LOC100687968 (C-type lectin domain family 2 member F-like) - Rat Genome Database

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Gene: LOC100687968 (C-type lectin domain family 2 member F-like) Canis lupus familiaris
Analyze
Symbol: LOC100687968
Name: C-type lectin domain family 2 member F-like
RGD ID: 12424891
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein phosphatase binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN natural killer cell mediated cytotoxicity (ortholog); negative regulation of natural killer cell chemotaxis (ortholog); negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,059,707 - 36,068,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2710,555,689 - 10,564,069 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02736,406,096 - 36,414,471 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12736,293,162 - 36,301,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02736,316,965 - 36,325,348 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02710,077,763 - 10,086,143 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC100687968
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,059,707 - 36,068,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2710,555,689 - 10,564,069 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02736,406,096 - 36,414,471 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12736,293,162 - 36,301,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02736,316,965 - 36,325,348 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02710,077,763 - 10,086,143 (-)NCBIUU_Cfam_GSD_1.0
KLRC4-KLRK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,372,353 - 10,410,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,372,353 - 10,391,874 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,372,353 - 10,410,146 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,524,952 - 10,562,745 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12p13.2NCBI
HuRef1210,267,379 - 10,305,170 (-)NCBIHuRef
CHM1_11210,494,385 - 10,532,177 (-)NCBICHM1_1
T2T-CHM13v2.01210,259,174 - 10,296,963 (-)NCBIT2T-CHM13v2.0
Clec2m
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396129,299,128 - 129,308,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6129,299,127 - 129,308,759 (-)EnsemblGRCm39 Ensembl
GRCm386129,322,165 - 129,331,807 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6129,322,164 - 129,331,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv376129,272,183 - 129,281,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366129,287,857 - 129,297,446 (-)NCBIMGSCv36mm8
Celera6131,044,514 - 131,054,123 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.25NCBI
Klre1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,719,307 - 164,727,664 (+)NCBIGRCr8
mRatBN7.24163,033,581 - 163,041,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4163,033,563 - 163,041,638 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4169,270,513 - 169,276,372 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04165,053,473 - 165,059,328 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,687,521 - 163,693,376 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,346,684 - 163,355,050 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,349,125 - 163,354,976 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,989,389 - 211,997,747 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,857,685 - 166,864,221 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14167,102,620 - 167,109,157 (+)NCBI
Celera4151,715,553 - 151,721,408 (+)NCBICelera
Cytogenetic Map4q42NCBI
LOC102005691
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554137,489,127 - 7,504,956 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554137,489,158 - 7,503,014 (+)NCBIChiLan1.0ChiLan1.0
LOC101976242
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494597,084,874 - 97,099,433 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936902216,495 - 229,141 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936902216,495 - 229,150 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100519314
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1561,724,744 - 61,736,667 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2564,653,296 - 64,665,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLRK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,207,066 - 10,223,922 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,207,211 - 10,223,899 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660892,283,754 - 2,301,143 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC100687968
106 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 4 5 1
Below cutoff 1 1 1 1 1 2 2 1 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003433576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005637167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005637168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038439036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038439037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038439038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038576763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002620201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005303205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005303206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005346325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005346326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005379834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005379835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005413816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005413817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_295875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_003433576   ⟹   XP_003433624
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12736,059,715 - 36,068,092 (+)NCBI
Dog10K_Boxer_Tasha2710,555,689 - 10,564,060 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005637167   ⟹   XP_005637224
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12736,060,178 - 36,068,092 (+)NCBI
Dog10K_Boxer_Tasha2710,555,689 - 10,563,602 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005637168   ⟹   XP_005637225
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12736,059,718 - 36,068,092 (+)NCBI
Dog10K_Boxer_Tasha2710,555,689 - 10,564,057 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038439036   ⟹   XP_038294964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02736,406,103 - 36,414,471 (+)NCBI
RefSeq Acc Id: XM_038439037   ⟹   XP_038294965
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02736,406,566 - 36,414,471 (+)NCBI
RefSeq Acc Id: XM_038439038   ⟹   XP_038294966
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02736,406,106 - 36,414,471 (+)NCBI
RefSeq Acc Id: XM_038513690   ⟹   XP_038369618
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12736,293,169 - 36,301,539 (+)NCBI
RefSeq Acc Id: XM_038513691   ⟹   XP_038369619
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12736,293,633 - 36,301,539 (+)NCBI
RefSeq Acc Id: XM_038513692   ⟹   XP_038369620
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12736,293,172 - 36,301,539 (+)NCBI
RefSeq Acc Id: XM_038576761   ⟹   XP_038432689
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02710,077,763 - 10,086,134 (-)NCBI
RefSeq Acc Id: XM_038576762   ⟹   XP_038432690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02710,077,763 - 10,085,676 (-)NCBI
RefSeq Acc Id: XM_038576763   ⟹   XP_038432691
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02710,077,763 - 10,086,131 (-)NCBI
RefSeq Acc Id: XM_038641519   ⟹   XP_038497447
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02736,316,972 - 36,325,348 (+)NCBI
RefSeq Acc Id: XM_038641520   ⟹   XP_038497448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02736,317,435 - 36,325,348 (+)NCBI
RefSeq Acc Id: XM_038641521   ⟹   XP_038497449
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02736,316,975 - 36,325,348 (+)NCBI
RefSeq Acc Id: XR_002620201
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12736,059,707 - 36,068,092 (+)NCBI
Dog10K_Boxer_Tasha2710,555,689 - 10,564,069 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005303205
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02736,406,101 - 36,414,471 (+)NCBI
RefSeq Acc Id: XR_005303206
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02736,406,096 - 36,414,471 (+)NCBI
RefSeq Acc Id: XR_005346325
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12736,293,167 - 36,301,539 (+)NCBI
RefSeq Acc Id: XR_005346326
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12736,293,162 - 36,301,539 (+)NCBI
RefSeq Acc Id: XR_005379834
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02710,077,763 - 10,086,137 (-)NCBI
RefSeq Acc Id: XR_005379835
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02710,077,763 - 10,086,143 (-)NCBI
RefSeq Acc Id: XR_005413816
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02736,316,970 - 36,325,348 (+)NCBI
RefSeq Acc Id: XR_005413817
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02736,316,965 - 36,325,348 (+)NCBI
RefSeq Acc Id: XR_295875
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12736,059,712 - 36,068,092 (+)NCBI
Dog10K_Boxer_Tasha2710,555,689 - 10,564,062 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003433624   ⟸   XM_003433576
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SJV2 (UniProtKB/TrEMBL),   A0A8I3Q333 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005637225   ⟸   XM_005637168
- Peptide Label: isoform X3
- UniProtKB: A0A8C0SJX5 (UniProtKB/TrEMBL),   A0A8I3PYQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005637224   ⟸   XM_005637167
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_038369618   ⟸   XM_038513690
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038369620   ⟸   XM_038513692
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038369619   ⟸   XM_038513691
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038497447   ⟸   XM_038641519
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038497449   ⟸   XM_038641521
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038497448   ⟸   XM_038641520
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038294964   ⟸   XM_038439036
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SJV2 (UniProtKB/TrEMBL),   A0A8I3Q333 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038294966   ⟸   XM_038439038
- Peptide Label: isoform X3
- UniProtKB: A0A8C0SJX5 (UniProtKB/TrEMBL),   A0A8I3PYQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038294965   ⟸   XM_038439037
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038432689   ⟸   XM_038576761
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SJV2 (UniProtKB/TrEMBL),   A0A8I3Q333 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432691   ⟸   XM_038576763
- Peptide Label: isoform X3
- UniProtKB: A0A8C0SJX5 (UniProtKB/TrEMBL),   A0A8I3PYQ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432690   ⟸   XM_038576762
- Peptide Label: isoform X2
Protein Domains
C-type lectin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029262 UniProtKB/TrEMBL
  ENSCAFG00040013809 UniProtKB/TrEMBL
  ENSCAFG00845027591 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000042838.3 UniProtKB/TrEMBL
  ENSCAFT00000107058.1 UniProtKB/TrEMBL
  ENSCAFT00040025457.1 UniProtKB/TrEMBL
  ENSCAFT00040025482.1 UniProtKB/TrEMBL
  ENSCAFT00845048643 ENTREZGENE
  ENSCAFT00845048643.1 UniProtKB/TrEMBL
  ENSCAFT00845048667 ENTREZGENE
  ENSCAFT00845048667.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/TrEMBL
  CTDL_fold UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/TrEMBL
KEGG Report cfa:100687968 UniProtKB/TrEMBL
NCBI Gene LOC100687968 ENTREZGENE
PANTHER C-TYPE LECTIN DOMAIN FAMILY 2, MEMBER M UniProtKB/TrEMBL
  C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_2 UniProtKB/TrEMBL
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/TrEMBL
UniProt A0A8C0SJV2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SJX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PYQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q333 ENTREZGENE, UniProtKB/TrEMBL