FOXRED1 (FAD dependent oxidoreductase domain containing 1) - Rat Genome Database

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Gene: FOXRED1 (FAD dependent oxidoreductase domain containing 1) Canis lupus familiaris
Analyze
Symbol: FOXRED1
Name: FAD dependent oxidoreductase domain containing 1
RGD ID: 12424958
Description: ENCODES a protein that exhibits oxidoreductase activity (inferred); INVOLVED IN mitochondrial respiratory chain complex I assembly (inferred); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Developmental Disabilities (ortholog); Dwarfism (ortholog); FOUND IN mitochondrial respiratory chain complex I (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FAD-dependent oxidoreductase domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,239,740 - 8,247,341 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,240,132 - 8,247,314 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,300,965 - 8,308,559 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,195,363 - 8,202,942 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,195,378 - 8,202,917 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,264,961 - 8,272,555 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,238,707 - 8,246,268 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,272,899 - 8,280,455 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FOXRED1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,239,740 - 8,247,341 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,240,132 - 8,247,314 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,300,965 - 8,308,559 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,195,363 - 8,202,942 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,195,378 - 8,202,917 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,264,961 - 8,272,555 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,238,707 - 8,246,268 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,272,899 - 8,280,455 (-)NCBIUU_Cfam_GSD_1.0
FOXRED1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811126,269,154 - 126,278,126 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11126,269,024 - 126,278,131 (+)EnsemblGRCh38hg38GRCh38
GRCh3711126,139,049 - 126,148,021 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,644,265 - 125,653,237 (+)NCBINCBI36Build 36hg18NCBI36
Celera11123,304,079 - 123,313,220 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11122,081,327 - 122,093,091 (+)NCBIHuRef
CHM1_111126,025,226 - 126,034,303 (+)NCBICHM1_1
T2T-CHM13v2.011126,298,638 - 126,309,536 (+)NCBIT2T-CHM13v2.0
Foxred1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39935,115,504 - 35,122,499 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl935,115,502 - 35,122,351 (-)EnsemblGRCm39 Ensembl
GRCm38935,204,208 - 35,211,171 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl935,204,206 - 35,211,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv37935,011,793 - 35,018,510 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36934,953,879 - 34,960,596 (-)NCBIMGSCv36mm8
Celera932,440,923 - 32,447,642 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.08NCBI
Foxred1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,789,557 - 41,818,064 (-)NCBIGRCr8
mRatBN7.2833,551,010 - 33,560,227 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,551,013 - 33,560,192 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0836,401,317 - 36,410,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,403,493 - 36,410,612 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0836,420,701 - 36,428,788 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4834,985,196 - 34,986,384 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1834,993,476 - 34,999,272 (-)NCBI
Celera834,970,544 - 34,979,821 (-)NCBICelera
Cytogenetic Map8q21NCBI
Foxred1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541227,293,467 - 27,300,522 (+)NCBIChiLan1.0ChiLan1.0
FOXRED1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,952,673 - 126,965,031 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111128,060,337 - 128,072,715 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011121,083,245 - 121,096,296 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,993,363 - 125,005,798 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,993,070 - 125,005,798 (+)Ensemblpanpan1.1panPan2
Foxred1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947108,499,870 - 108,507,053 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365725,943,186 - 5,950,502 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365725,943,309 - 5,950,476 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXRED1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl953,365,250 - 53,372,952 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1953,365,260 - 53,372,955 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2959,028,677 - 59,036,374 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXRED1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11117,394,426 - 117,404,692 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1117,394,587 - 117,404,258 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660438,666,968 - 8,677,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxred1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624812423,109 - 433,466 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624812423,000 - 429,660 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FOXRED1
119 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 10 6
Low 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000016603   ⟹   ENSCAFP00000015364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl58,240,132 - 8,247,314 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016638   ⟹   ENSCAFP00845012944
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl58,195,378 - 8,202,917 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016704   ⟹   ENSCAFP00845013000
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl58,195,395 - 8,202,917 (-)Ensembl
RefSeq Acc Id: XM_003639050   ⟹   XP_003639098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.158,239,740 - 8,247,341 (-)NCBI
Dog10K_Boxer_Tasha58,300,965 - 8,308,559 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038474558   ⟹   XP_038330486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.158,264,961 - 8,272,555 (-)NCBI
RefSeq Acc Id: XM_038535689   ⟹   XP_038391617
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.058,272,899 - 8,280,455 (-)NCBI
RefSeq Acc Id: XM_038599896   ⟹   XP_038455824
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.058,238,707 - 8,246,268 (-)NCBI
RefSeq Acc Id: XM_038664438   ⟹   XP_038520366
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.058,195,363 - 8,202,942 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003639098   ⟸   XM_003639050
- UniProtKB: A0A8C0SRV4 (UniProtKB/TrEMBL),   A0A8I3N706 (UniProtKB/TrEMBL),   A0A8I3RWV5 (UniProtKB/TrEMBL),   A0A8P0TU67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000015364   ⟸   ENSCAFT00000016603
RefSeq Acc Id: XP_038330486   ⟸   XM_038474558
RefSeq Acc Id: XP_038455824   ⟸   XM_038599896
RefSeq Acc Id: XP_038520366   ⟸   XM_038664438
- UniProtKB: A0A8C0SRV4 (UniProtKB/TrEMBL),   A0A8I3N706 (UniProtKB/TrEMBL),   A0A8I3RWV5 (UniProtKB/TrEMBL),   A0A8P0TU67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391617   ⟸   XM_038535689
- UniProtKB: A0A8C0SRV4 (UniProtKB/TrEMBL),   A0A8I3N706 (UniProtKB/TrEMBL),   A0A8I3RWV5 (UniProtKB/TrEMBL),   A0A8P0TU67 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845012944   ⟸   ENSCAFT00845016638
RefSeq Acc Id: ENSCAFP00845013000   ⟸   ENSCAFT00845016704
Protein Domains
FAD dependent oxidoreductase

Promoters
RGD ID:13683097
Promoter ID:EPDNEW_C1167
Type:multiple initiation site
Name:FOXRED1_1
Description:FAD dependent oxidoreductase domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.158,247,302 - 8,247,362EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010449 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000124 UniProtKB/TrEMBL
  ENSCAFG00040016046 UniProtKB/TrEMBL
  ENSCAFG00845009437 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016603.5 UniProtKB/TrEMBL
  ENSCAFT00000109033.1 UniProtKB/TrEMBL
  ENSCAFT00030000220.1 UniProtKB/TrEMBL
  ENSCAFT00030000232.1 UniProtKB/TrEMBL
  ENSCAFT00040029643.1 UniProtKB/TrEMBL
  ENSCAFT00845016638 ENTREZGENE
  ENSCAFT00845016638.1 UniProtKB/TrEMBL
  ENSCAFT00845016704.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
  D-Amino Acid Oxidase, subunit A, domain 2 UniProtKB/TrEMBL
InterPro FAD-dep_OxRdtase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:100856312 UniProtKB/TrEMBL
NCBI Gene FOXRED1 ENTREZGENE
PANTHER FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  SARCOSINE DEHYDROGENASE-RELATED UniProtKB/TrEMBL
Pfam DAO UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0A8C0M021_CANLF UniProtKB/TrEMBL
  A0A8C0SRV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N706 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RWV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TU67 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40971 ENTREZGENE