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Gene: RAPGEF2 (Rap guanine nucleotide exchange factor 2) Canis lupus familiaris
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Symbol: RAPGEF2
Name: Rap guanine nucleotide exchange factor 2
Description: ENCODES a protein that exhibits beta-1 adrenergic receptor binding (ortholog); cAMP binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway (ortholog); blood vessel development (ortholog); brain-derived neurotrophic factor receptor signaling pathway (ortholog); PARTICIPATES IN adenosine signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH familial adult myoclonic epilepsy 7 (ortholog); Myoclonic Epilepsies (ortholog); FOUND IN cell-cell junction; cytoplasm (ortholog); late endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: CNrasGEF; Cyclic nucleotide ras GEF; Neural RAP guanine nucleotide exchange protein; nRap GEP; NRAPGEP; PDZ domain-containing guanine nucleotide exchange factor 1; PDZ-GEF1; PDZGEF1; RA-GEF-1; Rap guanine nucleotide exchange factor (GEF) 2; Ras/Rap1-associating GEF-1
Orthologs:
Homo sapiens (human) : RAPGEF2 (Rap guanine nucleotide exchange factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Rapgef2 (Rap guanine nucleotide exchange factor (GEF) 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rapgef2 (Rap guanine nucleotide exchange factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rapgef2 (Rap guanine nucleotide exchange factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RAPGEF2 (Rap guanine nucleotide exchange factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rapgef2 (Rap guanine nucleotide exchange factor 2)
Sus scrofa (pig) : RAPGEF2 (Rap guanine nucleotide exchange factor 2)
Chlorocebus sabaeus (African green monkey) : RAPGEF2 (Rap guanine nucleotide exchange factor 2)
Heterocephalus glaber (naked mole-rat) : Rapgef2 (Rap guanine nucleotide exchange factor 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1556,174,578 - 56,352,569 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11556,133,094 - 56,353,609 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on RAPGEF2
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 12434741
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.