MIR128-1 (microRNA mir-128-1) - Rat Genome Database

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Gene: MIR128-1 (microRNA mir-128-1) Canis lupus familiaris
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Symbol: MIR128-1
Name: microRNA mir-128-1
RGD ID: 12400561
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-128-1; microRNA 128-1
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,435,956 - 38,436,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,679,708 - 38,679,763 (+)NCBI
ROS_Cfam_1.01939,881,919 - 39,881,974 (+)NCBI
UMICH_Zoey_3.11938,524,004 - 38,524,059 (+)NCBI
UNSW_CanFamBas_1.01938,687,099 - 38,687,154 (+)NCBI
UU_Cfam_GSD_1.01939,920,158 - 39,920,213 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR128-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11938,435,956 - 38,436,011 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1938,679,708 - 38,679,763 (+)NCBI
ROS_Cfam_1.01939,881,919 - 39,881,974 (+)NCBI
UMICH_Zoey_3.11938,524,004 - 38,524,059 (+)NCBI
UNSW_CanFamBas_1.01938,687,099 - 38,687,154 (+)NCBI
UU_Cfam_GSD_1.01939,920,158 - 39,920,213 (+)NCBI
MIR128-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382135,665,397 - 135,665,478 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2135,665,397 - 135,665,478 (+)EnsemblGRCh38hg38GRCh38
GRCh372136,422,967 - 136,423,048 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,139,436 - 136,139,517 (+)NCBINCBI36hg18NCBI36
Celera2130,133,728 - 130,133,809 (+)NCBI
Cytogenetic Map2q21.3NCBI
HuRef2128,415,938 - 128,416,019 (+)NCBIHuRef
CHM1_12136,427,877 - 136,427,958 (+)NCBICHM1_1
T2T-CHM13v2.02136,105,929 - 136,106,010 (+)NCBI
Mir128-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391128,130,098 - 128,130,167 (+)NCBIGRCm39mm39
GRCm39 Ensembl1128,130,098 - 128,130,167 (+)Ensembl
GRCm381128,202,361 - 128,202,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1128,202,361 - 128,202,430 (+)EnsemblGRCm38mm10GRCm38
MGSCv371130,098,938 - 130,099,007 (+)NCBIGRCm37mm9NCBIm37
Celera1130,829,788 - 130,829,857 (+)NCBICelera
Cytogenetic Map1E3NCBI
Mir128-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21339,699,449 - 39,699,530 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1339,699,449 - 39,699,530 (+)Ensembl
Rnor_6.01344,916,534 - 44,916,615 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1344,916,534 - 44,916,615 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01350,001,706 - 50,001,787 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1340,073,464 - 40,073,545 (+)NCBICelera
Cytogenetic Map13q13NCBI
MIR128-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1516,273,551 - 16,273,659 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11516,273,557 - 16,273,638 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21518,661,614 - 18,661,695 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NR_049262
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11938,435,956 - 38,436,011 (+)NCBI
Dog10K_Boxer_Tasha1938,679,708 - 38,679,763 (+)NCBI
ROS_Cfam_1.01939,881,919 - 39,881,974 (+)NCBI
UMICH_Zoey_3.11938,524,004 - 38,524,059 (+)NCBI
UNSW_CanFamBas_1.01938,687,099 - 38,687,154 (+)NCBI
UU_Cfam_GSD_1.01939,920,158 - 39,920,213 (+)NCBI
Sequence:
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
19 38485149 38485150 T A snv Great Lakes Wolf (SRS661486)


Additional Information

Database Acc Id Source(s)
miRBase MI0008032 ENTREZGENE
NCBI Gene MIR128-1 ENTREZGENE
RNAcentral URS000024A59E RNACentral
  URS00007E36DB RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR128-1  microRNA mir-128-1    microRNA 128-1  Symbol and/or name change 5135510 APPROVED