DDX17 (DEAD-box helicase 17) - Rat Genome Database

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Gene: DDX17 (DEAD-box helicase 17) Canis lupus familiaris
Analyze
Symbol: DDX17
Name: DEAD-box helicase 17
RGD ID: 12399604
Description: ENCODES a protein that exhibits chromatin DNA binding (ortholog); lncRNA binding (ortholog); INVOLVED IN gene expression (ortholog); miRNA transcription (ortholog); myoblast differentiation (ortholog); ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); myoclonic dystonia 26 (ortholog); FOUND IN cytoplasm (inferred); nuclear speck (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DEAD (Asp-Glu-Ala-Asp) box polypeptide 17; probable ATP-dependent RNA helicase DDX17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,282,592 - 26,303,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,282,598 - 26,301,633 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,237,306 - 26,258,327 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,073,043 - 27,094,074 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,072,471 - 27,094,071 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,794,780 - 26,815,505 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,105,990 - 27,127,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,282,715 - 27,303,747 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DDX17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,282,592 - 26,303,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,282,598 - 26,301,633 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,237,306 - 26,258,327 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,073,043 - 27,094,074 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,072,471 - 27,094,071 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,794,780 - 26,815,505 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,105,990 - 27,127,019 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,282,715 - 27,303,747 (+)NCBIUU_Cfam_GSD_1.0
DDX17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,483,438 - 38,506,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,483,438 - 38,507,660 (-)EnsemblGRCh38hg38GRCh38
GRCh372238,879,443 - 38,902,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,209,389 - 37,232,291 (-)NCBINCBI36Build 36hg18NCBI36
Build 342237,203,942 - 37,209,466NCBI
Celera2222,685,022 - 22,707,930 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,845,483 - 21,868,386 (-)NCBIHuRef
CHM1_12238,838,236 - 38,861,132 (-)NCBICHM1_1
T2T-CHM13v2.02238,947,707 - 38,970,570 (-)NCBIT2T-CHM13v2.0
Ddx17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,411,897 - 79,430,976 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,411,937 - 79,430,942 (-)EnsemblGRCm39 Ensembl
GRCm381579,527,696 - 79,546,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,527,736 - 79,546,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv371579,358,126 - 79,377,171 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,354,991 - 79,373,814 (-)NCBIMGSCv36mm8
Celera1581,652,214 - 81,671,297 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.77NCBI
Ddx17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,971,522 - 112,989,747 (-)NCBIGRCr8
mRatBN7.27111,091,127 - 111,109,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,089,445 - 111,109,193 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,838,716 - 112,856,990 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,062,251 - 115,080,524 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,031,624 - 115,049,898 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,761,843 - 120,765,012 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,761,826 - 120,780,641 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,754,842 - 120,758,011 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,552,040 - 117,554,887 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,570,607 - 117,591,584 (+)NCBI
Celera7107,422,522 - 107,425,390 (-)NCBICelera
Cytogenetic Map7q34NCBI
Ddx17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,646,320 - 24,664,614 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,646,317 - 24,664,614 (-)NCBIChiLan1.0ChiLan1.0
DDX17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,339,405 - 48,363,355 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,030,869 - 51,055,784 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,398,801 - 19,421,587 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,218,884 - 37,241,430 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,218,884 - 37,241,425 (-)Ensemblpanpan1.1panPan2
Ddx17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,796,194 - 9,815,657 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,806,516 - 2,827,181 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,806,630 - 2,826,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,485,702 - 9,505,157 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,485,792 - 9,505,157 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,766,508 - 6,783,741 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,145,576 - 21,167,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,145,417 - 21,167,543 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,598,872 - 104,623,267 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,602,447 - 9,620,575 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,602,267 - 9,620,770 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DDX17
177 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000002162   ⟹   ENSCAFP00000002001
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1026,282,598 - 26,301,633 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000037931   ⟹   ENSCAFP00000033581
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1026,282,835 - 26,297,700 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845041851   ⟹   ENSCAFP00845032829
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,072,471 - 27,088,642 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845041974   ⟹   ENSCAFP00845032920
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,073,438 - 27,094,071 (+)Ensembl
RefSeq Acc Id: XM_022424303   ⟹   XP_022280011
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11026,282,592 - 26,303,128 (+)NCBI
Dog10K_Boxer_Tasha1026,237,306 - 26,258,327 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038489581   ⟹   XP_038345509
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11026,794,780 - 26,815,505 (+)NCBI
RefSeq Acc Id: XM_038551570   ⟹   XP_038407498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01027,282,715 - 27,303,747 (+)NCBI
RefSeq Acc Id: XM_038613517   ⟹   XP_038469445
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01027,105,990 - 27,127,019 (+)NCBI
RefSeq Acc Id: XM_038678884   ⟹   XP_038534812
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01027,073,043 - 27,094,074 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_022280011   ⟸   XM_022424303
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QAA0 (UniProtKB/TrEMBL),   A0A8I3S7P0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000033581   ⟸   ENSCAFT00000037931
RefSeq Acc Id: ENSCAFP00000002001   ⟸   ENSCAFT00000002162
RefSeq Acc Id: XP_038345509   ⟸   XM_038489581
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038469445   ⟸   XM_038613517
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038534812   ⟸   XM_038678884
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QAA0 (UniProtKB/TrEMBL),   A0A8I3S7P0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407498   ⟸   XM_038551570
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QAA0 (UniProtKB/TrEMBL),   A0A8I3S7P0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845032829   ⟸   ENSCAFT00845041851
RefSeq Acc Id: ENSCAFP00845032920   ⟸   ENSCAFT00845041974
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal

Promoters
RGD ID:13684970
Promoter ID:EPDNEW_C3038
Type:initiation region
Name:DDX17_1
Description:DEAD-box helicase 17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11026,282,524 - 26,282,584EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001395 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040007002 UniProtKB/TrEMBL
  ENSCAFG00845023692 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002162.7 UniProtKB/TrEMBL
  ENSCAFT00000037931.4 UniProtKB/TrEMBL
  ENSCAFT00040013062.1 UniProtKB/TrEMBL
  ENSCAFT00845041851.1 UniProtKB/TrEMBL
  ENSCAFT00845041974 ENTREZGENE
  ENSCAFT00845041974.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DDX17_ATP-bd-dom UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA-helicase_DEAD-box_CS UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
NCBI Gene DDX17 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DDX17-RELATED UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE DEAD_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0QAA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PJZ1_CANLF UniProtKB/TrEMBL
  A0A8I3S7P0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NME2_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39846 ENTREZGENE