OR5T1 (olfactory receptor family 5 subfamily T member 1)

Gene: OR5T1 (olfactory receptor family 5 subfamily T member 1) Canis lupus familiaris

Analyze

Symbol:

OR5T1

Name:

olfactory receptor family 5 subfamily T member 1

RGD ID:

12397599

Description:

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC100685095; olfactory receptor 5T1; olfactory receptor 5T1-like

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	39,732,423 - 39,733,409 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	39,732,423 - 39,734,357 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	39,257,414 - 39,258,400 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	40,426,992 - 40,427,978 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	40,426,992 - 40,428,926 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	40,032,932 - 40,033,918 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	39,598,912 - 39,599,898 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	40,185,708 - 40,186,694 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

odorant binding (IEA)

olfactory receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

OR5T1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	39,732,423 - 39,733,409 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	39,732,423 - 39,734,357 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	39,257,414 - 39,258,400 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	40,426,992 - 40,427,978 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	40,426,992 - 40,428,926 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	40,032,932 - 40,033,918 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	39,598,912 - 39,599,898 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	40,185,708 - 40,186,694 (+)	NCBI		UU_Cfam_GSD_1.0

OR5T1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	56,274,154 - 56,276,819 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	56,274,154 - 56,276,819 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	56,041,630 - 56,044,295 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	55,799,691 - 55,800,671 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	55,799,690 - 55,800,671	NCBI
Celera	11	53,383,199 - 53,384,179 (+)	NCBI		Celera
Cytogenetic Map	11	q12.1	NCBI
HuRef	11	52,372,420 - 52,373,400 (+)	NCBI		HuRef
CHM1_1	11	55,909,307 - 55,910,287 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	56,212,049 - 56,214,714 (+)	NCBI		T2T-CHM13v2.0

Or5t5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	86,612,889 - 86,617,135 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	86,612,823 - 86,617,960 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	86,782,545 - 86,786,791 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	86,782,479 - 86,787,616 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	86,625,889 - 86,626,857 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	86,586,571 - 86,587,539 (+)	NCBI		MGSCv36	mm8
Celera	2	88,383,102 - 88,384,070 (+)	NCBI		Celera
Cytogenetic Map	2	D	NCBI
cM Map	2	49.86	NCBI

Or5t5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	92,209,945 - 92,210,913 (+)	NCBI		GRCr8
mRatBN7.2	3	71,839,853 - 71,840,821 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	71,835,920 - 71,842,062 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_WKY_Bbb_1.0	3	81,576,627 - 81,577,595 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	74,341,751 - 74,342,719 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	74,341,751 - 74,342,719 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	80,991,897 - 80,992,865 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	69,998,119 - 69,999,087 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	69,894,490 - 69,895,459 (+)	NCBI
Celera	3	71,105,315 - 71,106,283 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

LOC100974481
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	57,407,471 - 57,408,493 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	58,422,981 - 58,424,003 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	51,490,757 - 51,491,779 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

Variants

Variants in OR5T1
30 total Variants

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014120916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038425517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038501838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038564477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038628595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000039336 ⟹ ENSCAFP00000035172

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	39,732,423 - 39,734,357 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845011556 ⟹ ENSCAFP00845009028

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	40,426,992 - 40,428,926 (+)	Ensembl

RefSeq Acc Id:

XM_014120916 ⟹ XP_013976391

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	39,732,423 - 39,733,409 (+)	NCBI
Dog10K_Boxer_Tasha	18	39,257,414 - 39,258,400 (+)	NCBI

Sequence:

show sequence

ATGCCAGGATTTCCATCAGATTTAGATTTATACAGGATTCAGATGAAAAATGTGACTGAGGCCA
CCATGTTTATATTGATGGGCTTCACAGATGATTTTGAGATGCAGGTCTTCCTATTTTTACTATT
TCTAGCAATCTATCTTTTTACTCTGATAGGAAACTTGGGACTGGTTATATTGGTGATGGGGGAA
TCTCGGCTCCACAACCCCATGTATTATTTTCTGAGCGTTTTATCATTCCTGGATGCCTGCTATT
CTTCAGTTGTCACCCCAAAAATGTTGGTCAATTTCCTAGCAGAGGATAAATCCATTTCCTATCT
CGGATGTGCAGCACAGATGCTTCTCTTCGTTACTTTTGGAACCACAGAATGCTTTCTCTTGGCT
GCCATGGCTTATGACCGCTATGTAGCAATCTACAACCCTCTCCTGTATTCCGTGAGCATGTCAC
CCAGGGTCTATGTGCCACTCATCGTTGCTTCCTATGTTGGTGGCATTTTGCATGCTTCTGTACA
CACAGTGGCCACGTTCAGCCTATCCTTCTGTGCTTCCAATGAAATTAGACATGTCTTTTGTGAC
ATCCCTCCACTACTTGCCATTTCGTGTTCTGACACCCACACAAACCAGCTGCTGCTCTTCTACT
TCGTGGGCTCTATTGAGATAGTCACTATCCTCATTGTTCTGATCTCCTATGGTTTCATTCTCTT
GGCCATTCTGAACATCCATTCTGCCGAGGGGAGGCGGAAAGTCTTTTCTACGTGTGGTTCTCAC
CTAACTGGAGTGTCAATTTATCATGGAACCATCCTTTTCATATATATGAGACCAAGTTCCAGTT
ATGCTTTGGAGCATGACATGATAGTGTCAATATTTTACACGATTGTGATTCCTATGCTGAATCC
CATCATCTACAGTTTAAGGAACAAAGATGTAAAAGAGGCGATGAAGAAATTGTTTATGAGAAAT
TGGTTCTTAAGTAAAACACATAATTAG

hide sequence

RefSeq Acc Id:

XM_038425517 ⟹ XP_038281445

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	40,426,992 - 40,427,978 (+)	NCBI

RefSeq Acc Id:

XM_038501838 ⟹ XP_038357766

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	40,032,932 - 40,033,918 (+)	NCBI

RefSeq Acc Id:

XM_038564477 ⟹ XP_038420405

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	40,185,708 - 40,186,694 (+)	NCBI

RefSeq Acc Id:

XM_038628595 ⟹ XP_038484523

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	39,598,912 - 39,599,898 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013976391	(Get FASTA)	NCBI Sequence Viewer
	XP_038281445	(Get FASTA)	NCBI Sequence Viewer
	XP_038357766	(Get FASTA)	NCBI Sequence Viewer
	XP_038420405	(Get FASTA)	NCBI Sequence Viewer
	XP_038484523	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000035172.3
	ENSCAFP00040020374.1
	ENSCAFP00845009028.1

RefSeq Acc Id:

XP_013976391 ⟸ XM_014120916

- UniProtKB:

A0A8C0SFM0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPGFPSDLDLYRIQMKNVTEATMFILMGFTDDFEMQVFLFLLFLAIYLFTLIGNLGLVILVMGE
SRLHNPMYYFLSVLSFLDACYSSVVTPKMLVNFLAEDKSISYLGCAAQMLLFVTFGTTECFLLA
AMAYDRYVAIYNPLLYSVSMSPRVYVPLIVASYVGGILHASVHTVATFSLSFCASNEIRHVFCD
IPPLLAISCSDTHTNQLLLFYFVGSIEIVTILIVLISYGFILLAILNIHSAEGRRKVFSTCGSH
LTGVSIYHGTILFIYMRPSSSYALEHDMIVSIFYTIVIPMLNPIIYSLRNKDVKEAMKKLFMRN
WFLSKTHN

hide sequence

RefSeq Acc Id:

ENSCAFP00000035172 ⟸ ENSCAFT00000039336

RefSeq Acc Id:

XP_038357766 ⟸ XM_038501838

RefSeq Acc Id:

XP_038484523 ⟸ XM_038628595

RefSeq Acc Id:	XP_038281445 ⟸ XM_038425517
- UniProtKB:	A0A8C0SFM0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038420405 ⟸ XM_038564477
- UniProtKB:	A0A8C0LTT7 (UniProtKB/TrEMBL), A0A8C0SFM0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845009028 ⟸ ENSCAFT00845011556

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000046319	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040012742	UniProtKB/TrEMBL
	ENSCAFG00845006510	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000039336.4	UniProtKB/TrEMBL
	ENSCAFT00040023480.1	UniProtKB/TrEMBL
	ENSCAFT00845011556.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
NCBI Gene	LOC100685095	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 5T1-RELATED	UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C0LTT7	ENTREZGENE
	A0A8C0SFM0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N311_CANLF	UniProtKB/TrEMBL
	A0A8P0SQR5_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:96968	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-04-28	OR5T1	olfactory receptor family 5 subfamily T member 1	LOC100685095	olfactory receptor 5T1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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