SRP54 (signal recognition particle 54) - Rat Genome Database

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Gene: SRP54 (signal recognition particle 54) Canis lupus familiaris
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Symbol: SRP54
Name: signal recognition particle 54
RGD ID: 12398498
Description: ENCODES a protein that exhibits endoplasmic reticulum signal peptide binding; 7S RNA binding (ortholog); GDP binding (ortholog); INVOLVED IN protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; SRP-dependent cotranslational protein targeting to membrane, translocation; ASSOCIATED WITH genetic disease (ortholog); severe congenital neutropenia 8 (ortholog); Shwachman-Diamond syndrome (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: signal recognition particle 54 kDa protein; signal recognition particle 54kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,800,275 - 13,837,799 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha813,597,521 - 13,634,635 (+)NCBI
ROS_Cfam_1.0813,907,202 - 13,944,631 (+)NCBI
UMICH_Zoey_3.1813,608,264 - 13,646,077 (+)NCBI
UNSW_CanFamBas_1.0813,673,490 - 13,710,632 (+)NCBI
UU_Cfam_GSD_1.0813,962,922 - 13,999,855 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:2502717   PMID:8521805   PMID:16469117  


Genomics

Comparative Map Data
SRP54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,800,275 - 13,837,799 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha813,597,521 - 13,634,635 (+)NCBI
ROS_Cfam_1.0813,907,202 - 13,944,631 (+)NCBI
UMICH_Zoey_3.1813,608,264 - 13,646,077 (+)NCBI
UNSW_CanFamBas_1.0813,673,490 - 13,710,632 (+)NCBI
UU_Cfam_GSD_1.0813,962,922 - 13,999,855 (+)NCBI
SRP54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1434,981,957 - 35,029,686 (+)EnsemblGRCh38hg38GRCh38
GRCh381434,982,981 - 35,029,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371435,452,198 - 35,498,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,521,982 - 34,568,519 (+)NCBINCBI36hg18NCBI36
Build 341434,521,981 - 34,568,517NCBI
Celera1415,315,912 - 15,362,600 (+)NCBI
Cytogenetic Map14q13.2NCBI
HuRef1415,564,659 - 15,611,702 (+)NCBIHuRef
CHM1_11435,450,690 - 35,497,725 (+)NCBICHM1_1
Srp54a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,127,261 - 55,162,152 (+)NCBIGRCm39mm39
GRCm39 Ensembl1255,127,047 - 55,162,152 (+)Ensembl
GRCm381255,080,476 - 55,115,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,080,262 - 55,115,367 (+)EnsemblGRCm38mm10GRCm38
MGSCv371256,181,483 - 56,216,354 (+)NCBIGRCm37mm9NCBIm37
MGSCv361255,998,696 - 56,031,814 (+)NCBImm8
Celera1256,371,141 - 56,408,843 (+)NCBICelera
Cytogenetic Map12C1NCBI
Srp54a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2672,587,582 - 72,645,154 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl672,587,605 - 72,625,189 (+)Ensembl
Rnor_6.0675,996,629 - 76,035,768 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl675,996,643 - 76,034,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,532,350 - 85,572,100 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,446,838 - 75,494,001 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1675,474,626 - 75,478,796 (+)NCBI
Celera671,428,873 - 71,466,500 (+)NCBICelera
Cytogenetic Map6q23NCBI
Srp54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,977,226 - 26,016,351 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540925,977,226 - 26,016,351 (-)NCBIChiLan1.0ChiLan1.0
SRP54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11433,920,330 - 33,966,023 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1433,920,287 - 34,017,151 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01415,733,446 - 15,779,987 (+)NCBIMhudiblu_PPA_v0panPan3
LOC101965130
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,677,956 - 45,741,100 (+)NCBI
SpeTri2.0NW_0049364949,183,620 - 9,220,510 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRP54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,828,874 - 64,877,193 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1764,829,625 - 64,877,574 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,658,033 - 69,706,782 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRP54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12411,802,671 - 11,846,534 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2411,812,672 - 11,846,675 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666053764,178 - 808,147 (+)NCBIVero_WHO_p1.0
Srp54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248381,697,863 - 1,747,115 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 4 20 4 6 4 6 5 12 8 10 6
Low 1 2 2 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000021158   ⟹   ENSCAFP00000019649
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000061294   ⟹   ENSCAFP00000050551
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl813,677,760 - 13,837,722 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000076258   ⟹   ENSCAFP00000045385
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl813,809,946 - 13,837,722 (+)Ensembl
RefSeq Acc Id: NM_001003272   ⟹   NP_001003272
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1813,800,611 - 13,837,722 (+)NCBI
Dog10K_Boxer_Tasha813,597,521 - 13,634,635 (+)NCBI
ROS_Cfam_1.0813,907,511 - 13,944,624 (+)NCBI
UMICH_Zoey_3.1813,608,264 - 13,646,077 (+)NCBI
UNSW_CanFamBas_1.0813,673,490 - 13,710,632 (+)NCBI
UU_Cfam_GSD_1.0813,962,922 - 13,999,855 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038672855   ⟹   XP_038528783
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0813,907,202 - 13,944,631 (+)NCBI
RefSeq Acc Id: XM_038672856   ⟹   XP_038528784
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0813,914,525 - 13,944,631 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001003272 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528783 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528784 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA34385 (Get FASTA)   NCBI Sequence Viewer  
  P61010 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003272   ⟸   NM_001003272
- UniProtKB: P61010 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000019649   ⟸   ENSCAFT00000021158
RefSeq Acc Id: ENSCAFP00000045385   ⟸   ENSCAFT00000076258
RefSeq Acc Id: ENSCAFP00000050551   ⟸   ENSCAFT00000061294
RefSeq Acc Id: XP_038528783   ⟸   XM_038672855
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528784   ⟸   XM_038672856
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013331 Ensembl
NCBI Gene SRP54 ENTREZGENE
UniProt P61010 ENTREZGENE
VGNC ID VGNC:46807 ENTREZGENE