PRDX5 (peroxiredoxin 5) - Rat Genome Database

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Gene: PRDX5 (peroxiredoxin 5) Canis lupus familiaris
Analyze
Symbol: PRDX5
Name: peroxiredoxin 5
RGD ID: 12414034
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process (ortholog); identical protein binding (ortholog); peroxynitrite reductase activity (ortholog); INVOLVED IN cellular response to reactive oxygen species (ortholog); hydrogen peroxide catabolic process (ortholog); NADPH oxidation (ortholog); ASSOCIATED WITH alopecia areata (ortholog); brucellosis (ortholog); Chronic Hepatitis C (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxiredoxin-5, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,750,977 - 52,754,432 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1851,358,049 - 51,361,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,796,390 - 53,800,034 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11852,888,242 - 52,891,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01852,474,829 - 52,478,470 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01853,258,704 - 53,262,348 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:20937353  


Genomics

Comparative Map Data
PRDX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,750,977 - 52,754,432 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1851,358,049 - 51,361,693 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,796,390 - 53,800,034 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11852,888,242 - 52,891,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01852,474,829 - 52,478,470 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01853,258,704 - 53,262,348 (-)NCBIUU_Cfam_GSD_1.0
PRDX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,318,121 - 64,321,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1164,318,121 - 64,321,811 (+)EnsemblGRCh38hg38GRCh38
GRCh371164,085,593 - 64,089,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,842,145 - 63,845,859 (+)NCBINCBI36Build 36hg18NCBI36
Build 341163,842,144 - 63,845,858NCBI
Celera1161,411,653 - 61,415,367 (+)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1160,413,301 - 60,417,036 (+)NCBIHuRef
CHM1_11163,968,573 - 63,972,308 (+)NCBICHM1_1
T2T-CHM13v2.01164,308,102 - 64,311,792 (+)NCBIT2T-CHM13v2.0
Prdx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,884,065 - 6,887,474 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,884,065 - 6,887,474 (-)EnsemblGRCm39 Ensembl
GRCm38196,906,697 - 6,910,106 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,906,697 - 6,910,106 (-)EnsemblGRCm38mm10GRCm38
MGSCv37196,981,309 - 6,984,135 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,973,863 - 6,976,689 (-)NCBIMGSCv36mm8
Celera196,683,601 - 6,686,426 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.08NCBI
Prdx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21204,099,826 - 204,103,589 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1204,099,826 - 204,114,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,450,032 - 212,453,015 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01219,545,095 - 219,548,082 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01212,236,145 - 212,239,134 (-)NCBIRnor_WKY
Rnor_6.01222,164,462 - 222,167,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,164,462 - 222,167,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01229,155,316 - 229,158,301 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,583,414 - 209,586,399 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,741,843 - 209,744,829 (-)NCBI
Celera1201,633,781 - 201,636,766 (-)NCBICelera
Cytogenetic Map1q43NCBI
Prdx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,761,495 - 20,766,976 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,763,822 - 20,766,976 (-)NCBIChiLan1.0ChiLan1.0
PRDX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11163,020,097 - 63,023,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,020,097 - 63,023,624 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01159,675,138 - 59,678,804 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Prdx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049478,452,065 - 8,455,009 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,894,409 - 4,897,223 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365994,894,409 - 4,897,426 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRDX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,798,670 - 7,802,952 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,798,672 - 7,801,955 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,864,489 - 6,867,774 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRDX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,912,947 - 9,917,439 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,912,898 - 9,917,361 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038107,253,189 - 107,257,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prdx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,995,681 - 21,997,149 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,995,542 - 21,998,609 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PRDX5
38 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038425166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038425167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038425168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038564112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038564113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038564114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_533241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_038425166   ⟹   XP_038281094
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01853,796,390 - 53,800,034 (-)NCBI
RefSeq Acc Id: XM_038425167   ⟹   XP_038281095
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01853,796,390 - 53,798,242 (-)NCBI
RefSeq Acc Id: XM_038425168   ⟹   XP_038281096
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01853,796,390 - 53,799,511 (-)NCBI
RefSeq Acc Id: XM_038453801   ⟹   XP_038309729
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1851,358,049 - 51,361,693 (-)NCBI
RefSeq Acc Id: XM_038453803   ⟹   XP_038309731
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1851,358,049 - 51,359,901 (-)NCBI
RefSeq Acc Id: XM_038501427   ⟹   XP_038357355
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11852,888,242 - 52,891,882 (-)NCBI
RefSeq Acc Id: XM_038501428   ⟹   XP_038357356
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11852,888,242 - 52,890,091 (-)NCBI
RefSeq Acc Id: XM_038501429   ⟹   XP_038357357
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11852,888,242 - 52,891,360 (-)NCBI
RefSeq Acc Id: XM_038564112   ⟹   XP_038420040
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01853,258,704 - 53,262,348 (-)NCBI
RefSeq Acc Id: XM_038564113   ⟹   XP_038420041
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01853,258,704 - 53,260,556 (-)NCBI
RefSeq Acc Id: XM_038564114   ⟹   XP_038420042
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01853,258,704 - 53,261,825 (-)NCBI
RefSeq Acc Id: XM_038628265   ⟹   XP_038484193
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01852,474,829 - 52,478,470 (-)NCBI
RefSeq Acc Id: XM_038628266   ⟹   XP_038484194
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01852,474,829 - 52,476,678 (-)NCBI
RefSeq Acc Id: XM_038628267   ⟹   XP_038484195
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01852,474,829 - 52,477,947 (-)NCBI
RefSeq Acc Id: XM_533241   ⟹   XP_533241
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11852,750,977 - 52,754,432 (-)NCBI
Dog10K_Boxer_Tasha1851,358,049 - 51,361,170 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_533241   ⟸   XM_533241
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_038357355   ⟸   XM_038501427
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038357357   ⟸   XM_038501429
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038357356   ⟸   XM_038501428
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038484193   ⟸   XM_038628265
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038484195   ⟸   XM_038628267
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038484194   ⟸   XM_038628266
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038281094   ⟸   XM_038425166
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038281096   ⟸   XM_038425168
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038281095   ⟸   XM_038425167
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038309729   ⟸   XM_038453801
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038309731   ⟸   XM_038453803
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038420040   ⟸   XM_038564112
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038420042   ⟸   XM_038564114
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038420041   ⟸   XM_038564113
- Peptide Label: isoform X2
Protein Domains
Redoxin   Thioredoxin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000045013 UniProtKB/TrEMBL
  ENSCAFG00845030543 UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000021305.4 UniProtKB/TrEMBL
  ENSCAFP00000066439.1 UniProtKB/TrEMBL
  ENSCAFP00000073273.1 UniProtKB/TrEMBL
  ENSCAFP00845042568.1 UniProtKB/TrEMBL
  ENSCAFP00845042577.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000022937.5 UniProtKB/TrEMBL
  ENSCAFT00000091507.2 UniProtKB/TrEMBL
  ENSCAFT00000107188.1 UniProtKB/TrEMBL
  ENSCAFT00845054179.1 UniProtKB/TrEMBL
  ENSCAFT00845054194.1 UniProtKB/TrEMBL
InterPro PRX5-like UniProtKB/TrEMBL
  Redoxin UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
NCBI Gene PRDX5 ENTREZGENE
PANTHER PTHR10430 UniProtKB/TrEMBL
Pfam Redoxin UniProtKB/TrEMBL
PROSITE THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A8I3Q4L7_CANLF UniProtKB/TrEMBL
  A0A8I3QY82_CANLF UniProtKB/TrEMBL
  A0A8P0NG13_CANLF UniProtKB/TrEMBL
  A0A8P0PF16_CANLF UniProtKB/TrEMBL
  A0A8P0TRG3_CANLF UniProtKB/TrEMBL