SLC35C2 (solute carrier family 35 member C2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: SLC35C2 (solute carrier family 35 member C2) Canis lupus familiaris
Analyze
Symbol: SLC35C2
Name: solute carrier family 35 member C2
RGD ID: 12392376
Description: ENCODES a protein that exhibits antiporter activity (inferred); INVOLVED IN fucosylation (ortholog); negative regulation of gene expression (ortholog); positive regulation of Notch signaling pathway (ortholog); ASSOCIATED WITH focal epilepsy (ortholog); genetic disease (ortholog); FOUND IN cis-Golgi network (inferred); endoplasmic reticulum-Golgi intermediate compartment (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,584,040 - 33,592,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,584,082 - 33,597,571 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2433,110,131 - 33,118,568 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,293,642 - 34,307,238 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,293,273 - 34,307,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,551,599 - 33,565,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,667,464 - 33,681,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,206,604 - 34,220,193 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC35C2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,584,040 - 33,592,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,584,082 - 33,597,571 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2433,110,131 - 33,118,568 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,293,642 - 34,307,238 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,293,273 - 34,307,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,551,599 - 33,565,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,667,464 - 33,681,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,206,604 - 34,220,193 (-)NCBIUU_Cfam_GSD_1.0
SLC35C2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,345,984 - 46,364,425 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,345,980 - 46,364,458 (-)EnsemblGRCh38hg38GRCh38
GRCh372044,974,623 - 44,993,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,411,584 - 44,426,471 (-)NCBINCBI36Build 36hg18NCBI36
Celera2041,689,609 - 41,704,478 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,719,084 - 41,733,993 (-)NCBIHuRef
CHM1_12044,880,806 - 44,895,718 (-)NCBICHM1_1
T2T-CHM13v2.02048,082,033 - 48,100,454 (-)NCBIT2T-CHM13v2.0
Slc35c2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,118,442 - 165,129,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,118,474 - 165,129,789 (-)EnsemblGRCm39 Ensembl
GRCm382165,276,522 - 165,287,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,276,554 - 165,287,869 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,102,056 - 165,113,327 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,967,761 - 164,979,032 (-)NCBIMGSCv36mm8
Celera2171,218,946 - 171,230,221 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.53NCBI
Slc35c2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,431,688 - 174,442,852 (-)NCBIGRCr8
mRatBN7.23154,012,262 - 154,023,549 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,012,416 - 154,023,488 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,821,068 - 157,832,160 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,320,048 - 166,331,142 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,061,398 - 164,072,524 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,801,194 - 161,812,318 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,801,197 - 161,812,291 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,986,102 - 167,997,221 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,317,336 - 156,328,430 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,223,405 - 156,234,465 (-)NCBI
Celera3152,611,587 - 152,622,681 (-)NCBICelera
Cytogenetic Map3q42NCBI
Slc35c2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,984,237 - 10,996,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,984,675 - 10,996,707 (+)NCBIChiLan1.0ChiLan1.0
SLC35C2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,089,577 - 52,104,164 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12052,082,690 - 52,097,270 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,686,735 - 42,701,321 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,772,037 - 43,786,549 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,772,681 - 43,780,671 (-)Ensemblpanpan1.1panPan2
Slc35c2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,293,387 - 191,306,127 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,747,027 - 6,760,072 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,747,067 - 6,759,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC35C2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,512,803 - 48,525,143 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,512,442 - 48,525,161 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21754,155,746 - 54,168,409 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC35C2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,520,381 - 17,534,066 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,525,182 - 17,534,215 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,154,567 - 66,168,465 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc35c2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,268,220 - 8,281,912 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,268,219 - 8,281,085 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC35C2
93 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 10 6
Low 5 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022409055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_847903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000016288   ⟹   ENSCAFP00000015067
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2433,584,082 - 33,597,571 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033108   ⟹   ENSCAFP00845025919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2434,293,273 - 34,307,190 (-)Ensembl
RefSeq Acc Id: XM_022409055   ⟹   XP_022264763
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12433,584,040 - 33,592,408 (-)NCBI
Dog10K_Boxer_Tasha2433,110,131 - 33,118,555 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038434008   ⟹   XP_038289936
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02434,293,642 - 34,307,238 (-)NCBI
RefSeq Acc Id: XM_038434009   ⟹   XP_038289937
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02434,293,642 - 34,307,238 (-)NCBI
RefSeq Acc Id: XM_038434010   ⟹   XP_038289938
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02434,293,642 - 34,307,206 (-)NCBI
RefSeq Acc Id: XM_038457892   ⟹   XP_038313820
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2433,110,131 - 33,118,568 (-)NCBI
RefSeq Acc Id: XM_038509167   ⟹   XP_038365095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12433,551,599 - 33,565,188 (-)NCBI
RefSeq Acc Id: XM_038509168   ⟹   XP_038365096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12433,551,599 - 33,565,188 (-)NCBI
RefSeq Acc Id: XM_038509169   ⟹   XP_038365097
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12433,551,599 - 33,565,156 (-)NCBI
RefSeq Acc Id: XM_038572500   ⟹   XP_038428428
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02434,206,604 - 34,220,193 (-)NCBI
RefSeq Acc Id: XM_038572501   ⟹   XP_038428429
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02434,206,604 - 34,220,193 (-)NCBI
RefSeq Acc Id: XM_038572502   ⟹   XP_038428430
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02434,206,604 - 34,220,161 (-)NCBI
RefSeq Acc Id: XM_038636773   ⟹   XP_038492701
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02433,667,464 - 33,681,037 (-)NCBI
RefSeq Acc Id: XM_038636774   ⟹   XP_038492702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02433,667,464 - 33,681,037 (-)NCBI
RefSeq Acc Id: XM_038636775   ⟹   XP_038492703
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02433,667,464 - 33,681,005 (-)NCBI
RefSeq Acc Id: XM_847903   ⟹   XP_852996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12433,584,040 - 33,592,408 (-)NCBI
Dog10K_Boxer_Tasha2433,110,131 - 33,118,555 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_852996   ⟸   XM_847903
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QD29 (UniProtKB/TrEMBL),   A0A8C0KQL1 (UniProtKB/TrEMBL),   A0A8I3NX77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022264763   ⟸   XM_022409055
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000015067   ⟸   ENSCAFT00000016288
RefSeq Acc Id: XP_038365096   ⟸   XM_038509168
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365095   ⟸   XM_038509167
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038365097   ⟸   XM_038509169
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038492702   ⟸   XM_038636774
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492701   ⟸   XM_038636773
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492703   ⟸   XM_038636775
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038289937   ⟸   XM_038434009
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289936   ⟸   XM_038434008
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QD29 (UniProtKB/TrEMBL),   A0A8C0KQL1 (UniProtKB/TrEMBL),   A0A8I3NX77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038289938   ⟸   XM_038434010
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038313820   ⟸   XM_038457892
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038428429   ⟸   XM_038572501
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038428428   ⟸   XM_038572500
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KQL1 (UniProtKB/TrEMBL),   A0A8C0QD29 (UniProtKB/TrEMBL),   A0A8I3NX77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428430   ⟸   XM_038572502
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCAFP00845025919   ⟸   ENSCAFT00845033108
Protein Domains
Sugar phosphate transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010265 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019589 UniProtKB/TrEMBL
  ENSCAFG00040006434 UniProtKB/TrEMBL
  ENSCAFG00845018711 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016288.5 UniProtKB/TrEMBL
  ENSCAFT00030036054.1 UniProtKB/TrEMBL
  ENSCAFT00040012022.1 UniProtKB/TrEMBL
  ENSCAFT00845033108 ENTREZGENE
  ENSCAFT00845033108.1 UniProtKB/TrEMBL
InterPro Sugar_P_trans_dom UniProtKB/TrEMBL
NCBI Gene SLC35C2 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 35 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 35 MEMBER C2 UniProtKB/TrEMBL
Pfam TPT UniProtKB/TrEMBL
Superfamily-SCOP Multidrug resistance efflux transporter EmrE UniProtKB/TrEMBL
UniProt A0A8C0KQL1 ENTREZGENE
  A0A8C0QD29 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NX77 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46369 ENTREZGENE