IL13 (interleukin 13) - Rat Genome Database

Name: IL13
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: IL13 (interleukin 13) Canis lupus familiaris

Analyze

Symbol:

IL13

Name:

interleukin 13

RGD ID:

12404079

Description:

ENCODES a protein that exhibits interleukin-13 receptor binding (ortholog); INVOLVED IN cellular response to cytokine stimulus (ortholog); cellular response to mechanical stimulus (ortholog); inflammatory response (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); alcoholic hepatitis (ortholog); allergic conjunctivitis (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH cannabidiol; luteolin; masitinib

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

IL-13; interleukin-13

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL13 (interleukin 13)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IL13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,957,870 - 20,961,391 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	20,958,464 - 20,961,388 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	19,759,917 - 19,762,847 (+)	NCBI
ROS_Cfam_1.0	11	21,744,389 - 21,747,318 (+)	NCBI
ROS_Cfam_1.0 Ensembl	11	21,744,389 - 21,747,315 (+)	Ensembl
UMICH_Zoey_3.1	11	20,462,871 - 20,465,798 (+)	NCBI
UNSW_CanFamBas_1.0	11	20,310,464 - 20,313,371 (+)	NCBI
UU_Cfam_GSD_1.0	11	20,952,917 - 20,955,847 (+)	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Lung Injury (ISO)

alcoholic hepatitis (ISO)

allergic conjunctivitis (ISO)

allergic disease (ISO)

allergic rhinitis (ISO)

asthma (ISO)

atopic dermatitis (ISO)

autistic disorder (ISO)

autoimmune hepatitis (ISO)

Breast Neoplasms (ISO)

Bronchial Hyperreactivity (ISO)

bronchiolitis obliterans (ISO)

chlamydia (ISO)

Chronic Bronchitis (ISO)

chronic obstructive pulmonary disease (ISO)

contact dermatitis (ISO)

COVID-19 (ISO)

cutaneous leishmaniasis (ISO)

cystic fibrosis (ISO)

Delayed Hypersensitivity (ISO)

dermatitis (ISO)

diffuse scleroderma (ISO)

drug allergy (ISO)

Eczema (ISO)

egg allergy (ISO)

Endotoxemia (ISO)

esophagitis (ISO)

Experimental Arthritis (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Autoimmune Myocarditis (ISO)

extrinsic allergic alveolitis (ISO)

familial adenomatous polyposis 1 (ISO)

Fibrosis (ISO)

food allergy (ISO)

Fungal Lung Diseases (ISO)

Graves' disease (ISO)

hepatitis C (ISO)

Hereditary Neoplastic Syndromes (ISO)

Human Influenza (ISO)

Hyperalgesia (ISO)

Hyperplasia (ISO)

Immediate Hypersensitivity (ISO)

Inflammation (ISO)

invasive ductal carcinoma (ISO)

Kawasaki disease (ISO)

lipoid nephrosis (ISO)

localized scleroderma (ISO)

lung disease (ISO)

Lymphatic Metastasis (ISO)

mastocytosis (ISO)

Metaplasia (ISO)

middle cerebral artery infarction (ISO)

milk allergy (ISO)

multiple sclerosis (ISO)

Mycoplasma pneumoniae pneumonia (ISO)

Nasal Polyps (ISO)

Neurodevelopmental Disorders (ISO)

non-alcoholic fatty liver disease (ISO)

occupational dermatitis (ISO)

onchocerciasis (ISO)

ovarian carcinoma (ISO)

pancreatic cancer (ISO)

pancreatitis (ISO)

peanut allergy (ISO)

peptic esophagitis (ISO)

Perennial Allergic Rhinitis (ISO)

Picornaviridae Infections (ISO)

Plasmodium falciparum malaria (ISO)

pneumonia (ISO)

prostatic hypertrophy (ISO)

Pseudomonas Infections (ISO)

psoriasis (ISO)

psoriatic arthritis (ISO)

pulmonary edema (ISO)

pulmonary emphysema (ISO)

pulmonary eosinophilia (ISO)

pulmonary fibrosis (ISO)

pulmonary hypertension (ISO)

pulmonary tuberculosis (ISO)

purpura (ISO)

Radiation Pneumonitis (ISO)

renal cell carcinoma (ISO)

Reperfusion Injury (ISO)

respiratory allergy (ISO)

Respiratory Sounds (ISO)

respiratory syncytial virus infectious disease (ISO)

Respiratory Tract Granuloma (ISO)

Respiratory Tract Infections (ISO)

rheumatoid arthritis (ISO)

rhinitis (ISO)

Schistosomiasis Mansoni (ISO)

Sepsis (ISO)

sinusitis (ISO)

Sjogren's syndrome (ISO)

systemic lupus erythematosus (ISO)

systemic scleroderma (ISO)

T-Cell Lymphoma (ISO)

Transplant Rejection (ISO)

uveitis (ISO)

vitiligo (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

cannabidiol (EXP)

luteolin (EXP)

masitinib (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to cytokine stimulus (IEA,ISO)

cellular response to mechanical stimulus (ISO)

immune response (IEA)

inflammatory response (IEA,ISO)

macrophage activation (IEA)

microglial cell activation (ISO)

negative regulation of complement-dependent cytotoxicity (IEA)

negative regulation of endothelial cell apoptotic process (IEA)

negative regulation of inflammatory response (IEA)

negative regulation of NAD(P)H oxidase activity (ISO)

negative regulation of neuron death (ISO)

negative regulation of transforming growth factor beta production (ISO)

positive regulation of B cell proliferation (ISO)

positive regulation of cold-induced thermogenesis (IEA)

positive regulation of connective tissue growth factor production (ISO)

positive regulation of gene expression (IEA)

positive regulation of immunoglobulin production (IEA,ISO)

positive regulation of interleukin-10 production (IEA)

positive regulation of ion transport (ISO)

positive regulation of macrophage activation (IEA)

positive regulation of mast cell degranulation (IEA,ISO)

positive regulation of pancreatic stellate cell proliferation (ISO)

positive regulation of protein secretion (ISO)

positive regulation of release of sequestered calcium ion into cytosol (ISO)

positive regulation of smooth muscle cell proliferation (ISO)

positive regulation of tyrosine phosphorylation of STAT protein (ISO)

regulation of proton transport (ISO)

response to ethanol (ISO)

response to lipopolysaccharide (ISO)

response to mechanical stimulus (ISO)

response to nicotine (ISO)

signal transduction (IEA)

Cellular Component

cytoplasm (IEA)

external side of plasma membrane (IEA)

extracellular region (IEA)

extracellular space (IEA,ISO)

Molecular Function

cytokine activity (IEA)

cytokine receptor binding (IEA)

interleukin-13 receptor binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Fc epsilon receptor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:11032397

Genomics

Comparative Map Data

IL13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,957,870 - 20,961,391 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	20,958,464 - 20,961,388 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	19,759,917 - 19,762,847 (+)	NCBI
ROS_Cfam_1.0	11	21,744,389 - 21,747,318 (+)	NCBI
ROS_Cfam_1.0 Ensembl	11	21,744,389 - 21,747,315 (+)	Ensembl
UMICH_Zoey_3.1	11	20,462,871 - 20,465,798 (+)	NCBI
UNSW_CanFamBas_1.0	11	20,310,464 - 20,313,371 (+)	NCBI
UU_Cfam_GSD_1.0	11	20,952,917 - 20,955,847 (+)	NCBI

IL13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	132,656,522 - 132,661,110 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	132,656,263 - 132,661,110 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	131,992,214 - 131,996,802 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	132,021,764 - 132,024,700 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	5	132,021,763 - 132,024,700	NCBI
Celera	5	128,123,995 - 128,126,931 (+)	NCBI
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	127,186,169 - 127,189,105 (+)	NCBI		HuRef
CHM1_1	5	131,427,162 - 131,430,098 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	133,176,323 - 133,180,911 (+)	NCBI

Il13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	53,522,150 - 53,525,529 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	11	53,522,151 - 53,525,529 (-)	Ensembl
GRCm38	11	53,631,323 - 53,634,702 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	53,631,324 - 53,634,702 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	53,444,825 - 53,448,204 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	53,474,747 - 53,478,125 (-)	NCBI			mm8
Celera	11	58,210,849 - 58,214,228 (-)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	31.98	NCBI

Il13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	37,790,130 - 37,792,687 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	10	37,790,130 - 37,792,737 (-)	Ensembl
Rnor_6.0	10	38,982,909 - 38,985,466 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	38,982,909 - 38,985,466 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	38,764,639 - 38,767,196 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	39,093,512 - 39,096,069 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	39,102,758 - 39,105,316 (-)	NCBI
Celera	10	37,134,342 - 37,136,897 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Il13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955408	4,046,406 - 4,049,795 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	134,235,788 - 134,240,548 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	134,235,788 - 134,240,548 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	5	128,073,863 - 128,078,453 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

Il13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	115,527,018 - 115,529,671 (-)	NCBI
SpeTri2.0	NW_004936647	2,529,933 - 2,532,503 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	134,972,623 - 134,975,093 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	134,972,099 - 134,976,672 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	140,441,025 - 140,444,068 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	35,475,762 - 35,479,419 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	23	35,476,490 - 35,478,869 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666034	42,463,847 - 42,466,277 (-)	NCBI	Vero_WHO_p1.0

Il13
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	39,428,095 - 39,429,843 (-)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624733	39,427,189 - 39,430,019 (-)	NCBI	HetGla_female_1.0		hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium			1	1		1
Low			8	5	4	5	1				6	1
Below cutoff	4	5	10		2		5	2	8	8	3	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022424906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022424907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF244915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000001364 ⟹ ENSCAFP00000001250

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	11	20,958,464 - 20,961,388 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845019361 ⟹ ENSCAFP00845015137

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	21,744,389 - 21,747,315 (+)	Ensembl

RefSeq Acc Id:

NM_001003384 ⟹ NP_001003384

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,958,464 - 20,961,391 (+)	NCBI
Dog10K_Boxer_Tasha	11	19,759,917 - 19,762,847 (+)	NCBI
ROS_Cfam_1.0	11	21,744,389 - 21,747,318 (+)	NCBI
UMICH_Zoey_3.1	11	20,462,871 - 20,465,798 (+)	NCBI
UNSW_CanFamBas_1.0	11	20,310,464 - 20,313,371 (+)	NCBI
UU_Cfam_GSD_1.0	11	20,952,917 - 20,955,847 (+)	NCBI

Sequence:

show sequence

CTACGACCTGCCTGCTCTTCCCTCGCTCCTCCTGCATTGGCTCTGGGCTCCATGGCGCTCTGGT
TGACTGTGGTCATTGCTCTCACCTGCCTCGGTGGCCTTGCCTCCCCGAGCCCTGTGACTCCCTC
CCCAACCCTCAAGGAGCTCATTGAGGAGCTGGTCAACATCACCCAGAATCAGGCATCCCTCTGC
AACGGCAGCATGGTGTGGAGCGTCAACCTGACCGCCGGCATGTACTGCGCAGCTCTAGAATCTC
TGATCAATGTCTCCGACTGCAGCGCCATCCAAAGGACCCAGAGGATGCTGAAAGCACTGTGCTC
TCAAAAGCCCGCGGCAGGGCAGATTTCCAGTGAACGCAGCCGAGACACCAAAATTGAAGTGATC
CAGTTGGTGAAAAACCTGCTCACCTATGTAAGGGGAGTTTATCGCCATGGAAATTTCAGATGAA
GCATGAAAACTTAGCATCCTTATCTGTAGACCCAGACCTGACCACTTAAGTTCCAGATTCATTT
TTCTTTCCGACGTCACAAATTTCTTAGGGAGGTGGGGGGGGGGGAGAACCATTTCCTCAGCTGG
GACCTCAGCCTGCACCGCCTGCCTCCATGGAGCTGAGCCCAGCCACCCCTGCCTTGGTGCATGG
GGCCCAGCCGGGTGGCCCTCCTCCGTCTGCACTTCATCAACGCTGAGGGAAAGCACTGCATCCC
ATGACTGTCCCCTCCTCAGAGCAAAGTGCAGCATTACAGTGGAGGCAGATATGTGTGGGAGGGG
GTCTTGCTGTACCTGGGAGTGGCACAGACATGTTTCTTCTTAGCCTTATTTATTATTGTGTGTT
ATTTAAACAAGTGTCTTTGTTTGTGCTGGGGACAGGGAGTGGCTTGGAGCTGGGGGCCCAGTGA
CTCGGGTTTAGAGAGTCCCTGGGAATAAGCACTGTGTGTAAAATTCTGCTACCTCACTGGGATC
CTGGGGCCGACACAGGGGACAGGAGAAAGGGTCAGAGATGCTGCTCTTGTCTGCCACTCAGCAG
CTGGCCCTCAGCCAAGCAGTAATTTATTGTTTTTCCTTGTATTTAAAGTTAAGAAATAAAATAT
GTTATCAAAGAGTTAATAATATATAGAAGAGTAGCCTAAAAGGCTGCATTTGGTGTGTGTGGCC
AGGCCGGGGCGGGTGGGGGGGAGGGTGTTGTCACTGAATGTGCTCTTTCACTGACTTTGTCAAA
CTGGAAGCCAGAAATAAAGATGGTGACAAGAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003384	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF63204	(Get FASTA)	NCBI Sequence Viewer
	Q9N0W9	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001003384 ⟸ NM_001003384
- Peptide Label:	precursor
- UniProtKB:	Q9N0W9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALWLTVVIALTCLGGLASPSPVTPSPTLKELIEELVNITQNQASLCNGSMVWSVNLTAGMYCA ALESLINVSDCSAIQRTQRMLKALCSQKPAAGQISSERSRDTKIEVIQLVKNLLTYVRGVYRHG NFR hide sequence

RefSeq Acc Id:

ENSCAFP00000001250 ⟸ ENSCAFT00000001364

RefSeq Acc Id:

ENSCAFP00845015137 ⟸ ENSCAFT00845019361

Promoters

RGD ID:

13685171

Promoter ID:

EPDNEW_C3239

Type:

single initiation site

Name:

IL13_1

Description:

interleukin 13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,958,442 - 20,958,502	EPDNEW

Damaging Variants

Assembly: CanFam3.1

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
11	20960082	20960083	A	G	snv	Australian Cattle dog (AC023), Australian Cattle dog (AC108), Alpine Dachsbracke (AD009), Yorkshire Terrier (YT003), Australian Shepherd (AU178), Bavarian Hound (BG064), Miniature Bullterrier (BT007), Bullterrier (BT012), Cocker Spaniel (CP003), Great Dane (DD116), Dachshund (DH098), Dachshund (DH126), Chinese indigenous dogs (DQ1), Chinese indigenous dogs (DQ10), Chinese indigenous dogs (DQ2), Chinese indigenous dogs (DQ4), Chinese indigenous dogs (DQ5), Chinese indigenous dogs (DQ6), Chinese indigenous dogs (DQ7), Chinese indigenous dogs (DQ8), Chinese indigenous dogs (DQ9), German Shepherd/Mixed breed (DS032), German Shepherd/Mixed breed (DS041), German Shepherd/Mixed breed (DS042), Entlebucher Sennenhund (EN091), Entlebucher Sennenhund (EN154), Entlebucher Sennenhund (EN221), Entlebucher Sennenhund (EN247), Entlebucher Sennenhund (EN261), Entlebucher Sennenhund (EN262), Entlebucher Sennenhund (EN263), Entlebucher Sennenhund (EN264), French Bulldog (FB065), Golden Retriever (GR1078), German Wirehaired (GW004), Greyhound (GY432), Jack Russell Terrier (JR0034), German Hunting Terrier (JT007), Jagdterrier (JT011), Kromfohrländer (KF042), Kunming Dog (KM10), Leonberger (LB1919), Chinese indigenous dogs (LJ9), Landseer (LN048), Norwich Terrier (NW206), Norwich Terrier (NW255), Spanish Water Dog (PE002), Poodle (PL116), Rottweiler (RO2), Rhodesian Ridgeback (RR098), Rhodesian Ridgeback (RR123), Rhodesian Ridgeback (RR224), Sloughi (SG005), Sloughi (SG006), Sloughi (SG008), Greater Swiss Mountain Dog (SH008), Pembroke Welsh Corgi (SRS732551), Black Russian Terrier (SRS833812), Shetland Sheepdog (SRS932138), Alaskan Husky (SY001), Siberian Husky (SY046), Tibetan Mastiff (TM2), Tibetan Mastiff (TM5), Tibetan Mastiff (TM7), Tibetan Mastiff (TM9), Weimaraner (WE008), Whippet (WH083), West Highland White Terrier (WW174), West Highland White Terrier (WW361), West Highland White Terrier (WW362), West Highland White Terrier (WW363), West Highland White Terrier (WW364)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000000878	Ensembl
	ENSCAFG00030011676	UniProtKB/Swiss-Prot
	ENSCAFG00040006314	UniProtKB/TrEMBL
	ENSCAFG00845010953	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSCAFP00030018820	UniProtKB/Swiss-Prot
	ENSCAFP00040010202	UniProtKB/TrEMBL
	ENSCAFP00040010219	UniProtKB/TrEMBL
	ENSCAFP00845015137	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00030021587	UniProtKB/Swiss-Prot
	ENSCAFT00040011771	UniProtKB/TrEMBL
	ENSCAFT00040011792	UniProtKB/TrEMBL
	ENSCAFT00845019361	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1250.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	4_helix_cytokine-like_core	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-4/IL-13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL-4/IL-13_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:442990	UniProtKB/Swiss-Prot
NCBI Gene	IL13	ENTREZGENE
Pfam	IL13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	INTRLEUKIN13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	INTERLEUKIN_4_13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	IL4_13	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47266	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0QE97_CANLF	UniProtKB/TrEMBL
	A0A8C0RZ01_CANLF	UniProtKB/TrEMBL
	IL13_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:41936	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Disease Annotations - OMIM

Imported Annotations - SMPDB