FSD1 (fibronectin type III and SPRY domain containing 1) - Rat Genome Database

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Gene: FSD1 (fibronectin type III and SPRY domain containing 1) Canis lupus familiaris
Analyze
Symbol: FSD1
Name: fibronectin type III and SPRY domain containing 1
RGD ID: 12423077
Description: ENCODES a protein that exhibits identical protein binding (inferred); microtubule binding (inferred); INVOLVED IN cell division (inferred); cytoplasmic microtubule organization (inferred); regulation of cell division (inferred); ASSOCIATED WITH amenorrhea (ortholog); genetic disease (ortholog); Stomach Neoplasms (ortholog); FOUND IN centrosome (inferred); cleavage furrow (inferred); microtubule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibronectin type III and SPRY domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,333,937 - 55,344,861 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,333,785 - 55,344,843 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,062,100 - 55,080,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,993,017 - 56,011,507 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,993,071 - 56,004,636 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,053,501 - 55,071,720 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,534,443 - 55,552,704 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,733,089 - 55,751,345 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FSD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,333,937 - 55,344,861 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,333,785 - 55,344,843 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,062,100 - 55,080,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,993,017 - 56,011,507 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,993,071 - 56,004,636 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,053,501 - 55,071,720 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,534,443 - 55,552,704 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,733,089 - 55,751,345 (-)NCBIUU_Cfam_GSD_1.0
FSD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,304,598 - 4,323,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,304,598 - 4,323,843 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,304,595 - 4,323,833 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,255,691 - 4,274,838 (+)NCBINCBI36Build 36hg18NCBI36
Build 34194,255,690 - 4,274,838NCBI
Celera19627,256 - 628,117 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,068,531 - 4,086,554 (+)NCBIHuRef
CHM1_1194,304,209 - 4,323,460 (+)NCBICHM1_1
T2T-CHM13v2.0194,287,878 - 4,307,238 (+)NCBIT2T-CHM13v2.0
Fsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,293,475 - 56,303,881 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,293,509 - 56,303,881 (+)EnsemblGRCm39 Ensembl
GRCm381755,986,462 - 55,996,883 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1755,986,509 - 55,996,881 (+)EnsemblGRCm38mm10GRCm38
MGSCv371756,125,934 - 56,136,304 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,579,804 - 55,590,174 (+)NCBIMGSCv36mm8
Celera1759,405,038 - 59,415,407 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.1NCBI
Fsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89905,418 - 908,938 (+)NCBIGRCr8
mRatBN7.29818,241 - 821,761 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9818,263 - 828,185 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,265,272 - 1,268,793 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,612,522 - 6,616,042 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,570,304 - 5,573,825 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,076,670 - 11,080,190 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,067,369 - 11,080,155 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,061,938 - 10,065,458 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,684,706 - 7,688,226 (-)NCBICelera
Cytogenetic Map9q11NCBI
Fsd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,549,220 - 4,561,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,549,067 - 4,561,223 (-)NCBIChiLan1.0ChiLan1.0
FSD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,701,598 - 8,722,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,931,823 - 7,951,570 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,327,681 - 3,347,176 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,274,389 - 4,294,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,274,389 - 4,294,179 (+)Ensemblpanpan1.1panPan2
Fsd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,365,410 - 215,373,017 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,461,411 - 2,469,507 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,461,582 - 2,469,373 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,471,744 - 74,485,786 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,471,744 - 74,485,788 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,964,692 - 74,978,738 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FSD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,042,375 - 4,059,579 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl64,042,500 - 4,059,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,150,841 - 4,166,902 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fsd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,344,068 - 5,359,906 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,347,861 - 5,359,825 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FSD1
190 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 5 14 6 6 8 8 2
Below cutoff 5 8 6 6 6 5 2 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000030327   ⟹   ENSCAFP00000028175
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2055,333,976 - 55,344,843 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000064271   ⟹   ENSCAFP00000059258
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2055,333,785 - 55,344,843 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845027128   ⟹   ENSCAFP00845021349
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2055,993,071 - 56,004,636 (-)Ensembl
RefSeq Acc Id: XM_038429067   ⟹   XP_038284995
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02055,993,017 - 56,011,507 (-)NCBI
RefSeq Acc Id: XM_038429068   ⟹   XP_038284996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02055,993,017 - 56,011,507 (-)NCBI
RefSeq Acc Id: XM_038455727   ⟹   XP_038311655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2055,062,100 - 55,080,355 (-)NCBI
RefSeq Acc Id: XM_038455728   ⟹   XP_038311656
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2055,062,100 - 55,080,355 (-)NCBI
RefSeq Acc Id: XM_038504651   ⟹   XP_038360579
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12055,053,501 - 55,071,720 (-)NCBI
RefSeq Acc Id: XM_038504652   ⟹   XP_038360580
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12055,053,501 - 55,071,720 (-)NCBI
RefSeq Acc Id: XM_038567744   ⟹   XP_038423672
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02055,733,089 - 55,751,345 (-)NCBI
RefSeq Acc Id: XM_038631875   ⟹   XP_038487803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02055,534,443 - 55,552,704 (-)NCBI
RefSeq Acc Id: XM_038631876   ⟹   XP_038487804
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02055,534,443 - 55,552,704 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000028175   ⟸   ENSCAFT00000030327
RefSeq Acc Id: ENSCAFP00000059258   ⟸   ENSCAFT00000064271
RefSeq Acc Id: XP_038360580   ⟸   XM_038504652
RefSeq Acc Id: XP_038360579   ⟸   XM_038504651
RefSeq Acc Id: XP_038487804   ⟸   XM_038631876
RefSeq Acc Id: XP_038487803   ⟸   XM_038631875
RefSeq Acc Id: XP_038284996   ⟸   XM_038429068
- UniProtKB: A0A8C0L499 (UniProtKB/TrEMBL),   A0A8C0M8S7 (UniProtKB/TrEMBL),   A0A8I3S1C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038284995   ⟸   XM_038429067
- UniProtKB: A0A8C0L499 (UniProtKB/TrEMBL),   A0A8C0M8S7 (UniProtKB/TrEMBL),   A0A8I3S1C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311656   ⟸   XM_038455728
- UniProtKB: A0A8C0L499 (UniProtKB/TrEMBL),   A0A8C0M8S7 (UniProtKB/TrEMBL),   A0A8I3S1C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311655   ⟸   XM_038455727
- UniProtKB: A0A8C0L499 (UniProtKB/TrEMBL),   A0A8C0M8S7 (UniProtKB/TrEMBL),   A0A8I3S1C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423672   ⟸   XM_038567744
- UniProtKB: A0A8C0L499 (UniProtKB/TrEMBL),   A0A8C0M8S7 (UniProtKB/TrEMBL),   A0A8I3S1C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845021349   ⟸   ENSCAFT00845027128
Protein Domains
B30.2/SPRY   COS   Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019098 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003982 UniProtKB/TrEMBL
  ENSCAFG00040006303 UniProtKB/TrEMBL
  ENSCAFG00845015189 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000030327.5 UniProtKB/TrEMBL
  ENSCAFT00030007368.1 UniProtKB/TrEMBL
  ENSCAFT00040011758.1 UniProtKB/TrEMBL
  ENSCAFT00845027128 ENTREZGENE
  ENSCAFT00845027128.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  2.60.120.920 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Bbox_C UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  COS_domain UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  SPRY/PRY_FSD1 UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
NCBI Gene FSD1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED UniProtKB/TrEMBL
  FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  COS UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A8C0L499 ENTREZGENE
  A0A8C0M8S7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S1C1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40993 ENTREZGENE