LRRC15 (leucine rich repeat containing 15) - Rat Genome Database

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Gene: LRRC15 (leucine rich repeat containing 15) Canis lupus familiaris
Analyze
Symbol: LRRC15
Name: leucine rich repeat containing 15
RGD ID: 12433009
Description: ENCODES a protein that exhibits collagen binding (inferred); fibronectin binding (inferred); laminin binding (inferred); INVOLVED IN negative regulation of protein localization to plasma membrane (inferred); negative regulation of viral entry into host cell (inferred); positive regulation of cell migration (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat-containing protein 15
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13331,332,502 - 31,345,895 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3331,332,496 - 31,342,583 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3331,364,113 - 31,377,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03331,592,490 - 31,605,874 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13331,389,449 - 31,402,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03331,418,407 - 31,431,789 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03332,105,985 - 32,118,522 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LRRC15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13331,332,502 - 31,345,895 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3331,332,496 - 31,342,583 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3331,364,113 - 31,377,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03331,592,490 - 31,605,874 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13331,389,449 - 31,402,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03331,418,407 - 31,431,789 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03332,105,985 - 32,118,522 (-)NCBIUU_Cfam_GSD_1.0
LRRC15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383194,355,249 - 194,369,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3194,355,249 - 194,369,743 (-)EnsemblGRCh38hg38GRCh38
GRCh373194,075,978 - 194,090,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363195,557,273 - 195,571,761 (-)NCBINCBI36Build 36hg18NCBI36
Build 343195,557,280 - 195,571,769NCBI
Celera3192,490,979 - 192,505,408 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3191,455,388 - 191,469,818 (-)NCBIHuRef
CHM1_13194,038,840 - 194,053,338 (-)NCBICHM1_1
T2T-CHM13v2.03197,053,410 - 197,067,898 (-)NCBIT2T-CHM13v2.0
Lrrc15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391630,088,120 - 30,102,072 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1630,088,120 - 30,102,074 (-)EnsemblGRCm39 Ensembl
GRCm381630,269,302 - 30,283,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1630,269,302 - 30,283,256 (-)EnsemblGRCm38mm10GRCm38
MGSCv371630,269,388 - 30,283,340 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361630,189,051 - 30,202,972 (-)NCBIMGSCv36mm8
Celera1630,776,217 - 30,790,244 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1621.23NCBI
Lrrc15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,974,708 - 83,989,157 (+)NCBIGRCr8
mRatBN7.21170,469,817 - 70,484,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1170,469,804 - 70,484,267 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1179,322,922 - 79,324,658 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,957,413 - 71,959,149 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01171,012,023 - 71,013,759 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01174,040,846 - 74,052,179 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1174,050,166 - 74,051,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01177,102,016 - 77,113,020 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,377,090 - 72,378,826 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11172,434,678 - 72,436,415 (+)NCBI
Celera1169,452,040 - 69,453,776 (+)NCBICelera
Cytogenetic Map11q22NCBI
Lrrc15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542014,407,926 - 14,409,656 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542014,401,080 - 14,410,277 (+)NCBIChiLan1.0ChiLan1.0
LRRC15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22192,278,010 - 192,292,470 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13192,286,051 - 192,290,830 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03191,655,181 - 191,666,727 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13201,968,851 - 201,980,636 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3201,970,221 - 201,974,286 (-)Ensemblpanpan1.1panPan2
Lrrc15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602123,802,384 - 123,808,008 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936711441,804 - 443,615 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936711441,804 - 443,615 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13131,343,940 - 131,345,685 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113131,339,778 - 131,354,691 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213140,841,378 - 140,849,189 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11588,451,090 - 88,465,241 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1588,455,015 - 88,456,760 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604162,137,819 - 62,152,046 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473063,400,463 - 63,409,006 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LRRC15
160 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system
High
Medium 6
Low 3 3
Below cutoff 5 2 12 1 5 1 1 9 5 7

Sequence


RefSeq Acc Id: ENSCAFT00000021351   ⟹   ENSCAFP00000034956
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3331,332,496 - 31,342,583 (+)Ensembl
RefSeq Acc Id: XM_005639635   ⟹   XP_005639692
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13331,332,502 - 31,345,895 (+)NCBI
Dog10K_Boxer_Tasha3331,364,113 - 31,377,495 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038445357   ⟹   XP_038301285
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03331,592,490 - 31,605,874 (+)NCBI
RefSeq Acc Id: XM_038519592   ⟹   XP_038375520
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13331,389,449 - 31,402,834 (+)NCBI
RefSeq Acc Id: XM_038582489   ⟹   XP_038438417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03332,105,985 - 32,118,522 (-)NCBI
RefSeq Acc Id: XM_038647646   ⟹   XP_038503574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03331,418,407 - 31,431,789 (+)NCBI
RefSeq Acc Id: XP_005639692   ⟸   XM_005639635
- UniProtKB: A0A8C0RST9 (UniProtKB/TrEMBL),   A0A8P0NNC5 (UniProtKB/TrEMBL),   A0A8I3QB59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000034956   ⟸   ENSCAFT00000021351
RefSeq Acc Id: XP_038375520   ⟸   XM_038519592
RefSeq Acc Id: XP_038503574   ⟸   XM_038647646
RefSeq Acc Id: XP_038301285   ⟸   XM_038445357
- UniProtKB: A0A8C0RST9 (UniProtKB/TrEMBL),   A0A8P0NNC5 (UniProtKB/TrEMBL),   A0A8I3QB59 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038438417   ⟸   XM_038582489
- UniProtKB: A0A8I3QB59 (UniProtKB/TrEMBL)
Protein Domains
LRRCT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013466 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030024490 UniProtKB/TrEMBL
  ENSCAFG00040019912 UniProtKB/TrEMBL
  ENSCAFG00845030907 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000021351.5 UniProtKB/TrEMBL
  ENSCAFT00030045051.1 UniProtKB/TrEMBL
  ENSCAFT00040036803.1 UniProtKB/TrEMBL
  ENSCAFT00845054930.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:488041 UniProtKB/TrEMBL
NCBI Gene LRRC15 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15 UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A8C0RST9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QB59 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NNC5 ENTREZGENE
UniProt Secondary A0A8P0NNC5 UniProtKB/TrEMBL
VGNC ID VGNC:42786 ENTREZGENE