Mapk10 (mitogen-activated protein kinase 10) - Rat Genome Database

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Gene: Mapk10 (mitogen-activated protein kinase 10) Ictidomys tridecemlineatus
Analyze
Symbol: Mapk10
Name: mitogen-activated protein kinase 10
RGD ID: 12444270
Description: ENCODES a protein that exhibits ATP binding (ortholog); JUN kinase activity (ortholog); INVOLVED IN cellular hyperosmotic response (ortholog); JNK cascade (ortholog); JUN phosphorylation (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Generalized Epilepsy (ortholog); Lennox-Gastaut syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); mitochondrion (ortholog); neuron projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitogen-activated protein kinase 10, transcript variant X1; mitogen-activated protein kinase 10, transcript variant X2; mitogen-activated protein kinase 10, transcript variant X3; mitogen-activated protein kinase 10, transcript variant X4; mitogen-activated protein kinase 10, transcript variant X5; mitogen-activated protein kinase 10, transcript variant X6; mitogen-activated protein kinase 10, transcript variant X7; mitogen-activated protein kinase 10, transcript variant X8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052852,447,490 - 2,761,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936896230,494 - 540,071 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936896228,908 - 539,836 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
Mapk10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052852,447,490 - 2,761,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936896230,494 - 540,071 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936896228,908 - 539,836 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38486,010,405 - 86,594,074 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl485,990,007 - 86,594,625 (-)EnsemblGRCh38hg38GRCh38
GRCh37486,931,558 - 87,374,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36487,156,656 - 87,593,307 (-)NCBINCBI36Build 36hg18NCBI36
Build 34487,294,810 - 87,632,922NCBI
Celera484,225,414 - 84,570,629 (-)NCBICelera
Cytogenetic Map4q21.3NCBI
HuRef482,680,152 - 83,118,708 (-)NCBIHuRef
CHM1_1486,912,970 - 87,350,773 (-)NCBICHM1_1
T2T-CHM13v2.0489,339,877 - 89,782,667 (-)NCBIT2T-CHM13v2.0
Mapk10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395103,056,413 - 103,360,470 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5103,055,814 - 103,359,200 (-)EnsemblGRCm39 Ensembl
GRCm385102,908,547 - 103,212,604 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5102,907,948 - 103,211,334 (-)EnsemblGRCm38mm10GRCm38
MGSCv375103,336,967 - 103,640,353 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365103,152,671 - 103,451,379 (-)NCBIMGSCv36mm8
Celera5100,221,882 - 100,523,871 (-)NCBICelera
Cytogenetic Map5E5NCBI
Mapk10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2146,497,662 - 6,790,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,497,707 - 6,786,201 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx146,475,683 - 6,751,915 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0147,775,937 - 8,052,130 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0146,467,375 - 6,743,050 (+)NCBIRnor_WKY
Rnor_6.0148,079,955 - 8,371,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,080,275 - 8,368,254 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,053,697 - 8,344,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,719,595 - 8,010,694 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1147,719,594 - 8,010,694 (+)NCBI
Celera146,636,411 - 6,919,118 (+)NCBICelera
Cytogenetic Map14p22NCBI
Mapk10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554743,624,679 - 3,772,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554743,451,656 - 3,772,405 (+)NCBIChiLan1.0ChiLan1.0
MAPK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1489,056,754 - 89,392,980 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl489,059,579 - 89,392,196 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0478,326,129 - 78,756,794 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
MAPK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1329,584,437 - 9,889,118 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl329,575,492 - 9,884,325 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3232,059,481 - 32,299,296 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0329,607,730 - 9,912,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl329,597,455 - 9,907,345 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1329,698,411 - 10,025,887 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0329,545,360 - 9,851,058 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03230,098,318 - 30,403,778 (+)NCBIUU_Cfam_GSD_1.0
MAPK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8132,298,299 - 132,776,820 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18132,445,818 - 132,751,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28141,972,691 - 142,138,440 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAPK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1734,394,600 - 34,725,658 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl734,399,544 - 34,564,212 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603713,051,033 - 13,392,105 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapk10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248722,461,362 - 2,825,161 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248722,460,308 - 2,830,569 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000001817   ⟹   ENSSTOP00000001622
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936896230,548 - 444,043 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000021714   ⟹   ENSSTOP00000022831
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936896230,494 - 392,064 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000032970   ⟹   ENSSTOP00000028635
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936896230,548 - 534,223 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000036826   ⟹   ENSSTOP00000032671
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936896230,548 - 540,071 (-)Ensembl
RefSeq Acc Id: XM_005341740   ⟹   XP_005341797
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,595,137 - 2,761,815 (+)NCBI
SpeTri2.0NW_004936896228,908 - 539,836 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721082   ⟹   XP_021576757
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,568,579 - 2,761,815 (+)NCBI
SpeTri2.0NW_004936896228,908 - 418,673 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721084   ⟹   XP_021576759
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,453,021 - 2,761,815 (+)NCBI
SpeTri2.0NW_004936896228,908 - 392,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721085   ⟹   XP_021576760
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,595,137 - 2,761,815 (+)NCBI
SpeTri2.0NW_004936896230,614 - 539,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040292189   ⟹   XP_040148123
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,595,137 - 2,761,815 (+)NCBI
RefSeq Acc Id: XM_040292190   ⟹   XP_040148124
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,447,490 - 2,761,815 (+)NCBI
RefSeq Acc Id: XM_040292192   ⟹   XP_040148126
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,452,982 - 2,761,815 (+)NCBI
RefSeq Acc Id: XM_040292193   ⟹   XP_040148127
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244052852,447,492 - 2,761,815 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005341797   ⟸   XM_005341740
- Peptide Label: isoform X1
- UniProtKB: I3NEN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576757   ⟸   XM_021721082
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021576759   ⟸   XM_021721084
- Peptide Label: isoform X6
- UniProtKB: A0A287D549 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576760   ⟸   XM_021721085
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_040148124   ⟸   XM_040292190
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040148127   ⟸   XM_040292193
- Peptide Label: isoform X6
- UniProtKB: A0A287D549 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040148126   ⟸   XM_040292192
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040148123   ⟸   XM_040292189
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000022831   ⟸   ENSSTOT00000021714
RefSeq Acc Id: ENSSTOP00000001622   ⟸   ENSSTOT00000001817
RefSeq Acc Id: ENSSTOP00000032671   ⟸   ENSSTOT00000036826
RefSeq Acc Id: ENSSTOP00000028635   ⟸   ENSSTOT00000032970
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001819 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000001622 ENTREZGENE
  ENSSTOP00000001622.3 UniProtKB/TrEMBL
  ENSSTOP00000022831 ENTREZGENE
  ENSSTOP00000022831.2 UniProtKB/TrEMBL
  ENSSTOP00000028635 ENTREZGENE
  ENSSTOP00000028635.1 UniProtKB/TrEMBL
  ENSSTOP00000032671.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001817.3 UniProtKB/TrEMBL
  ENSSTOT00000021714.2 UniProtKB/TrEMBL
  ENSSTOT00000032970.1 UniProtKB/TrEMBL
  ENSSTOT00000036826.1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  MAP_kinase_CS UniProtKB/TrEMBL
  MAPK_JNK UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Mapk10 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
PRINTS JNKMAPKINASE UniProtKB/TrEMBL
PROSITE MAPK UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A287D549 ENTREZGENE, UniProtKB/TrEMBL
  I3LZ97_ICTTR UniProtKB/TrEMBL
  I3NEN4 ENTREZGENE, UniProtKB/TrEMBL