IL13 (interleukin 13) - Rat Genome Database

Name: IL13
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: IL13 (interleukin 13) Canis lupus familiaris

Analyze

General
Array IDs
References

Symbol:

IL13

Name:

interleukin 13

Description:

null

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

IL-13; interleukin-13

Orthologs:

Homo sapiens (human) : IL13 (interleukin 13) HGNC Alliance
Mus musculus (house mouse) : Il13 (interleukin 13) MGI Alliance
Rattus norvegicus (Norway rat) : Il13 (interleukin 13) Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il13 (interleukin 13)
Pan paniscus (bonobo/pygmy chimpanzee) : IL13 (interleukin 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il13 (interleukin 13)
Sus scrofa (pig) : IL13 (interleukin 13)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL13 (interleukin 13)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL13 (interleukin 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,957,870 - 20,961,391 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog Cytomap	11		NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Disease Annotations

RGD Manual Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acute Lung Injury		ISS	RGD:69008	9068941	mRNA:increased expression:lung	RGD	PMID:15461830 REF_RGD_ID:4145512
alcoholic hepatitis		ISS	RGD:69008	9068941	mRNA:increased expression:liver	RGD	PMID:16698589 REF_RGD_ID:1581860
allergic conjunctivitis		ISS	RGD:69008	9068941	associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:22023794 REF_RGD_ID:8549595
allergic conjunctivitis		ISS	RGD:69008	9068941		RGD	PMID:9191598 REF_RGD_ID:8549533
allergic hypersensitivity disease		ISS	RGD:69008	9068941	DNA:SNP:promoter, 3' utr:-1055C>T, 4738G>A (human)	RGD	PMID:11588017 REF_RGD_ID:4765128
allergic rhinitis		ISS	RGD:69008	9068941	DNA:SNPs:CDS:p.R130Q (rs20541) (human)	RGD	PMID:22852128 REF_RGD_ID:8549518
allergic rhinitis		ISS	RGD:69008	9068941	DNA:SNP:promoter:-1512A>C (human)	RGD	PMID:23996716 REF_RGD_ID:8549501
allergic rhinitis	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism:exon:c. 2044G>A (human)	RGD	PMID:17091279 REF_RGD_ID:4152796
allergic rhinitis	no_association	ISS	RGD:69008	9068941	DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:12928861 REF_RGD_ID:8549516
asthma	severity	ISS	RGD:69008	9068941	protein:increased expression:sputum	RGD	PMID:18328894 REF_RGD_ID:4145777
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphisms: :rs20541, rs1295685(human)	RGD	PMID:20484924 REF_RGD_ID:4145534
asthma		ISS	RGD:69008	9068941	mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid	RGD	PMID:18222984 REF_RGD_ID:2307110
asthma	severity	ISS	RGD:69008	9068941	DNA:polymorphism: :c.-1055C>T (human)	RGD	PMID:20198887 REF_RGD_ID:4145593
asthma		ISS	RGD:69008	9068941		RGD	PMID:16120094 REF_RGD_ID:4206706
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism: :p. R110Q (human)	RGD	PMID:15315330 REF_RGD_ID:4321828
asthma		ISS	RGD:69008	9068941	DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)	RGD	PMID:17006604 REF_RGD_ID:4892639
asthma	severity	ISS	RGD:69008	9068941		RGD	PMID:18258919 REF_RGD_ID:4145639
asthma	no_association	ISS	RGD:69008	9068941	DNA:polymorphism:cds:p.R130Q (human)	RGD	PMID:11678850 REF_RGD_ID:4763761
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism: :c. 1923C>T (human)	RGD	PMID:19575932 REF_RGD_ID:4145775
asthma		ISS	RGD:69008	9068941	associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)	RGD	PMID:23317483 REF_RGD_ID:8549509
asthma		ISS	RGD:69008	9068941		RGD	PMID:12604708 REF_RGD_ID:2301686
asthma		ISS	RGD:69008	9068941	DNA:SNP: :c. -646A>G (human)	RGD	PMID:17303794 REF_RGD_ID:4146241
asthma	severity	ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:11758895 REF_RGD_ID:4763153
asthma		ISS	RGD:69008	9068941	DNA:polymorphism: :c. 2044G>A (human)	RGD	PMID:18341619 REF_RGD_ID:4145776
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism:promoter:c. -1055C>T (human)	RGD	PMID:16024972 REF_RGD_ID:4220633
asthma		ISS	RGD:69008	9068941		RGD	PMID:12091879 REF_RGD_ID:4145664
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism:3'utr:c.4738G>A (human)	RGD	PMID:11588017 REF_RGD_ID:4765128
asthma		ISS	RGD:69008	9068941		RGD	PMID:20819635 REF_RGD_ID:4145453
asthma	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)	RGD	PMID:19796199 REF_RGD_ID:4145601
asthma		ISS	RGD:69008	9068941		RGD	PMID:16393274 REF_RGD_ID:4145508
atopic dermatitis	treatment	ISS	RGD:69008	9068941		RGD	PMID:19006098 REF_RGD_ID:8549531
atopic dermatitis		ISS	RGD:69008	9068941	DNA:SNP:exon:4257G>A (human)	RGD	PMID:10887320 REF_RGD_ID:8549529
atopic dermatitis	severity	ISS	RGD:69008	9068941	DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)	RGD	PMID:23317483 REF_RGD_ID:8549509
atopic dermatitis		ISS	RGD:69008	9068941	DNA:SNPs: :rs3091307, rs20541 (human)	RGD	PMID:21913997 REF_RGD_ID:5684364
atopic dermatitis		ISS	RGD:69008	9068941		RGD	PMID:16672002 REF_RGD_ID:8549583
atopic dermatitis	severity	ISS	RGD:69008	9068941		RGD	PMID:17313488 REF_RGD_ID:8549539
Breast Neoplasms	susceptibility	ISS	RGD:69008	9068941	DNA:SNPs, haplotypes:promoter, exon:-1512A>C, -1055C>T, 2044G>A (human)	RGD	PMID:18989750 REF_RGD_ID:8549503
Breast Neoplasms	treatment	ISS	RGD:69008	9068941		RGD	PMID:17438063 REF_RGD_ID:8549557
Bronchial Hyperreactivity		ISS	RGD:69008	9068941		RGD	PMID:12669034 REF_RGD_ID:4761594
Bronchial Hyperreactivity	susceptibility	ISS	RGD:69008	9068941	DNA:SNP:promoter:-1055C>T (human)	RGD	PMID:11588017 REF_RGD_ID:4765128
Bronchial Hyperreactivity		ISS	RGD:69008	9068941	associated with Eosinophilic enteropathy	RGD	PMID:15236177 REF_RGD_ID:4145432
bronchiolitis obliterans		ISS	RGD:69008	9068941	protein:increased expression:bronchoalveolar lavage fluid	RGD	PMID:17182591 REF_RGD_ID:4146242
Bronchitis, Chronic		ISS	RGD:69008	9068941	protein:increased expression:Respiratory Mucosa	RGD	PMID:14582911 REF_RGD_ID:4759835
chlamydia		ISS	RGD:69008	9068941		RGD	PMID:21573182 REF_RGD_ID:5684365
chronic obstructive pulmonary disease	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism:promoter:c.-1055C>T (human)	RGD	PMID:19995275 REF_RGD_ID:4145596
chronic obstructive pulmonary disease	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphisms:intron1,exon4s: rs2066960, rs20541, rs1295685 (human)	RGD	PMID:19796199 REF_RGD_ID:4145601
chronic obstructive pulmonary disease	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism: :c. 1103C>T (human)	RGD	PMID:15308043 REF_RGD_ID:4145668
chronic obstructive pulmonary disease	no_association	ISS	RGD:69008	9068941	DNA:SNP:promoter:c.-1055 C>T (human)	RGD	PMID:15820084 REF_RGD_ID:4145714
contact dermatitis	treatment	ISS	RGD:69008	9068941		RGD	PMID:19951958 REF_RGD_ID:8549563
cutaneous leishmaniasis	treatment	ISS	RGD:69008	9068941		RGD	PMID:12739821 REF_RGD_ID:8549536
cutaneous leishmaniasis	treatment	ISS	RGD:69008	9068941		RGD	PMID:18924210 REF_RGD_ID:8549561
cystic fibrosis		ISS	RGD:69008	9068941	mRNA:increased expression:bronchoalveolar lavage fluid	RGD	PMID:15463872 REF_RGD_ID:4312589
Delayed Hypersensitivity	treatment	ISS	RGD:69008	9068941		RGD	PMID:19951958 REF_RGD_ID:8549563
dermatitis		ISS	RGD:69008	9068941	DNA:SNP:promoter:rs20541 (human)	RGD	PMID:23171465 REF_RGD_ID:8549505
Eczema		ISS	RGD:69008	9068941	DNA:SNP:CDS:p.R130Q (rs20541) (human)	RGD	PMID:23815671 REF_RGD_ID:8549530
Eczema	no_association	ISS	RGD:69008	9068941	DNA:polymorphisms: :multiple	RGD	PMID:18410415 REF_RGD_ID:8549512
egg allergy		ISS	RGD:69008	9068941	associated with Dermatitis, Atopic; DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:19220774 REF_RGD_ID:8549541
Endotoxemia	treatment	ISS	RGD:69008	9068941		RGD	PMID:10674721 REF_RGD_ID:8549626
esophagitis		ISS	RGD:69008	9068941		RGD	PMID:20543112 REF_RGD_ID:4145528
Experimental Arthritis	treatment	ISS	RGD:69008	9068941		RGD	PMID:11860705 REF_RGD_ID:8549606
Experimental Arthritis		ISS	RGD:69008	9068941		RGD	PMID:17665443 REF_RGD_ID:4889497
Experimental Autoimmune Encephalomyelitis	severity	ISS	RGD:69008	9068941		RGD	PMID:18250480 REF_RGD_ID:5684366
Experimental Autoimmune Encephalomyelitis		ISS	RGD:69008	9068941		RGD	PMID:7523520 REF_RGD_ID:5684367
Experimental Autoimmune Myocarditis	treatment	ISS	RGD:69008	9068941		RGD	PMID:15902684 REF_RGD_ID:8549607
extrinsic allergic alveolitis		ISS	RGD:69008	9068941		RGD	PMID:9916735 REF_RGD_ID:4145650
extrinsic allergic alveolitis		ISS	RGD:69008	9068941	mRNA:increased expression:lung	RGD	PMID:20861649 REF_RGD_ID:5128548
Fibrosis	treatment	ISS	RGD:69008	9068941	associated with Venous Thrombosis	RGD	PMID:12947342 REF_RGD_ID:8549644
food allergy		ISS	RGD:69008	9068941	mRNA:increased expression:small intestine	RGD	PMID:22038918 REF_RGD_ID:5684372
Fungal Lung Diseases		ISS	RGD:69008	9068941	protein:increased expression:lung	RGD	PMID:19752036 REF_RGD_ID:4145474
Fungal Lung Diseases		ISS	RGD:69008	9068941	protein:increased expression:lung	RGD	PMID:16544260 REF_RGD_ID:4145506
Graves' disease	disease_progression	ISS	RGD:69008	9068941	DNA:SNP:promoter:-1112C>T (rs1800925) (human)	RGD	PMID:21235536 REF_RGD_ID:7829719
Graves' disease	susceptibility	ISS	RGD:69008	9068941	DNA:SNPs:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:15483090 REF_RGD_ID:8549544
Human Influenza		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:20003352 REF_RGD_ID:4888530
Hyperalgesia	treatment	ISS	RGD:69008	9068941		RGD	PMID:11399514 REF_RGD_ID:8549555
invasive ductal carcinoma		ISS	RGD:69008	9068941	protein:increased expression:breast	RGD	PMID:22135852 REF_RGD_ID:8549515
Kawasaki disease		ISS	RGD:69008	9068941		RGD	PMID:21958311 REF_RGD_ID:5684363
lipoid nephrosis		ISS	RGD:69008	9068941		RGD	PMID:17429054 REF_RGD_ID:2290347
localized scleroderma		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:12920362 REF_RGD_ID:8549537
lung disease		ISS	RGD:69008	9068941	acute lung injury	RGD	PMID:17404281 REF_RGD_ID:4145647
lung disease		ISS	RGD:69008	9068941	associated with Behcet Syndrome; more ...	RGD	PMID:20716936 REF_RGD_ID:4145526
Lymphatic Metastasis		ISS	RGD:69008	9068941	associated with Melanoma, Cutaneous Malignant;mRNA:increased expression:lymph node	RGD	PMID:17545514 REF_RGD_ID:8549587
mastocytosis		ISS	RGD:69008	9068941	DNA:SNP:promoter:-1112C>T (rs1800925) (human)	RGD	PMID:19178408 REF_RGD_ID:8549523
middle cerebral artery infarction		ISS	RGD:69008	9068941	protein:increased expression:cerebral cortex	RGD	PMID:23028794 REF_RGD_ID:7204480
milk allergy		ISS	RGD:69008	9068941	associated with Dermatitis, Atopic; DNA:SNP:CDS:p.R130Q (rs20541) (human)	RGD	PMID:19220774 REF_RGD_ID:8549541
multiple sclerosis		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:22031307 REF_RGD_ID:5684368
multiple sclerosis	severity	ISS	RGD:69008	9068941	protein:increased expression:cerebrospinal fluid	RGD	PMID:21677024 REF_RGD_ID:8549589
Mycoplasma pneumoniae pneumonia		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:20416219 REF_RGD_ID:4145765
Nasal Polyps		ISS	RGD:69008	9068941	associated with Rhinosinusitis;protein:increased expression:serum	RGD	PMID:23969075 REF_RGD_ID:8549540
nonalcoholic fatty liver disease		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:18802068 REF_RGD_ID:4145478
occupational dermatitis		ISS	RGD:69008	9068941		RGD	PMID:19254288 REF_RGD_ID:8549579
onchocerciasis	severity	ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:22805723 REF_RGD_ID:8549600
ovarian carcinoma		ISS	RGD:69008	9068941	mRNA,protein:increased expression:tumor,ascites:mRNA increased relative to normal ovary, protein increased in tumor tissue/cancer ascites relative to normal ovary/ascites	RGD	PMID:14984938 REF_RGD_ID:2290344
pancreatic cancer	disease_progression	ISS	RGD:69008	9068941	protein:increased expression:pancreas	RGD	PMID:18758789 REF_RGD_ID:2317669
pancreatic cancer		ISS	RGD:69008	9068941		RGD	PMID:12808442 REF_RGD_ID:2317670
pancreatitis		ISS	RGD:69008	9068941	protein:increased expression:pancreas	RGD	PMID:20100461 REF_RGD_ID:4145466
peanut allergy		ISS	RGD:69008	9068941	associated with Dermatitis, Atopic; DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:19220774 REF_RGD_ID:8549541
peptic esophagitis		ISS	RGD:69008	9068941	associated with asthma; more ...	RGD	PMID:18222984 REF_RGD_ID:2307110
Perennial Allergic Rhinitis		ISS	RGD:69008	9068941	mRNA, protein:increased expression:nasal mucosa	RGD	PMID:8520776 REF_RGD_ID:4782826
Picornaviridae Infections		ISS	RGD:69008	9068941	associated with Pulmonary Disease, Chronic Obstructive;mRNA, protein:increased expression:lung	RGD	PMID:19748999 REF_RGD_ID:4145626
Plasmodium falciparum malaria		ISS	RGD:69008	9068941	protein:increased expression:plasma	RGD	PMID:21985368 REF_RGD_ID:5684362
pneumonia		ISS	RGD:69008	9068941	associated with Respiratory Distress Syndrome, Newborn; more ...	RGD	PMID:19695190 REF_RGD_ID:4145774
prostatic hypertrophy		ISS	RGD:69008	9068941	mRNA:increased expression:prostate gland	RGD	PMID:20945403 REF_RGD_ID:5684375
Pseudomonas Infections		ISS	RGD:69008	9068941	associated with Cystic Fibrosis	RGD	PMID:16387607 REF_RGD_ID:4145500
psoriasis	susceptibility	ISS	RGD:69008	9068941	DNA:missense mutation:cds: (rs20541) (human)	RGD	PMID:23617596 REF_RGD_ID:8549593
psoriasis	no_association	ISS	RGD:69008	9068941	DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:21349879 REF_RGD_ID:8549517
psoriatic arthritis	susceptibility	ISS	RGD:69008	9068941	DNA:SNPs:promoter, exon:rs1800925, rs20541, rs848 (human)	RGD	PMID:19554022 REF_RGD_ID:8549552
psoriatic arthritis	susceptibility	ISS	RGD:69008	9068941	DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:21349879 REF_RGD_ID:8549517
pulmonary edema		ISS	RGD:69008	9068941	aosciated with Enterovirus Infections	RGD	PMID:15635619 REF_RGD_ID:4145737
pulmonary emphysema		ISS	RGD:69008	9068941		RGD	PMID:11067861 REF_RGD_ID:4145652
pulmonary eosinophilia		ISS	RGD:69008	9068941	associated with Respiratory Syncytial Virus Infections	RGD	PMID:12574374 REF_RGD_ID:8549597
pulmonary fibrosis	treatment	ISS	RGD:69008	9068941		RGD	PMID:19154443 REF_RGD_ID:2314537
pulmonary fibrosis		ISS	RGD:69008	9068941		RGD	PMID:20176803 REF_RGD_ID:4888529
pulmonary fibrosis		ISS	RGD:69008	9068941	idiopathic pulmonary fibrosis	RGD	PMID:19654941 REF_RGD_ID:4145627
pulmonary hypertension		ISS	RGD:69008	9068941	associated with sclerosis; more ...	RGD	PMID:19799786 REF_RGD_ID:4145600
pulmonary hypertension		ISS	RGD:69008	9068941	associated with Scleroderma, Limited;protein:increased expression:plasma	RGD	PMID:21425123 REF_RGD_ID:8549528
pulmonary tuberculosis		ISS	RGD:69008	9068941	mRNA:increased expression:Leukocytes, Mononuclear	RGD	PMID:10608794 REF_RGD_ID:4145649
purpura	susceptibility	ISS	RGD:69008	9068941	associated withe Sjogren's Syndrome;DNA:SNP:cds:2044 G>A(human)	RGD	PMID:16166103 REF_RGD_ID:11528572
Radiation Pneumonitis	susceptibility	ISS	RGD:69008	9068941	associated with carcinoma, non-small-cell lung; more ...	RGD	PMID:20811626 REF_RGD_ID:5131286
Reperfusion Injury		ISS	RGD:69008	9068941	protein:decreased expression:plasma	RGD	PMID:18354382 REF_RGD_ID:2301685
respiratory allergy		ISS	RGD:69008	9068941	mRNA:increased expression:lung	RGD	PMID:19564030 REF_RGD_ID:4145637
respiratory allergy	susceptibility	ISS	RGD:69008	9068941	DNA:SNP, missense mutation:promoter, exon:-1112C>T, p.R130Q (human)	RGD	PMID:18849614 REF_RGD_ID:8549507
Respiratory Sounds		ISS	RGD:69008	9068941	associated with Bronchiolitis; more ...	RGD	PMID:18312531 REF_RGD_ID:4145779
respiratory syncytial virus infectious disease		ISS	RGD:69008	9068941		RGD	PMID:18250447 REF_RGD_ID:4145641
Respiratory Tract Granuloma	treatment	ISS	RGD:69008	9068941		RGD	PMID:10857756 REF_RGD_ID:8549624
Respiratory Tract Infections		ISS	RGD:69008	9068941	Severe Acute Respiratory Syndrome	RGD	PMID:14633438 REF_RGD_ID:4145665
rheumatoid arthritis		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:12051401 REF_RGD_ID:8549582
rhinitis	susceptibility	ISS	RGD:69008	9068941	associated with asthma; more ...	RGD	PMID:20358028 REF_RGD_ID:4145767
rhinitis	susceptibility	ISS	RGD:69008	9068941	DNA:polymorphism: :rs1800925 (human)	RGD	PMID:20484924 REF_RGD_ID:4145534
rhinitis		ISS	RGD:69008	9068941	mRNA:increased expression:nose	RGD	PMID:20696593 REF_RGD_ID:4145454
rhinitis		ISS	RGD:69008	9068941		RGD	PMID:16120094 REF_RGD_ID:4206706
rhinitis	disease_progression	ISS	RGD:69008	9068941		RGD	PMID:17088137 REF_RGD_ID:4159171
Schistosomiasis Mansoni	treatment	ISS	RGD:69008	9068941		RGD	PMID:10903803 REF_RGD_ID:8549615
Sepsis		ISS	RGD:69008	9068941		RGD	PMID:10679115 REF_RGD_ID:4145654
Sepsis		ISS	RGD:69008	9068941	protein:decreased expression:ileum	RGD	PMID:21159497 REF_RGD_ID:8549643
sinusitis	susceptibility	ISS	RGD:69008	9068941	associated with asthma; more ...	RGD	PMID:20358028 REF_RGD_ID:4145767
Sjogren's syndrome		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:12051401 REF_RGD_ID:8549582
systemic lupus erythematosus		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:12051401 REF_RGD_ID:8549582
systemic scleroderma		ISS	RGD:69008	9068941	protein:increased expression:serum	RGD	PMID:9034992 REF_RGD_ID:5684371
systemic scleroderma	no_association	ISS	RGD:69008	9068941	DNA:SNPs:promoter, CDS:-1112C>T (rs1800925), p.R130Q (rs20541) (human)	RGD	PMID:22045834 REF_RGD_ID:8549502
systemic scleroderma		ISS	RGD:69008	9068941	DNA:SNPs: :rs1800925, rs2243204 (human)	RGD	PMID:16832637 REF_RGD_ID:5684369
systemic scleroderma		ISS	RGD:69008	9068941	mRNA, protein:increased expression:skin	RGD	PMID:15564778 REF_RGD_ID:5684370
T-Cell Lymphoma		ISS	RGD:69008	9068941		RGD	PMID:19951958 REF_RGD_ID:8549563
Transplant Rejection		ISS	RGD:69008	9068941	mRNA:increased expression:liver	RGD	PMID:17532783 REF_RGD_ID:10402939
Transplant Rejection	treatment	ISS	RGD:69008	9068941		RGD	PMID:17902182 REF_RGD_ID:8549629
Transplant Rejection	treatment	ISS	RGD:69008	9068941		RGD	PMID:17331844 REF_RGD_ID:8549647
uveitis	treatment	ISS	RGD:69008	9068941		RGD	PMID:11481267 REF_RGD_ID:8549551
uveitis		ISS	RGD:69008	9068941		RGD	PMID:17392164 REF_RGD_ID:4145496
vitiligo	treatment	ISS	RGD:69008	9068941		RGD	PMID:23680073 REF_RGD_ID:8549591

Imported Annotations - ClinVar

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
asthma		ISS	RGD:69008	9068941	ClinVar Annotator: match by term: Asthma, susceptibility to	ClinVar
Hereditary Neoplastic Syndromes		ISS	RGD:69008	9068941	ClinVar Annotator: match by term: Hereditary cancer-predisposing syndrome	ClinVar	PMID:28492532

Imported Annotations - CTD

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
allergic hypersensitivity disease		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21625544
allergic rhinitis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD
asthma		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22867017
atopic dermatitis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18249437 PMID:22355542
autistic disorder		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:16360218
autoimmune hepatitis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21227906
Bronchial Hyperreactivity		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:12654629 PMID:23434795
drug allergy		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20485159
Experimental Arthritis		ISS	RGD:69008	9068941	CTD Direct Evidence: therapeutic	CTD	PMID:10444273
Hyperplasia		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19342650
Immediate Hypersensitivity		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20485159 PMID:22967010
Inflammation		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22867017
lung disease		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22355542
Metaplasia		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21203431
pneumonia		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21625544
psoriasis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:19169254 PMID:20953190
pulmonary fibrosis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:15322207
renal cell carcinoma		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22317767
sinusitis		ISS	RGD:69008	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:20358028

Imported Annotations - OMIM

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
allergic rhinitis	susceptibility	ISO	RGD:69008	7240710		OMIM
allergic rhinitis	susceptibility	ISS	RGD:69008	9068941		OMIM
asthma	susceptibility	ISS	RGD:69008	9068941		OMIM
asthma	susceptibility	ISO	RGD:69008	7240710		OMIM

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cellular response to mechanical stimulus		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
cytokine-mediated signaling pathway		ISS	RGD:69008	9068941		Reactome	Reactome:R-HSA-6785807
immune response		IEA	InterPro:IPR001325\|InterPro:IPR018096	13508589		InterPro	GO_REF:0000002
immune response		ISS	RGD:69008	9068941		InterPro	GO_REF:0000002
inflammatory response		ISS	RGD:69008	9068941		PINC	PMID:8096327
microglial cell activation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
negative regulation of complement-dependent cytotoxicity		ISS	RGD:69008	9068941		AgBase	PMID:16034134
negative regulation of endothelial cell apoptotic process		ISS	RGD:69008	9068941		AgBase	PMID:16034134
negative regulation of lung ciliated cell differentiation		ISS	RGD:69008	9068941		BHF-UCL	PMID:20539013
negative regulation of NAD(P)H oxidase activity		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
negative regulation of neuron death		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
negative regulation of transforming growth factor beta production		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of B cell proliferation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of cold-induced thermogenesis		ISS	RGD:69008	9068941		YuBioLab	PMID:24906148
positive regulation of connective tissue growth factor production		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of gene expression		ISS	RGD:69008	9068941		ARUK-UCL	PMID:12574355
positive regulation of gene expression		ISS	RGD:69008	9068941		ARUK-UCL	GO_REF:0000024
positive regulation of immunoglobulin production		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of lung goblet cell differentiation		ISS	RGD:69008	9068941		BHF-UCL	PMID:20539013
positive regulation of macrophage activation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of mast cell degranulation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of pancreatic stellate cell proliferation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of protein secretion		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of release of sequestered calcium ion into cytosol		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of smooth muscle cell proliferation		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
positive regulation of tyrosine phosphorylation of STAT protein		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
regulation of proton transport		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
response to ethanol		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
response to lipopolysaccharide		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
response to nicotine		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
signal transduction		IEA	GO:0005125	13508589		GOC	GO_REF:0000108

Cellular Component

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cytoplasm		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
external side of plasma membrane		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
extracellular region		ISS	RGD:69008	9068941		Reactome	Reactome:R-HSA-449818 more ...
extracellular region		ISS	RGD:69008	9068941		BHF-UCL	PMID:20041150
extracellular region		ISS	RGD:69008	9068941		InterPro	GO_REF:0000002
extracellular space		IEA	UniProtKB-KW:KW-0202	13508589		UniProtKB	GO_REF:0000037
extracellular space		ISS	RGD:69008	9068941		UniProtKB	PMID:16275384

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cytokine activity		IEA	UniProtKB-KW:KW-0202	13508589		UniProtKB	GO_REF:0000037
cytokine activity		ISS	RGD:69008	9068941		UniProtKB	GO_REF:0000037
cytokine receptor binding		IEA	InterPro:IPR001325\|InterPro:IPR018096	13508589		InterPro	GO_REF:0000002
cytokine receptor binding		ISS	RGD:69008	9068941		InterPro	GO_REF:0000002
interleukin-13 receptor binding		ISS	RGD:69008	9068941		Ensembl	GO_REF:0000107
protein binding		ISS	RGD:69008	9068941		IntAct	PMID:18243101 PMID:20223216
protein binding		ISS	RGD:69008	9068941		IntAct	PMID:20223216 PMID:27629921

Molecular Pathway Annotations

Imported Annotations - SMPDB

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Fc epsilon receptor mediated signaling pathway		ISS	RGD:69008	9068941		SMPDB	SMP:00358

Imported Annotations - KEGG (archival)

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
asthma pathway		ISS	RGD:69008	9068941		KEGG	hsa:05310
Jak-Stat signaling pathway		ISS	RGD:69008	9068941		KEGG	hsa:04630
measles pathway		ISS	RGD:69008	9068941		KEGG	hsa:05162

Disease Annotations

	Acute Lung Injury (ISS)
	alcoholic hepatitis (ISS)
	allergic conjunctivitis (ISS)
	allergic hypersensitivity disease (ISS)
	allergic rhinitis (ISO,ISS)
	asthma (ISO,ISS)
	atopic dermatitis (ISS)
	autistic disorder (ISS)
	autoimmune hepatitis (ISS)
	Breast Neoplasms (ISS)
	Bronchial Hyperreactivity (ISS)
	bronchiolitis obliterans (ISS)
	Bronchitis, Chronic (ISS)
	chlamydia (ISS)
	chronic obstructive pulmonary disease (ISS)
	contact dermatitis (ISS)
	cutaneous leishmaniasis (ISS)
	cystic fibrosis (ISS)
	Delayed Hypersensitivity (ISS)
	dermatitis (ISS)
	drug allergy (ISS)
	Eczema (ISS)
	egg allergy (ISS)
	Endotoxemia (ISS)
	esophagitis (ISS)
	Experimental Arthritis (ISS)
	Experimental Autoimmune Encephalomyelitis (ISS)
	Experimental Autoimmune Myocarditis (ISS)
	extrinsic allergic alveolitis (ISS)
	Fibrosis (ISS)
	food allergy (ISS)
	Fungal Lung Diseases (ISS)

	Graves' disease (ISS)
	Hereditary Neoplastic Syndromes (ISS)
	Human Influenza (ISS)
	Hyperalgesia (ISS)
	Hyperplasia (ISS)
	Immediate Hypersensitivity (ISS)
	Inflammation (ISS)
	invasive ductal carcinoma (ISS)
	Kawasaki disease (ISS)
	lipoid nephrosis (ISS)
	localized scleroderma (ISS)
	lung disease (ISS)
	Lymphatic Metastasis (ISS)
	mastocytosis (ISS)
	Metaplasia (ISS)
	middle cerebral artery infarction (ISS)
	milk allergy (ISS)
	multiple sclerosis (ISS)
	Mycoplasma pneumoniae pneumonia (ISS)
	Nasal Polyps (ISS)
	nonalcoholic fatty liver disease (ISS)
	occupational dermatitis (ISS)
	onchocerciasis (ISS)
	ovarian carcinoma (ISS)
	pancreatic cancer (ISS)
	pancreatitis (ISS)
	peanut allergy (ISS)
	peptic esophagitis (ISS)
	Perennial Allergic Rhinitis (ISS)
	Picornaviridae Infections (ISS)
	Plasmodium falciparum malaria (ISS)
	pneumonia (ISS)

	prostatic hypertrophy (ISS)
	Pseudomonas Infections (ISS)
	psoriasis (ISS)
	psoriatic arthritis (ISS)
	pulmonary edema (ISS)
	pulmonary emphysema (ISS)
	pulmonary eosinophilia (ISS)
	pulmonary fibrosis (ISS)
	pulmonary hypertension (ISS)
	pulmonary tuberculosis (ISS)
	purpura (ISS)
	Radiation Pneumonitis (ISS)
	renal cell carcinoma (ISS)
	Reperfusion Injury (ISS)
	respiratory allergy (ISS)
	Respiratory Sounds (ISS)
	respiratory syncytial virus infectious disease (ISS)
	Respiratory Tract Granuloma (ISS)
	Respiratory Tract Infections (ISS)
	rheumatoid arthritis (ISS)
	rhinitis (ISS)
	Schistosomiasis Mansoni (ISS)
	Sepsis (ISS)
	sinusitis (ISS)
	Sjogren's syndrome (ISS)
	systemic lupus erythematosus (ISS)
	systemic scleroderma (ISS)
	T-Cell Lymphoma (ISS)
	Transplant Rejection (ISS)
	uveitis (ISS)
	vitiligo (ISS)

Gene Ontology Annotations

Biological Process

	cellular response to mechanical stimulus (ISS)
	cytokine-mediated signaling pathway (ISS)
	immune response (IEA,ISS)
	inflammatory response (ISS)
	microglial cell activation (ISS)
	negative regulation of complement-dependent cytotoxicity (ISS)
	negative regulation of endothelial cell apoptotic process (ISS)
	negative regulation of lung ciliated cell differentiation (ISS)
	negative regulation of NAD(P)H oxidase activity (ISS)
	negative regulation of neuron death (ISS)
	negative regulation of transforming growth factor beta production (ISS)
	positive regulation of B cell proliferation (ISS)
	positive regulation of cold-induced thermogenesis (ISS)
	positive regulation of connective tissue growth factor production (ISS)
	positive regulation of gene expression (ISS)

	positive regulation of immunoglobulin production (ISS)
	positive regulation of lung goblet cell differentiation (ISS)
	positive regulation of macrophage activation (ISS)
	positive regulation of mast cell degranulation (ISS)
	positive regulation of pancreatic stellate cell proliferation (ISS)
	positive regulation of protein secretion (ISS)
	positive regulation of release of sequestered calcium ion into cytosol (ISS)
	positive regulation of smooth muscle cell proliferation (ISS)
	positive regulation of tyrosine phosphorylation of STAT protein (ISS)
	regulation of proton transport (ISS)
	response to ethanol (ISS)
	response to lipopolysaccharide (ISS)
	response to nicotine (ISS)
	signal transduction (IEA)

Cellular Component

	cytoplasm (ISS)
	external side of plasma membrane (ISS)

	extracellular region (ISS)
	extracellular space (IEA,ISS)

Molecular Function

	cytokine activity (IEA,ISS)
	cytokine receptor binding (IEA,ISS)

	interleukin-13 receptor binding (ISS)
	protein binding (ISS)

Molecular Pathway Annotations

	asthma pathway (ISS)
	Fc epsilon receptor mediated signaling pathway (ISS)
	Jak-Stat signaling pathway (ISS)

measles pathway (ISS)

References - uncurated

PubMed

11032397

Genomics

Comparative Map Data

IL13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,957,870 - 20,961,391 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog Cytomap	11		NCBI

IL13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	132,656,524 - 132,661,109 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	5	131,993,865 - 131,996,801 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	132,021,764 - 132,024,700 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	5	132,021,763 - 132,024,700	NCBI
Celera	5	128,123,995 - 128,126,931 (+)	NCBI
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	127,186,169 - 127,189,105 (+)	NCBI		HuRef
CHM1_1	5	131,427,162 - 131,430,098 (+)	NCBI		CHM1_1

Il13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm38	11	53,631,323 - 53,634,702 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
MGSCv37	11	53,444,825 - 53,448,204 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	53,474,747 - 53,478,125 (-)	NCBI			mm8
Celera	11	58,210,849 - 58,214,228 (-)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	31.98	NCBI

Il13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	10	38,982,909 - 38,985,466 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	38,764,639 - 38,767,196 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	39,093,512 - 39,096,069 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	39,102,758 - 39,105,316 (-)	NCBI
Celera	10	37,134,342 - 37,136,897 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Il13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955408	4,046,406 - 4,049,795 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	134,235,788 - 134,240,548 (+)	NCBI	panpan1.1	PanPan1.1
Bonobo Cytomap	5		NCBI

Il13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936647	2,529,933 - 2,532,503 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	2	140,441,025 - 140,444,068 (+)	NCBI	Sscrofa10.2		susScr3
Sscrofa11.1	2	134,972,099 - 134,976,672 (+)	NCBI	Sscrofa11.1		susScr11	Sscrofa11.1
Pig Cytomap	2		NCBI

Sequence

Nucleotide Sequences

RefSeq Transcripts	NM_001003384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022424906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022424907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX03007772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF244915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_001003384 ⟹ NP_001003384

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,958,464 - 20,961,391 (+)	NCBI

Sequence:

show sequence

CTACGACCTGCCTGCTCTTCCCTCGCTCCTCCTGCATTGGCTCTGGGCTCCATGGCGCTCTGGT
TGACTGTGGTCATTGCTCTCACCTGCCTCGGTGGCCTTGCCTCCCCGAGCCCTGTGACTCCCTC
CCCAACCCTCAAGGAGCTCATTGAGGAGCTGGTCAACATCACCCAGAATCAGGCATCCCTCTGC
AACGGCAGCATGGTGTGGAGCGTCAACCTGACCGCCGGCATGTACTGCGCAGCTCTAGAATCTC
TGATCAATGTCTCCGACTGCAGCGCCATCCAAAGGACCCAGAGGATGCTGAAAGCACTGTGCTC
TCAAAAGCCCGCGGCAGGGCAGATTTCCAGTGAACGCAGCCGAGACACCAAAATTGAAGTGATC
CAGTTGGTGAAAAACCTGCTCACCTATGTAAGGGGAGTTTATCGCCATGGAAATTTCAGATGAA
GCATGAAAACTTAGCATCCTTATCTGTAGACCCAGACCTGACCACTTAAGTTCCAGATTCATTT
TTCTTTCCGACGTCACAAATTTCTTAGGGAGGTGGGGGGGGGGGAGAACCATTTCCTCAGCTGG
GACCTCAGCCTGCACCGCCTGCCTCCATGGAGCTGAGCCCAGCCACCCCTGCCTTGGTGCATGG
GGCCCAGCCGGGTGGCCCTCCTCCGTCTGCACTTCATCAACGCTGAGGGAAAGCACTGCATCCC
ATGACTGTCCCCTCCTCAGAGCAAAGTGCAGCATTACAGTGGAGGCAGATATGTGTGGGAGGGG
GTCTTGCTGTACCTGGGAGTGGCACAGACATGTTTCTTCTTAGCCTTATTTATTATTGTGTGTT
ATTTAAACAAGTGTCTTTGTTTGTGCTGGGGACAGGGAGTGGCTTGGAGCTGGGGGCCCAGTGA
CTCGGGTTTAGAGAGTCCCTGGGAATAAGCACTGTGTGTAAAATTCTGCTACCTCACTGGGATC
CTGGGGCCGACACAGGGGACAGGAGAAAGGGTCAGAGATGCTGCTCTTGTCTGCCACTCAGCAG
CTGGCCCTCAGCCAAGCAGTAATTTATTGTTTTTCCTTGTATTTAAAGTTAAGAAATAAAATAT
GTTATCAAAGAGTTAATAATATATAGAAGAGTAGCCTAAAAGGCTGCATTTGGTGTGTGTGGCC
AGGCCGGGGCGGGTGGGGGGGAGGGTGTTGTCACTGAATGTGCTCTTTCACTGACTTTGTCAAA
CTGGAAGCCAGAAATAAAGATGGTGACAAGAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_022424906 ⟹ XP_022280614

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,957,870 - 20,961,295 (+)	NCBI

Sequence:

show sequence

GGCAGGCTCCCTGCAGGGAGCCCGATGTGGGACTTGATCCCAGGACCCCGGGATCAGGACCTGA
GCCAAAGGCAGGCACTCAACCACTGAGCCACCCAGGTGTCCCCTTTTTATCCTGTTTGAGTTTG
TATCCAAATCAAGTATTAGAGACCGGTTCATTGAAAAAATAAAACCCCGAAATTCCCACATCTG
GTAGACTGTAGTCAGAGCATGGTTTGCTGAGAGCCTCTGGTGACCCAAAACAGTCTGTGGACAG
GGCTGGGCACTCAAGGTGGTTACCAATCAAAATTGCTGCAGTTCCGGCTGGCTTGGCTGACATC
AGGCTGCACTCAGGGCTCTCTTACCTACTCCTGGAGCAAGCCCATCCATATCTTGGAAAGCGCT
CCAGACCCCTCTCAATGATAAGTCCACAAGAAATCAAACTCTTTCCTTTATGCGACGCTGGATT
TTCCACAAAGTAAAATCAAGATGAGTAAAGATGTGGTTTCTAGATAGTACCCGACAAAGCGGAG
ACCAGGGTGGGAGGCGTCATCATTTGGCCTATAAAAGCTGCCACAAGAGGCCAAGGCCACAAGC
CACTCAGCTTAGGCCAGCCTACGACCTGCCTGCTCTTCCCTCGCTCCTCCTGCATTGGCTCTGG
GCTCCATGGCGCTCTGGTTGACTGTGGTCATTGCTCTCACCTGCCTCGGTGGCCTTGCCTCCCC
GAGCCCTGTGACTCCCTCCCCAACCCTCAAGGAGCTCATTGAGGAGCTGGTCAACATCACCCAG
AATCAGGCATCCCTCTGCAACGGCAGCATGGTGTGGAGCGTCAACCTGACCGCCGGCATGTACT
GCGCAGCTCTAGAATCTCTGATCAATGTCTCCGACTGCAGCGCCATCCAAAGGACCCAGAGGAT
GCTGAAAGCACTGTGCTCTCAAAAGCCCGCGGCAGGGATTTCCAGTGAACGCAGCCGAGACACC
AAAATTGAAGTGATCCAGTTGGTGAAAAACCTGCTCACCTATGTAAGGGGAGTTTATCGCCATG
GAAATTTCAGATGAAGCATGAAAACTTAGCATCCTTATCTGTAGACCCAGACCTGACCACTTAA
GTTCCAGATTCATTTTTCTTTCCGACGTCACAAATTTCTTAGGGGGGGGGGGGGAAGAACCATT
TCCTCAGCTGGGACCTCAGCCTGCACCGCCTGCCTCCATGGAGCTGAGCCCAGCCACCCCTGCC
TTGGTGCATGGGGCCCAGCCGGGTGGCCCTCCTCCGTCTGCACTTCATCAACGCTGAGGGAAAG
CACTGCATCCCATGACTGTCCCCTCCTCAGAGCAAAGTGCAGCATTACAGTGGAGGCAGATATG
TGTGGGAGGGGGTCTTGCTGTACCTGGGAGTGGCACAGACATGTTTCTTCTTAGCCTTATTTAT
TATTGTGTGTTATTTAAACAAGTGTGTTTGTTTGTGCTGGGGACAGGGAGTGGCTTGGAGCTGG
GGGCCCAGTGACTCGGGTTTAGAGAGTCCCTGGGAATAAGCACTGTGTGTAAAATTCTGCTACC
TCACTGGGATCCTGGGGCCGACACAGGGGACAGGAGAAAGGGTCAGAGATGCTGCTCTTGTCTG
CCACTCAGCAGCTGGCCCTCAGCCAAGCAGTAATTTATTGTTTTTCCTTGTATTTAAAGTTAAG
AAATAAAATATGTTATCAAAGAGTTAATAATATATAGAAGAGTAGCCTAAAAGGCTGCATTTGG
TGTGTGTGGCCA

hide sequence

RefSeq Acc Id:

XM_022424907 ⟹ XP_022280615

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,957,870 - 20,961,295 (+)	NCBI

Sequence:

show sequence

GGCAGGCTCCCTGCAGGGAGCCCGATGTGGGACTTGATCCCAGGACCCCGGGATCAGGACCTGA
GCCAAAGGCAGGCACTCAACCACTGAGCCACCCAGGTGTCCCCTTTTTATCCTGTTTGAGTTTG
TATCCAAATCAAGTATTAGAGACCGGTTCATTGAAAAAATAAAACCCCGAAATTCCCACATCTG
GTAGACTGTAGTCAGAGCATGGTTTGCTGAGAGCCTCTGGTGACCCAAAACAGTCTGTGGACAG
GGCTGGGCACTCAAGGTGGTTACCAATCAAAATTGCTGCAGTTCCGGCTGGCTTGGCTGACATC
AGGCTGCACTCAGGGCTCTCTTACCTACTCCTGGAGCAAGCCCATCCATATCTTGGAAAGCGCT
CCAGACCCCTCTCAATGATAAGTCCACAAGAAATCAAACTCTTTCCTTTATGCGACGCTGGATT
TTCCACAAAGTAAAATCAAGATGAGTAAAGATGTGGTTTCTAGATAGTACCCGACAAAGCGGAG
ACCAGGGTGGGAGGCGTCATCATTTGGCCTATAAAAGCTGCCACAAGAGGCCAAGGCCACAAGC
CACTCAGCTTAGGCCAGCCTACGACCTGCCTGCTCTTCCCTCGCTCCTCCTGCATTGGCTCTGG
GCTCCATGGCGCTCTGGTTGACTGTGGTCATTGCTCTCACCTGCCTCGGTGGCCTTGCCTCCCC
GAGCCCTGTGACTCCCTCCCCAACCCTCAAGGAGCTCATTGAGGAGCTGGTCAACATCACCCAG
AATCAGTACTGCGCAGCTCTAGAATCTCTGATCAATGTCTCCGACTGCAGCGCCATCCAAAGGA
CCCAGAGGATGCTGAAAGCACTGTGCTCTCAAAAGCCCGCGGCAGGGCAGATTTCCAGTGAACG
CAGCCGAGACACCAAAATTGAAGTGATCCAGTTGGTGAAAAACCTGCTCACCTATGTAAGGGGA
GTTTATCGCCATGGAAATTTCAGATGAAGCATGAAAACTTAGCATCCTTATCTGTAGACCCAGA
CCTGACCACTTAAGTTCCAGATTCATTTTTCTTTCCGACGTCACAAATTTCTTAGGGGGGGGGG
GGGAAGAACCATTTCCTCAGCTGGGACCTCAGCCTGCACCGCCTGCCTCCATGGAGCTGAGCCC
AGCCACCCCTGCCTTGGTGCATGGGGCCCAGCCGGGTGGCCCTCCTCCGTCTGCACTTCATCAA
CGCTGAGGGAAAGCACTGCATCCCATGACTGTCCCCTCCTCAGAGCAAAGTGCAGCATTACAGT
GGAGGCAGATATGTGTGGGAGGGGGTCTTGCTGTACCTGGGAGTGGCACAGACATGTTTCTTCT
TAGCCTTATTTATTATTGTGTGTTATTTAAACAAGTGTGTTTGTTTGTGCTGGGGACAGGGAGT
GGCTTGGAGCTGGGGGCCCAGTGACTCGGGTTTAGAGAGTCCCTGGGAATAAGCACTGTGTGTA
AAATTCTGCTACCTCACTGGGATCCTGGGGCCGACACAGGGGACAGGAGAAAGGGTCAGAGATG
CTGCTCTTGTCTGCCACTCAGCAGCTGGCCCTCAGCCAAGCAGTAATTTATTGTTTTTCCTTGT
ATTTAAAGTTAAGAAATAAAATATGTTATCAAAGAGTTAATAATATATAGAAGAGTAGCCTAAA
AGGCTGCATTTGGTGTGTGTGGCCA

hide sequence

Protein Sequences

Protein RefSeqs	NP_001003384	(Get FASTA)	NCBI Sequence Viewer
	XP_022280614	(Get FASTA)	NCBI Sequence Viewer
	XP_022280615	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF63204	(Get FASTA)	NCBI Sequence Viewer
	Q9N0W9	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001003384 ⟸ NM_001003384
- Peptide Label:	precursor
- UniProtKB:	Q9N0W9 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALWLTVVIALTCLGGLASPSPVTPSPTLKELIEELVNITQNQASLCNGSMVWSVNLTAGMYCA ALESLINVSDCSAIQRTQRMLKALCSQKPAAGQISSERSRDTKIEVIQLVKNLLTYVRGVYRHG NFR hide sequence

RefSeq Acc Id:	XP_022280614 ⟸ XM_022424906
- Peptide Label:	isoform X1
- Sequence:	show sequence MALWLTVVIALTCLGGLASPSPVTPSPTLKELIEELVNITQNQASLCNGSMVWSVNLTAGMYCA ALESLINVSDCSAIQRTQRMLKALCSQKPAAGISSERSRDTKIEVIQLVKNLLTYVRGVYRHGN FR hide sequence

RefSeq Acc Id:	XP_022280615 ⟸ XM_022424907
- Peptide Label:	isoform X2
- Sequence:	show sequence MALWLTVVIALTCLGGLASPSPVTPSPTLKELIEELVNITQNQYCAALESLINVSDCSAIQRTQ RMLKALCSQKPAAGQISSERSRDTKIEVIQLVKNLLTYVRGVYRHGNFR hide sequence

Promoters

RGD ID:

13685171

Promoter ID:

EPDNEW_C3239

Type:

single initiation site

Name:

IL13_1

Description:

interleukin 13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	20,958,442 - 20,958,502	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000000878	ENTREZGENE
Ensembl Protein	ENSCAFP00000001250	ENTREZGENE
Ensembl Transcript	ENSCAFT00000001364	ENTREZGENE
InterPro	4_helix_cytokine-like_core	UniProtKB/Swiss-Prot
	IL-13	UniProtKB/Swiss-Prot
	IL-4/IL-13	UniProtKB/Swiss-Prot
	IL-4/IL-13_CS	UniProtKB/Swiss-Prot
KEGG Report	cfa:442990	UniProtKB/Swiss-Prot
NCBI Gene	IL13	ENTREZGENE
Pfam	IL13	UniProtKB/Swiss-Prot
PRINTS	INTRLEUKIN13	UniProtKB/Swiss-Prot
PROSITE	INTERLEUKIN_4_13	UniProtKB/Swiss-Prot
SMART	IL4_13	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47266	UniProtKB/Swiss-Prot
UniGene	Cfa.3566	ENTREZGENE
UniProt	IL13_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE

More on IL13
	NCBI Gene
	Ensembl Gene
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	12404079
Created:	2017-01-24
Species:	Canis lupus familiaris
Last Modified:	2019-05-14
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.