OR7D2 (olfactory receptor family 7 subfamily D member 2)

Gene: OR7D2 (olfactory receptor family 7 subfamily D member 2) Canis lupus familiaris

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Symbol:

OR7D2

Name:

olfactory receptor family 7 subfamily D member 2

RGD ID:

12409530

Description:

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC611376; olfactory receptor 7D2; OR04C11; OR10B04

RGD Orthologs

Human

Pig

Green Monkey

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	51,472,187 - 51,473,650 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	51,472,505 - 51,473,443 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	51,335,608 - 51,337,086 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	51,993,722 - 51,995,200 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	51,994,056 - 51,994,994 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	51,200,839 - 51,202,317 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	51,625,827 - 51,627,305 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	51,867,703 - 51,869,181 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IEA)

G protein-coupled receptor signaling pathway (IEA)

regulation of DNA-templated transcription (IEA,ISO)

sensory perception of smell (IEA)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

OR7D2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	51,472,187 - 51,473,650 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	51,472,505 - 51,473,443 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	51,335,608 - 51,337,086 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	51,993,722 - 51,995,200 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	51,994,056 - 51,994,994 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	51,200,839 - 51,202,317 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	51,625,827 - 51,627,305 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	51,867,703 - 51,869,181 (-)	NCBI		UU_Cfam_GSD_1.0

OR7D2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	9,178,979 - 9,188,818 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	9,178,979 - 9,188,818 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	9,289,655 - 9,299,494 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	9,157,270 - 9,160,493 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	9,157,269 - 9,160,493	NCBI
Celera	19	9,191,715 - 9,194,938 (+)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	8,877,810 - 8,881,033 (+)	NCBI		HuRef
CHM1_1	19	9,295,931 - 9,299,154 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	9,305,174 - 9,315,012 (+)	NCBI		T2T-CHM13v2.0

LOC100516898
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	67,372,003 - 67,375,663 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	67,372,588 - 67,373,525 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	67,726,388 - 67,727,329 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103233855
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	8,386,269 - 8,409,876 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	8,408,832 - 8,409,770 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	11,742,053 - 11,743,380 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in OR7D2
18 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038428712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038504355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038567388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038631535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_849038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ431421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ431471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000067426 ⟹ ENSCAFP00000054231

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	51,472,505 - 51,473,443 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845042031 ⟹ ENSCAFP00845032967

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	51,994,056 - 51,994,994 (-)	Ensembl

RefSeq Acc Id:

XM_038428712 ⟹ XP_038284640

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	51,993,722 - 51,995,200 (-)	NCBI

RefSeq Acc Id:

XM_038504355 ⟹ XP_038360283

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	20	51,200,839 - 51,202,317 (-)	NCBI

RefSeq Acc Id:

XM_038567388 ⟹ XP_038423316

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	20	51,867,703 - 51,869,181 (-)	NCBI

RefSeq Acc Id:

XM_038631535 ⟹ XP_038487463

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	20	51,625,827 - 51,627,305 (-)	NCBI

RefSeq Acc Id:

XM_849038 ⟹ XP_854131

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	20	51,472,187 - 51,473,650 (-)	NCBI
Dog10K_Boxer_Tasha	20	51,335,608 - 51,337,086 (-)	NCBI

Sequence:

show sequence

CTCTGACTGGCTTATTTTCTTAAGATGGGTGGTTGGCGTAAGACTCCATTTTTTTCTGATCTCA
CTTATAAGACCCAACACTTACTCAAAATGACTGACCTCATAAATAACTTGAGCAAAAGGCCAAC
ATTTTTGTTAAATGGAGGGTGCCACTTTGCTGCTACTTCATGTTACTCTTGTCTCTTCCTTTAT
AGATATATCGGGTACATGGAAGCAGGAAATCTAACAGGAATTTTAGAGTTCATCCTCCTTGGGT
TCTCTGAGGATCCAGAACTACAACCCTTCATATTTGGGCTATTCCTGTGTATGTTCCTGGTCAC
TGTGCTTGGGAACCTGCTCATCATCCTGGCCATCTGCTCTGACCCCCACCTCCATACCCCCATG
TACTTCTTCCTCTCCAATCTGTCGTTGGTTGACATCTGTTTCAGCACCACCATAGTGCCCAAGA
TGCTGGTGAACATCCACACAGAGAACAAAGCCATCTCCTACATGGACTGCCTCACGCAGGTATA
TTTTTCCATGTTTTTTCCCATCCTAGACACTCTACTCCTTACTGTAATGGCCTATGACCGGTTT
GTGGCCATCTGCCACCCCCTGCACTACACAGTCATCATGAGCCCACGCCTCTGTGGCCTGTTGG
TTTTTGCTACCTGGTTTGTTGGTATCATGACATCCCTTCTTCATATCTCTCTGATGAGGCACCT
GAGCTTCTGCAGAGACCTTGAAATTCCACATTTCTTCTGTGAACTGACACAGATTCTCAAGTTG
GCCTGCTCTGATACCTTTCTGAACAGCACGTTGATATACTTTATGACTGGTGTGCTGGGTGTTT
TTCCCCTTGTTGGTATCCTTTTCTCCTACTCACAGATTGCTTCATCTATAAGGAAGATGTCTTC
ATCTGGGGGAAAGCAAAAAGCATTTTCCACCTGTGGGTCTCACCTCTCAGTTGTTTCTTTATTT
TATGGGACAGGTGTTGGGGTATACTTCACTTCTGCAGTAACTCACTCCCCCCAGAAAGTCTCAG
TGGCTTCAGTGATGTACACTGTGGTCACCCCCATGCTGAACCCCTTCATCTACAGCCTGAGGAA
CAAGGATGTGAAGGGGGCACTGGGAAGCCTTCTCAGTAGAGTGACCTCTTGTCTGTGATGGATA
TACTGGCCCTAGGACTAAGGAGTTTTCTGGATCCCAAGGGCAAAACTTTGATTCTAAAGTTTAC
TCTTGAATCTTGCAAACTCTGTTTCACCCAGTCTTGAAGGATCTATGATTACTCTCTCCTAGTT
TTTACACACTTTTAAACAACTAATTTCTGCATAATTTATCTGATGATCTTTCTGCCCTATCTGT
TGTCCAAAAAAGTATGTCCTCAGGATGCCTGGGTGACTCAGAGGTTGAGCACCTGCCTTCGGCT
CAGGGCATGATCCCAGGCCTGGGGATCGAGTCCCACATCGGACTCACTGTGAGGAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_038284640	(Get FASTA)	NCBI Sequence Viewer
	XP_038360283	(Get FASTA)	NCBI Sequence Viewer
	XP_038423316	(Get FASTA)	NCBI Sequence Viewer
	XP_038487463	(Get FASTA)	NCBI Sequence Viewer
	XP_854131	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAD24131	(Get FASTA)	NCBI Sequence Viewer
	CAD24181	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000054231.1
	ENSCAFP00030016456.1
	ENSCAFP00040038602.1
	ENSCAFP00845032967
	ENSCAFP00845032967.1

RefSeq Acc Id:

XP_854131 ⟸ XM_849038

- Sequence:

show sequence

MGGWRKTPFFSDLTYKTQHLLKMTDLINNLSKRPTFLLNGGCHFAATSCYSCLFLYRYIGYMEA
GNLTGILEFILLGFSEDPELQPFIFGLFLCMFLVTVLGNLLIILAICSDPHLHTPMYFFLSNLS
LVDICFSTTIVPKMLVNIHTENKAISYMDCLTQVYFSMFFPILDTLLLTVMAYDRFVAICHPLH
YTVIMSPRLCGLLVFATWFVGIMTSLLHISLMRHLSFCRDLEIPHFFCELTQILKLACSDTFLN
STLIYFMTGVLGVFPLVGILFSYSQIASSIRKMSSSGGKQKAFSTCGSHLSVVSLFYGTGVGVY
FTSAVTHSPQKVSVASVMYTVVTPMLNPFIYSLRNKDVKGALGSLLSRVTSCL

hide sequence

RefSeq Acc Id:

ENSCAFP00000054231 ⟸ ENSCAFT00000067426

RefSeq Acc Id:

XP_038360283 ⟸ XM_038504355

RefSeq Acc Id:

XP_038487463 ⟸ XM_038631535

RefSeq Acc Id:

XP_038284640 ⟸ XM_038428712

RefSeq Acc Id:

XP_038423316 ⟸ XM_038567388

RefSeq Acc Id:

ENSCAFP00845032967 ⟸ ENSCAFT00845042031

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000046909	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030010197	UniProtKB/TrEMBL
	ENSCAFG00040023758	UniProtKB/TrEMBL
	ENSCAFG00845023810	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000067426.2	UniProtKB/TrEMBL
	ENSCAFT00030018856.1	UniProtKB/TrEMBL
	ENSCAFT00040044219.1	UniProtKB/TrEMBL
	ENSCAFT00845042031	ENTREZGENE
	ENSCAFT00845042031.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
KEGG Report	cfa:611376	UniProtKB/TrEMBL
NCBI Gene	LOC611376	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 7D2	UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C0Z5Q4_CANLF	UniProtKB/TrEMBL
	A0A8I3PYA1_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:98564	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-03-04	OR7D2	olfactory receptor family 7 subfamily D member 2	LOC611376	olfactory receptor 7D2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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