NAXE (NAD(P)HX epimerase) - Rat Genome Database

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Gene: NAXE (NAD(P)HX epimerase) Canis lupus familiaris
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Symbol: NAXE
Name: NAD(P)HX epimerase
RGD ID: 12404640
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN membrane raft distribution (ortholog); negative regulation of angiogenesis (ortholog); nicotinamide nucleotide metabolic process (ortholog); ASSOCIATED WITH brain disease (ortholog); Early-Onset Progressive Encephalopathy with Brain Edema and/or Leukoencephalopathy (ortholog); Early-Onset Progressive Encephalopathy with Brain Edema and/or Leukoencephalopathy 1 (ortholog); FOUND IN cell body (ortholog); cilium (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: AI-BP; AIBP; APOA1BP; Apolipoprotein A-I-binding protein; LOW QUALITY PROTEIN: NAD(P)H-hydrate epimerase; NAD(P)H-hydrate epimerase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,367,248 - 41,369,733 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,367,275 - 41,369,862 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,854,553 - 40,857,041 (-)NCBI
ROS_Cfam_1.0741,230,402 - 41,232,892 (-)NCBI
UMICH_Zoey_3.1741,012,056 - 41,014,536 (-)NCBI
UNSW_CanFamBas_1.0741,065,296 - 41,067,780 (-)NCBI
UU_Cfam_GSD_1.0741,348,969 - 41,351,458 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
NAXE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,367,248 - 41,369,733 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,367,275 - 41,369,862 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,854,553 - 40,857,041 (-)NCBI
ROS_Cfam_1.0741,230,402 - 41,232,892 (-)NCBI
UMICH_Zoey_3.1741,012,056 - 41,014,536 (-)NCBI
UNSW_CanFamBas_1.0741,065,296 - 41,067,780 (-)NCBI
UU_Cfam_GSD_1.0741,348,969 - 41,351,458 (-)NCBI
NAXE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1156,591,756 - 156,609,507 (+)EnsemblGRCh38hg38GRCh38
GRCh381156,591,776 - 156,599,818 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371156,561,568 - 156,564,091 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,828,182 - 154,830,715 (+)NCBINCBI36hg18NCBI36
Build 341153,374,642 - 153,377,162NCBI
Celera1129,632,348 - 129,634,881 (+)NCBI
Cytogenetic Map1q22NCBI
HuRef1127,919,237 - 127,921,770 (+)NCBIHuRef
CHM1_11157,957,748 - 157,960,281 (+)NCBICHM1_1
Naxe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,963,827 - 87,965,851 (-)NCBIGRCm39mm39
GRCm39 Ensembl387,963,827 - 87,965,802 (-)Ensembl
GRCm38388,056,520 - 88,058,542 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,056,520 - 88,058,495 (-)EnsemblGRCm38mm10GRCm38
MGSCv37387,860,445 - 87,862,417 (-)NCBIGRCm37mm9NCBIm37
MGSCv36388,142,450 - 88,144,422 (-)NCBImm8
Celera388,096,041 - 88,098,013 (-)NCBICelera
Cytogenetic Map3F1NCBI
Naxe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22173,518,966 - 173,521,048 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2173,518,971 - 173,521,040 (-)Ensembl
Rnor_6.02187,424,319 - 187,426,410 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,424,327 - 187,426,375 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,827,336 - 206,829,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,132,497 - 180,134,558 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,082,661 - 180,094,499 (-)NCBI
Celera2167,466,212 - 167,468,273 (-)NCBICelera
Cytogenetic Map2q34NCBI
Naxe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,682,385 - 2,684,518 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,682,384 - 2,687,348 (+)NCBIChiLan1.0ChiLan1.0
NAXE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11135,758,868 - 135,761,416 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,758,868 - 135,761,416 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01131,935,295 - 131,937,843 (+)NCBIMhudiblu_PPA_v0panPan3
Naxe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,739,217 - 26,742,251 (+)NCBI
SpeTri2.0NW_0049365805,769,583 - 5,772,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAXE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,490,537 - 93,496,341 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,493,234 - 93,495,912 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,289,153 - 102,291,831 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAXE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,267,885 - 7,270,440 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl207,268,100 - 7,270,442 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660386,564,280 - 6,567,063 (-)NCBIVero_WHO_p1.0
Naxe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,780,894 - 1,783,288 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000026588   ⟹   ENSCAFP00000024694
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl741,367,275 - 41,369,862 (-)Ensembl
RefSeq Acc Id: XM_038481627   ⟹   XP_038337555
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1741,012,056 - 41,014,536 (-)NCBI
RefSeq Acc Id: XM_038543003   ⟹   XP_038398931
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0741,348,969 - 41,351,458 (-)NCBI
RefSeq Acc Id: XM_038607118   ⟹   XP_038463046
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0741,065,296 - 41,067,780 (-)NCBI
RefSeq Acc Id: XM_038671842   ⟹   XP_038527770
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0741,230,402 - 41,232,892 (-)NCBI
RefSeq Acc Id: XM_849841   ⟹   XP_854934
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1741,367,248 - 41,369,733 (-)NCBI
Dog10K_Boxer_Tasha740,854,553 - 40,857,041 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038337555 (Get FASTA)   NCBI Sequence Viewer  
  XP_038398931 (Get FASTA)   NCBI Sequence Viewer  
  XP_038463046 (Get FASTA)   NCBI Sequence Viewer  
  XP_038527770 (Get FASTA)   NCBI Sequence Viewer  
  XP_854934 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein E2QRY6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_854934   ⟸   XM_849841
- Sequence:
RefSeq Acc Id: ENSCAFP00000024694   ⟸   ENSCAFT00000026588
RefSeq Acc Id: XP_038337555   ⟸   XM_038481627
RefSeq Acc Id: XP_038463046   ⟸   XM_038607118
RefSeq Acc Id: XP_038527770   ⟸   XM_038671842
RefSeq Acc Id: XP_038398931   ⟸   XM_038543003


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016794 Ensembl
NCBI Gene NAXE ENTREZGENE
UniProt E2QRY6 ENTREZGENE
VGNC ID VGNC:53623 ENTREZGENE