GNG10 (G protein subunit gamma 10)

Gene: GNG10 (G protein subunit gamma 10) Canis lupus familiaris

Analyze

Symbol:

GNG10

Name:

G protein subunit gamma 10

RGD ID:

12394341

Description:

ENCODES a protein that exhibits G-protein beta-subunit binding (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN heterotrimeric G-protein complex (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

guanine nucleotide binding protein (G protein), gamma 10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like; LOC106559503; uncharacterized LOC106559503

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	47,283,272 - 47,284,375 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	47,283,272 - 47,284,369 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	64,681,047 - 64,687,575 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	67,403,953 - 67,410,435 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	67,403,989 - 67,409,523 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	65,920,726 - 65,927,265 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	65,944,246 - 65,950,784 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	66,634,242 - 66,640,794 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

signal transduction (IEA)

Cellular Component

heterotrimeric G-protein complex (IEA,ISO)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G-protein beta-subunit binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GNG10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	47,283,272 - 47,284,375 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	47,283,272 - 47,284,369 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	64,681,047 - 64,687,575 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	67,403,953 - 67,410,435 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	67,403,989 - 67,409,523 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	65,920,726 - 65,927,265 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	65,944,246 - 65,950,784 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	66,634,242 - 66,640,794 (+)	NCBI		UU_Cfam_GSD_1.0

GNG10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	111,661,605 - 111,670,226 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	111,661,605 - 111,670,226 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	114,423,885 - 114,432,506 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	113,463,682 - 113,472,347 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	84,922,924 - 84,931,584 (+)	NCBI		Celera
Cytogenetic Map	9	q31.3	NCBI
HuRef	9	84,022,371 - 84,031,039 (+)	NCBI		HuRef
CHM1_1	9	114,570,242 - 114,578,906 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	123,832,965 - 123,841,586 (+)	NCBI		T2T-CHM13v2.0

Gng10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	59,035,156 - 59,041,899 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	59,035,088 - 59,041,903 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	59,035,156 - 59,041,899 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	59,035,088 - 59,041,903 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	59,048,028 - 59,054,771 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	59,129,210 - 59,135,953 (+)	NCBI		MGSCv36	mm8
Celera	4	58,945,401 - 58,952,110 (+)	NCBI		Celera
Cytogenetic Map	4	B3	NCBI
cM Map	4	32.36	NCBI

Gng10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	78,651,167 - 78,658,060 (+)	NCBI		GRCr8
mRatBN7.2	5	73,856,124 - 73,863,017 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	73,856,000 - 73,864,390 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	5	73,856,164 - 73,863,012 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	75,757,386 - 75,764,290 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	77,579,006 - 77,585,910 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	77,551,158 - 77,558,064 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	76,182,100 - 76,189,014 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	76,182,121 - 76,189,013 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	80,325,898 - 80,332,791 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	77,083,335 - 77,090,218 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	77,092,258 - 77,092,346 (+)	NCBI
Celera	5	72,678,328 - 72,685,217 (+)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

Gng10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955419	15,650,973 - 15,653,122 (-)	NCBI	ChiLan1.0	ChiLan1.0

GNG10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	27,759,918 - 27,775,260 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	27,762,264 - 27,771,186 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	82,791,821 - 82,800,763 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	110,953,338 - 110,962,288 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

LOC101964645
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	165,243,555 - 165,244,170 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004937297	89,279 - 90,425 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNG10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	252,453,107 - 252,460,315 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	252,453,009 - 252,459,978 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	283,246,536 - 283,266,474 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GNG10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	27,837,287 - 27,846,217 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	27,836,526 - 27,846,207 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666035	14,935,965 - 14,945,093 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gng10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	23,338,452 - 23,345,576 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	23,338,452 - 23,345,602 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GNG10
19 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	21	5	6	5	6	6	12	8	10	6
Low			1	1		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001205002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN874906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN904736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000030695 ⟹ ENSCAFP00000028529

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	9	47,283,272 - 47,284,369 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845009961 ⟹ ENSCAFP00845007771

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	67,403,989 - 67,409,523 (+)	Ensembl

RefSeq Acc Id:

NM_001205002 ⟹ NP_001191931

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	47,283,272 - 47,284,375 (+)	NCBI
Dog10K_Boxer_Tasha	11	64,681,047 - 64,687,575 (+)	NCBI
ROS_Cfam_1.0	11	67,403,953 - 67,410,435 (+)	NCBI
UMICH_Zoey_3.1	11	65,920,726 - 65,927,265 (+)	NCBI
UNSW_CanFamBas_1.0	11	65,944,246 - 65,950,784 (+)	NCBI
UU_Cfam_GSD_1.0	11	66,634,242 - 66,640,794 (+)	NCBI

Sequence:

show sequence

CGGCCTCGCGGCTCCCGCACGTCGCTCCGCCGCCCTCGGAGCCCTGCGCCGCCGCCATGTCTTC
CGGCGCCAGCGTGAACGCCCTGCAGCGCCTGGTGGAGCAGCTCAAGCTGGAGGCCGGCGTGGAG
AGGATCAAGGTCTCGCAGGCAGCTGCAGAGCTTCAACAGTACTGCATGCAGAATGCCTGCAAGG
ATGCCCTGCTGGTAGGTGTTCCAGCTGGAAGCAACCCCTTCCGGGAGCCCAGATCCTGTGCTTT
ATTCTAAAGGCGGTAAGGAAGGAGCTCACTGAGGAATGCTTTCAGGCGCAAAGTGATGAATAAC
TAACTGCCTCCAAGTCTCAAGAAAACACTTTTCTCCAGCCAAACAACTTTTACATATTTCAGAC
CTTTCCTTACCTATTTCAGATCCTTCAGATCCTTTTCTTTCCCAGAATTTCAGCCAAAATTCTA
TAGAAATTGGTGAGTTTCTACTCAGATAAGGAAACGGAGTGAGGAGAAGACTTTAGATAATAAT
GGCCAGACTTTTGGTAAAATGCTTTTATATTTAAGACAAAAATGTTACCACCAAATACACCTCT
TTCATAAGTGAATTACTGGTGTTTCTATACCTGGAATATTATGTTTGTTTTATTTACTGGATGT
TTACATTTTGGGAAGGCAAACATTTTTGTTTGTTAAAAAATTATTTGTAATTTGTTGTTCCTAA
GATTTTTATACCATAACAAAACTTGTTCTTTTCTCATGAATTTGCAGTTTCTAAATAAGACAAG
CAAGTATAAAACTGGGGGAGAACAGACTTTATTAATTAAATTATGTCTTGATTTTTCTAAACGA
GAGGACTATTTGTAACACTAAATATGGGAGCTATTTCTTAACAAACTTGTTTGGAAAGATTCAT
GTTATGTTGTGTATTAGATTGCTCCATCTTGTGTATGAAGCAGATTTGGTCTTTGTCTTAAGTT
CCTCTACTTTATAGTTGTGGATGTACTTTGTTAAAAAAAACCAACAACACACACACAGAAACCT
ACATTTCATGTCTTTAAAAAATGTTTAAATGTTATCTTCGGAACATTGCAAATGATTAAAAACA
AAATAATGTGAAAATAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001191931	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000028529.3
	ENSCAFP00000073412.1
	ENSCAFP00030013467.1
	ENSCAFP00040008821.1
	ENSCAFP00040022579.1
	ENSCAFP00845007771
	ENSCAFP00845007771.1
	ENSCAFP00845021608.1

RefSeq Acc Id:	NP_001191931 ⟸ NM_001205002
- UniProtKB:	A0A8C0QD15 (UniProtKB/TrEMBL), A0A8C0LEZ3 (UniProtKB/TrEMBL), A0A8I3N081 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSGASVNALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRS CALF hide sequence

RefSeq Acc Id:

ENSCAFP00000028529 ⟸ ENSCAFT00000030695

RefSeq Acc Id:

ENSCAFP00845007771 ⟸ ENSCAFT00845009961

Protein Domains

G protein gamma

Promoters

RGD ID:

13684725

Promoter ID:

EPDNEW_C2794

Type:

initiation region

Name:

GNG10_1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	47,283,303 - 47,283,363	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019322	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00000051067	UniProtKB/TrEMBL
	ENSCAFG00030008396	UniProtKB/TrEMBL
	ENSCAFG00040005418	UniProtKB/TrEMBL
	ENSCAFG00040014054	UniProtKB/TrEMBL
	ENSCAFG00845005613	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSCAFG00845015401	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000030695.5	UniProtKB/TrEMBL
	ENSCAFT00000106294.1	UniProtKB/TrEMBL
	ENSCAFT00030015443.1	UniProtKB/TrEMBL
	ENSCAFT00040010170.1	UniProtKB/TrEMBL
	ENSCAFT00040025959.1	UniProtKB/TrEMBL
	ENSCAFT00845009961	ENTREZGENE
	ENSCAFT00845009961.1	UniProtKB/TrEMBL
	ENSCAFT00845027464.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.260.10	UniProtKB/TrEMBL
InterPro	G-protein_gamma-like_dom	UniProtKB/TrEMBL
	GGL_sf	UniProtKB/TrEMBL
	Gprotein-gamma	UniProtKB/TrEMBL
KEGG Report	cfa:100534634	UniProtKB/TrEMBL
NCBI Gene	GNG10	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(O) SUBUNIT GAMMA-10	UniProtKB/TrEMBL
	PTHR13809	UniProtKB/TrEMBL
Pfam	G-gamma	UniProtKB/TrEMBL
PRINTS	GPROTEING	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_GAMMA	UniProtKB/TrEMBL
SMART	G_gamma	UniProtKB/TrEMBL
	GGL	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48670	UniProtKB/TrEMBL
UniProt	A0A8C0LEZ3	ENTREZGENE
	A0A8C0QD15	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3N081	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:97200	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-14	GNG10	G protein subunit gamma 10	LOC106559503	uncharacterized LOC106559503	Data merged from RGD:12292461	737654	PROVISIONAL
2017-09-12	GNG10	G protein subunit gamma 10		guanine nucleotide binding protein (G protein), gamma 10	Symbol and/or name change	5135510	APPROVED
2017-09-12	LOC106559503	uncharacterized LOC106559503		guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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