TXNDC2 (thioredoxin domain containing 2)

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Gene: TXNDC2 (thioredoxin domain containing 2) Canis lupus familiaris

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Symbol:

TXNDC2

Name:

thioredoxin domain containing 2

RGD ID:

12415884

Description:

ENCODES a protein that exhibits protein disulfide isomerase activity (ortholog); thioredoxin-disulfide reductase (NADPH) activity (ortholog); INVOLVED IN cellular response to reactive oxygen species (ortholog); flagellated sperm motility (ortholog); ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); dystonia (ortholog); intellectual disability (ortholog); FOUND IN outer dense fiber (ortholog); sperm flagellum (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

thioredoxin domain-containing 2 (spermatozoa); thioredoxin domain-containing protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	75,822,005 - 75,824,032 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	75,822,013 - 75,824,007 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	75,219,566 - 75,221,603 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	75,879,581 - 75,884,366 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	7	75,580,645 - 75,582,689 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	75,598,431 - 75,600,468 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	75,907,762 - 75,909,799 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

dystonia (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to reactive oxygen species (ISO)

flagellated sperm motility (ISO)

Cellular Component

cytoplasm (IEA)

outer dense fiber (ISO)

sperm flagellum (ISO)

Molecular Function

protein binding (ISO)

protein disulfide isomerase activity (ISO)

thioredoxin-disulfide reductase (NADPH) activity (ISO)

References

Genomics

Comparative Map Data

TXNDC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	75,822,005 - 75,824,032 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	75,822,013 - 75,824,007 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	75,219,566 - 75,221,603 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	75,879,581 - 75,884,366 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	7	75,580,645 - 75,582,689 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	75,598,431 - 75,600,468 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	75,907,762 - 75,909,799 (+)	NCBI		UU_Cfam_GSD_1.0

TXNDC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	9,885,973 - 9,889,275 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	9,885,766 - 9,889,275 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	9,885,970 - 9,889,272 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	9,875,362 - 9,878,156 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	9,875,801 - 9,878,155	NCBI
Celera	18	9,769,333 - 9,771,721 (+)	NCBI		Celera
Cytogenetic Map	18	p11.22	NCBI
HuRef	18	9,847,996 - 9,850,429 (+)	NCBI		HuRef
CHM1_1	18	9,884,991 - 9,887,424 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	10,049,441 - 10,052,739 (+)	NCBI		T2T-CHM13v2.0

Txndc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	65,944,498 - 65,955,871 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	65,944,502 - 65,949,163 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	65,637,505 - 65,648,874 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	65,637,507 - 65,642,168 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	65,986,845 - 65,991,544 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	65,537,057 - 65,539,299 (-)	NCBI		MGSCv36	mm8
Celera	17	69,940,903 - 69,945,602 (-)	NCBI		Celera
Cytogenetic Map	17	E1.1	NCBI
cM Map	17	34.99	NCBI

Txndc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	112,677,459 - 112,682,027 (-)	NCBI		GRCr8
mRatBN7.2	9	105,230,575 - 105,235,131 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	105,230,578 - 105,235,126 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	113,640,107 - 113,644,712 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	118,751,364 - 118,755,868 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	117,106,057 - 117,110,666 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	113,354,047 - 113,358,558 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	113,354,053 - 113,358,526 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	112,886,277 - 112,890,798 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	104,391,636 - 104,396,147 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	104,601,119 - 104,605,609 (-)	NCBI
Celera	9	102,617,140 - 102,621,651 (-)	NCBI		Celera
Cytogenetic Map	9	q37	NCBI

Txndc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955402	2,339,130 - 2,341,283 (-)	NCBI	ChiLan1.0	ChiLan1.0

TXNDC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	28,560,175 - 28,565,275 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	14,252,770 - 14,257,870 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	4,397,565 - 4,401,236 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	6,681,552 - 6,683,778 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Txndc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	2,380,217 - 2,382,276 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936626	1,608,877 - 1,610,472 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TXNDC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	98,271,124 - 98,276,039 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TXNDC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	68,757,934 - 68,760,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	68,758,946 - 68,760,537 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	43,713,693 - 43,715,448 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Txndc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624770	18,383,444 - 18,385,340 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in TXNDC2
39 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	31	20	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005623084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022421634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022421635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482412	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038482413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038543870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038607981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038672672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005430389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000029729 ⟹ ENSCAFP00000027629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	7	75,822,013 - 75,824,007 (+)	Ensembl

RefSeq Acc Id:

XM_005623084 ⟹ XP_005623141

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	75,822,030 - 75,824,032 (+)	NCBI
Dog10K_Boxer_Tasha	7	75,219,568 - 75,221,603 (+)	NCBI

Sequence:

show sequence

TGTACACCAGGCACTGGCCACAGGCCAACACGCAGCAAGACCATCGTTGGAGAGGTTGGAAAAA
GTTGGAGGGTATGACCTCGTCTTCACTATGAGACACTCATGAAGTATAAGCAGATATGGACAAG
GAAATGGAGGTGGAGAATGATAGAGCTGGAGCCCCAGAAGAACCAAAAATGAGGCCAGAGAAAC
AAGAAAAAGCCAATCAAGAAAGTCCATTGTTACAGGGTCTGACCAGCCACGTGACTCCCTTGGT
CCCAGAATTCTTGAACCCAGCACGTATCCAGGAGAAGGCCTTGGCTCATCAGGTCAACAGCATA
CAGCACAAGTCTGCAAAGGAGTCCAAAGGTCCGCAGCCCAAGGACATATTCCTACCTGTATGGG
GTGGTAACAGCTTCAATTTCTCAGCAAAAACCTTGCAGCCTGAACAGGCTGTCATCCCCAATTT
TTCAGCAAAAATCATCTCACCTAACCAGGCTGATACCCCTAATTCTTCAGAAAAAAATATCCCA
CTCAAGCAGGCTGACATCTCTGATTTCTCAGCAAAACCCATCTCACCCAAAGAGGGTAACACCC
CCAGTTTTTTAGCAAAAATCATCCCCCCCAAGCAGTCTGATACCTTCAATTTCCCAGCAAAAAC
CATCCCATCCAATCAGCCTGACACCCCCAATTTTTCAGCAAAAACCATCCCCCCCAAGCAGGCT
GACACCTCCTATTCTTCAGAAAAAATTATCCCACCCAAGGAAGGTGAAATCCCCAATTCCTCGG
AAAAAAACATCCTGAGAAAGGATGACACTACATCTACTTCTTCAGAAAAAAACATCCTGCGCAA
GCAGAGTGACACCACCAAATCACCAGCAAAATCCATCCTGCCTAAACAGGGCAGTAGCCCTAAG
TTCTTAGCAAAATCCATCCTGCCCAAACAGGCCAACACCCCCAAGTTGCCAGCAAAAACTCTCC
AGTCTAAGCAGATCAATAGCCCCAAGGTTTTAGCAAAAAGCATCCTGCCCAAGCACGGCCAAAC
CTCCAAGTCCTCAGAAGAAAACATACTGCCCAGAGAGGGTGACATCAAGTCCTCAGAAGATACC
ATTCAGCCCAAGGAGGGTGACATCCCCAAGTCCTCAAAAGAAATCATCCAGCCTGTAGAAGGCA
ATGTCCTGAAGCCATCAGGGACAATGGAACTCCTGGAGGTGGACTTGGTGAAAGTGATCCTGAA
CAAGGAGGACTTTGAGTTGGCGCTCAAGGAGGCCGGGGAGAGGCTGGTGGCCGTGGACTTCTCG
GCCACCTGGTGTGGGCCTTGCAGGACCATCAAGCCCCTTTTCCGTTCCCTATCCTTAAAGTATG
AGGATGTAGTGTTCCTGGAAGTGGATGCTGATGAGTGTGAGGAGCTGGTGAAAGACCTGGAGAT
CATTTGTATCCCAACCTTTCAGTTTTATAAACAAGAAGAAAAGGTGGGAGAATTTTGTGGCGCT
GTTAAAGAAAAACTTGAGGCAATCATTGCAGAATTAAAGTAATTGTGGCTCCTGAAAGCACCGT
AAA

hide sequence

RefSeq Acc Id:

XM_022421634 ⟹ XP_022277342

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	75,822,018 - 75,824,032 (+)	NCBI
Dog10K_Boxer_Tasha	7	75,219,566 - 75,221,603 (+)	NCBI

Sequence:

show sequence

AATGCCTGTGAATGTACACCAGGCACTGGCCACAGGCCAACACGCAGCAAGACCATCGTAAGTA
ACCAAGGCTGTCATAAAACTCTCAAATACTACTGCTGTGAGTACCAAGAGGGTAAACCAGCTGT
AAGTACTACCCAACTGTAAGTTGTTACTCATTTTATGATGTTAGGTTGGAGAGGTTGGAAAAAG
TTGGAGGGTATGACCTCGTCTTCACTATGAGACACTCATGAAGTATAAGCAGATATGGACAAGG
AAATGGAGGTGGAGAATGATAGAGCTGGAGCCCCAGAAGAACCAAAAATGAGGCCAGAGAAACA
AGAAAAAGCCAATCAAGAAAGTCCATTGTTACAGGGTCTGACCAGCCACGTGACTCCCTTGGTC
CCAGAATTCTTGAACCCAGCACGTATCCAGGAGAAGGCCTTGGCTCATCAGGTCAACAGCATAC
AGCACAAGTCTGCAAAGGAGTCCAAAGGTCCGCAGCCCAAGGACATATTCCTACCTGTATGGGG
TGGTAACAGCTTCAATTTCTCAGCAAAAACCTTGCAGCCTGAACAGGCTGTCATCCCCAATTTT
TCAGCAAAAATCATCTCACCTAACCAGGCTGATACCCCTAATTCTTCAGAAAAAAATATCCCAC
TCAAGCAGGCTGACATCTCTGATTTCTCAGCAAAACCCATCTCACCCAAAGAGGGTAACACCCC
CAGTTTTTTAGCAAAAATCATCCCCCCCAAGCAGTCTGATACCTTCAATTTCCCAGCAAAAACC
ATCCCATCCAATCAGCCTGACACCCCCAATTTTTCAGCAAAAACCATCCCCCCCAAGCAGGCTG
ACACCTCCTATTCTTCAGAAAAAATTATCCCACCCAAGGAAGGTGAAATCCCCAATTCCTCGGA
AAAAAACATCCTGAGAAAGGATGACACTACATCTACTTCTTCAGAAAAAAACATCCTGCGCAAG
CAGAGTGACACCACCAAATCACCAGCAAAATCCATCCTGCCTAAACAGGGCAGTAGCCCTAAGT
TCTTAGCAAAATCCATCCTGCCCAAACAGGCCAACACCCCCAAGTTGCCAGCAAAAACTCTCCA
GTCTAAGCAGATCAATAGCCCCAAGGTTTTAGCAAAAAGCATCCTGCCCAAGCACGGCCAAACC
TCCAAGTCCTCAGAAGAAAACATACTGCCCAGAGAGGGTGACATCAAGTCCTCAGAAGATACCA
TTCAGCCCAAGGAGGGTGACATCCCCAAGTCCTCAAAAGAAATCATCCAGCCTGTAGAAGGCAA
TGTCCTGAAGCCATCAGGGACAATGGAACTCCTGGAGGTGGACTTGGTGAAAGTGATCCTGAAC
AAGGAGGACTTTGAGTTGGCGCTCAAGGAGGCCGGGGAGAGGCTGGTGGCCGTGGACTTCTCGG
CCACCTGGTGTGGGCCTTGCAGGACCATCAAGCCCCTTTTCCGTTCCCTATCCTTAAAGTATGA
GGATGTAGTGTTCCTGGAAGTGGATGCTGATGAGTGTGAGGAGCTGGTGAAAGACCTGGAGATC
ATTTGTATCCCAACCTTTCAGTTTTATAAACAAGAAGAAAAGGTGGGAGAATTTTGTGGCGCTG
TTAAAGAAAAACTTGAGGCAATCATTGCAGAATTAAAGTAATTGTGGCTCCTGAAAGCACCGTA
AA

hide sequence

RefSeq Acc Id:

XM_022421635 ⟹ XP_022277343

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	7	75,822,005 - 75,824,032 (+)	NCBI
Dog10K_Boxer_Tasha	7	75,219,578 - 75,221,603 (+)	NCBI

Sequence:

show sequence

TGTTATAGGAAATAATGCCTGTGAATGTACACCAGGCACTGGCCACAGGCCAACACGCAGCAAG
ACCATCAAAGTCCATTGTTACAGGGTCTGACCAGCCACGTGACTCCCTTGGTCCCAGAATTCTT
GAACCCAGCACGTATCCAGGAGAAGGCCTTGGCTCATCAGGTCAACAGCATACAGCACAAGTCT
GCAAAGGAGTCCAAAGGTCCGCAGCCCAAGGACATATTCCTACCTGTATGGGGTGGTAACAGCT
TCAATTTCTCAGCAAAAACCTTGCAGCCTGAACAGGCTGTCATCCCCAATTTTTCAGCAAAAAT
CATCTCACCTAACCAGGCTGATACCCCTAATTCTTCAGAAAAAAATATCCCACTCAAGCAGGCT
GACATCTCTGATTTCTCAGCAAAACCCATCTCACCCAAAGAGGGTAACACCCCCAGTTTTTTAG
CAAAAATCATCCCCCCCAAGCAGTCTGATACCTTCAATTTCCCAGCAAAAACCATCCCATCCAA
TCAGCCTGACACCCCCAATTTTTCAGCAAAAACCATCCCCCCCAAGCAGGCTGACACCTCCTAT
TCTTCAGAAAAAATTATCCCACCCAAGGAAGGTGAAATCCCCAATTCCTCGGAAAAAAACATCC
TGAGAAAGGATGACACTACATCTACTTCTTCAGAAAAAAACATCCTGCGCAAGCAGAGTGACAC
CACCAAATCACCAGCAAAATCCATCCTGCCTAAACAGGGCAGTAGCCCTAAGTTCTTAGCAAAA
TCCATCCTGCCCAAACAGGCCAACACCCCCAAGTTGCCAGCAAAAACTCTCCAGTCTAAGCAGA
TCAATAGCCCCAAGGTTTTAGCAAAAAGCATCCTGCCCAAGCACGGCCAAACCTCCAAGTCCTC
AGAAGAAAACATACTGCCCAGAGAGGGTGACATCAAGTCCTCAGAAGATACCATTCAGCCCAAG
GAGGGTGACATCCCCAAGTCCTCAAAAGAAATCATCCAGCCTGTAGAAGGCAATGTCCTGAAGC
CATCAGGGACAATGGAACTCCTGGAGGTGGACTTGGTGAAAGTGATCCTGAACAAGGAGGACTT
TGAGTTGGCGCTCAAGGAGGCCGGGGAGAGGCTGGTGGCCGTGGACTTCTCGGCCACCTGGTGT
GGGCCTTGCAGGACCATCAAGCCCCTTTTCCGTTCCCTATCCTTAAAGTATGAGGATGTAGTGT
TCCTGGAAGTGGATGCTGATGAGTGTGAGGAGCTGGTGAAAGACCTGGAGATCATTTGTATCCC
AACCTTTCAGTTTTATAAACAAGAAGAAAAGGTGGGAGAATTTTGTGGCGCTGTTAAAGAAAAA
CTTGAGGCAATCATTGCAGAATTAAAGTAATTGTGGCTCCTGAAAGCACCGTAAA

hide sequence

RefSeq Acc Id:

XM_038482411 ⟹ XP_038338339

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	75,580,645 - 75,582,689 (+)	NCBI

RefSeq Acc Id:

XM_038482412 ⟹ XP_038338340

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	75,580,647 - 75,582,689 (+)	NCBI

RefSeq Acc Id:

XM_038482413 ⟹ XP_038338341

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	7	75,580,657 - 75,582,689 (+)	NCBI

RefSeq Acc Id:

XM_038543868 ⟹ XP_038399796

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	75,907,762 - 75,909,799 (+)	NCBI

RefSeq Acc Id:

XM_038543869 ⟹ XP_038399797

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	75,907,764 - 75,909,799 (+)	NCBI

RefSeq Acc Id:

XM_038543870 ⟹ XP_038399798

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	7	75,907,774 - 75,909,799 (+)	NCBI

RefSeq Acc Id:

XM_038607979 ⟹ XP_038463907

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	75,598,431 - 75,600,468 (+)	NCBI

RefSeq Acc Id:

XM_038607980 ⟹ XP_038463908

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	75,598,433 - 75,600,468 (+)	NCBI

RefSeq Acc Id:

XM_038607981 ⟹ XP_038463909

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	7	75,598,443 - 75,600,468 (+)	NCBI

RefSeq Acc Id:

XM_038672671 ⟹ XP_038528599

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	75,882,332 - 75,884,366 (+)	NCBI

RefSeq Acc Id:

XM_038672672 ⟹ XP_038528600

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	75,882,342 - 75,884,366 (+)	NCBI

RefSeq Acc Id:

XR_005430389

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	7	75,879,581 - 75,883,176 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005623141	(Get FASTA)	NCBI Sequence Viewer
	XP_022277342	(Get FASTA)	NCBI Sequence Viewer
	XP_022277343	(Get FASTA)	NCBI Sequence Viewer
	XP_038338339	(Get FASTA)	NCBI Sequence Viewer
	XP_038338340	(Get FASTA)	NCBI Sequence Viewer
	XP_038338341	(Get FASTA)	NCBI Sequence Viewer
	XP_038399796	(Get FASTA)	NCBI Sequence Viewer
	XP_038399797	(Get FASTA)	NCBI Sequence Viewer
	XP_038399798	(Get FASTA)	NCBI Sequence Viewer
	XP_038463907	(Get FASTA)	NCBI Sequence Viewer
	XP_038463908	(Get FASTA)	NCBI Sequence Viewer
	XP_038463909	(Get FASTA)	NCBI Sequence Viewer
	XP_038528599	(Get FASTA)	NCBI Sequence Viewer
	XP_038528600	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000027629.4
	ENSCAFP00030008670.1
	ENSCAFP00040010491.1
	ENSCAFP00845006578
	ENSCAFP00845006578.1

RefSeq Acc Id:	XP_005623141 ⟸ XM_005623084
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QD83 (UniProtKB/TrEMBL), A0A8P0SMQ7 (UniProtKB/TrEMBL), A0A8C0LIG2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKEMEVENDRAGAPEEPKMRPEKQEKANQESPLLQGLTSHVTPLVPEFLNPARIQEKALAHQV NSIQHKSAKESKGPQPKDIFLPVWGGNSFNFSAKTLQPEQAVIPNFSAKIISPNQADTPNSSEK NIPLKQADISDFSAKPISPKEGNTPSFLAKIIPPKQSDTFNFPAKTIPSNQPDTPNFSAKTIPP KQADTSYSSEKIIPPKEGEIPNSSEKNILRKDDTTSTSSEKNILRKQSDTTKSPAKSILPKQGS SPKFLAKSILPKQANTPKLPAKTLQSKQINSPKVLAKSILPKHGQTSKSSEENILPREGDIKSS EDTIQPKEGDIPKSSKEIIQPVEGNVLKPSGTMELLEVDLVKVILNKEDFELALKEAGERLVAV DFSATWCGPCRTIKPLFRSLSLKYEDVVFLEVDADECEELVKDLEIICIPTFQFYKQEEKVGEF CGAVKEKLEAIIAELK hide sequence

RefSeq Acc Id:	XP_022277343 ⟸ XM_022421635
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LIG2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYTRHWPQANTQQDHQSPLLQGLTSHVTPLVPEFLNPARIQEKALAHQVNSIQHKSAKESKGPQ PKDIFLPVWGGNSFNFSAKTLQPEQAVIPNFSAKIISPNQADTPNSSEKNIPLKQADISDFSAK PISPKEGNTPSFLAKIIPPKQSDTFNFPAKTIPSNQPDTPNFSAKTIPPKQADTSYSSEKIIPP KEGEIPNSSEKNILRKDDTTSTSSEKNILRKQSDTTKSPAKSILPKQGSSPKFLAKSILPKQAN TPKLPAKTLQSKQINSPKVLAKSILPKHGQTSKSSEENILPREGDIKSSEDTIQPKEGDIPKSS KEIIQPVEGNVLKPSGTMELLEVDLVKVILNKEDFELALKEAGERLVAVDFSATWCGPCRTIKP LFRSLSLKYEDVVFLEVDADECEELVKDLEIICIPTFQFYKQEEKVGEFCGAVKEKLEAIIAEL K hide sequence

RefSeq Acc Id:	XP_022277342 ⟸ XM_022421634
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QD83 (UniProtKB/TrEMBL), A0A8P0SMQ7 (UniProtKB/TrEMBL), A0A8C0LIG2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKEMEVENDRAGAPEEPKMRPEKQEKANQESPLLQGLTSHVTPLVPEFLNPARIQEKALAHQV NSIQHKSAKESKGPQPKDIFLPVWGGNSFNFSAKTLQPEQAVIPNFSAKIISPNQADTPNSSEK NIPLKQADISDFSAKPISPKEGNTPSFLAKIIPPKQSDTFNFPAKTIPSNQPDTPNFSAKTIPP KQADTSYSSEKIIPPKEGEIPNSSEKNILRKDDTTSTSSEKNILRKQSDTTKSPAKSILPKQGS SPKFLAKSILPKQANTPKLPAKTLQSKQINSPKVLAKSILPKHGQTSKSSEENILPREGDIKSS EDTIQPKEGDIPKSSKEIIQPVEGNVLKPSGTMELLEVDLVKVILNKEDFELALKEAGERLVAV DFSATWCGPCRTIKPLFRSLSLKYEDVVFLEVDADECEELVKDLEIICIPTFQFYKQEEKVGEF CGAVKEKLEAIIAELK hide sequence

Ensembl Acc Id:

ENSCAFP00000027629 ⟸ ENSCAFT00000029729

RefSeq Acc Id:	XP_038338339 ⟸ XM_038482411
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038338340 ⟸ XM_038482412
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038338341 ⟸ XM_038482413
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038463907 ⟸ XM_038607979
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038463908 ⟸ XM_038607980
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038463909 ⟸ XM_038607981
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038528599 ⟸ XM_038672671
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3MX98 (UniProtKB/TrEMBL), A0A8C0LIG2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038528600 ⟸ XM_038672672
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LIG2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399796 ⟸ XM_038543868
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LIG2 (UniProtKB/TrEMBL), A0A8C0QD83 (UniProtKB/TrEMBL), A0A8P0SMQ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399797 ⟸ XM_038543869
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LIG2 (UniProtKB/TrEMBL), A0A8C0QD83 (UniProtKB/TrEMBL), A0A8P0SMQ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038399798 ⟸ XM_038543870
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LIG2 (UniProtKB/TrEMBL)

Protein Domains

Thioredoxin

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018730	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030005413	UniProtKB/TrEMBL
	ENSCAFG00040006508	UniProtKB/TrEMBL
	ENSCAFG00845004677	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000029729.5	UniProtKB/TrEMBL
	ENSCAFT00030009902.1	UniProtKB/TrEMBL
	ENSCAFT00040012105.1	UniProtKB/TrEMBL
	ENSCAFT00845008359	ENTREZGENE
	ENSCAFT00845008359.1	UniProtKB/TrEMBL
Gene3D-CATH	Glutaredoxin	UniProtKB/TrEMBL
InterPro	Thioredoxin-like_sf	UniProtKB/TrEMBL
	Thioredoxin_domain	UniProtKB/TrEMBL
KEGG Report	cfa:490552	UniProtKB/TrEMBL
NCBI Gene	TXNDC2	ENTREZGENE
PANTHER	THIOREDOXIN	UniProtKB/TrEMBL
	THIOREDOXIN-LIKE PROTEIN 1	UniProtKB/TrEMBL
Pfam	Thioredoxin	UniProtKB/TrEMBL
PROSITE	THIOREDOXIN_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52833	UniProtKB/TrEMBL
UniProt	A0A8C0LIG2	ENTREZGENE
	A0A8C0QD83	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RD78_CANLF	UniProtKB/TrEMBL
	A0A8I3MX98	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SMQ7	ENTREZGENE
UniProt Secondary	A0A8P0SMQ7	UniProtKB/TrEMBL
VGNC ID	VGNC:48014	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar