTVHEIL
KEYTKPLEHPCVRRNEGVQVHDALDPEIASTLGSTVGTKNLSEMNEDIGQSDEPSRHSNGGLQA
DSVHDPLPTKGLDARVGEDTTPLPRDVLIPLRGLQPEAGSQQTGLIHAGERGPDHEYVLVVEEE
VCAVSEGDDAPKEEVVQRQKLTCRRNPYRIFEYLQLSLEEAFFLVYALGCLSIYYEKEPLTILK
LWQVFTSIQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDFLLYWKGPPFYHASYSVIVELVDDHL
EGSLRRPFSWKSLATLSRISVNVSKELMLCYLIKPSTMTDEEMESPECMKRIKVQEVILSRWVS
SRERSDQDEL

hide sequence

RefSeq Acc Id:	XP_040146947 ⟸ XM_040291013
- UniProtKB:	I3LWU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040146939 ⟸ XM_040291005
- UniProtKB:	I3LWU7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000000483 ⟸ ENSSTOT00000000536

Protein Domains

tRNA intron endonuclease catalytic tRNA intron endonuclease N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000538	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000536.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1350.10	UniProtKB/TrEMBL
InterPro	tRNA_endonuc-like_dom_sf	UniProtKB/TrEMBL
	tRNA_intron_Endo_cat-like_sf	UniProtKB/TrEMBL
	tRNA_intron_Endonuc_cat-like	UniProtKB/TrEMBL
	tRNA_intron_Endonuc_N	UniProtKB/TrEMBL
	tRNA_splic	UniProtKB/TrEMBL
	tRNA_splic_SEN2	UniProtKB/TrEMBL
NCBI Gene	Tsen2	ENTREZGENE
PANTHER	PTHR21227	UniProtKB/TrEMBL
	TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2	UniProtKB/TrEMBL
Pfam	tRNA_int_endo	UniProtKB/TrEMBL
	tRNA_int_endo_N	UniProtKB/TrEMBL
PIRSF	tRNA_splic_SEN2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53032	UniProtKB/TrEMBL
UniProt	I3LWU7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations