SMAD3 (SMAD family member 3) - Rat Genome Database

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Gene: SMAD3 (SMAD family member 3) Canis lupus familiaris
Analyze
Symbol: SMAD3
Name: SMAD family member 3
RGD ID: 12428771
Description: ENCODES a protein that exhibits beta-catenin binding (ortholog); DNA-binding transcription factor activity (ortholog); enzyme binding (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (ortholog); adrenal gland development (ortholog); apoptotic process (ortholog); PARTICIPATES IN activin signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); Aneurysm (ortholog); aortic aneurysm (ortholog); FOUND IN nucleus (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Madh3; mothers against decapentaplegic homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13031,246,313 - 31,360,098 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3031,245,657 - 31,363,337 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3031,175,971 - 31,289,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03031,444,224 - 31,557,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3031,444,224 - 31,561,176 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13031,371,657 - 31,485,227 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03031,431,846 - 31,545,247 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03031,673,713 - 31,787,293 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  (ISO)
activin receptor signaling pathway  (IEA)
adrenal gland development  (ISO)
anatomical structure morphogenesis  (IEA)
apoptotic process  (IEA,ISO)
cell differentiation  (IEA)
cell population proliferation  (IEA,ISO)
cell-cell junction organization  (IEA)
cellular response to glucose stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (IEA,ISO)
cellular response to virus  (IEA)
developmental growth  (IEA,ISO)
embryonic cranial skeleton morphogenesis  (IEA,ISO)
embryonic foregut morphogenesis  (IEA,ISO)
embryonic pattern specification  (IEA,ISO)
endoderm development  (IEA,ISO)
extrinsic apoptotic signaling pathway  (IEA)
gastrulation  (IEA,ISO)
heart looping  (IEA,ISO)
immune response  (IEA)
immune system development  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
JNK cascade  (IEA)
lens fiber cell differentiation  (IEA,ISO)
liver development  (IEA,ISO)
MAPK cascade  (IEA)
mesoderm formation  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cardiac muscle hypertrophy in response to stress  (ISO)
negative regulation of cell growth  (IEA)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of cytosolic calcium ion concentration  (IEA)
negative regulation of fat cell differentiation  (IEA)
negative regulation of gene expression  (IEA,ISO)
negative regulation of inflammatory response  (IEA)
negative regulation of lung blood pressure  (ISO)
negative regulation of miRNA transcription  (IEA)
negative regulation of osteoblast differentiation  (IEA,ISO)
negative regulation of osteoblast proliferation  (IEA)
negative regulation of protein catabolic process  (ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
negative regulation of wound healing  (IEA)
nodal signaling pathway  (IEA)
osteoblast development  (IEA,ISO)
osteoblast differentiation  (IEA)
paraxial mesoderm morphogenesis  (IEA,ISO)
pericardium development  (IEA,ISO)
positive regulation of alkaline phosphatase activity  (ISO)
positive regulation of bone mineralization  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of chondrocyte differentiation  (IEA)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of extracellular matrix assembly  (IEA,ISO)
positive regulation of focal adhesion assembly  (ISO)
positive regulation of gene expression  (IEA)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of miRNA transcription  (IEA,ISO)
positive regulation of nitric oxide biosynthetic process  (IEA)
positive regulation of positive chemotaxis  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of transforming growth factor beta3 production  (ISO)
protein stabilization  (ISO)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell proliferation  (IEA,ISO)
regulation of immune response  (IEA)
regulation of striated muscle tissue development  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA)
regulation of transforming growth factor beta receptor signaling pathway  (IEA,ISO)
regulation of transforming growth factor beta2 production  (IEA)
response to angiotensin  (IEA,ISO)
response to hypoxia  (IEA)
response to transforming growth factor beta  (IEA,ISO)
signal transduction involved in regulation of gene expression  (ISO)
skeletal system development  (IEA,ISO)
SMAD protein signal transduction  (IEA,ISO)
somitogenesis  (IEA,ISO)
T cell activation  (IEA)
thyroid gland development  (IEA,ISO)
transdifferentiation  (ISO)
transforming growth factor beta receptor signaling pathway  (IEA,ISO)
ureteric bud development  (IEA)

Cellular Component

Molecular Function
beta-catenin binding  (ISO)
bHLH transcription factor binding  (IEA)
chromatin binding  (IEA)
chromatin DNA binding  (IEA)
cis-regulatory region sequence-specific DNA binding  (IEA)
co-SMAD binding  (IEA)
collagen binding  (IEA)
DEAD/H-box RNA helicase binding  (IEA)
DNA binding  (IEA)
DNA-binding transcription activator activity, RNA polymerase II-specific  (IEA)
DNA-binding transcription factor activity  (IEA,ISO)
DNA-binding transcription factor activity, RNA polymerase II-specific  (IEA)
DNA-binding transcription factor binding  (IEA)
DNA-binding transcription repressor activity  (IEA)
double-stranded DNA binding  (IEA)
enzyme binding  (ISO)
I-SMAD binding  (IEA)
identical protein binding  (IEA)
metal ion binding  (IEA)
nuclear glucocorticoid receptor binding  (IEA)
nuclear mineralocorticoid receptor binding  (IEA)
nuclear receptor binding  (IEA)
phosphatase binding  (IEA)
promoter-specific chromatin binding  (IEA)
protein binding  (ISO)
protein homodimerization activity  (IEA)
protein kinase binding  (IEA)
R-SMAD binding  (IEA)
RNA polymerase II cis-regulatory region sequence-specific DNA binding  (IEA)
RNA polymerase II transcription regulatory region sequence-specific DNA binding  (IEA)
RNA polymerase II-specific DNA-binding transcription factor binding  (IEA)
sequence-specific DNA binding  (IEA,ISO)
sterol response element binding  (IEA)
transcription cis-regulatory region binding  (IEA)
transcription coactivator binding  (IEA)
transcription corepressor binding  (IEA)
transcription factor binding  (ISO)
transforming growth factor beta receptor binding  (IEA)
ubiquitin binding  (IEA)
ubiquitin protein ligase binding  (IEA)
zinc ion binding  (IEA)

References
Additional References at PubMed
PMID:20221813   PMID:22301074   PMID:23579028   PMID:30032202  


Genomics

Comparative Map Data
SMAD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13031,246,313 - 31,360,098 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3031,245,657 - 31,363,337 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3031,175,971 - 31,289,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03031,444,224 - 31,557,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3031,444,224 - 31,561,176 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13031,371,657 - 31,485,227 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03031,431,846 - 31,545,247 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03031,673,713 - 31,787,293 (+)NCBIUU_Cfam_GSD_1.0
SMAD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381567,065,602 - 67,195,169 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1567,063,763 - 67,195,173 (+)EnsemblGRCh38hg38GRCh38
GRCh371567,357,940 - 67,487,507 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361565,145,249 - 65,274,587 (+)NCBINCBI36Build 36hg18NCBI36
Build 341565,145,248 - 65,274,586NCBI
Celera1544,246,635 - 44,375,039 (+)NCBICelera
Cytogenetic Map15q22.33NCBI
HuRef1544,193,465 - 44,321,904 (+)NCBIHuRef
CHM1_11567,476,260 - 67,605,488 (+)NCBICHM1_1
T2T-CHM13v2.01564,885,345 - 65,017,070 (+)NCBIT2T-CHM13v2.0
Smad3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39963,554,048 - 63,665,276 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl963,554,049 - 63,665,276 (-)EnsemblGRCm39 Ensembl
GRCm38963,646,766 - 63,757,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl963,646,767 - 63,757,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv37963,494,574 - 63,605,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36963,444,773 - 63,556,000 (-)NCBIMGSCv36mm8
Celera960,869,117 - 60,980,879 (-)NCBICelera
Cytogenetic Map9CNCBI
cM Map934.22NCBI
Smad3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8873,022,204 - 73,132,324 (-)NCBIGRCr8
mRatBN7.2864,126,829 - 64,236,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl864,110,039 - 64,236,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx869,641,910 - 69,752,073 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0867,914,370 - 68,024,539 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0865,784,499 - 65,894,665 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0868,569,530 - 68,678,349 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl868,569,530 - 68,678,349 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0868,290,927 - 68,397,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4867,803,909 - 67,952,056 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1867,822,964 - 67,971,110 (-)NCBI
Celera863,537,497 - 63,647,062 (-)NCBICelera
Cytogenetic Map8q24NCBI
Smad3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554508,747,651 - 8,842,136 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554508,747,651 - 8,842,003 (-)NCBIChiLan1.0ChiLan1.0
SMAD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21656,319,096 - 56,448,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11560,491,695 - 60,621,061 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01546,013,764 - 46,143,126 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11564,284,949 - 64,414,185 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1564,284,949 - 64,414,185 (+)Ensemblpanpan1.1panPan2
Smad3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640109,232,767 - 109,341,735 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647127,080,575 - 27,189,793 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647127,080,662 - 27,185,861 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMAD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1164,998,103 - 165,124,449 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11164,998,457 - 165,124,455 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21182,902,348 - 182,926,370 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMAD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12616,319,959 - 16,446,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2616,320,933 - 16,446,527 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048125,021,354 - 125,151,320 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smad3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247815,795,652 - 5,890,371 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247815,795,652 - 5,890,047 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SMAD3
1847 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 5 2 2 6 10 2
Low 2 5 17 6 4 6 4 6 6 4 4
Below cutoff 4

Sequence


RefSeq Acc Id: ENSCAFT00000027577   ⟹   ENSCAFP00000025647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3031,245,657 - 31,360,098 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000060635   ⟹   ENSCAFP00000062564
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3031,246,313 - 31,360,098 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000085933   ⟹   ENSCAFP00000045707
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3031,245,657 - 31,363,337 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845029517   ⟹   ENSCAFP00845023188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3031,444,224 - 31,561,176 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845029611   ⟹   ENSCAFP00845023256
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3031,444,224 - 31,557,937 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845029701   ⟹   ENSCAFP00845023329
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3031,444,224 - 31,557,937 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845029744   ⟹   ENSCAFP00845023362
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3031,450,505 - 31,557,937 (+)Ensembl
RefSeq Acc Id: NM_001170829   ⟹   NP_001164300
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13031,246,313 - 31,360,098 (+)NCBI
Dog10K_Boxer_Tasha3031,175,971 - 31,289,442 (+)NCBI
ROS_Cfam_1.03031,444,224 - 31,557,937 (+)NCBI
UMICH_Zoey_3.13031,371,657 - 31,485,227 (+)NCBI
UNSW_CanFamBas_1.03031,431,846 - 31,545,247 (+)NCBI
UU_Cfam_GSD_1.03031,673,713 - 31,787,293 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038441749   ⟹   XP_038297677
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03031,521,076 - 31,557,801 (+)NCBI
RefSeq Acc Id: XM_038441750   ⟹   XP_038297678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03031,450,687 - 31,557,801 (+)NCBI
RefSeq Acc Id: XM_038441751   ⟹   XP_038297679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03031,537,248 - 31,557,801 (+)NCBI
RefSeq Acc Id: NP_001164300   ⟸   NM_001170829
- UniProtKB: A0A8C0K4R2 (UniProtKB/TrEMBL),   A0A8C0N781 (UniProtKB/TrEMBL),   D2YYC0 (UniProtKB/TrEMBL),   A0A8C0TUT2 (UniProtKB/TrEMBL),   A0A8I3P2U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000062564   ⟸   ENSCAFT00000060635
RefSeq Acc Id: ENSCAFP00000025647   ⟸   ENSCAFT00000027577
RefSeq Acc Id: ENSCAFP00000045707   ⟸   ENSCAFT00000085933
RefSeq Acc Id: XP_038297678   ⟸   XM_038441750
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038297677   ⟸   XM_038441749
- Peptide Label: isoform X1
- UniProtKB: A0A8I3NW17 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038297679   ⟸   XM_038441751
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MMU1 (UniProtKB/TrEMBL),   A0A8P0P8P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845023329   ⟸   ENSCAFT00845029701
RefSeq Acc Id: ENSCAFP00845023256   ⟸   ENSCAFT00845029611
RefSeq Acc Id: ENSCAFP00845023362   ⟸   ENSCAFT00845029744
RefSeq Acc Id: ENSCAFP00845023188   ⟸   ENSCAFT00845029517
Protein Domains
MH1   MH2

Promoters
RGD ID:13688564
Promoter ID:EPDNEW_C6634
Type:multiple initiation site
Name:SMAD3_1
Description:SMAD family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13031,246,028 - 31,246,088EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017388 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00000017567 UniProtKB/TrEMBL
  ENSCAFG00030012534 UniProtKB/TrEMBL
  ENSCAFG00040025738 UniProtKB/TrEMBL
  ENSCAFG00845002338 UniProtKB/TrEMBL
  ENSCAFG00845016639 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027577.5 UniProtKB/TrEMBL
  ENSCAFT00000060635.2 UniProtKB/TrEMBL
  ENSCAFT00000069480.2 UniProtKB/TrEMBL
  ENSCAFT00000085933.2 UniProtKB/TrEMBL
  ENSCAFT00030023266.1 UniProtKB/TrEMBL
  ENSCAFT00030023345.1 UniProtKB/TrEMBL
  ENSCAFT00040048059.1 UniProtKB/TrEMBL
  ENSCAFT00040048068.1 UniProtKB/TrEMBL
  ENSCAFT00040048069.1 UniProtKB/TrEMBL
  ENSCAFT00845004190.1 UniProtKB/TrEMBL
  ENSCAFT00845029517.1 UniProtKB/TrEMBL
  ENSCAFT00845029611 ENTREZGENE
  ENSCAFT00845029611.1 UniProtKB/TrEMBL
  ENSCAFT00845029701.1 UniProtKB/TrEMBL
  ENSCAFT00845029744.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.10 UniProtKB/TrEMBL
  3.90.520.10 UniProtKB/TrEMBL
InterPro Dwarfin UniProtKB/TrEMBL
  MAD_homology1_Dwarfin-type UniProtKB/TrEMBL
  MAD_homology_MH1 UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/TrEMBL
  SMAD_dom_Dwarfin-type UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
  SMAD_MH1_sf UniProtKB/TrEMBL
KEGG Report cfa:610902 UniProtKB/TrEMBL
NCBI Gene SMAD3 ENTREZGENE
PANTHER MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG UniProtKB/TrEMBL
  MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 3 UniProtKB/TrEMBL
  PTHR13703 UniProtKB/TrEMBL
Pfam MH1 UniProtKB/TrEMBL
  MH2 UniProtKB/TrEMBL
PROSITE MH1 UniProtKB/TrEMBL
  MH2 UniProtKB/TrEMBL
SMART DWA UniProtKB/TrEMBL
  DWB UniProtKB/TrEMBL
Superfamily-SCOP SSF49879 UniProtKB/TrEMBL
  SSF56366 UniProtKB/TrEMBL
UniProt A0A8C0K4R2 ENTREZGENE
  A0A8C0N781 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TUT2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TZ75_CANLF UniProtKB/TrEMBL
  A0A8I3MMU1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NW17 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P2U7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RZF0_CANLF UniProtKB/TrEMBL
  A0A8P0NVX1_CANLF UniProtKB/TrEMBL
  A0A8P0P8P9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SLD7_CANLF UniProtKB/TrEMBL
  D2YYC0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46520 ENTREZGENE