OR5K8 (olfactory receptor family 5 subfamily K member 8) - Rat Genome Database

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Gene: OR5K8 (olfactory receptor family 5 subfamily K member 8) Canis lupus familiaris
Analyze
Symbol: OR5K8
Name: olfactory receptor family 5 subfamily K member 8
RGD ID: 12393238
Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC100684213; olfactory receptor 5K3-like
RGD Orthologs
Human
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.0335,401,600 - 5,402,528 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1335,276,894 - 5,277,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0335,339,565 - 5,340,494 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0335,617,299 - 5,618,228 (+)NCBIUU_Cfam_GSD_1.0


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OR5K8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.0335,401,600 - 5,402,528 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1335,276,894 - 5,277,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0335,339,565 - 5,340,494 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0335,617,299 - 5,618,228 (+)NCBIUU_Cfam_GSD_1.0
OR5K3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38398,390,666 - 98,391,631 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl398,390,666 - 98,391,631 (+)EnsemblGRCh38hg38GRCh38
GRCh37398,109,510 - 98,110,475 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36399,592,200 - 99,593,165 (+)NCBINCBI36Build 36hg18NCBI36
Build 34399,592,199 - 99,593,165NCBI
Celera396,501,349 - 96,502,314 (+)NCBICelera
Cytogenetic Map3q11.2NCBI
HuRef395,481,593 - 95,482,558 (+)NCBIHuRef
CHM1_1398,072,555 - 98,073,520 (+)NCBICHM1_1
T2T-CHM13v2.03101,094,360 - 101,095,325 (+)NCBIT2T-CHM13v2.0
LOC119625674
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604184,127,557 - 84,128,528 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system reproductive system adipose tissue
High
Medium
Low
Below cutoff 2 1 1 8 1

Sequence


Reference Sequences
RefSeq Acc Id: NM_001388965   ⟹   NP_001375894
RefSeq Status: INFERRED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0335,401,600 - 5,402,528 (+)NCBI
UMICH_Zoey_3.1335,276,894 - 5,277,823 (+)NCBI
UNSW_CanFamBas_1.0335,339,565 - 5,340,494 (+)NCBI
UU_Cfam_GSD_1.0335,617,299 - 5,618,228 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001375894 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030031001.1
Reference Protein Sequences
RefSeq Acc Id: NP_001375894   ⟸   NM_001388965
- UniProtKB: A0A8C0K6U8 (UniProtKB/TrEMBL),   A0A8C0P7S7 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030019337 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030035544.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene LOC100684213 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 5K3 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0K6U8 ENTREZGENE
  A0A8C0P7S7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-11-24 OR5K8  olfactory receptor family 5 subfamily K member 8  LOC100684213  olfactory receptor 5K3-like  Symbol and/or name change 5135510 APPROVED