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Gene: UPB1 (beta-ureidopropionase 1) Canis lupus familiaris

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Symbol:

UPB1

Name:

beta-ureidopropionase 1

RGD ID:

12390517

Description:

ENCODES a protein that exhibits beta-ureidopropionase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN beta-alanine metabolic process (ortholog); in utero embryonic development (ortholog); liver development (ortholog); PARTICIPATES IN beta-alanine metabolic pathway; beta-ureidopropionase deficiency pathway; carnosinemia pathway; ASSOCIATED WITH autistic disorder (ortholog); Beta-Ureidopropionase Deficiency (ortholog); celiac disease (ortholog); FOUND IN cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

beta-ureidopropionase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UPB1 (beta-ureidopropionase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Upb1 (ureidopropionase, beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Upb1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Upb1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UPB1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Upb1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UPB1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UPB1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Upb1 (beta-ureidopropionase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	28,194,968 - 28,225,977 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	28,195,081 - 28,225,567 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	27,269,282 - 27,301,115 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	29,598,247 - 29,630,273 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	29,599,300 - 29,630,269 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	27,681,607 - 27,713,443 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	27,298,626 - 27,330,446 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	28,288,066 - 28,320,106 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Beta-Ureidopropionase Deficiency (ISO)

celiac disease (ISO)

disease of metabolism (ISO)

epilepsy (ISO)

genetic disease (ISO)

schizophrenia (ISO)

West syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

beta-alanine biosynthetic process via 3-ureidopropionate (IBA,IEA)

beta-alanine metabolic process (ISO)

CMP catabolic process (IEA)

dCMP catabolic process (IEA)

dUMP catabolic process (IEA)

in utero embryonic development (ISO)

liver development (ISO)

protein homooligomerization (IEA)

protein homotetramerization (IEA)

pyrimidine nucleoside catabolic process (IEA)

UMP catabolic process (IEA)

Cellular Component

cytosol (IEA,ISO)

Molecular Function

beta-ureidopropionase activity (IBA,IEA,ISO)

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IEA)

protein homodimerization activity (IEA)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

beta-alanine metabolic pathway (ISO)

beta-ureidopropionase deficiency pathway (ISO)

carnosinemia pathway (ISO)

dihydropyrimidinase deficiency pathway (ISO)

GABA aminotransferase deficiency pathway (ISO)

mitochondrial neurogastrointestinal encephalopathy syndrome pathway (ISO)

orotic aciduria 1 pathway (ISO)

pyrimidine metabolic pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

UPB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	28,194,968 - 28,225,977 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	28,195,081 - 28,225,567 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	27,269,282 - 27,301,115 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	29,598,247 - 29,630,273 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	29,599,300 - 29,630,269 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	27,681,607 - 27,713,443 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	27,298,626 - 27,330,446 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	28,288,066 - 28,320,106 (+)	NCBI		UU_Cfam_GSD_1.0

UPB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	24,495,332 - 24,528,390 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	24,494,107 - 24,528,390 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	24,891,300 - 24,924,358 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	23,221,251 - 23,252,553 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	23,215,804 - 23,247,106	NCBI
Celera	22	8,690,987 - 8,722,274 (+)	NCBI		Celera
Cytogenetic Map	22	q11.23	NCBI
HuRef	22	7,840,918 - 7,872,203 (+)	NCBI		HuRef
CHM1_1	22	24,849,971 - 24,881,302 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	24,956,949 - 24,989,995 (+)	NCBI		T2T-CHM13v2.0

Upb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	75,242,745 - 75,277,513 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	75,236,949 - 75,277,513 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	75,406,911 - 75,441,679 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	75,401,115 - 75,441,679 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	74,869,779 - 74,902,942 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	74,846,181 - 74,883,913 (+)	NCBI		MGSCv36	mm8
Celera	10	76,453,987 - 76,488,021 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	38.53	NCBI

Upb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	13,216,693 - 13,243,016 (-)	NCBI		GRCr8
mRatBN7.2	20	13,217,252 - 13,243,590 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	13,217,258 - 13,243,590 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	13,923,828 - 13,950,151 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	13,284,776 - 13,311,090 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	13,757,287 - 13,783,611 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	14,167,383 - 14,193,724 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	14,167,586 - 14,193,690 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	16,352,599 - 16,378,743 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	13,715,995 - 13,743,261 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	13,716,221 - 13,743,488 (-)	NCBI
Celera	20	14,703,097 - 14,729,538 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Upb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	7,961,264 - 7,995,946 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	7,961,296 - 7,992,235 (+)	NCBI	ChiLan1.0	ChiLan1.0

UPB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	34,283,288 - 34,320,118 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	37,013,937 - 37,053,257 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	5,300,686 - 5,332,735 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	22,138,989 - 22,197,360 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	22,166,370 - 22,197,360 (+)	Ensembl	panpan1.1		panPan2

Upb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	142,039,199 - 142,085,682 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936619	668,351 - 696,306 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936619	668,380 - 713,720 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UPB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	49,533,231 - 49,565,075 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	49,533,208 - 49,561,518 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	52,975,014 - 53,003,329 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UPB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	7,605,999 - 7,639,339 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	7,605,537 - 7,639,017 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666085	4,807,773 - 4,841,973 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Upb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	9,911,448 - 9,940,537 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	9,911,323 - 9,940,770 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in UPB1
386 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022410326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038459201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038459202	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038512289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038512290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038512291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038575789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038575790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038575791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038640000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038640001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038640002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_543524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000021967 ⟹ ENSCAFP00000020398

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	28,195,081 - 28,225,567 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000049172 ⟹ ENSCAFP00000042140

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	28,201,903 - 28,225,567 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039741 ⟹ ENSCAFP00845031130

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,599,300 - 29,630,269 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039820 ⟹ ENSCAFP00845031186

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,605,512 - 29,630,269 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039904 ⟹ ENSCAFP00845031247

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,605,512 - 29,630,269 (+)	Ensembl

RefSeq Acc Id:

XM_038437418 ⟹ XP_038293346

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	26	29,599,224 - 29,630,273 (+)	NCBI

RefSeq Acc Id:

XM_038437419 ⟹ XP_038293347

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	26	29,598,647 - 29,630,273 (+)	NCBI

RefSeq Acc Id:

XM_038437420 ⟹ XP_038293348

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	26	29,598,247 - 29,630,273 (+)	NCBI

RefSeq Acc Id:

XM_038459201 ⟹ XP_038315129

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	26	27,269,683 - 27,301,115 (+)	NCBI

RefSeq Acc Id:

XM_038459202 ⟹ XP_038315130

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	26	27,269,282 - 27,301,115 (+)	NCBI

RefSeq Acc Id:

XM_038512289 ⟹ XP_038368217

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	26	27,682,584 - 27,713,443 (+)	NCBI

RefSeq Acc Id:

XM_038512290 ⟹ XP_038368218

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	26	27,682,007 - 27,713,443 (+)	NCBI

RefSeq Acc Id:

XM_038512291 ⟹ XP_038368219

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	26	27,681,607 - 27,713,443 (+)	NCBI

RefSeq Acc Id:

XM_038575789 ⟹ XP_038431717

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	26	28,289,043 - 28,320,106 (+)	NCBI

RefSeq Acc Id:

XM_038575790 ⟹ XP_038431718

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	26	28,288,466 - 28,320,106 (+)	NCBI

RefSeq Acc Id:

XM_038575791 ⟹ XP_038431719

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	26	28,288,066 - 28,320,106 (+)	NCBI

RefSeq Acc Id:

XM_038640000 ⟹ XP_038495928

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	26	27,299,603 - 27,330,446 (+)	NCBI

RefSeq Acc Id:

XM_038640001 ⟹ XP_038495929

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	26	27,299,027 - 27,330,446 (+)	NCBI

RefSeq Acc Id:

XM_038640002 ⟹ XP_038495930

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	26	27,298,626 - 27,330,446 (+)	NCBI

RefSeq Acc Id:

XM_543524 ⟹ XP_543524

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	26	28,194,974 - 28,225,977 (+)	NCBI
Dog10K_Boxer_Tasha	26	27,270,259 - 27,301,115 (+)	NCBI

Sequence:

show sequence

GCGGACCTTGTGGCCGGCTCCTCCTTCCCCTCTTACTGGGTGGGGGCAAAGGGTAGGCCGTGTT
AGTCTGGACATCAGCCCCTCATCTGCGCCTGCGGACTCTGGCCATGGCGGGATCTGAGTGGGAG
TCGCTGGAGCAGTGCTTGGAGAAGCACCTGCCACCCGCAGACTTGCGGGAGGTGAAACGCATTC
TCTATGGCAAGGAAACCAGGAAGCTTGATCTGCCCAGCAGGGCTTTTGAAGCCGCCTTGGAAGG
GGACTTTGAGCTACAGGGATATGCCTTTGAGGCAGCAGAGGAGCAGCTGAGGCCACCTCGGACT
GTGCGTGTGGGACTTGTTCAGAACAAAACTCCCCTGCCTGCAGATGCCCCTGTGGCAAAACAGG
TCACTGCCCTTCATAGACGCATAGAAGCCATCGTAGAGGTGGCTGCAGTGTGTGGAGTGAACAT
CATCTGTTTCCAGGAAGCATGGACTATGCCCTTTGCTTTCTGTACAAGAGAGAAGCTTCCTTGG
ACGGAATTTGCTGAGTCAGCCGAGGACGGACCCACCACCAGATTCTGTCAGAAGCTGGCAAAGA
AGCATGACATGGTGGTGGTATCCCCCATCCTGGAACGAGATAGGGAGCATGGGGACATTTTGTG
GAACACAGCCGTGGTAATCTCCAATTCTGGAGCAGTCCTGGGAAAGACCAGGAAAAACCACATC
CCCAGAGTGGGTGACTTCAATGAGTCAACTTACTACATGGAGGGAAACCTTGGACACCCGGTGT
TCCAGACTCAGTTTGGGAAGATTGCAGTGAACATTTGCTATGGGCGTCACCACCCTCTCAACTG
GCTCATGTACAGCATCAACGGAGCTGAGATCATCTTCAACCCGTCAGCCACTATCGGAGCACTC
AGCGAGTCCCTGTGGCCAGTTGAGGCCAGAAACGCAGCCATTGCGAATCACTGCTTTACTTGTG
CCATCAACCGTGTAGGCCAGGAGCACTTTCCCAATGAGTTTACCTCTGGAGATGGGAAGAAAGC
TCACCGGGACTTTGGCTACTTTTATGGCTCGAGCTACGTGGCGGCCCCTGACAGCAGTCGCACT
CCTGGGCTCTCCCGCAACAAGGACGGGCTGCTGGTGGCTGAGCTCGACCTGAACCTCTGCCGGC
AGGTGAATGACATCTGGAACTTCAAGATGACCGGCAGATATGAGATGTATGCTCAGGAGCTTGC
AGAAGCCATCAAACCCAACTACAGCCCCAATGTCGTGAAAGAGTAGCTGGATTTTAGCTCCTGC
CTGCCAAGGATGGCACCTCTGCCCCTAGCAGATCTGCAAGTACAGCAGGCTTTACATGTGCAAG
TTCTCCCCGGTGGTATCCTGGTAACATTTCTGTCCACATAGGTTTAAAAACACCTAGACACGGG
GAGATGCCTGGGTGGCTCAGCAGTTGAGCCTCTGCCTTGGGCTCAGGGCATGATCCTGGAGCCC
CAGGATCGAGTCCCACATCGGGCTCCCTGCATGGAGCCTGCTTCTCCCTCTGCCTATGTCTCTA
CCTCTCTCCTTCTGTGTCTCTCATGAATAAATAAATAAAATATTTTTTAAAAAAAGAAAGAAAG
GAAGAAAAATGCCTAGATAGGGAGGGTATATTGAAGAATAACTGTCCAGTGGGTATGAGTTTCC
TTCCTGGATGATGAAATCTTTTGGGCTTACACAGAAGTGTTGCTTACACAACATTGTGAATGTG
CTAATGTAGAATGCCACTCAATTGTATACTTTAAAATGGCTAAATTTATGTCATGTGAATTTTA
CCCCCATTAAAAAAAAAAATCCGGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038293346	(Get FASTA)	NCBI Sequence Viewer
	XP_038293347	(Get FASTA)	NCBI Sequence Viewer
	XP_038293348	(Get FASTA)	NCBI Sequence Viewer
	XP_038315129	(Get FASTA)	NCBI Sequence Viewer
	XP_038315130	(Get FASTA)	NCBI Sequence Viewer
	XP_038368217	(Get FASTA)	NCBI Sequence Viewer
	XP_038368218	(Get FASTA)	NCBI Sequence Viewer
	XP_038368219	(Get FASTA)	NCBI Sequence Viewer
	XP_038431717	(Get FASTA)	NCBI Sequence Viewer
	XP_038431718	(Get FASTA)	NCBI Sequence Viewer
	XP_038431719	(Get FASTA)	NCBI Sequence Viewer
	XP_038495928	(Get FASTA)	NCBI Sequence Viewer
	XP_038495929	(Get FASTA)	NCBI Sequence Viewer
	XP_038495930	(Get FASTA)	NCBI Sequence Viewer
	XP_543524	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000020398.2
	ENSCAFP00000042140.2
	ENSCAFP00000074658.1
	ENSCAFP00030035207.1
	ENSCAFP00040029704.1
	ENSCAFP00040029744.1
	ENSCAFP00845031130
	ENSCAFP00845031130.1
	ENSCAFP00845031186.1
	ENSCAFP00845031247
	ENSCAFP00845031247.1

RefSeq Acc Id:	XP_543524 ⟸ XM_543524
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RQR4 (UniProtKB/TrEMBL), A0A8I3PKE2 (UniProtKB/TrEMBL), A0A8C0T3I6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGSEWESLEQCLEKHLPPADLREVKRILYGKETRKLDLPSRAFEAALEGDFELQGYAFEAAEE QLRPPRTVRVGLVQNKTPLPADAPVAKQVTALHRRIEAIVEVAAVCGVNIICFQEAWTMPFAFC TREKLPWTEFAESAEDGPTTRFCQKLAKKHDMVVVSPILERDREHGDILWNTAVVISNSGAVLG KTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGKIAVNICYGRHHPLNWLMYSINGAEIIFNP SATIGALSESLWPVEARNAAIANHCFTCAINRVGQEHFPNEFTSGDGKKAHRDFGYFYGSSYVA APDSSRTPGLSRNKDGLLVAELDLNLCRQVNDIWNFKMTGRYEMYAQELAEAIKPNYSPNVVKE hide sequence

Ensembl Acc Id:

ENSCAFP00000042140 ⟸ ENSCAFT00000049172

Ensembl Acc Id:

ENSCAFP00000020398 ⟸ ENSCAFT00000021967

RefSeq Acc Id:	XP_038368219 ⟸ XM_038512291
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038368218 ⟸ XM_038512290
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038368217 ⟸ XM_038512289
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038495930 ⟸ XM_038640002
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038495929 ⟸ XM_038640001
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038495928 ⟸ XM_038640000
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038293348 ⟸ XM_038437420
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293347 ⟸ XM_038437419
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293346 ⟸ XM_038437418
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RQR4 (UniProtKB/TrEMBL), A0A8I3PKE2 (UniProtKB/TrEMBL), A0A8C0T3I6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038315130 ⟸ XM_038459202
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038315129 ⟸ XM_038459201
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038431719 ⟸ XM_038575791
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038431718 ⟸ XM_038575790
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JZL8 (UniProtKB/TrEMBL), A0A8I3S5R8 (UniProtKB/TrEMBL), A0A8I3S5S8 (UniProtKB/TrEMBL), A0A8P0PRA3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038431717 ⟸ XM_038575789
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0RQR4 (UniProtKB/TrEMBL), A0A8C0T3I6 (UniProtKB/TrEMBL), A0A8I3PKE2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845031247 ⟸ ENSCAFT00845039904

Ensembl Acc Id:

ENSCAFP00845031130 ⟸ ENSCAFT00845039741

Ensembl Acc Id:

ENSCAFP00845031186 ⟸ ENSCAFT00845039820

Protein Domains

CN hydrolase

Promoters

RGD ID:

13688017

Promoter ID:

EPDNEW_C6085

Type:

initiation region

Name:

UPB1_1

Description:

beta-ureidopropionase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	26	28,195,038 - 28,195,098	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013843	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021950	UniProtKB/TrEMBL
	ENSCAFG00040018296	UniProtKB/TrEMBL
	ENSCAFG00845022513	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000021967.5	UniProtKB/TrEMBL
	ENSCAFT00000049172.3	UniProtKB/TrEMBL
	ENSCAFT00000105865.1	UniProtKB/TrEMBL
	ENSCAFT00030040338.1	UniProtKB/TrEMBL
	ENSCAFT00040034127.1	UniProtKB/TrEMBL
	ENSCAFT00040034169.1	UniProtKB/TrEMBL
	ENSCAFT00845039741	ENTREZGENE
	ENSCAFT00845039741.1	UniProtKB/TrEMBL
	ENSCAFT00845039820.1	UniProtKB/TrEMBL
	ENSCAFT00845039904	ENTREZGENE
	ENSCAFT00845039904.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.110.10	UniProtKB/TrEMBL
InterPro	Aliph_Amidase/BUP	UniProtKB/TrEMBL
	C-N_Hydrolase	UniProtKB/TrEMBL
	C-N_Hydrolase_sf	UniProtKB/TrEMBL
NCBI Gene	UPB1	ENTREZGENE
PANTHER	BETA-UREIDOPROPIONASE	UniProtKB/TrEMBL
	NITRILASE C965.09-RELATED	UniProtKB/TrEMBL
Pfam	CN_hydrolase	UniProtKB/TrEMBL
PROSITE	CN_HYDROLASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56317	UniProtKB/TrEMBL
UniProt	A0A8C0JZL8	ENTREZGENE
	A0A8C0RQR4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0T3I6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PKE2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S5R8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S5S8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NSU7_CANLF	UniProtKB/TrEMBL
	A0A8P0PRA3	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:48149	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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RGD Manual Annotations

Imported Annotations - SMPDB