MAD2L1BP (MAD2L1 binding protein) - Rat Genome Database

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Gene: MAD2L1BP (MAD2L1 binding protein) Canis lupus familiaris
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Symbol: MAD2L1BP
Name: MAD2L1 binding protein
RGD ID: 12402783
Description: INVOLVED IN axoneme assembly (inferred); cell projection organization (inferred); cilium movement involved in cell motility (inferred); ASSOCIATED WITH genetic disease (ortholog); infantile Refsum disease (ortholog); Zellweger syndrome (ortholog); FOUND IN axoneme (inferred); cell projection (inferred); cilium (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MAD2L1-binding protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,085,825 - 12,089,907 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,085,915 - 12,090,411 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,112,275 - 12,117,289 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,569,776 - 12,574,790 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,569,868 - 12,574,332 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,094,863 - 12,099,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,181,890 - 12,186,897 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,275,386 - 12,280,401 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MAD2L1BP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,085,825 - 12,089,907 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,085,915 - 12,090,411 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,112,275 - 12,117,289 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,569,776 - 12,574,790 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,569,868 - 12,574,332 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,094,863 - 12,099,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,181,890 - 12,186,897 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,275,386 - 12,280,401 (+)NCBIUU_Cfam_GSD_1.0
MAD2L1BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,629,540 - 43,640,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,629,540 - 43,640,941 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,597,277 - 43,608,678 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,705,257 - 43,716,667 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,711,554 - 43,716,664NCBI
Celera645,148,900 - 45,160,310 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,316,454 - 43,327,864 (+)NCBIHuRef
CHM1_1643,600,342 - 43,611,752 (+)NCBICHM1_1
T2T-CHM13v2.0643,458,178 - 43,469,674 (+)NCBIT2T-CHM13v2.0
Mad2l1bp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,458,311 - 46,464,477 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,458,313 - 46,464,479 (-)EnsemblGRCm39 Ensembl
GRCm381746,147,385 - 46,153,551 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,147,387 - 46,153,553 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,284,334 - 46,290,500 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,610,970 - 45,617,117 (-)NCBIMGSCv36mm8
Celera1749,578,789 - 49,584,951 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.88NCBI
Mad2l1bp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,329,699 - 22,334,024 (+)NCBIGRCr8
mRatBN7.2914,832,133 - 14,836,458 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,832,132 - 14,837,447 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,416,692 - 23,421,036 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0928,479,122 - 28,483,457 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,780,120 - 26,784,464 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,217,141 - 17,221,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,216,495 - 17,221,434 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,112,968 - 16,117,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,396,316 - 10,401,505 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,393,637 - 10,398,824 (+)NCBI
Celera912,579,446 - 12,583,626 (+)NCBICelera
Cytogenetic Map9q12NCBI
Mad2l1bp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554379,423,630 - 9,433,357 (+)NCBIChiLan1.0ChiLan1.0
MAD2L1BP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,133,961 - 58,139,117 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,003,743 - 54,008,898 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,219,638 - 43,230,988 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,515,529 - 44,520,288 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,509,839 - 44,521,590 (+)Ensemblpanpan1.1panPan2
Mad2l1bp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,574,303 - 47,580,270 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,380,356 - 16,385,479 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,379,932 - 16,385,812 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAD2L1BP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,613,440 - 38,623,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,613,349 - 38,623,845 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2744,195,882 - 44,206,358 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAD2L1BP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,524,122 - 28,529,162 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1728,524,117 - 28,529,139 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,688,591 - 43,693,762 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mad2l1bp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,045,331 - 16,047,497 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,044,275 - 16,047,500 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MAD2L1BP
29 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 16 1 2 12 10 6
Low 3 5 6 6 5 6 4 6 8
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000003043   ⟹   ENSCAFP00000002825
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1212,085,915 - 12,090,411 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845018198   ⟹   ENSCAFP00845014188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1212,569,868 - 12,574,332 (+)Ensembl
RefSeq Acc Id: XM_038491917   ⟹   XP_038347845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11212,094,863 - 12,099,876 (+)NCBI
RefSeq Acc Id: XM_038554182   ⟹   XP_038410110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01212,275,386 - 12,280,401 (+)NCBI
RefSeq Acc Id: XM_038618047   ⟹   XP_038473975
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01212,181,890 - 12,186,897 (+)NCBI
RefSeq Acc Id: XM_038683643   ⟹   XP_038539571
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01212,569,776 - 12,574,790 (+)NCBI
RefSeq Acc Id: XM_532151   ⟹   XP_532151
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11212,085,825 - 12,089,907 (+)NCBI
Dog10K_Boxer_Tasha1212,112,275 - 12,117,289 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532151   ⟸   XM_532151
- UniProtKB: A0A8C0RH33 (UniProtKB/TrEMBL),   A0A8C0KG36 (UniProtKB/TrEMBL),   A0A8I3RXU8 (UniProtKB/TrEMBL),   A0A8C0MTT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000002825   ⟸   ENSCAFT00000003043
RefSeq Acc Id: XP_038347845   ⟸   XM_038491917
RefSeq Acc Id: XP_038473975   ⟸   XM_038618047
RefSeq Acc Id: XP_038539571   ⟸   XM_038683643
- UniProtKB: A0A8C0RH33 (UniProtKB/TrEMBL),   A0A8C0KG36 (UniProtKB/TrEMBL),   A0A8I3RXU8 (UniProtKB/TrEMBL),   A0A8C0MTT6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410110   ⟸   XM_038554182
- UniProtKB: A0A8C0KG36 (UniProtKB/TrEMBL),   A0A8C0MTT6 (UniProtKB/TrEMBL),   A0A8C0RH33 (UniProtKB/TrEMBL),   A0A8I3RXU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845014188   ⟸   ENSCAFT00845018198

Promoters
RGD ID:13685441
Promoter ID:EPDNEW_C3509
Type:initiation region
Name:MAD2L1BP_1
Description:MAD2L1 binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11212,085,901 - 12,085,961EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001922 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010309 UniProtKB/TrEMBL
  ENSCAFG00040009020 UniProtKB/TrEMBL
  ENSCAFG00845010340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003043.5 UniProtKB/TrEMBL
  ENSCAFT00030019028.1 UniProtKB/TrEMBL
  ENSCAFT00030019121.1 UniProtKB/TrEMBL
  ENSCAFT00030019164.1 UniProtKB/TrEMBL
  ENSCAFT00040016742.1 UniProtKB/TrEMBL
  ENSCAFT00845018198 ENTREZGENE
  ENSCAFT00845018198.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.900.20 UniProtKB/TrEMBL
InterPro MAD1/Cdc20-bound-Mad2-bd UniProtKB/TrEMBL
KEGG Report cfa:474916 UniProtKB/TrEMBL
NCBI Gene MAD2L1BP ENTREZGENE
PANTHER MAD2L1-BINDING PROTEIN UniProtKB/TrEMBL
  MITOCHONDRIAL RIBOSOMAL PROTEIN S18 UniProtKB/TrEMBL
  PTHR15681 UniProtKB/TrEMBL
  RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG UniProtKB/TrEMBL
Pfam p31comet UniProtKB/TrEMBL
UniProt A0A8C0KG36 ENTREZGENE
  A0A8C0MTT6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MY09_CANLF UniProtKB/TrEMBL
  A0A8C0RH33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RXU8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42915 ENTREZGENE