TMEM17 (transmembrane protein 17) - Rat Genome Database

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Gene: TMEM17 (transmembrane protein 17) Canis lupus familiaris
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Symbol: TMEM17
Name: transmembrane protein 17
RGD ID: 12402775
Description: INVOLVED IN smoothened signaling pathway (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); Joubert syndrome 1 (ortholog); FOUND IN cell projection (inferred); ciliary membrane (inferred); ciliary transition zone (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11062,355,849 - 62,361,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1062,356,277 - 62,361,397 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1062,243,628 - 62,249,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01063,363,234 - 63,368,846 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1063,363,662 - 63,368,797 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11063,046,203 - 63,051,806 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01063,349,705 - 63,355,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,646,177 - 63,651,789 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TMEM17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11062,355,849 - 62,361,445 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1062,356,277 - 62,361,397 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1062,243,628 - 62,249,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01063,363,234 - 63,368,846 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1063,363,662 - 63,368,797 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11063,046,203 - 63,051,806 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01063,349,705 - 63,355,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,646,177 - 63,651,789 (-)NCBIUU_Cfam_GSD_1.0
TMEM17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38262,453,531 - 62,506,195 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl262,500,218 - 62,511,894 (-)EnsemblGRCh38hg38GRCh38
GRCh37262,727,353 - 62,733,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36262,581,252 - 62,586,980 (-)NCBINCBI36Build 36hg18NCBI36
Build 34262,639,412 - 62,645,127NCBI
Celera262,572,191 - 62,578,440 (-)NCBICelera
Cytogenetic Map2p15NCBI
HuRef262,465,324 - 62,471,573 (-)NCBIHuRef
CHM1_1262,657,923 - 62,664,172 (-)NCBICHM1_1
T2T-CHM13v2.0262,459,855 - 62,512,518 (-)NCBIT2T-CHM13v2.0
Tmem17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391122,462,283 - 22,469,231 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1122,462,088 - 22,469,234 (+)EnsemblGRCm39 Ensembl
GRCm381122,512,283 - 22,519,231 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1122,512,088 - 22,519,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv371122,412,286 - 22,419,234 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,412,286 - 22,419,234 (+)NCBIMGSCv36mm8
Celera1124,649,073 - 24,656,059 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.17NCBI
Tmem17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814100,684,655 - 100,725,471 (+)NCBIGRCr8
mRatBN7.21496,483,648 - 96,524,238 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1496,518,793 - 96,524,233 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14100,863,078 - 100,869,002 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014102,105,343 - 102,111,268 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01498,576,957 - 98,582,881 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014107,268,235 - 107,308,546 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14107,268,128 - 107,308,542 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014107,331,758 - 107,371,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414103,162,310 - 103,167,728 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114103,181,520 - 103,186,939 (+)NCBI
Celera1495,508,270 - 95,513,688 (+)NCBICelera
Cytogenetic Map14q22NCBI
Tmem17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542421,627,151 - 21,637,041 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542421,627,889 - 21,634,798 (+)NCBIChiLan1.0ChiLan1.0
TMEM17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21263,877,577 - 63,886,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A63,881,521 - 63,890,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A62,580,872 - 62,587,936 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A63,710,004 - 63,716,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A63,710,004 - 63,716,422 (-)Ensemblpanpan1.1panPan2
Tmem17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629220,844,325 - 20,850,142 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364917,719,658 - 7,727,107 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364917,721,150 - 7,726,983 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,415,717 - 79,422,393 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1379,415,767 - 79,422,397 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMEM17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11444,462,402 - 44,468,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1444,462,158 - 44,468,975 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604567,365,751 - 67,371,995 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476210,969,765 - 10,976,870 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476210,970,048 - 10,975,736 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM17
63 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 17 1 1 1 12 5 5
Low 5 5 5 5 6 5 5 6 8 5 1
Below cutoff

Sequence


RefSeq Acc Id: ENSCAFT00000004992   ⟹   ENSCAFP00000004629
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1062,356,277 - 62,361,397 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845029671   ⟹   ENSCAFP00845023305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1063,363,662 - 63,368,797 (-)Ensembl
RefSeq Acc Id: XM_038489418   ⟹   XP_038345346
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11063,046,203 - 63,051,806 (-)NCBI
RefSeq Acc Id: XM_038551400   ⟹   XP_038407328
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01063,646,177 - 63,651,789 (-)NCBI
RefSeq Acc Id: XM_038615335   ⟹   XP_038471263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01063,349,705 - 63,355,323 (-)NCBI
RefSeq Acc Id: XM_038680723   ⟹   XP_038536651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01063,363,234 - 63,368,846 (-)NCBI
RefSeq Acc Id: XM_531842   ⟹   XP_531842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11062,355,849 - 62,361,445 (-)NCBI
Dog10K_Boxer_Tasha1062,243,628 - 62,249,224 (-)NCBI
Sequence:
RefSeq Acc Id: XP_531842   ⟸   XM_531842
- UniProtKB: A0A8P0S8U9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000004629   ⟸   ENSCAFT00000004992
RefSeq Acc Id: XP_038345346   ⟸   XM_038489418
RefSeq Acc Id: XP_038471263   ⟸   XM_038615335
RefSeq Acc Id: XP_038536651   ⟸   XM_038680723
- UniProtKB: A0A8C0Q6Y9 (UniProtKB/TrEMBL),   A0A8C0R8Q0 (UniProtKB/TrEMBL),   A0A8I3P2T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407328   ⟸   XM_038551400
- UniProtKB: A0A8C0Q6Y9 (UniProtKB/TrEMBL),   A0A8C0R8Q0 (UniProtKB/TrEMBL),   A0A8I3P2T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845023305   ⟸   ENSCAFT00845029671

Promoters
RGD ID:13685082
Promoter ID:EPDNEW_C3150
Type:multiple initiation site
Name:TMEM17_1
Description:transmembrane protein 17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11062,361,404 - 62,361,464EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003110 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018978 UniProtKB/TrEMBL
  ENSCAFG00040004004 UniProtKB/TrEMBL
  ENSCAFG00845016745 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000004992.5 UniProtKB/TrEMBL
  ENSCAFT00030034872.1 UniProtKB/TrEMBL
  ENSCAFT00040007657.1 UniProtKB/TrEMBL
  ENSCAFT00845029671 ENTREZGENE
  ENSCAFT00845029671.1 UniProtKB/TrEMBL
InterPro Uncharacterised_TM-17 UniProtKB/TrEMBL
KEGG Report cfa:474612 UniProtKB/TrEMBL
NCBI Gene TMEM17 ENTREZGENE
PANTHER PTHR13531 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 17 UniProtKB/TrEMBL
Pfam Transmemb_17 UniProtKB/TrEMBL
UniProt A0A8C0Q6Y9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R8Q0 ENTREZGENE
  A0A8I3P2T5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0S8U9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47496 ENTREZGENE