FOXI2 (forkhead box I2) - Rat Genome Database

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Gene: FOXI2 (forkhead box I2) Canis lupus familiaris
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Symbol: FOXI2
Name: forkhead box I2
RGD ID: 12406224
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN anatomical structure morphogenesis (inferred); cell differentiation (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH distal 10q deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein I2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,636,733 - 36,638,597 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,636,733 - 36,640,811 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2836,692,416 - 36,694,276 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02837,268,414 - 37,270,274 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2837,268,256 - 37,271,906 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,748,651 - 36,750,507 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,743,259 - 36,745,126 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02836,997,953 - 36,999,813 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FOXI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12836,636,733 - 36,638,597 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2836,636,733 - 36,640,811 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2836,692,416 - 36,694,276 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02837,268,414 - 37,270,274 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2837,268,256 - 37,271,906 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12836,748,651 - 36,750,507 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02836,743,259 - 36,745,126 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02836,997,953 - 36,999,813 (+)NCBIUU_Cfam_GSD_1.0
FOXI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810127,737,185 - 127,741,183 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10127,737,185 - 127,741,183 (+)EnsemblGRCh38hg38GRCh38
GRCh3710129,535,449 - 129,539,447 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610129,425,942 - 129,429,440 (+)NCBINCBI36Build 36hg18NCBI36
Celera10123,207,312 - 123,211,234 (+)NCBICelera
Cytogenetic Map10q26.2NCBI
HuRef10123,109,651 - 123,113,577 (+)NCBIHuRef
CHM1_110129,818,007 - 129,821,915 (+)NCBICHM1_1
T2T-CHM13v2.010128,633,615 - 128,637,627 (+)NCBIT2T-CHM13v2.0
Foxi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397135,012,096 - 135,015,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7135,012,037 - 135,015,351 (+)EnsemblGRCm39 Ensembl
GRCm387135,410,367 - 135,413,622 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7135,410,308 - 135,413,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv377142,602,050 - 142,605,298 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367135,248,710 - 135,251,958 (+)NCBIMGSCv36mm8
Celera7135,232,708 - 135,235,957 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map781.27NCBI
Foxi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81199,652,703 - 199,656,503 (+)NCBIGRCr8
mRatBN7.21190,222,857 - 190,226,657 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1190,222,703 - 190,226,433 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01207,653,704 - 207,656,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1207,654,487 - 207,656,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01214,587,196 - 214,589,653 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41195,036,540 - 195,038,191 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11195,186,897 - 195,187,838 (+)NCBI
Celera1187,937,460 - 187,940,587 (+)NCBICelera
Cytogenetic Map1q41NCBI
Foxi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554775,548,812 - 5,551,313 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554775,548,676 - 5,552,882 (+)NCBIChiLan1.0ChiLan1.0
FOXI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28139,615,597 - 139,617,287 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110139,620,948 - 139,622,638 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010124,325,031 - 124,327,965 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110128,574,023 - 128,576,782 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10128,574,023 - 128,576,782 (+)Ensemblpanpan1.1panPan2
Foxi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721310,239,422 - 10,241,206 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648615,320,044 - 15,321,691 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648615,320,044 - 15,321,691 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14136,986,720 - 136,989,551 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114136,986,882 - 136,988,565 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214148,652,845 - 148,654,517 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FOXI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19120,355,102 - 120,359,663 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9120,355,174 - 120,356,864 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604881,744,913 - 81,746,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473719,269,115 - 19,270,718 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473719,269,071 - 19,270,718 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FOXI2
58 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system nervous system reproductive system respiratory system
High
Medium
Low 2 6 3 3
Below cutoff 1 14 1 1 3 11 5 7

Sequence


RefSeq Acc Id: ENSCAFT00000020834   ⟹   ENSCAFP00000019343
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2836,636,733 - 36,640,811 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845049094   ⟹   ENSCAFP00845038517
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2837,268,256 - 37,271,906 (+)Ensembl
RefSeq Acc Id: XM_038439659   ⟹   XP_038295587
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02837,268,414 - 37,270,274 (+)NCBI
RefSeq Acc Id: XM_038515628   ⟹   XP_038371556
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12836,748,651 - 36,750,507 (+)NCBI
RefSeq Acc Id: XM_038577987   ⟹   XP_038433915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02836,997,953 - 36,999,813 (+)NCBI
RefSeq Acc Id: XM_038642111   ⟹   XP_038498039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02836,743,259 - 36,745,126 (+)NCBI
RefSeq Acc Id: XM_849276   ⟹   XP_854369
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12836,636,733 - 36,638,597 (+)NCBI
Dog10K_Boxer_Tasha2836,692,416 - 36,694,276 (+)NCBI
Sequence:
RefSeq Acc Id: XP_854369   ⟸   XM_849276
- UniProtKB: A0A8P0NF41 (UniProtKB/TrEMBL),   A0A8C0PN58 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000019343   ⟸   ENSCAFT00000020834
RefSeq Acc Id: XP_038371556   ⟸   XM_038515628
RefSeq Acc Id: XP_038498039   ⟸   XM_038642111
RefSeq Acc Id: XP_038295587   ⟸   XM_038439659
- UniProtKB: A0A8I3S6G8 (UniProtKB/TrEMBL),   A0A8C0PN58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433915   ⟸   XM_038577987
- UniProtKB: A0A8C0PN58 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845038517   ⟸   ENSCAFT00845049094
Protein Domains
Fork-head


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013126 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030026293 UniProtKB/TrEMBL
  ENSCAFG00040022804 UniProtKB/TrEMBL
  ENSCAFG00845027825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020834.5 UniProtKB/TrEMBL
  ENSCAFT00030048685.1 UniProtKB/TrEMBL
  ENSCAFT00040042369.1 UniProtKB/TrEMBL
  ENSCAFT00845049094 ENTREZGENE
  ENSCAFT00845049094.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Fork_head_dom UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene FOXI2 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN I2 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0PN58 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S6G8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NF41 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40952 ENTREZGENE