MIR302A (microRNA mir-302a) - Rat Genome Database

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Gene: MIR302A (microRNA mir-302a) Canis lupus familiaris
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Symbol: MIR302A
Name: microRNA mir-302a
RGD ID: 12415262
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-302a; microRNA 302a
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,429,209 - 32,429,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,429,209 - 32,429,277 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,602,472 - 9,602,540 (+)NCBI
ROS_Cfam_1.03232,655,014 - 32,655,082 (-)NCBI
UMICH_Zoey_3.13232,637,694 - 32,637,762 (-)NCBI
UNSW_CanFamBas_1.03232,399,626 - 32,399,694 (-)NCBI
UU_Cfam_GSD_1.0327,460,915 - 7,460,983 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
aniridia  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18215311  


Genomics

Comparative Map Data
MIR302A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,429,209 - 32,429,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,429,209 - 32,429,277 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,602,472 - 9,602,540 (+)NCBI
ROS_Cfam_1.03232,655,014 - 32,655,082 (-)NCBI
UMICH_Zoey_3.13232,637,694 - 32,637,762 (-)NCBI
UNSW_CanFamBas_1.03232,399,626 - 32,399,694 (-)NCBI
UU_Cfam_GSD_1.0327,460,915 - 7,460,983 (+)NCBI
MIR302A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384112,648,183 - 112,648,251 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4112,648,183 - 112,648,251 (-)EnsemblGRCh38hg38GRCh38
GRCh374113,569,339 - 113,569,407 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364113,788,787 - 113,788,855 (-)NCBINCBI36hg18NCBI36
Celera4110,863,432 - 110,863,500 (-)NCBI
Cytogenetic Map4q25NCBI
HuRef4109,297,759 - 109,297,827 (-)NCBIHuRef
CHM1_14113,545,831 - 113,545,899 (-)NCBICHM1_1
T2T-CHM13v2.04115,956,523 - 115,956,591 (-)NCBI
Mir302a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393127,339,145 - 127,339,213 (+)NCBIGRCm39mm39
GRCm39 Ensembl3127,339,145 - 127,339,213 (+)Ensembl
GRCm383127,545,496 - 127,545,564 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3127,545,496 - 127,545,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv373127,248,414 - 127,248,482 (+)NCBIGRCm37mm9NCBIm37
Celera3134,035,048 - 134,035,116 (+)NCBICelera
Cytogenetic Map3G2NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system nervous system respiratory system
High
Medium
Low 1 5 5 3
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000039947
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3232,429,209 - 32,429,277 (-)Ensembl
RefSeq Acc Id: NR_049443
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13232,429,209 - 32,429,277 (-)NCBI
Dog10K_Boxer_Tasha329,602,472 - 9,602,540 (+)NCBI
ROS_Cfam_1.03232,655,014 - 32,655,082 (-)NCBI
UMICH_Zoey_3.13232,637,694 - 32,637,762 (-)NCBI
UNSW_CanFamBas_1.03232,399,626 - 32,399,694 (-)NCBI
UU_Cfam_GSD_1.0327,460,915 - 7,460,983 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000025664 Ensembl
  ENSCAFG00845017323 ENTREZGENE
Ensembl Transcript ENSCAFT00845030670 ENTREZGENE
miRBase MI0010350 ENTREZGENE
NCBI Gene MIR302A ENTREZGENE
RNAcentral URS0000696DEE RNACentral
  URS000075C59E RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR302A  microRNA mir-302a    microRNA 302a  Symbol and/or name change 5135510 APPROVED