AMHR2 (anti-Mullerian hormone receptor type 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: AMHR2 (anti-Mullerian hormone receptor type 2) Canis lupus familiaris
Analyze
Symbol: AMHR2
Name: anti-Mullerian hormone receptor type 2
RGD ID: 12396573
Description: ENCODES a protein that exhibits anti-Mullerian hormone receptor activity (ortholog); hormone binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN anti-Mullerian hormone receptor signaling pathway (ortholog); female gonad development (ortholog); male gonad development (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); dysgerminoma (ortholog); Endometrial Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); receptor complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anti-Muellerian hormone type-2 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,788,420 - 1,795,601 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,789,681 - 1,795,533 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,455,814 - 44,462,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,791,762 - 1,796,819 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,809,299 - 1,816,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,793,536 - 1,800,715 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,856,852 - 44,864,032 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:18723470   PMID:22301074   PMID:30032202   PMID:30173854  


Genomics

Comparative Map Data
AMHR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,788,420 - 1,795,601 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,789,681 - 1,795,533 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,455,814 - 44,462,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,791,762 - 1,796,819 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,809,299 - 1,816,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,793,536 - 1,800,715 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,856,852 - 44,864,032 (+)NCBIUU_Cfam_GSD_1.0
AMHR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,423,855 - 53,431,672 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,423,855 - 53,431,672 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,817,639 - 53,825,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,103,908 - 52,111,579 (+)NCBINCBI36Build 36hg18NCBI36
Build 341252,103,907 - 52,111,579NCBI
Celera1253,467,836 - 53,475,515 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,858,022 - 50,865,704 (+)NCBIHuRef
CHM1_11253,784,835 - 53,792,514 (+)NCBICHM1_1
T2T-CHM13v2.01253,389,898 - 53,397,715 (+)NCBIT2T-CHM13v2.0
Amhr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,353,437 - 102,363,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,353,802 - 102,363,068 (+)EnsemblGRCm39 Ensembl
GRCm3815102,445,002 - 102,454,640 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,445,367 - 102,454,633 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,275,798 - 102,285,070 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,273,454 - 102,282,664 (+)NCBIMGSCv36mm8
Celera15104,603,320 - 104,612,566 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.58NCBI
Amhr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,454,517 - 135,470,183 (+)NCBIGRCr8
mRatBN7.27133,579,152 - 133,588,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,579,393 - 133,588,258 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,335,126 - 135,343,991 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,564,494 - 137,573,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,550,745 - 137,559,612 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07144,052,202 - 144,060,678 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,052,061 - 144,060,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,844,072 - 141,852,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,203,832 - 141,212,653 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,280,268 - 141,289,089 (+)NCBI
Celera7130,006,948 - 130,015,487 (+)NCBICelera
Cytogenetic Map7q36NCBI
Amhr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458694,055 - 702,778 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458693,434 - 703,026 (+)NCBIChiLan1.0ChiLan1.0
AMHR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,750,644 - 40,762,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,747,448 - 40,759,581 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,323,133 - 35,331,092 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,107,363 - 36,115,175 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,107,501 - 36,115,175 (-)Ensemblpanpan1.1panPan2
Amhr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,452,033 - 62,462,933 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,705,350 - 10,713,517 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,706,043 - 10,712,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMHR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,642,823 - 18,648,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,642,212 - 18,648,859 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,078,369 - 19,085,012 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMHR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,524,864 - 49,534,774 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,525,641 - 49,534,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,524,251 - 196,533,349 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amhr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,520,572 - 1,530,908 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,520,450 - 1,535,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AMHR2
63 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2
Low 4 2 19 5 5 5 6 3 12 8 10 6
Below cutoff 1 3 1 1 1 1 3

Sequence


RefSeq Acc Id: ENSCAFT00000011129   ⟹   ENSCAFP00000010309
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl271,789,681 - 1,795,533 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068584   ⟹   ENSCAFP00000052775
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl271,789,681 - 1,795,255 (-)Ensembl
RefSeq Acc Id: XM_038437936   ⟹   XP_038293864
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0271,791,762 - 1,796,819 (-)NCBI
RefSeq Acc Id: XM_038512759   ⟹   XP_038368687
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1271,809,299 - 1,816,478 (-)NCBI
RefSeq Acc Id: XM_038577788   ⟹   XP_038433716
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02744,856,852 - 44,864,032 (+)NCBI
RefSeq Acc Id: XM_038640517   ⟹   XP_038496445
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0271,793,536 - 1,800,715 (-)NCBI
RefSeq Acc Id: XM_543632   ⟹   XP_543632
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1271,788,420 - 1,795,601 (-)NCBI
Dog10K_Boxer_Tasha2744,455,814 - 44,462,993 (+)NCBI
Sequence:
RefSeq Acc Id: XP_543632   ⟸   XM_543632
- Peptide Label: isoform X5
- UniProtKB: A0A8C0PXV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010309   ⟸   ENSCAFT00000011129
RefSeq Acc Id: ENSCAFP00000052775   ⟸   ENSCAFT00000068584
RefSeq Acc Id: XP_038368687   ⟸   XM_038512759
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038496445   ⟸   XM_038640517
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038293864   ⟸   XM_038437936
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038433716   ⟸   XM_038577788
- Peptide Label: isoform X4
- UniProtKB: A0A8C0PXV5 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006934 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025715 UniProtKB/TrEMBL
  ENSCAFG00040021228 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011129.5 UniProtKB/TrEMBL
  ENSCAFT00030047553.1 UniProtKB/TrEMBL
  ENSCAFT00040039401.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Anti-muellerian_hrmn_rcpt_II UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/TrEMBL
NCBI Gene AMHR2 ENTREZGENE
PANTHER ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR UniProtKB/TrEMBL
  TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PIRSF AMHRII UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
Superfamily-SCOP Protein kinase-like (PK-like) UniProtKB/TrEMBL
  Snake toxin-like UniProtKB/TrEMBL
UniProt A0A8C0PXV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TD47_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0N9D0 UniProtKB/TrEMBL
VGNC ID VGNC:37830 ENTREZGENE