CCDC85B (coiled-coil domain containing 85B)

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Gene: CCDC85B (coiled-coil domain containing 85B) Canis lupus familiaris

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Symbol:

CCDC85B

Name:

coiled-coil domain containing 85B

RGD ID:

12389903

Description:

ENCODES a protein that exhibits delta-catenin binding (inferred); INVOLVED IN negative regulation of cell growth (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of fat cell differentiation (inferred); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive cutis laxa type IB (ortholog); Bardet-Biedl syndrome (ortholog); FOUND IN adherens junction (inferred); anchoring junction (inferred); centrosome (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 85B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	51,375,015 - 51,376,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	51,375,261 - 51,375,866 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	49,983,525 - 49,984,536 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	52,413,106 - 52,414,117 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	52,413,212 - 52,414,066 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	51,513,175 - 51,514,186 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	51,087,534 - 51,088,545 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	51,876,848 - 51,877,859 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 3 (ISO)

autosomal recessive cutis laxa type IB (ISO)

Bardet-Biedl syndrome (ISO)

glycogen storage disease V (ISO)

intellectual disability (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell growth (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of fat cell differentiation (IEA)

Cellular Component

adherens junction (IEA)

anchoring junction (IEA)

centrosome (IEA)

nucleus (IEA)

Molecular Function

delta-catenin binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

CCDC85B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	51,375,015 - 51,376,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	51,375,261 - 51,375,866 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	49,983,525 - 49,984,536 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	52,413,106 - 52,414,117 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	52,413,212 - 52,414,066 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	51,513,175 - 51,514,186 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	51,087,534 - 51,088,545 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	51,876,848 - 51,877,859 (-)	NCBI		UU_Cfam_GSD_1.0

CCDC85B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	65,890,673 - 65,891,635 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	65,890,673 - 65,891,635 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	65,658,144 - 65,659,106 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	65,414,451 - 65,415,682 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	62,981,782 - 62,983,013 (+)	NCBI		Celera
Cytogenetic Map	11	q13.1	NCBI
HuRef	11	61,984,466 - 61,985,697 (+)	NCBI		HuRef
CHM1_1	11	65,542,289 - 65,543,520 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	65,883,735 - 65,884,697 (+)	NCBI		T2T-CHM13v2.0

Ccdc85b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	5,503,191 - 5,507,591 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	5,503,208 - 5,507,922 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	5,453,163 - 5,457,563 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	5,453,180 - 5,457,894 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	5,453,163 - 5,457,549 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	5,456,539 - 5,457,549 (-)	NCBI		MGSCv36	mm8
Celera	19	5,325,136 - 5,329,522 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	4.33	NCBI

Ccdc85b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	212,192,979 - 212,193,994 (-)	NCBI		GRCr8
mRatBN7.2	1	202,763,645 - 202,764,660 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	202,763,631 - 202,764,703 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	211,115,951 - 211,116,966 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	218,209,051 - 218,210,066 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	210,900,092 - 210,901,107 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	220,835,647 - 220,837,220 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	227,764,980 - 227,766,556 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	208,099,703 - 208,100,997 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	200,299,725 - 200,301,298 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Ccdc85b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	19,432,602 - 19,433,210 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	19,432,368 - 19,433,386 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCDC85B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	67,119,320 - 67,120,171 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	68,161,962 - 68,162,975 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	61,250,913 - 61,251,926 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	64,578,202 - 64,581,942 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

Ccdc85b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	7,207,023 - 7,208,062 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	3,649,613 - 3,650,221 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	3,649,372 - 3,650,408 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC85B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	6,436,794 - 6,437,808 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	6,436,787 - 6,437,828 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	5,540,816 - 5,542,354 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC85B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	8,366,166 - 8,367,670 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	8,366,409 - 8,367,017 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	105,655,347 - 105,656,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc85b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	20,525,942 - 20,526,550 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	20,525,728 - 20,527,337 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CCDC85B
9 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038424940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038501179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038563880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038628006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_861077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000020859 ⟹ ENSCAFP00000019367

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	51,375,261 - 51,375,866 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845030933 ⟹ ENSCAFP00845024242

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	52,413,212 - 52,414,066 (-)	Ensembl

RefSeq Acc Id:

XM_038424940 ⟹ XP_038280868

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	52,413,106 - 52,414,117 (-)	NCBI

RefSeq Acc Id:

XM_038501179 ⟹ XP_038357107

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	18	51,513,175 - 51,514,186 (-)	NCBI

RefSeq Acc Id:

XM_038563880 ⟹ XP_038419808

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	18	51,876,848 - 51,877,859 (-)	NCBI

RefSeq Acc Id:

XM_038628006 ⟹ XP_038483934

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	18	51,087,534 - 51,088,545 (-)	NCBI

RefSeq Acc Id:

XM_861077 ⟹ XP_866170

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	18	51,375,015 - 51,376,044 (-)	NCBI
Dog10K_Boxer_Tasha	18	49,983,525 - 49,984,536 (-)	NCBI

Sequence:

show sequence

GCCCCGCCCCAGCGCGCGCCCCGCCGCGTGCCCACGCCCGGGCGGCTGCTGCAGCCTACGCTAC
CCCGCCACAGCCTGCCGCCCGCGGAGCCGGAGCCCGACCCCGAGCGCGCAGAGCTCGACGTGGG
CTCCTGGGCCGCGGCGGCGGACAGGCGATGCTCCAGAGGCCTGAGCAGCCATGGAGGCCGAGGC
GGGCGGCCTGGAGGAGCTGACGGACGAGGAGATGGCGGCGCTAGGCAAGGAAGAGCTGGTGCGG
CGCCTGCGGCGGGAGGAGGCGGCACGCCTGGCGGCTCTGGTGCAGCGCGGCCGCCTCATGCAGG
AGGTGAATCGGCAGCTGCAGGGTCACCTGGGCGAGATCCGCGAGCTCAAGCAGCTCAACCGGCG
CTTACAGGCGGAGAACCGCGAGCTGCGCGACCTCTGCTGCTTCCTGGACTCGGAGCGCCAGCGC
GGGCGGCGCGCCGCGCGCCAGTGGCAGCTCTTCGGGACCCAAGCATCCCGAGCCGTGCGCGAGG
ACTTGGGCGGTTGTTGGCAGAAGCTGGCCGAGCTGGAGGGCCGCCAGGAGGAGCTGCTGCGGGA
GAACCTGGCGCTTAAGGAGCTCTGCCTGGCTCTGGGTGAGGAGTGGGGCCCCCGGGGCGGCCCC
GGCGGCGCTGGCGGCTCAAGCTCCGGGCCGACACCCGAGCTCGCCTTGCCCCCCTGCGGGCCCC
GCGACCTGGGCGATGGAAGCTCCAGCACCGGCAGCGTGGGCAGTCCAGATCAGTTGCCCCTGGC
CTGCTCCCCGGATGACTGAGGCTCATCTTCCTTCACGTCGACGCCCGACCAGACTGCTTCCCAA
GCGCCGGGACTGCGGTGGACCTCCGGACCCGGACGCCGTCCCGCCTGTGCACGAGGGGCCGCTG
GCATGGATTTGGAAACTCTGGCACCGAGGAGGGCCCCTTGCTTTCTCTTGGTGGGGCAGCAGGG
AGACTGGAGGCTGGAGCGGAGGGACGTGCTGGGAGCGGGGTGGGGGCTAATAAACTGGAACGGA
AGCAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038280868	(Get FASTA)	NCBI Sequence Viewer
	XP_038357107	(Get FASTA)	NCBI Sequence Viewer
	XP_038419808	(Get FASTA)	NCBI Sequence Viewer
	XP_038483934	(Get FASTA)	NCBI Sequence Viewer
	XP_866170	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000019367.4
	ENSCAFP00030023911.1
	ENSCAFP00040024693.1
	ENSCAFP00845024242
	ENSCAFP00845024242.1

RefSeq Acc Id:

XP_866170 ⟸ XM_861077

- UniProtKB:

A0A8C0SQY2 (UniProtKB/TrEMBL), A0A8C0KNT1 (UniProtKB/TrEMBL), A0A8I3P0N6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELK
QLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQE
ELLRENLALKELCLALGEEWGPRGGPGGAGGSSSGPTPELALPPCGPRDLGDGSSSTGSVGSPD
QLPLACSPDD

hide sequence

Ensembl Acc Id:

ENSCAFP00000019367 ⟸ ENSCAFT00000020859

RefSeq Acc Id:

XP_038357107 ⟸ XM_038501179

RefSeq Acc Id:

XP_038483934 ⟸ XM_038628006

RefSeq Acc Id:	XP_038280868 ⟸ XM_038424940
- UniProtKB:	A0A8C0SQY2 (UniProtKB/TrEMBL), A0A8C0KNT1 (UniProtKB/TrEMBL), A0A8I3P0N6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038419808 ⟸ XM_038563880
- UniProtKB:	A0A8C0KNT1 (UniProtKB/TrEMBL), A0A8C0SQY2 (UniProtKB/TrEMBL), A0A8I3P0N6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845024242 ⟸ ENSCAFT00845030933

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013138	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030014872	UniProtKB/TrEMBL
	ENSCAFG00040015439	UniProtKB/TrEMBL
	ENSCAFG00845017470	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020859.6	UniProtKB/TrEMBL
	ENSCAFT00030027403.1	UniProtKB/TrEMBL
	ENSCAFT00040028419.1	UniProtKB/TrEMBL
	ENSCAFT00845030933	ENTREZGENE
	ENSCAFT00845030933.1	UniProtKB/TrEMBL
InterPro	CCDC85	UniProtKB/TrEMBL
KEGG Report	cfa:610847	UniProtKB/TrEMBL
NCBI Gene	CCDC85B	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 85B	UniProtKB/TrEMBL
	PTHR13546	UniProtKB/TrEMBL
Pfam	CCDC85	UniProtKB/TrEMBL
UniProt	A0A8C0KNT1	ENTREZGENE
	A0A8C0SQY2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3P0N6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:38863	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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