LOC485221 (olfactory receptor 52M1) - Rat Genome Database

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Gene: LOC485221 (olfactory receptor 52M1) Canis lupus familiaris
Analyze
Symbol: LOC485221
Name: olfactory receptor 52M1
RGD ID: 12427517
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cOR52M1P; cOR52M1P olfactory receptor family 52 subfamily M pseudogene; olfactory receptor family 52 subfamily M; olfactory receptor family 52 subfamily M member 1; OR52M1
RGD Orthologs
Human
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12126,695,559 - 26,696,397 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2126,464,259 - 26,465,310 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,904,924 - 26,905,975 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12126,694,577 - 26,695,628 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,911,168 - 26,912,219 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,813,588 - 26,814,639 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14962662   PMID:22301074  


Genomics

Comparative Map Data
LOC485221
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12126,695,559 - 26,696,397 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2126,464,259 - 26,465,310 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,904,924 - 26,905,975 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12126,694,577 - 26,695,628 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,911,168 - 26,912,219 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,813,588 - 26,814,639 (-)NCBIUU_Cfam_GSD_1.0
OR52M1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38114,545,191 - 4,546,144 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl114,545,191 - 4,546,144 (+)EnsemblGRCh38hg38GRCh38
GRCh37114,566,421 - 4,567,374 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36114,522,997 - 4,523,950 (+)NCBINCBI36Build 36hg18NCBI36
Build 34114,522,996 - 4,523,950NCBI
Celera114,690,621 - 4,691,574 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef114,224,847 - 4,225,800 (+)NCBIHuRef
CHM1_1114,566,352 - 4,567,305 (+)NCBICHM1_1
T2T-CHM13v2.0114,610,461 - 4,611,414 (+)NCBIT2T-CHM13v2.0
LOC100978707
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v297,007,096 - 7,008,049 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1116,963,872 - 6,964,825 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,720,053 - 4,721,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1114,385,239 - 4,386,192 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl114,385,239 - 4,386,192 (+)Ensemblpanpan1.1panPan2
LOC100516631
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.195,701,933 - 5,709,356 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.296,394,254 - 6,395,207 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in LOC485221
8 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low 3
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: XM_038429560   ⟹   XP_038285488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,904,924 - 26,905,975 (-)NCBI
RefSeq Acc Id: XM_038456046   ⟹   XP_038311974
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2126,464,259 - 26,465,310 (-)NCBI
RefSeq Acc Id: XM_038506145   ⟹   XP_038362073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12126,694,577 - 26,695,628 (-)NCBI
RefSeq Acc Id: XM_038568145   ⟹   XP_038424073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,813,588 - 26,814,639 (-)NCBI
RefSeq Acc Id: XM_038632241   ⟹   XP_038488169
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,911,168 - 26,912,219 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038362073   ⟸   XM_038506145
RefSeq Acc Id: XP_038488169   ⟸   XM_038632241
RefSeq Acc Id: XP_038285488   ⟸   XM_038429560
- UniProtKB: A0A8C0RNW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311974   ⟸   XM_038456046
- UniProtKB: A0A8C0RNW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424073   ⟸   XM_038568145
- UniProtKB: A0A8C0RNW2 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030019554 UniProtKB/TrEMBL
  ENSCAFG00040022466 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030035883.1 UniProtKB/TrEMBL
  ENSCAFT00040041705.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene cOR52M1P ENTREZGENE
PANTHER OLFACTORY RECEPTOR 52M1 UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 56B1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0RNW2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC485221  olfactory receptor 52M1  OR52M1  olfactory receptor family 52 subfamily M member 1  Symbol and/or name change 5135510 APPROVED
2020-11-24 OR52M1  olfactory receptor family 52 subfamily M member 1  cOR52M1P  cOR52M1P olfactory receptor family 52 subfamily M pseudogene  Symbol and/or name change 5135510 APPROVED