KIF3A (kinesin family member 3A) - Rat Genome Database

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Gene: KIF3A (kinesin family member 3A) Canis lupus familiaris
Analyze
Symbol: KIF3A
Name: kinesin family member 3A
RGD ID: 12422207
Description: ENCODES a protein that exhibits intraciliary transport particle B binding (ortholog); kinesin binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); centriole-centriole cohesion (ortholog); cilium assembly (ortholog); PARTICIPATES IN Hedgehog signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH asthma (ortholog); bone development disease (ortholog); COVID-19 (ortholog); FOUND IN axon cytoplasm (ortholog); axoneme (ortholog); centriole (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinesin-like protein KIF3A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,988,516 - 21,044,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,928,655 - 21,044,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBI
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBI
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)Ensembl
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBI
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBI
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:11912492   PMID:23658710   PMID:34753064  


Genomics

Comparative Map Data
KIF3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,988,516 - 21,044,151 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,928,655 - 21,044,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBI
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBI
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)Ensembl
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBI
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBI
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBI
KIF3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,688,812 - 132,737,546 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5132,692,628 - 132,737,638 (-)EnsemblGRCh38hg38GRCh38
GRCh375132,028,323 - 132,073,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,056,222 - 132,101,164 (-)NCBINCBI36hg18NCBI36
Build 345132,059,220 - 132,101,163NCBI
Celera5128,158,460 - 128,203,363 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,220,971 - 127,265,873 (-)NCBIHuRef
CHM1_15131,461,606 - 131,506,536 (-)NCBICHM1_1
T2T-CHM13v2.05133,212,401 - 133,257,281 (-)NCBI
Kif3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,456,531 - 53,495,075 (+)NCBIGRCm39mm39
GRCm39 Ensembl1153,458,206 - 53,492,794 (+)Ensembl
GRCm381153,565,701 - 53,604,248 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,567,379 - 53,601,967 (+)EnsemblGRCm38mm10GRCm38
MGSCv371153,380,881 - 53,417,746 (+)NCBIGRCm37mm9NCBIm37
MGSCv361153,410,826 - 53,445,377 (+)NCBImm8
Celera1158,146,946 - 58,183,772 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.97NCBI
Kif3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21037,725,930 - 37,761,183 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1037,725,970 - 37,759,191 (+)Ensembl
Rnor_6.01038,918,705 - 38,953,958 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,918,748 - 38,952,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,700,206 - 38,734,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,029,351 - 39,062,570 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,057,446 - 39,068,547 (+)NCBI
Celera1037,070,450 - 37,103,611 (+)NCBICelera
Cytogenetic Map10q22NCBI
Kif3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554084,069,639 - 4,115,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554084,072,823 - 4,115,975 (-)NCBIChiLan1.0ChiLan1.0
KIF3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15134,268,505 - 134,315,431 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,274,352 - 134,315,431 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05128,112,636 - 128,154,443 (-)NCBIMhudiblu_PPA_v0panPan3
Kif3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,458,121 - 115,499,788 (+)NCBI
SpeTri2.0NW_0049366472,461,017 - 2,502,550 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,932,615 - 135,069,351 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,932,339 - 135,069,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,400,867 - 140,537,919 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KIF3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,496,770 - 35,554,536 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,514,130 - 35,551,472 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603442,387,830 - 42,436,606 (+)NCBIVero_WHO_p1.0
Kif3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,354,232 - 39,407,121 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473339,354,360 - 39,406,574 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8 12 8 2
Low 5 5 13 5 6 5 6 6 8 6
Below cutoff 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022425273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022425274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038490053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038552133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038615991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038615992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038615993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038681489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_855769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000001398   ⟹   ENSCAFP00000001284
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1120,991,688 - 21,044,090 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000001399   ⟹   ENSCAFP00000001285
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1120,991,688 - 21,044,090 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000001401   ⟹   ENSCAFP00000001287
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1120,928,655 - 21,044,090 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000086835   ⟹   ENSCAFP00000054706
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1120,959,550 - 21,044,090 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845019570   ⟹   ENSCAFP00845015306
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845019648   ⟹   ENSCAFP00845015370
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845019723   ⟹   ENSCAFP00845015436
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1121,774,475 - 21,830,123 (-)Ensembl
RefSeq Acc Id: XM_022425273   ⟹   XP_022280981
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11120,988,516 - 21,044,151 (-)NCBI
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022425274   ⟹   XP_022280982
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11120,988,516 - 21,044,151 (-)NCBI
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038490051   ⟹   XP_038345979
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBI
RefSeq Acc Id: XM_038490052   ⟹   XP_038345980
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBI
RefSeq Acc Id: XM_038490053   ⟹   XP_038345981
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11120,492,965 - 20,548,637 (-)NCBI
RefSeq Acc Id: XM_038552131   ⟹   XP_038408059
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBI
RefSeq Acc Id: XM_038552132   ⟹   XP_038408060
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBI
RefSeq Acc Id: XM_038552133   ⟹   XP_038408061
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01120,983,018 - 21,038,700 (-)NCBI
RefSeq Acc Id: XM_038615991   ⟹   XP_038471919
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBI
RefSeq Acc Id: XM_038615992   ⟹   XP_038471920
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBI
RefSeq Acc Id: XM_038615993   ⟹   XP_038471921
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01120,340,508 - 20,396,333 (-)NCBI
RefSeq Acc Id: XM_038681487   ⟹   XP_038537415
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBI
RefSeq Acc Id: XM_038681488   ⟹   XP_038537416
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBI
RefSeq Acc Id: XM_038681489   ⟹   XP_038537417
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01121,774,466 - 21,830,159 (-)NCBI
RefSeq Acc Id: XM_855769   ⟹   XP_860862
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11120,988,516 - 21,044,151 (-)NCBI
Dog10K_Boxer_Tasha1119,790,183 - 19,845,775 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_860862   ⟸   XM_855769
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022280982   ⟸   XM_022425274
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022280981   ⟸   XM_022425273
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000001287   ⟸   ENSCAFT00000001401
RefSeq Acc Id: ENSCAFP00000001285   ⟸   ENSCAFT00000001399
RefSeq Acc Id: ENSCAFP00000001284   ⟸   ENSCAFT00000001398
RefSeq Acc Id: ENSCAFP00000054706   ⟸   ENSCAFT00000086835
RefSeq Acc Id: XP_038345981   ⟸   XM_038490053
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038345980   ⟸   XM_038490052
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038345979   ⟸   XM_038490051
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038471921   ⟸   XM_038615993
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038471920   ⟸   XM_038615992
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038471919   ⟸   XM_038615991
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038537417   ⟸   XM_038681489
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038537416   ⟸   XM_038681488
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038537415   ⟸   XM_038681487
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038408061   ⟸   XM_038552133
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038408060   ⟸   XM_038552132
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038408059   ⟸   XM_038552131
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845015306   ⟸   ENSCAFT00845019570
RefSeq Acc Id: ENSCAFP00845015436   ⟸   ENSCAFT00845019723
RefSeq Acc Id: ENSCAFP00845015370   ⟸   ENSCAFT00845019648
Protein Domains
Kinesin motor

Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 21007242 21007243 C T snv Border Collie (BC555)
11 21029345 21029346 G T snv Dachshund (DH0117), Berger Blanc Suisse (BB011), Bearded Collie (BD093)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000000898 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030011399 UniProtKB/TrEMBL
  ENSCAFG00040006388 UniProtKB/TrEMBL
  ENSCAFG00845011039 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000001284 UniProtKB/TrEMBL
  ENSCAFP00000001285 UniProtKB/TrEMBL
  ENSCAFP00000001287 UniProtKB/TrEMBL
  ENSCAFP00000054706 UniProtKB/TrEMBL
  ENSCAFP00030018464 UniProtKB/TrEMBL
  ENSCAFP00030018523 UniProtKB/TrEMBL
  ENSCAFP00030018553 UniProtKB/TrEMBL
  ENSCAFP00040010357 UniProtKB/TrEMBL
  ENSCAFP00040010383 UniProtKB/TrEMBL
  ENSCAFP00040010427 UniProtKB/TrEMBL
  ENSCAFP00845015306 ENTREZGENE
  ENSCAFP00845015370 ENTREZGENE
  ENSCAFP00845015436 ENTREZGENE
Ensembl Transcript ENSCAFT00000001398 UniProtKB/TrEMBL
  ENSCAFT00000001399 UniProtKB/TrEMBL
  ENSCAFT00000001401 UniProtKB/TrEMBL
  ENSCAFT00000086835 UniProtKB/TrEMBL
  ENSCAFT00030021173 UniProtKB/TrEMBL
  ENSCAFT00030021253 UniProtKB/TrEMBL
  ENSCAFT00030021284 UniProtKB/TrEMBL
  ENSCAFT00040011947 UniProtKB/TrEMBL
  ENSCAFT00040011977 UniProtKB/TrEMBL
  ENSCAFT00040012030 UniProtKB/TrEMBL
  ENSCAFT00845019570 ENTREZGENE
  ENSCAFT00845019648 ENTREZGENE
  ENSCAFT00845019723 ENTREZGENE
Gene3D-CATH 3.40.850.10 UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene KIF3A ENTREZGENE
PANTHER PTHR24115 UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/TrEMBL
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A5F4CMR7_CANLF UniProtKB/TrEMBL
  A0A8C0MXT1_CANLF UniProtKB/TrEMBL
  A0A8C0MY02_CANLF UniProtKB/TrEMBL
  A0A8C0QA29_CANLF UniProtKB/TrEMBL
  F1PQE6_CANLF UniProtKB/TrEMBL
  F1PSQ4_CANLF UniProtKB/TrEMBL
  F6UP44_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:42404 ENTREZGENE