GAL (galanin and GMAP prepropeptide) - Rat Genome Database

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Advanced Search (OLGA)
Gene: GAL (galanin and GMAP prepropeptide) Canis lupus familiaris
Analyze
Symbol: GAL
Name: galanin and GMAP prepropeptide
RGD ID: 12411562
Description: ENCODES a protein that exhibits galanin receptor activity (ortholog); neuropeptide hormone activity (ortholog); type 1 galanin receptor binding (ortholog); INVOLVED IN feeding behavior (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of lymphocyte proliferation (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); brain ischemia (ortholog); depressive disorder (ortholog); FOUND IN extracellular space (ortholog); neuron projection terminus (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: galanin peptides; galanin prepropeptide; GALN
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,240,437 - 49,246,543 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,240,437 - 49,246,950 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,849,939 - 47,855,743 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,155,635 - 50,161,742 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,155,635 - 50,161,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,376,255 - 49,382,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01848,950,015 - 48,955,820 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01849,743,208 - 49,749,012 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:7512738   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GAL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,240,437 - 49,246,543 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,240,437 - 49,246,950 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1847,849,939 - 47,855,743 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,155,635 - 50,161,742 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,155,635 - 50,161,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,376,255 - 49,382,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01848,950,015 - 48,955,820 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01849,743,208 - 49,749,012 (-)NCBIUU_Cfam_GSD_1.0
GAL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,684,544 - 68,691,175 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,683,779 - 68,691,175 (+)EnsemblGRCh38hg38GRCh38
GRCh371168,452,012 - 68,458,643 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,208,559 - 68,215,219 (+)NCBINCBI36Build 36hg18NCBI36
Build 341168,208,610 - 68,215,219NCBI
Celera1165,788,525 - 65,795,257 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1164,788,371 - 64,795,031 (+)NCBIHuRef
CHM1_11168,335,752 - 68,342,412 (+)NCBICHM1_1
T2T-CHM13v2.01168,690,664 - 68,697,295 (+)NCBIT2T-CHM13v2.0
Gal
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,459,915 - 3,464,544 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,459,915 - 3,464,544 (-)EnsemblGRCm39 Ensembl
GRCm38193,409,915 - 3,414,544 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,409,915 - 3,414,544 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,409,917 - 3,414,457 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,409,917 - 3,414,457 (-)NCBIMGSCv36mm8
Celera193,279,401 - 3,283,920 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.16NCBI
Gal
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,079,709 - 210,084,572 (-)NCBIGRCr8
mRatBN7.21200,650,439 - 200,655,302 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1200,650,439 - 200,654,959 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,023,646 - 209,028,521 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,112,399 - 216,117,262 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01208,786,607 - 208,791,470 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01218,653,059 - 218,657,922 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,652,917 - 218,657,925 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,520,966 - 225,525,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,936,352 - 205,941,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11206,089,804 - 206,094,668 (-)NCBI
Celera1198,205,890 - 198,210,753 (-)NCBICelera
Cytogenetic Map1q42NCBI
Gal
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,202,946 - 17,207,948 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,202,770 - 17,207,948 (-)NCBIChiLan1.0ChiLan1.0
GAL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2969,636,630 - 69,646,600 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11170,679,823 - 70,689,785 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01163,770,758 - 63,777,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11167,075,104 - 67,081,696 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1167,075,547 - 67,081,696 (+)Ensemblpanpan1.1panPan2
Gal
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,120,761 - 5,125,269 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365991,563,270 - 1,566,158 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365991,563,270 - 1,567,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl24,351,113 - 4,356,647 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.124,351,113 - 4,357,167 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.222,931,347 - 2,937,425 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115,849,947 - 5,857,355 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15,849,952 - 5,857,072 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038103,132,895 - 103,140,180 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gal
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476718,204,508 - 18,210,416 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476718,195,288 - 18,210,634 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GAL
99 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
4 5 4 21 20 13 4 5 4 6 25 16 10 14 9

Sequence


Ensembl Acc Id: ENSCAFT00000017134   ⟹   ENSCAFP00000015855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1849,240,437 - 49,246,950 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845012176   ⟹   ENSCAFP00845009517
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1850,155,635 - 50,161,523 (-)Ensembl
RefSeq Acc Id: NM_001313781   ⟹   NP_001300710
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11849,240,437 - 49,246,241 (-)NCBI
Dog10K_Boxer_Tasha1847,849,939 - 47,855,743 (-)NCBI
ROS_Cfam_1.01850,155,635 - 50,161,450 (-)NCBI
UMICH_Zoey_3.11849,376,255 - 49,382,059 (-)NCBI
UNSW_CanFamBas_1.01848,950,015 - 48,955,820 (-)NCBI
UU_Cfam_GSD_1.01849,743,208 - 49,749,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038423389   ⟹   XP_038279317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01850,155,635 - 50,161,742 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001300710 (Get FASTA)   NCBI Sequence Viewer  
  XP_038279317 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA30845 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00845009517
GenBank Protein P33710 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001300710   ⟸   NM_001313781
- Peptide Label: precursor
- UniProtKB: A0A8I3RTK9 (UniProtKB/TrEMBL),   A0A8P0NCR9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000015855   ⟸   ENSCAFT00000017134
RefSeq Acc Id: XP_038279317   ⟸   XM_038423389
- Peptide Label: isoform X1
- UniProtKB: A0A8I3RTK9 (UniProtKB/TrEMBL),   A0A8P0NCR9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845009517   ⟸   ENSCAFT00845012176
Protein Domains
GALANIN

Promoters
RGD ID:13686556
Promoter ID:EPDNEW_C4624
Type:single initiation site
Name:GAL_1
Description:galanin and GMAP prepropeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11849,246,353 - 49,246,413EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010772 Ensembl
  ENSCAFG00845006857 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845012176 ENTREZGENE
InterPro Galanin UniProtKB/Swiss-Prot
  Galanin_pre UniProtKB/Swiss-Prot
NCBI Gene GAL ENTREZGENE
PANTHER GALANIN PEPTIDES UniProtKB/Swiss-Prot
  PTHR16839 UniProtKB/Swiss-Prot
Pfam Galanin UniProtKB/Swiss-Prot
SMART Galanin UniProtKB/Swiss-Prot
UniProt A0A8I3RTK9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NCR9 ENTREZGENE, UniProtKB/TrEMBL
  GALA_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:41075 ENTREZGENE