NECAB2 (N-terminal EF-hand calcium binding protein 2) - Rat Genome Database

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Gene: NECAB2 (N-terminal EF-hand calcium binding protein 2) Canis lupus familiaris
Analyze
Symbol: NECAB2
Name: N-terminal EF-hand calcium binding protein 2
RGD ID: 12417259
Description: ENCODES a protein that exhibits A2A adenosine receptor binding (ortholog); identical protein binding (ortholog); type 5 metabotropic glutamate receptor binding (ortholog); INVOLVED IN negative regulation of G protein-coupled receptor internalization (ortholog); positive regulation of adenosine receptor signaling pathway (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); ASSOCIATED WITH persistent fetal circulation syndrome (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: EF-hand calcium binding protein 2; EFCBP2; N-terminal EF-hand calcium-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,313,699 - 68,342,253 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl568,314,000 - 68,378,311 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,327,774 - 68,357,105 (-)NCBI
ROS_Cfam_1.0568,612,120 - 68,641,500 (-)NCBI
UMICH_Zoey_3.1568,559,839 - 68,589,193 (-)NCBI
UNSW_CanFamBas_1.0568,396,250 - 68,425,583 (-)NCBI
UU_Cfam_GSD_1.0568,812,005 - 68,841,393 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
NECAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,313,699 - 68,342,253 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl568,314,000 - 68,378,311 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,327,774 - 68,357,105 (-)NCBI
ROS_Cfam_1.0568,612,120 - 68,641,500 (-)NCBI
UMICH_Zoey_3.1568,559,839 - 68,589,193 (-)NCBI
UNSW_CanFamBas_1.0568,396,250 - 68,425,583 (-)NCBI
UU_Cfam_GSD_1.0568,812,005 - 68,841,393 (-)NCBI
NECAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1683,968,244 - 84,002,776 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1683,968,632 - 84,002,776 (+)EnsemblGRCh38hg38GRCh38
GRCh381683,968,244 - 84,002,776 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371684,001,849 - 84,036,381 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,559,738 - 82,593,880 (+)NCBINCBI36hg18NCBI36
Build 341682,559,737 - 82,593,878NCBI
Celera1668,304,639 - 68,338,784 (+)NCBI
Cytogenetic Map16q23.3NCBI
HuRef1669,754,045 - 69,790,327 (+)NCBIHuRef
CHM1_11685,413,645 - 85,447,739 (+)NCBICHM1_1
Necab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,173,431 - 120,199,379 (+)NCBIGRCm39mm39
GRCm39 Ensembl8120,173,458 - 120,199,379 (+)Ensembl
GRCm388119,446,719 - 119,472,640 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,446,719 - 119,472,640 (+)EnsemblGRCm38mm10GRCm38
MGSCv378121,970,619 - 121,996,535 (+)NCBIGRCm37mm9NCBIm37
MGSCv368122,332,696 - 122,358,612 (+)NCBImm8
Celera8123,664,580 - 123,689,964 (+)NCBICelera
Cytogenetic Map8E1NCBI
Necab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21947,501,351 - 47,527,722 (+)NCBI
Rnor_6.0 Ensembl1952,086,325 - 52,112,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01952,086,325 - 52,112,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01962,834,865 - 62,861,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,691,466 - 49,718,718 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11949,696,347 - 49,723,599 (+)NCBI
Celera1946,743,032 - 46,786,775 (+)NCBICelera
Cytogenetic Map19q12NCBI
Necab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955564258,222 - 277,889 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955564257,781 - 279,937 (-)NCBIChiLan1.0ChiLan1.0
NECAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11683,979,108 - 84,013,436 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1683,983,626 - 84,013,436 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01664,636,198 - 64,670,019 (+)NCBIMhudiblu_PPA_v0panPan3
Necab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934928,025,477 - 28,046,190 (-)NCBI
SpeTri2.0NW_0049366413,779,024 - 3,802,883 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.164,598,752 - 4,641,450 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NECAB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1569,380,328 - 69,413,985 (+)NCBI
Necab2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,552,719 - 3,574,124 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 19 6 1 6 8 8 5
Low 5 4 3 5 6 6 4 5 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022419117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022419118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000031781   ⟹   ENSCAFP00000029590
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl568,314,000 - 68,351,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000031783   ⟹   ENSCAFP00000029592
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl568,343,783 - 68,378,311 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000048868   ⟹   ENSCAFP00000037485
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl568,317,500 - 68,351,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000067251   ⟹   ENSCAFP00000060251
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl568,314,000 - 68,351,586 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000081677   ⟹   ENSCAFP00000054074
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl568,347,641 - 68,351,639 (-)Ensembl
RefSeq Acc Id: XM_022419117   ⟹   XP_022274825
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1568,313,699 - 68,342,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022419118   ⟹   XP_022274826
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1568,313,699 - 68,342,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038476985   ⟹   XP_038332913
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1568,559,839 - 68,589,193 (-)NCBI
RefSeq Acc Id: XM_038476986   ⟹   XP_038332914
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1568,559,839 - 68,584,881 (-)NCBI
RefSeq Acc Id: XM_038476987   ⟹   XP_038332915
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1568,559,839 - 68,589,193 (-)NCBI
RefSeq Acc Id: XM_038476988   ⟹   XP_038332916
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1568,559,839 - 68,581,608 (-)NCBI
RefSeq Acc Id: XM_038525893   ⟹   XP_038381821
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha568,327,774 - 68,357,105 (-)NCBI
RefSeq Acc Id: XM_038525901   ⟹   XP_038381829
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha568,327,774 - 68,352,786 (-)NCBI
RefSeq Acc Id: XM_038525910   ⟹   XP_038381838
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha568,327,774 - 68,357,105 (-)NCBI
RefSeq Acc Id: XM_038525921   ⟹   XP_038381849
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha568,327,774 - 68,349,513 (-)NCBI
RefSeq Acc Id: XM_038538164   ⟹   XP_038394092
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0568,812,005 - 68,841,393 (-)NCBI
RefSeq Acc Id: XM_038538165   ⟹   XP_038394093
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0568,812,005 - 68,837,075 (-)NCBI
RefSeq Acc Id: XM_038538166   ⟹   XP_038394094
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0568,812,005 - 68,841,393 (-)NCBI
RefSeq Acc Id: XM_038538167   ⟹   XP_038394095
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0568,812,005 - 68,833,787 (-)NCBI
RefSeq Acc Id: XM_038602290   ⟹   XP_038458218
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0568,396,250 - 68,425,583 (-)NCBI
RefSeq Acc Id: XM_038602292   ⟹   XP_038458220
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0568,396,250 - 68,421,270 (-)NCBI
RefSeq Acc Id: XM_038602293   ⟹   XP_038458221
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0568,396,250 - 68,425,583 (-)NCBI
RefSeq Acc Id: XM_038602294   ⟹   XP_038458222
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0568,396,250 - 68,418,023 (-)NCBI
RefSeq Acc Id: XM_038666905   ⟹   XP_038522833
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0568,612,120 - 68,641,500 (-)NCBI
RefSeq Acc Id: XM_038666906   ⟹   XP_038522834
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0568,612,120 - 68,637,178 (-)NCBI
RefSeq Acc Id: XM_038666907   ⟹   XP_038522835
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0568,612,120 - 68,641,500 (-)NCBI
RefSeq Acc Id: XM_038666908   ⟹   XP_038522836
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0568,612,120 - 68,633,898 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_022274826   ⟸   XM_022419118
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022274825   ⟸   XM_022419117
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000037485   ⟸   ENSCAFT00000048868
RefSeq Acc Id: ENSCAFP00000060251   ⟸   ENSCAFT00000067251
RefSeq Acc Id: ENSCAFP00000029592   ⟸   ENSCAFT00000031783
RefSeq Acc Id: ENSCAFP00000029590   ⟸   ENSCAFT00000031781
RefSeq Acc Id: ENSCAFP00000054074   ⟸   ENSCAFT00000081677
RefSeq Acc Id: XP_038332915   ⟸   XM_038476987
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038332913   ⟸   XM_038476985
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038332914   ⟸   XM_038476986
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038332916   ⟸   XM_038476988
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038458221   ⟸   XM_038602293
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038458218   ⟸   XM_038602290
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458220   ⟸   XM_038602292
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458222   ⟸   XM_038602294
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038522835   ⟸   XM_038666907
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038522833   ⟸   XM_038666905
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038522834   ⟸   XM_038666906
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038522836   ⟸   XM_038666908
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038381838   ⟸   XM_038525910
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038381821   ⟸   XM_038525893
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038381829   ⟸   XM_038525901
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038381849   ⟸   XM_038525921
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038394094   ⟸   XM_038538166
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038394092   ⟸   XM_038538164
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038394093   ⟸   XM_038538165
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038394095   ⟸   XM_038538167
- Peptide Label: isoform X4
Protein Domains
ABM   EF-hand   Pyr_redox_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019970 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000029590 UniProtKB/TrEMBL
  ENSCAFP00000029592 UniProtKB/TrEMBL
  ENSCAFP00000037485 UniProtKB/TrEMBL
  ENSCAFP00000054074 UniProtKB/TrEMBL
  ENSCAFP00000060251 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031781 UniProtKB/TrEMBL
  ENSCAFT00000031783 UniProtKB/TrEMBL
  ENSCAFT00000048868 UniProtKB/TrEMBL
  ENSCAFT00000067251 UniProtKB/TrEMBL
  ENSCAFT00000081677 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
InterPro ABM_dom UniProtKB/TrEMBL
  Dimeric_a/b-barrel UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  FAD/NAD-binding_dom UniProtKB/TrEMBL
  NECAB1/2/3 UniProtKB/TrEMBL
  OKL38_fam UniProtKB/TrEMBL
  OSGIN1 UniProtKB/TrEMBL
NCBI Gene NECAB2 ENTREZGENE
PANTHER PTHR12178 UniProtKB/TrEMBL
  PTHR15192 UniProtKB/TrEMBL
  PTHR15192:SF15 UniProtKB/TrEMBL
Pfam ABM UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/TrEMBL
  Pyr_redox_2 UniProtKB/TrEMBL
PROSITE ABM UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF51905 UniProtKB/TrEMBL
  SSF54909 UniProtKB/TrEMBL
UniProt A0A5F4CMP9_CANLF UniProtKB/TrEMBL
  A0A5F4D0N8_CANLF UniProtKB/TrEMBL
  F1PE40_CANLF UniProtKB/TrEMBL
  F1PER2_CANLF UniProtKB/TrEMBL
  J9NWE0_CANLF UniProtKB/TrEMBL