CARTPT (CART prepropeptide) - Rat Genome Database

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Gene: CARTPT (CART prepropeptide) Canis lupus familiaris
Analyze
Symbol: CARTPT
Name: CART prepropeptide
RGD ID: 12423485
Description: ENCODES a protein that exhibits neuropeptide hormone activity (inferred); INVOLVED IN circadian regulation of gene expression (ortholog); negative regulation of glucagon secretion (ortholog); positive regulation of MAPK cascade (ortholog); ASSOCIATED WITH Alcohol-Related Disorders (ortholog); anxiety disorder (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); secretory granule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cocaine- and amphetamine-regulated transcript protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,865,043 - 54,867,410 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl254,865,298 - 54,867,158 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,831,747 - 51,833,904 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0255,380,658 - 55,382,812 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl255,380,662 - 55,382,560 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1252,441,398 - 52,443,555 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0253,208,304 - 53,210,460 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0254,099,675 - 54,101,833 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CARTPT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,865,043 - 54,867,410 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl254,865,298 - 54,867,158 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,831,747 - 51,833,904 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0255,380,658 - 55,382,812 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl255,380,662 - 55,382,560 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1252,441,398 - 52,443,555 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0253,208,304 - 53,210,460 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0254,099,675 - 54,101,833 (+)NCBIUU_Cfam_GSD_1.0
CARTPT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38571,719,275 - 71,721,045 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl571,719,275 - 71,721,048 (+)EnsemblGRCh38hg38GRCh38
GRCh37571,015,102 - 71,016,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36571,050,750 - 71,052,628 (+)NCBINCBI36Build 36hg18NCBI36
Celera566,910,678 - 66,912,563 (+)NCBICelera
Cytogenetic Map5q13.2NCBI
HuRef566,220,931 - 66,222,816 (+)NCBIHuRef
CHM1_1570,447,686 - 70,449,571 (+)NCBICHM1_1
T2T-CHM13v2.0572,200,597 - 72,202,367 (+)NCBIT2T-CHM13v2.0
Cartpt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913100,034,991 - 100,037,191 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13100,034,997 - 100,037,599 (-)EnsemblGRCm39 Ensembl
GRCm381399,898,483 - 99,910,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1399,898,489 - 99,901,091 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713100,668,439 - 100,670,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613100,998,914 - 101,000,892 (-)NCBIMGSCv36mm8
Celera13103,550,272 - 103,552,922 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1352.9NCBI
Cartpt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8232,989,215 - 32,991,794 (-)NCBIGRCr8
mRatBN7.2231,255,098 - 31,257,452 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl231,255,098 - 31,290,713 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx238,333,324 - 38,335,346 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0236,427,667 - 36,429,691 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0231,220,463 - 31,222,481 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0230,125,249 - 30,127,408 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,125,249 - 30,127,269 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0249,285,118 - 49,287,405 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4230,889,817 - 30,891,837 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1230,810,185 - 30,812,206 (-)NCBI
Celera227,276,402 - 27,278,422 (-)NCBICelera
Cytogenetic Map2q12NCBI
Cartpt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955575551,991 - 555,149 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955575551,991 - 555,118 (+)NCBIChiLan1.0ChiLan1.0
CARTPT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2443,593,184 - 43,595,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1541,746,812 - 41,748,989 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0543,591,683 - 43,593,586 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1544,236,114 - 44,238,229 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl544,236,114 - 44,238,229 (-)Ensemblpanpan1.1panPan2
Cartpt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213186,139,406 - 186,141,636 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365494,717,771 - 4,719,395 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365494,717,337 - 4,719,523 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CARTPT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1648,043,492 - 48,045,592 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11648,043,558 - 48,045,592 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21651,989,808 - 51,991,843 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CARTPT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1466,058,755 - 66,060,635 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl466,058,769 - 66,061,112 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604914,805,312 - 14,807,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cartpt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624905751,223 - 752,845 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624905751,032 - 753,012 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CARTPT
35 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 2
Medium 9 6
Low 1 1 1 1 6
Below cutoff 4 5 10 5 6 5 6 6 8 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000048241   ⟹   ENSCAFP00000037352
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl254,865,298 - 54,867,158 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845000326   ⟹   ENSCAFP00845000228
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl255,380,662 - 55,382,560 (+)Ensembl
RefSeq Acc Id: XM_038469996   ⟹   XP_038325924
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1252,441,398 - 52,443,555 (+)NCBI
RefSeq Acc Id: XM_038530802   ⟹   XP_038386730
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0254,099,675 - 54,101,833 (+)NCBI
RefSeq Acc Id: XM_038595021   ⟹   XP_038450949
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0253,208,304 - 53,210,460 (+)NCBI
RefSeq Acc Id: XM_038659100   ⟹   XP_038515028
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0255,380,658 - 55,382,812 (+)NCBI
RefSeq Acc Id: XM_847679   ⟹   XP_852772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1254,865,043 - 54,867,410 (+)NCBI
Dog10K_Boxer_Tasha251,831,747 - 51,833,904 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_852772   ⟸   XM_847679
- UniProtKB: A0A8C0QHC6 (UniProtKB/TrEMBL),   A0A8I3MHA3 (UniProtKB/TrEMBL),   A0A8C0KYR9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037352   ⟸   ENSCAFT00000048241
RefSeq Acc Id: XP_038325924   ⟸   XM_038469996
RefSeq Acc Id: XP_038450949   ⟸   XM_038595021
RefSeq Acc Id: XP_038515028   ⟸   XM_038659100
- UniProtKB: A0A8C0QHC6 (UniProtKB/TrEMBL),   A0A8I3MHA3 (UniProtKB/TrEMBL),   A0A8C0KYR9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386730   ⟸   XM_038530802
- UniProtKB: A0A8C0KYR9 (UniProtKB/TrEMBL),   A0A8C0QHC6 (UniProtKB/TrEMBL),   A0A8I3MHA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845000228   ⟸   ENSCAFT00845000326

Promoters
RGD ID:13682495
Promoter ID:EPDNEW_C564
Type:single initiation site
Name:CARTPT_1
Description:CART prepropeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1254,864,847 - 54,864,907EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031950 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004564 UniProtKB/TrEMBL
  ENSCAFG00040005419 UniProtKB/TrEMBL
  ENSCAFG00845000216 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048241.3 UniProtKB/TrEMBL
  ENSCAFT00030008391.1 UniProtKB/TrEMBL
  ENSCAFT00040010180.1 UniProtKB/TrEMBL
  ENSCAFT00845000326 ENTREZGENE
  ENSCAFT00845000326.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.40.30 UniProtKB/TrEMBL
InterPro CART UniProtKB/TrEMBL
  CART_C_sf UniProtKB/TrEMBL
KEGG Report cfa:610236 UniProtKB/TrEMBL
NCBI Gene CARTPT ENTREZGENE
PANTHER COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN UniProtKB/TrEMBL
  PTHR16655 UniProtKB/TrEMBL
Pfam CART UniProtKB/TrEMBL
Superfamily-SCOP SSF64546 UniProtKB/TrEMBL
UniProt A0A8C0KYR9 ENTREZGENE
  A0A8C0QHC6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHA3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SSG8_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38727 ENTREZGENE