LOC100686047 (protein CD300H-like)

Gene: LOC100686047 (protein CD300H-like) Canis lupus familiaris

Analyze

Symbol:

LOC100686047 (Ensembl: CD300H)

Name:

protein CD300H-like

RGD ID:

12422065

Description:

ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN neutrophil chemotaxis (ortholog); FOUND IN extracellular region (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

CMRF35-like molecule

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	5,865,272 - 5,894,005 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	5,865,075 - 5,894,005 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	6,511,107 - 6,515,653 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	6,537,131 - 6,565,854 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	6,536,896 - 6,565,851 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	6,578,101 - 6,606,805 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	6,681,564 - 6,710,313 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	6,741,420 - 6,770,165 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

neutrophil chemotaxis (ISO)

Cellular Component

extracellular region (ISO)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

protein binding (ISO)

protein homodimerization activity (ISO)

transmembrane signaling receptor activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LOC100686047
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	5,865,272 - 5,894,005 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	5,865,075 - 5,894,005 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	6,511,107 - 6,515,653 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	6,537,131 - 6,565,854 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	6,536,896 - 6,565,851 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	6,578,101 - 6,606,805 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	6,681,564 - 6,710,313 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	6,741,420 - 6,770,165 (+)	NCBI		UU_Cfam_GSD_1.0

CD300H
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	74,557,243 - 74,567,509 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	74,560,701 - 74,567,343 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	72,556,840 - 72,563,648 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	70,067,905 - 70,077,575 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	69,148,800 - 69,155,923 (-)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	67,965,947 - 67,972,896 (-)	NCBI		HuRef
CHM1_1	17	72,621,249 - 72,628,031 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	75,447,764 - 75,458,030 (-)	NCBI		T2T-CHM13v2.0

CD300H
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	90,597,806 - 90,605,222 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	95,420,794 - 95,428,217 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	68,506,702 - 68,513,783 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	74,063,581 - 74,070,086 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	74,063,581 - 74,070,086 (-)	Ensembl	panpan1.1		panPan2

CD300H
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	12	6,620,403 - 6,630,163 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	6,609,265 - 6,619,177 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103243085
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	47,083,784 - 47,094,856 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666556	6,857 - 13,883 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in LOC100686047
423 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium					2
Low					4		3				5	1
Below cutoff	5	5	22	6		6	3	6	12	6	5	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003435168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022422740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038484990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038484991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038546677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038546678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038610668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038610669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038675798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038675799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000049895 ⟹ ENSCAFP00000038234

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	5,865,075 - 5,894,005 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000059801 ⟹ ENSCAFP00000055387

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	5,888,867 - 5,894,005 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032239 ⟹ ENSCAFP00845025202

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	9	6,536,896 - 6,565,851 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032271 ⟹ ENSCAFP00845025227

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	9	6,561,351 - 6,565,851 (+)	Ensembl

RefSeq Acc Id:

XM_003435168 ⟹ XP_003435216

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	5,889,479 - 5,894,005 (+)	NCBI
Dog10K_Boxer_Tasha	9	6,511,107 - 6,515,653 (+)	NCBI

Sequence:

show sequence

ACAGTGAGGGCATCCTCTTCATAGGAAACAGAAAAAAGAACTGTGCATTGAGATGTGTTTCTGA
GGATGAACTTTAGCAAATCCTCAGTGAACCACATGATGCCCTGAGCCCCTCACTTCCCCCATTT
TCTGAGCAACTCTGAGAACAGAACCAAGAGGCTGAAGAAGGAAGCAGAGAAATGCCAAGAAAAG
CAGAGGAGGGAGACAGGCTGAGCGGCCCCTGGGTGAGGAGTGTTCCAGCTGCAGCTGGAGAGAC
AGCAGAGGGACGGGACCATGTGGCTGCCATCAGCTCTGCTGCTCCTCTGCGTCCCAGGCTGTTC
ATCTCTGAGTGGTCCCAGCACTGCGATGGGCACCATTGGGGGATCCCTGAGCGTGCAGTGTCGG
TATGAGGAGAAATACAAGACATTTACTAAATACTGGTGCCGACAACCATGCTTGTTCCTTTGGA
ACCAGATTGTGGCCACCAGAGAGTCTGAGGAAGAAGTGAGGAGTGACCATGTGTCCATCGTGGA
CCATTCTGGGGACCTCACCTTCACTGTGACCTTGGAGAACCTCACTGCAGATGATGCAGGAAAA
TATAGGTGTGGGATTGCGACAATATTGCATGAAGAGGGACTCCTTGGCTTCCTGCCTGACCTCT
TTTTCCAAGTTCAAGTGTTTGTTTCCCCCAGGTCCCTGCCTGGCAGTGTCCACTTCCTGCTCCT
CATACTCGTGAAGGTGCCCCTGTTTCTGACTATGCTAAGTGCTGTCCTCTGGGTGAACAGGCCT
CAGTGGGCAGTTTGTGGGAAACAGAGTCGACCTGATGAAGACAACAATATCTTGTCCTGAAGAT
ACCGCCACTCAGACTAAAGAAGGAGGAACTTCTGGCCTCAAACCTTCTATTTCTTCTCACCTTA
TTGCCAAAAACTGGTATTAAAAAAAAAGTAATGAAATATATCACACACACAAGTGCAAA

hide sequence

RefSeq Acc Id:

XM_038484990 ⟹ XP_038340918

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	9	6,602,255 - 6,606,805 (+)	NCBI

RefSeq Acc Id:

XM_038484991 ⟹ XP_038340919

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	9	6,578,101 - 6,606,805 (+)	NCBI

RefSeq Acc Id:

XM_038546677 ⟹ XP_038402605

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	9	6,765,612 - 6,770,165 (+)	NCBI

RefSeq Acc Id:

XM_038546678 ⟹ XP_038402606

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	9	6,741,420 - 6,770,165 (+)	NCBI

RefSeq Acc Id:

XM_038610668 ⟹ XP_038466596

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	9	6,705,756 - 6,710,313 (+)	NCBI

RefSeq Acc Id:

XM_038610669 ⟹ XP_038466597

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	9	6,681,564 - 6,710,313 (+)	NCBI

RefSeq Acc Id:

XM_038675798 ⟹ XP_038531726

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	9	6,561,302 - 6,565,854 (+)	NCBI

RefSeq Acc Id:

XM_038675799 ⟹ XP_038531727

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	9	6,537,131 - 6,565,854 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003435216	(Get FASTA)	NCBI Sequence Viewer
	XP_038340918	(Get FASTA)	NCBI Sequence Viewer
	XP_038340919	(Get FASTA)	NCBI Sequence Viewer
	XP_038402605	(Get FASTA)	NCBI Sequence Viewer
	XP_038402606	(Get FASTA)	NCBI Sequence Viewer
	XP_038466596	(Get FASTA)	NCBI Sequence Viewer
	XP_038466597	(Get FASTA)	NCBI Sequence Viewer
	XP_038531726	(Get FASTA)	NCBI Sequence Viewer
	XP_038531727	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000038234.1
	ENSCAFP00845025202
	ENSCAFP00845025202.1
	ENSCAFP00845025227
	ENSCAFP00845025227.1

RefSeq Acc Id:	XP_003435216 ⟸ XM_003435168
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3P6K8 (UniProtKB/TrEMBL), A0A8P0NPY4 (UniProtKB/TrEMBL), A0A8C0L6Q5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWLPSALLLLCVPGCSSLSGPSTAMGTIGGSLSVQCRYEEKYKTFTKYWCRQPCLFLWNQIVAT RESEEEVRSDHVSIVDHSGDLTFTVTLENLTADDAGKYRCGIATILHEEGLLGFLPDLFFQVQV FVSPRSLPGSVHFLLLILVKVPLFLTMLSAVLWVNRPQWAVCGKQSRPDEDNNILS hide sequence

RefSeq Acc Id:

ENSCAFP00000038234 ⟸ ENSCAFT00000049895

RefSeq Acc Id:

ENSCAFP00000055387 ⟸ ENSCAFT00000059801

RefSeq Acc Id:	XP_038340919 ⟸ XM_038484991
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038340918 ⟸ XM_038484990
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038466597 ⟸ XM_038610669
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038466596 ⟸ XM_038610668
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038531727 ⟸ XM_038675799
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3P6K8 (UniProtKB/TrEMBL), A0A8P0NPY4 (UniProtKB/TrEMBL), A0A8C0L6Q5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038531726 ⟸ XM_038675798
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3P6K8 (UniProtKB/TrEMBL), A0A8P0NPY4 (UniProtKB/TrEMBL), A0A8C0L6Q5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038402606 ⟸ XM_038546678
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0L6Q5 (UniProtKB/TrEMBL), A0A8I3P6K8 (UniProtKB/TrEMBL), A0A8P0NPY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038402605 ⟸ XM_038546677
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0L6Q5 (UniProtKB/TrEMBL), A0A8I3P6K8 (UniProtKB/TrEMBL), A0A8P0NPY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845025227 ⟸ ENSCAFT00845032271

RefSeq Acc Id:

ENSCAFP00845025202 ⟸ ENSCAFT00845032239

Protein Domains

Ig-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000028912	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00845018232	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000049895.3	UniProtKB/TrEMBL
	ENSCAFT00845032239	ENTREZGENE
	ENSCAFT00845032239.1	UniProtKB/TrEMBL
	ENSCAFT00845032271	ENTREZGENE
	ENSCAFT00845032271.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
KEGG Report	cfa:100686047	UniProtKB/TrEMBL
NCBI Gene	LOC100686047	ENTREZGENE
PANTHER	POLYMERIC-IMMUNOGLOBULIN RECEPTOR	UniProtKB/TrEMBL
	PROTEIN CD300H	UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
SMART	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8C0L6Q5	ENTREZGENE
	A0A8I3P6K8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NPY4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-12	LOC100686047	protein CD300H-like	LOC100686047	CMRF35-like molecule	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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